Evaluating Chemical and Other Agent Exposures for Reproductive and Developmental Toxicity

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Author :
Publisher : National Academies Press
ISBN 13 : 0309073162
Total Pages : 261 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Evaluating Chemical and Other Agent Exposures for Reproductive and Developmental Toxicity by : National Research Council

Download or read book Evaluating Chemical and Other Agent Exposures for Reproductive and Developmental Toxicity written by National Research Council and published by National Academies Press. This book was released on 2001-04-13 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: The United States Navy has been concerned for some time with protecting its military and civilian personnel from reproductive and developmental hazards in the workplace. As part of its efforts to reduce or eliminate exposure of Naval personnel and their families to reproductive and developmental toxicants, the Navy requested that the National Research Council (NRC) recommend an approach that can be used to evaluate chemicals and physical agents for their potential to cause reproductive and developmental toxicity. The NRC assigned this project to the Committee on Toxicology, which convened the Subcommittee on Reproductive and Developmental Toxicology, to prepare this report. In this report, the subcommittee recommends an approach for evaluating agents for potential reproductive and developmental toxicity and demonstrates how that approach can be used by the Navy. This report has been reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise, in accordance with procedures approved by the NRC's Report Review Committee. The purpose of this independent review is to provide candid and critical comments that will assist the institution in making its published report as sound as possible and to ensure that the report meets institutional standards for objectivity, evidence, and responsiveness to the study charge. The review comments and draft manuscript remain confidential to protect the integrity of the deliberative process. We wish to thank the following individuals for their review of this report: James Chen (National Center for Toxicological Research), George Daston (Procter and Gamble Company), Jerry Heindel (National Institute of Environmental Health Sciences), Grace Lemasters (University of Cincinnati), and John Young (National Center for Toxicological Research).

Pesticides in the Diets of Infants and Children

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Publisher : National Academies Press
ISBN 13 : 0309048753
Total Pages : 402 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Pesticides in the Diets of Infants and Children by : National Research Council

Download or read book Pesticides in the Diets of Infants and Children written by National Research Council and published by National Academies Press. This book was released on 1993-02-01 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many of the pesticides applied to food crops in this country are present in foods and may pose risks to human health. Current regulations are intended to protect the health of the general population by controlling pesticide use. This book explores whether the present regulatory approaches adequately protect infants and children, who may differ from adults in susceptibility and in dietary exposures to pesticide residues. The committee focuses on four major areas: Susceptibility: Are children more susceptible or less susceptible than adults to the effects of dietary exposure to pesticides? Exposure: What foods do infants and children eat, and which pesticides and how much of them are present in those foods? Is the current information on consumption and residues adequate to estimate exposure? Toxicity: Are toxicity tests in laboratory animals adequate to predict toxicity in human infants and children? Do the extent and type of toxicity of some chemicals vary by species and by age? Assessing risk: How is dietary exposure to pesticide residues associated with response? How can laboratory data on lifetime exposures of animals be used to derive meaningful estimates of risk to children? Does risk accumulate more rapidly during the early years of life? This book will be of interest to policymakers, administrators of research in the public and private sectors, toxicologists, pediatricians and other health professionals, and the pesticide industry.

Reproductive Health and the Environment

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Publisher : Springer Science & Business Media
ISBN 13 : 1402048297
Total Pages : 409 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Reproductive Health and the Environment by : P. Nicolopoulou-Stamati

Download or read book Reproductive Health and the Environment written by P. Nicolopoulou-Stamati and published by Springer Science & Business Media. This book was released on 2007-06-04 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews recent trends and developments in the study of the impact that the environment has on human reproduction. It thoroughly examines these issues, using the most modern techniques and methods available, to analyze the manner in which both male and female fertility can be affected and assessed. Coverage examines such diverse factors as toxic environmental contaminants, air pollution, and exposure to medical drugs.

Handbook of Developmental Neurotoxicology

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Publisher : Academic Press
ISBN 13 : 0128093943
Total Pages : 618 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Handbook of Developmental Neurotoxicology by : William Slikker Jr.

Download or read book Handbook of Developmental Neurotoxicology written by William Slikker Jr. and published by Academic Press. This book was released on 2018-01-04 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Developmental Neurotoxicology, Second Edition, provides a comprehensive view of the fundamental aspects of neurodevelopment, the pathways and agents that affect them, relevant clinical syndromes, and risk assessment procedures for developmental neurotoxicants. The editors and chapter authors are internationally recognized experts whose collaboration heralds a remarkable advance in the field, bridging developmental neuroscience with the principles of neurotoxicology. The book features eight new chapters with newly recruited authors, making it an essential text for students and professionals in toxicology, neurotoxicology, developmental biology, pharmacology, and neuroscience. - Presents a comprehensive, up-to-date resource on developmental neurotoxicology with updated chapters from the first edition - Contains new chapters that focus on subjects recent to the field - Includes well-illustrated material, with diagrams, charts, and tables - Contains compelling case studies and chapters written by world experts

Neurotoxicity of Pesticides

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Publisher : Academic Press
ISBN 13 : 0128205156
Total Pages : 288 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Neurotoxicity of Pesticides by :

Download or read book Neurotoxicity of Pesticides written by and published by Academic Press. This book was released on 2020-03-21 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurotoxicity of Pesticides, Volume Four, in this comprehensive serial addresses contemporary advances in neurotoxicology of pesticides by providing authoritative review articles on key issues in the field. Edited by leading subject experts, topics of note in this new release include Organophosphates, OPs, Nerve agents, Pyrethroids, Neonicotinoids and Formamidines, among others.

Drinking Water and Health,

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Publisher : National Academies Press
ISBN 13 : 0309036879
Total Pages : 476 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Drinking Water and Health, by : National Research Council

Download or read book Drinking Water and Health, written by National Research Council and published by National Academies Press. This book was released on 1986-02-01 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most recent volume in the Drinking Water and Health series contains the results of a two-part study on the toxicity of drinking water contaminants. The first part examines current practices in risk assessment, identifies new noncancerous toxic responses to chemicals found in drinking water, and discusses the use of pharmacokinetic data to estimate the delivered dose and response. The second part of the book provides risk assessments for 14 specific compounds, 9 presented here for the first time.

Science and Judgment in Risk Assessment

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Publisher : National Academies Press
ISBN 13 : 030904894X
Total Pages : 668 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Science and Judgment in Risk Assessment by : National Research Council

Download or read book Science and Judgment in Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 1994-01-01 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: The public depends on competent risk assessment from the federal government and the scientific community to grapple with the threat of pollution. When risk reports turn out to be overblownâ€"or when risks are overlookedâ€"public skepticism abounds. This comprehensive and readable book explores how the U.S. Environmental Protection Agency (EPA) can improve its risk assessment practices, with a focus on implementation of the 1990 Clean Air Act Amendments. With a wealth of detailed information, pertinent examples, and revealing analysis, the volume explores the "default option" and other basic concepts. It offers two views of EPA operations: The first examines how EPA currently assesses exposure to hazardous air pollutants, evaluates the toxicity of a substance, and characterizes the risk to the public. The second, more holistic, view explores how EPA can improve in several critical areas of risk assessment by focusing on cross-cutting themes and incorporating more scientific judgment. This comprehensive volume will be important to the EPA and other agencies, risk managers, environmental advocates, scientists, faculty, students, and concerned individuals.

Scientific Frontiers in Developmental Toxicology and Risk Assessment

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Publisher : National Academies Press
ISBN 13 : 0309070864
Total Pages : 348 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Scientific Frontiers in Developmental Toxicology and Risk Assessment by : National Research Council

Download or read book Scientific Frontiers in Developmental Toxicology and Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2000-12-21 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.

Exposure and Risk Assessment of Chemical Pollution - Contemporary Methodology

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Publisher : Springer Science & Business Media
ISBN 13 : 9048123356
Total Pages : 538 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Exposure and Risk Assessment of Chemical Pollution - Contemporary Methodology by : Mahmoud A. Hassanien

Download or read book Exposure and Risk Assessment of Chemical Pollution - Contemporary Methodology written by Mahmoud A. Hassanien and published by Springer Science & Business Media. This book was released on 2009-03-31 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book contains the contributions at the NATO Study Institute on Exposure and Risk Assessment of Chemical Pollution – Contemporary Methodology, which took place in Sofia – Borovetz, Bulgaria, July 1–10, 2008. Rapid advances in mathematics, computer science and molecular biology and chemistry have lead to the development in of a new branch of toxicology called Computational Toxicology. This emerging field is addressing the estimation and prediction of exposure risk and effects of chemicals based on experimental data, measured concentration and biological mechanisms and computational models of biological systems. Mathematical models are also being used to predict the fate and transport of substances in the environment. Because this area is still in its infancy, there has been limited application from governmental agencies to regulating controllable processes, such as registration of new chemicals, determination of estimated exposure and risk based limits and maximum acceptable concentrations in different compartments of the environment – ambient air, waters, soil and food products. However, this is soon to change as the ability to collect, analyze and interpret the required information is becoming increasingly more efficient and cost effective. Full implementation of the new processes have to involve education on both part of the experimentalists who are generating the data and the models, and the risk assessors who will use them to better protect human health and the environment.

Current Epidemiological Evidence Versus Experimental Data on Reproductive and Developmental Toxicity of Pesticides

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Publisher :
ISBN 13 : 9789549092417
Total Pages : 279 pages
Book Rating : 4.0/5 (924 download)

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Book Synopsis Current Epidemiological Evidence Versus Experimental Data on Reproductive and Developmental Toxicity of Pesticides by : Tatjana Vergieva

Download or read book Current Epidemiological Evidence Versus Experimental Data on Reproductive and Developmental Toxicity of Pesticides written by Tatjana Vergieva and published by . This book was released on 2001 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This paper reviews epidemiological and experimental datas well as methodological issues pertinent ot the evaluation of the studies exploring the risk of prenatal toxicity associated with parental exposure to pesticides. The following main relevant factors to be considered when planning research in the field have been listed: pesticides should not be regarded as a homogenous group of chemical agents, their levels in environment are very low (except due to misuse and accidents) and the adverse health effects to be expected would be of low severity and of low incidence, as with other chemicals (drugs for example), level and timing of exposure are major determinant. A special attention is given to the lack of biological plausibility and relevant data to support epidemiological findings about a higher risk of male mediated development toxicity.

Reproductive and Developmental Toxicology

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Publisher : Academic Press
ISBN 13 : 0323915604
Total Pages : 1558 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Reproductive and Developmental Toxicology by : Ramesh C Gupta

Download or read book Reproductive and Developmental Toxicology written by Ramesh C Gupta and published by Academic Press. This book was released on 2022-02-11 with total page 1558 pages. Available in PDF, EPUB and Kindle. Book excerpt: **Selected for Doody's Core Titles® 2024 in Toxicology** Reproductive and Developmental Toxicology, Third Edition is a comprehensive and authoritative resource, providing the latest literature on this complex subject by focusing on three core components - parent, placenta and fetus - and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, and metals, among others. In addition, it is the only resource to include reproductive and developmental toxicity in domestic animals, fish and wildlife With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages. Completely revised and updated to include the most recent developments in the field, this book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists and teratologists from academia, industry and regulatory agencies. - Provides a complete, up-to-date, integrated source of information on the key risk stages during reproduction and development - Offers diverse and unique in vitro and in vivo toxicity models for reproductive and developmental toxicity testing in a user-friendly format that assists in comparative analysis - Includes new chapters on developments in systems toxicology and predictive modeling of male developmental toxicity, adverse outcome pathways in reproductive and developmental toxicology, ovarian and endometrial toxicity, developmental neurotoxicity of air pollution, and more

Toxicological Profile for Aldrin/dieldrin :.

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (126 download)

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Book Synopsis Toxicological Profile for Aldrin/dieldrin :. by :

Download or read book Toxicological Profile for Aldrin/dieldrin :. written by and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pesticides

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Publisher : John Wiley & Sons
ISBN 13 : 1405172983
Total Pages : 249 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Pesticides by : Graham Matthews

Download or read book Pesticides written by Graham Matthews and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last five decades pesticides have undoubtedly helped toincrease agricultural production and control vectors of disease,however the environmental impact of long term agro-chemical use hasbeen cause for concern along with the effects on human health. In Pesticides, Graham Matthews begins by looking at thedevelopmental history of pesticides, and how crop protection wasachieved before they were in use, how pesticides are registered foruse and what happens to pesticides in food and the environment.Pesticide application and operator safety is investigated and thefuture of pesticides in light of the development of geneticallymodified crops is explored. Provides commercially important information for theagro-chemical industry Addresses all aspects of public concern relating to humanhealth and the environment, including spray drift, bystander,resident and worker exposure Looks at the future of pesticides in light of the increasingprevalence of genetically modified crops Collecting together the most recent research in the area in asingle volume, this book is a vital resource for agriculturalscientists, agronomists, plant scientists, plant pathologists,entomologists, environmental scientists, public health personnel,toxicologists, crop protection personnel and all those involved inthe agrochemical industry and government pesticide registration andlegislation.

Environmental Security Assessment and Management of Obsolete Pesticides in Southeast Europe

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Publisher : Springer
ISBN 13 : 9400764618
Total Pages : 481 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Environmental Security Assessment and Management of Obsolete Pesticides in Southeast Europe by : Lubomir I. Simeonov

Download or read book Environmental Security Assessment and Management of Obsolete Pesticides in Southeast Europe written by Lubomir I. Simeonov and published by Springer. This book was released on 2014-07-08 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present work is a fine contribution to the broad field of environmental security in the context of risk assessment and management of obsolete pesticides for the region of Southeast Europe. The purpose of this book is to evaluate the existing knowledge of improper disposal of obsolete pesticides in the region, to estimate the associated impact on environmental health, and to develop recommendations to mitigate or eliminate threats posed to the environment, biodiversity and human life. The issues discussed in the book include: reviews of the transport and fate of pesticides and associated contaminated materials in different environmental media and identification of the principal sources, emission routes and patterns of environmental pollution with pesticides; a recognition of the most suitable methods for environmental sampling analysis and sample preparation; an evaluation of the current methods and techniques for chemical and mass analysis of environmental and biological samples and discussion of the metrological and quality aspects of trace analyses; a characterization of the environmental and human health impacts of pesticide pollution, the health effects associated with acute and chronic exposure and the use of epidemiological data for risk assessment; a revision of the existing chemical safety regulations and strategies for protection and management of obsolete pesticide stocks; a survey of the international conventions, directives and standards concerning pesticide use.

Toxicological Profile for Pyrethrins and Pyrethroids

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Publisher :
ISBN 13 :
Total Pages : 334 pages
Book Rating : 4.3/5 (91 download)

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Download or read book Toxicological Profile for Pyrethrins and Pyrethroids written by and published by . This book was released on 2003 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pesticide Toxicology

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Publisher :
ISBN 13 : 9781071619285
Total Pages : pages
Book Rating : 4.6/5 (192 download)

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Book Synopsis Pesticide Toxicology by : Eugenia Gallardo

Download or read book Pesticide Toxicology written by Eugenia Gallardo and published by . This book was released on 2022 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume explores practical procedures on the identification and quantification of pesticides in a variety of samples. Chapters guide the reader through methods and protocols for the extraction of pesticides from biological and non-biological samples, pitfalls in dosing techniques and structures identification, and also provide an overview of the problems that these pesticides cause in human populations. As part of the Methods in Pharmacology and Toxicology series, chapters include introductions to their respective topics, lists of reagents and materials, step-by-step guides and reproducible lab protocols, as well as valuable tips on addressing common problems and avoiding known pitfalls. Authoritative and practical, Pesticide Toxicology is an ideal reference for academia, analysts, toxicologists, environmentalists, and health and industry professionals aiming to understand the associated risks and to limit the use of these substances and minimize their potential damage to human health and the environment.

Toxicological Profile for Chlordane

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Publisher :
ISBN 13 :
Total Pages : 286 pages
Book Rating : 4.:/5 (321 download)

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Book Synopsis Toxicological Profile for Chlordane by :

Download or read book Toxicological Profile for Chlordane written by and published by . This book was released on 1994 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: