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Download Cross Talk Among Myeloid Derived Suppressor Cells Macrophages And Tumor Cells Impacts The Inflammatory Milieu Of Solid Tumors full books in PDF, epub, and Kindle. Read online Cross Talk Among Myeloid Derived Suppressor Cells Macrophages And Tumor Cells Impacts The Inflammatory Milieu Of Solid Tumors ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Download or read book Cross‐talk Among Myeloid‐derived Suppressor Cells, Macrophages, and Tumor Cells Impacts the Inflammatory Milieu of Solid Tumors written by and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Elsevier
ISBN 13 : 044319128X
Total Pages : 242 pages
Book Rating : 4.4/5 (431 download)
Download or read book Myeloid-Derived Suppressor Cells written by and published by Elsevier. This book was released on 2023-03-23 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myeloid-Derived Suppressor Cells, Volume 375 includes comprehensive and detailed reviews on the current advances in myeloid derived suppressor cells, an immature, heterogenous cell population from the myeloid lineage that has been extensively described in the last decades due to its potent immunosuppressive activity in a variety of pathologies. Chapters in this new release include Cancer-cell-intrinsic mechanisms regulate myeloid-derived suppressor cells through cytokine networks, Role of myeloid-derived suppressor cells in head and neck cancer, Role of myeloid-derived suppressor cells in breast cancer, Role of myeloid-derived suppressor cells in endometriosis, Role of myeloid-derived suppressor cells in ovarian cancer, Role of myeloid-derived suppressor cells in sarcoma, and more. Contains chapters led by selected experts on the topic of myeloid-derived suppressor cells Includes comprehensive and detailed knowledge on myeloid-derived suppressor cells in different diseases Offers a wide range of perspectives on specific diseases
Author : Olivera J. Finn
Publisher : Frontiers Media SA
ISBN 13 : 2889636771
Total Pages : 162 pages
Book Rating : 4.8/5 (896 download)
Download or read book Myeloid Derived Suppressor Cells as Disease Modulators written by Olivera J. Finn and published by Frontiers Media SA. This book was released on 2020-05-06 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myeloid Derived Suppressor Cells (MDSCs) are a heterogeneous population of immature myeloid cells that can suppress the function of multiple immune cells and in particular, T cells, through various mechanisms. MDSCs can be divided into two major subtypes based on their cell surface phenotype and morphology: polymorphonuclear MDSC (PMN-MDSC or G-MDSC) and monocytic MDSC (M-MDSC). Additional subtypes have been proposed, such as the early MDSC (e-MDSC) that lack both macrophage and granulocyte markers. There is still considerable ambiguity about the phenotype of these cells that corresponds to their immunosuppressive function and there are on-going challenges on how to identify, purify and/or potentially generate and expand these cells in vitro. MDSCs were first discovered in cancer patients where they have been most extensively studied as components of the immunosuppressive tumor microenvironment. In the last several years, however, the importance of their immunomodulatory role in many other disease and clinical settings has emerged. Acknowledgments We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). We hereby state publicly that the IUIS has had no editorial input in articles included in this Research Topic, thus ensuring that all aspects of this Research Topic are evaluated objectively, unbiased by any specific policy or opinion of the IUIS.
Author : Erika Adriana Eksioglu
Publisher : Frontiers Media SA
ISBN 13 : 2832541496
Total Pages : 131 pages
Book Rating : 4.8/5 (325 download)
Download or read book Therapeutic targeting Of MDSC in the tumor and immune microenvironment written by Erika Adriana Eksioglu and published by Frontiers Media SA. This book was released on 2023-12-18 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : David Escors
Publisher : Springer
ISBN 13 : 331926821X
Total Pages : 109 pages
Book Rating : 4.3/5 (192 download)
Download or read book Myeloid-Derived Suppressor Cells and Cancer written by David Escors and published by Springer. This book was released on 2016-03-15 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting. It closes with an outlook on future developments. In cancer patients, myelopoiesis is perturbed and instead of generating immunogenic myeloid cells (such as dendritic cells, inflammatory macrophages and granulocytes), there is an increase in highly immature MDSCs. These cells are distributed systemically, resulting in general immunosuppression. They also infiltrate tumours, promoting their progression and metastasis by inhibiting the natural anti-tumour immune response. As these cells also interact with classical anti-neoplastic treatments, they have become major therapeutic targets in the pharmaceutical industry and in oncology research.
Author : Anahid Jewett
Publisher : Academic Press
ISBN 13 : 0128226269
Total Pages : 496 pages
Book Rating : 4.1/5 (282 download)
Download or read book NK Cells in Cancer Immunotherapy: Successes and Challenges written by Anahid Jewett and published by Academic Press. This book was released on 2022-12-06 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: NK Cells in Cancer Immunotherapy: Successes and Challenges explains the latest immunotherapeutic strategies, focusing on NK cells to allow the best and precise combination treatments to cancer patients. The book provides existing background knowledge in the field of immunotherapy and discusses future areas of research required to carry out cutting-edge, validated therapies. Chapters cover advances in immunotherapeutic strategies, in particular, the use of NK cells with and without T-cell therapy in the treatment of cancer. The book is a valuable resource for cancer researchers, oncologists, graduate students and those interested in learning more about novel strategies to treat cancer patients. Immunotherapy is fast becoming the method of choice for cancer therapy. Although remarkable advances have been made in the field of immunotherapy, there are significant challenges and difficulties ahead since many of the current immunotherapeutic strategies do not provide long-lasting treatment strategies, and therefore are not very effective. Covers CAR/T and CAR/NK and adoptive NK cell therapy with and without T cell therapies Discusses basic biology of NK cells and mouse models of human cancers and the role of NK cells in metastatic cancer and in cancer stem cells Encompasses information on combination therapies using check point inhibition, adoptive transfer of cytotoxic effector cells, chemotherapeutic drugs and activating and inhibitory antibodies
Author : Bharat B. Aggarwal
Publisher : Springer
ISBN 13 : 3034808372
Total Pages : 489 pages
Book Rating : 4.0/5 (348 download)
Download or read book Inflammation and Cancer written by Bharat B. Aggarwal and published by Springer. This book was released on 2014-05-12 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.
Author : Nicolas Larmonier
Publisher : Frontiers Media SA
ISBN 13 : 2832519504
Total Pages : 198 pages
Book Rating : 4.8/5 (325 download)
Download or read book Tumor-promoting immune cells: Cancer immune escape and beyond written by Nicolas Larmonier and published by Frontiers Media SA. This book was released on 2023-03-31 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Daniel P. Bezerra
Publisher : Frontiers Media SA
ISBN 13 : 2832527892
Total Pages : 626 pages
Book Rating : 4.8/5 (325 download)
Download or read book Reviews in Molecular and Cellular Oncology written by Daniel P. Bezerra and published by Frontiers Media SA. This book was released on 2023-07-06 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Sergei Kusmartsev
Publisher : Frontiers Media SA
ISBN 13 : 2889714985
Total Pages : 202 pages
Book Rating : 4.8/5 (897 download)
Download or read book Roles of Tumor-Recruited Myeloid Cells in Immune Evasion in Cancer written by Sergei Kusmartsev and published by Frontiers Media SA. This book was released on 2021-10-18 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Academic Press
ISBN 13 : 0128025549
Total Pages : 407 pages
Book Rating : 4.1/5 (28 download)
Download or read book Immunotherapy of Cancer written by and published by Academic Press. This book was released on 2015-07-29 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunotherapy of Cancer provides information on cancer research related to inflammation and immunity, containing outstanding reviews by experts in the field. It is suitable for researchers and students who have an interest in cancer immunobiology. Provides information on cancer research, including outstanding and original reviews Covers the current progress and emerging concepts in cancer inflammation, immunology, and immunotherapy Suitable for researchers and students studying, and interested in, the field of immunotherapy for cancer Ideal for those studying cancer inflammation, tumor immunology, cancer immunotherapy, dendritic cell, antigen presentation, immune checkpoint, myeloid-derived suppressor cells, macrophages, and tumor environments
Author : Peng Qu
Publisher : Frontiers Media SA
ISBN 13 : 2889748405
Total Pages : 792 pages
Book Rating : 4.8/5 (897 download)
Download or read book Manipulating the Immunological Tumor Microenvironment written by Peng Qu and published by Frontiers Media SA. This book was released on 2022-03-31 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Alexander Birbrair
Publisher : Springer Nature
ISBN 13 : 3030357236
Total Pages : 153 pages
Book Rating : 4.0/5 (33 download)
Download or read book Tumor Microenvironment written by Alexander Birbrair and published by Springer Nature. This book was released on 2020-02-08 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: Revealing essential roles of the tumor microenvironment in cancer progression, this book focuses on the role of hematopoietic components of the tumor microenvironment. Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include neutrophils, basophils, T helper cells, cytotoxic lymphocytes, fibrocytes, and myeloid-derived suppressor cells, and more. Taken alongside its companion volumes, these books update us on what we know about various aspects of the tumor microenvironment as well as future directions. Tumor Microenvironment: Hematopoietic Cells – Part A is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
Author : Anwen Shao
Publisher : Frontiers Media SA
ISBN 13 : 2832550320
Total Pages : 156 pages
Book Rating : 4.8/5 (325 download)
Download or read book Reactive Oxygen Species (ROS): Key Components in Cancer Immunotherapy written by Anwen Shao and published by Frontiers Media SA. This book was released on 2024-06-12 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: The class of highly bioactive chemicals known as reactive oxygen species (ROS) has been extensively explored in relation to several malignancies and is thought to be a typical by-product of many cellular functions. Cancer cells have greater baseline ROS concentrations than healthy cells because of an imbalance between oxidants and antioxidants. At low to moderate levels, ROS functions as a signal transducer to drive cell proliferation, migration, invasion, and angiogenesis. ROS also has a second role in cellular metabolism. On the other hand, excessive ROS may kill cells by harming organelles, membranes, lipids, proteins, and nucleic acids. Numerous studies have shown that anticancer treatments that regulate ROS levels, such as immunotherapy, provide encouraging outcomes both in vitro and in vivo.
Author : Sayali Mukherjee
Publisher : CRC Press
ISBN 13 : 1351166549
Total Pages : 662 pages
Book Rating : 4.3/5 (511 download)
Download or read book Rediscovering Cancer: From Mechanism to Therapy written by Sayali Mukherjee and published by CRC Press. This book was released on 2018-09-04 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents a snapshot of some of the most important ongoing research in cancer. With cancer as the second leading cause of death worldwide, extensive research is going on globally to decipher the molecular mechanism underlying cancer that will help in finding better targets for drug therapy. The book brings together new research on molecular mechanism and cancer therapeutics in one place. With chapters from experts in their respective fields, chapters cover molecular mechanisms, etiology, prognosis, detection, and treatment of cancer. Emphasis has been given to the intricate mechanism behind the deregulation of cell division, disruption of cell cycle check points, mutation in oncogenes and tumor suppressor genes, apoptosis, and erratic cell signaling. The book discusses in detail topics such as angiogenesis and tumor microenvironment, which are increasingly receiving attention, especially in the field of neoplastic vascularization and metastasis. The book also includes chapters detailing the current understanding and the future perspective of cancer stem cells.
Author : Catherine Alix-Panabieres
Publisher : MDPI
ISBN 13 : 3039286986
Total Pages : 366 pages
Book Rating : 4.0/5 (392 download)
Download or read book Circulating Tumor Cells written by Catherine Alix-Panabieres and published by MDPI. This book was released on 2020-04-03 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: The analysis of circulating tumor cells (CTCs) as a real-time liquid biopsy approach can be used to obtain new insights into metastasis biology, and as companion diagnostics to improve the stratification of therapies and to obtain insights into the therapy-induced selection of cancer cells. In this book, we will cover all the different facets of CTCs to assemble a huge corpus of knowledge on cancer dissemination: technologies for their enrichment, detection, and characterization; their analysis at the single-cell level; their journey as CTC microemboli; their clinical relevance; their biology with the epithelial-to-mesenchymal transition (EMT); their stem-cell properties; their potential to initiate metastasis at distant sites; their ex vivo expansion; and their escape from the immune system.
Author : John H. Sampson
Publisher : Academic Press
ISBN 13 : 0128026251
Total Pages : 406 pages
Book Rating : 4.1/5 (28 download)
Download or read book Translational Immunotherapy of Brain Tumors written by John H. Sampson and published by Academic Press. This book was released on 2017-02-06 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Immunotherapy of Brain Tumors gives researchers and practitioners an up-to-date and comprehensive overview of the field. Chapters include adoptive immunotherapy, immunosuppression, CAR therapy of brain tumors, and dendritic cell therapy for brain tumors. Very few agents have been shown to be efficacious in the treatment of malignant gliomas. Recently, there have been a number of studies demonstrating the potential success of immunotherapy for brain tumors. Immunotherapeutics are becoming the most frequent drugs to be used in cancer therapy. These new breakthroughs, now approved by the FDA, are a part of multiple phase III international trials and ongoing research in malignant glioma, meaning that the information in this cutting-edge book will be of great importance to practitioners and researchers alike. Comprehensive overview, providing an update on immunology, translational immunotherapy, and clinical trials relating to malignant gliomas Edited by a prominent neurosurgeon with contributions by leading researchers in the field Ideal resource for researchers and practitioners interested in learning about mechanisms that use the immune system to treat brain tumors
