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Corneal Infection And Inflammation
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Book Synopsis Corneal Infection and Inflammation by : Noopur Gupta
Download or read book Corneal Infection and Inflammation written by Noopur Gupta and published by CRC Press. This book was released on 2021-06-20 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive treatise on infective and inflammatory pathologies of the cornea with corresponding clinical images and diagrammatic illustrations. Corneal infections and inflammations are a major cause of ocular morbidity and visual impairment. Early diagnosis and treatment can lead to improved visual outcome and quality of life. Both infectious (bacterial, fungal, viral and protozoan) and non-infectious keratitis that cause corneal vascularisation, scarring and vision loss are covered extensively. The illustrated clinical findings presented in the form of diagrams, photographs, cases and videos aim to serve as a practical teaching tool for fellows, trainees and practising ophthalmologists. KEY FEATURES Focuses on clinically relevant parts of corneal diseases, using illustrations with arrows indicating different pathologies and signs Serves as a ready clinical compendium for trainees, fellows and ophthalmologists Explores various corneal pathologies through a wealth of accompanying illustrations and teaching videos
Book Synopsis Infections of the Cornea and Conjunctiva by : Sujata Das
Download or read book Infections of the Cornea and Conjunctiva written by Sujata Das and published by Springer Nature. This book was released on 2020-11-27 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the clinical features, invasive and non-invasive modalities of diagnosis of conjunctival and corneal infections, especially atypical clinical situations in unusual cases of keratitis, and manage the disease entity. Infections of cornea continues to be the leading cause of ocular morbidity and blindness worldwide. Early diagnosis helps in better outcome. Proper understanding of the microbiological and clinical characteristics of this disease entity enables ophthalmologists to initiate appropriate therapy. Corneal infections, especially due to uncommon organisms, are difficult to diagnose and treat. With 17 chapters, this volume covers the entire spectrum of corneal and conjunctival infections. This is a quick go-to book for general as well as specialist ophthalmologists.
Book Synopsis Corneal Infection and Inflammation by : Richard Charles Troutman
Download or read book Corneal Infection and Inflammation written by Richard Charles Troutman and published by . This book was released on 1990 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mycotic Keratitis written by Mahendra Rai and published by CRC Press. This book was released on 2019-07-23 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mycotic keratitis, also known asfungal keratitis, is commonly defined as an inflammation of the cornea. Globally, mycotic keratitis is more common as compared to others eye disorders. Though it occurs in all parts of the world it is more prevalent in tropical and subtropical areas. Mycotic Keratitis emphasizes novel perspectives on mycotic keratitis treatments and addresses different therapies used in treatment. The book is designed to be immensely useful for the students and teachers of microbiology, medicine, mycology, ophthalmology, biotechnology and nanotechnology. Medical microbiology researchers in general and medical mycology in particular will find it a valuable user-friendly book.
Book Synopsis Peripheral Ulcerative Keratitis by : Radhika Tandon
Download or read book Peripheral Ulcerative Keratitis written by Radhika Tandon and published by Springer. This book was released on 2017-03-09 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: A handy manual for cornea specialists, this book provides detailed practical information about a complex, sight-threatening disease that can be challenging to diagnose and manage. This text features chapters dedicated to outlining all facets of diagnosis and management while covering both medical and surgical treatment options. Peripheral Ulcerative Keratitis, supplemented with useful references and appendices to provide simple step by step algorithms, is written by internationally renowned authors who are experts in the field.Including practical tips and guidelines for diagnosis and therapy of these disorders, Peripheral Ulcerative Keratitis is designed to serve as a guide for comprehensive ophthalmologists and should find itself on the bookshelves of ophthalmology clinics, corneal practices and training programs across the country.
Book Synopsis Common Eye Infections by : Imtiaz Chaudhry
Download or read book Common Eye Infections written by Imtiaz Chaudhry and published by BoD – Books on Demand. This book was released on 2013-05-08 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since ocular infections are one of the most frequent occurrences in ophthalmology, the treatment for these infections must be fast, precise and effective. In order to address this goal, it is important to identify and characterize the culprit microorganisms involved in the pathogenesis of ocular infections. Clinical diagnosis of ocular infections can be confirmed by several techniques based on microbiological test of ocular samples. Some of these techniques include classic microbiological testing in which it is necessary to isolate microorganisms to characterize them by biochemical analysis which require significant resources and timing.
Download or read book Keratitis written by Muthiah Srinivasan and published by BoD – Books on Demand. This book was released on 2012-04-25 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 4 chapters in this book focus on investigation, basic and advanced clinical aspects and management of frequently encountered corneal disorders. The authors have covered keratitis theory and practice. Onchocersias, even though found on one continent, has its impact on population, epidemiologists, ophthalmologists, NGOs, public health planners and care providers. The goal of this book is to provide information on ancient eye diseases; their investigation and management to prevent corneal blindness. I acknowledge the great help rendered by Publishing Process Manager and Editor Relations Consultant.
Book Synopsis Immunology, Inflammation and Diseases of the Eye by : Darlene A. Dartt
Download or read book Immunology, Inflammation and Diseases of the Eye written by Darlene A. Dartt and published by Academic Press. This book was released on 2011-05-05 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: This selection of articles from the Encyclopedia of the Eye provides a comprehensive overview of immunological features, diseases and inflammation of the eye and its support structures and organs. Rather than taking an immunological focus that is strictly suitable for clinicians, the volume offers a considerable basic science background and addresses a broad range of topics - the immune system of the eye, its various disorders, mechanisms of inflammation of the eye and visual system, treatment, wound healing mechanisms, stem cells, and more. The first single volume to integrate comparative studies into a comprehensive resource on the neuroscience of ocular immunology Chapters are carefully selected from the Encyclopedia of the Eye by the world's leading vision researchers The best researchers in the field provide their conclusions in the context of the latest experimental results
Author :Pierfrancesco Mirabelli Publisher :Linköping University Electronic Press ISBN 13 :9176850641 Total Pages :91 pages Book Rating :4.1/5 (768 download)
Book Synopsis Inhibitors of corneal inflammation and angiogenesis by : Pierfrancesco Mirabelli
Download or read book Inhibitors of corneal inflammation and angiogenesis written by Pierfrancesco Mirabelli and published by Linköping University Electronic Press. This book was released on 2019-04-30 with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathologic angiogenesis is involved in cancer and several blinding conditions such as wet age-related macular degeneration, proliferative retinopathies and corneal neovascularization. In these dieseases, the angiogenic triggers are hypoxia and inflammation, and both involve the main angiogenic mediator, which is Vascular Endothelial Growth Factor (VEGF). Among available treatments, anti-VEGF often shows limited or temporary efficacy, while steroids are potentially responsible for many side-effects. This thesis presents a series of linked studies aimed at elucidating the early pathologic changes leading to inflammation and corneal neovascularization, and how various treatments affect this process. In this thesis, anti-inflammatory and anti-angiogenic treatments are applied in corneal neovascularization models, to identify VEGF-independent pathways and other novel factors as future therapy targets, as well as to investigate the endogenous modulation of angiogenesis. A model of experimental neovascularization in the rat cornea was used as main model, where the neovascular response is triggered by a surgical suture placed into the cornea. Investigational treatments (anti-Vegf, dexamethasone, IMD0354, Gap27, or control substances) were then given topically, with the exception of IMD0354, which was given systemically. The effects in the cornea were studied in vivo with slit lamp photography to assess and quantify macroscopic vessel growth and using in vivo confocal microscopy (IVCM) to study cell infiltration and limbal vessel dilation and detect microscopic vessel sprouts; these examinations were performed longitudinally. Genomic analysis with RNA microarray, selected gene expression with q-RT-PCR, and selected protein expression in tissue (immunohistochemistry, immunofluorescence, Western blot) were performed at different time-points. Moreover, other experiments on cell cultures (HUVEC and HCEC), organ cultures (human corneas), ex vivo models (aortic rings) and in vivo studies (zebrafish vasculogenesis) were performed. Dexamethasone suppressed limbal vasodilation and corneal neovascularization more than anti-Vegf, despite no difference in inflammatory cell infiltration into the cornea. Five-hundred eleven fewer genes were differentially expressed in dexamethasone-treated corneas relative to naïve corneas, compared to anti-Vegf. Among them, several major pro-angiogenic and pro-inflammatory factors and chemokines were suppressed only by dexamethasone and represent novel candidate factors to target in order to improve anti-VEGF treatment. On the other hand, selective inhibition of a single inflammatory pathway (NF-?B), despite showing similar early effects as dexamethasone in suppressing tissue inflammation, was not effective enough to suppress new vessel growth. The same factors suppressed by dexamethasone are also inhibited in endogenous modulation of angiogenesis. Surprisingly, dexamethasone activated several complement factors, which could possibly be beneficial in the anti-angiogenic response. In a different therapeutic approach, promoting cell migration to accelerate epithelial wound closure similarly was not sufficient to avoid inflammation and angiogenesis in the cornea. In conclusion, new and more effective treatments are needed for corneal inflammation and neovascularization with fewer side-effects. In this thesis, several novel factors and mechanisms related to inflammation are identified, factors that are not addressed by anti-Vegf therapy, and therefore represent interesting objects for further study, as they have the potential to be targets for adjuvant therapy. Specific anti-inflammatory treatment as well as therapeutic activation of endogenous regulatory pathways, and potentially complement modulation, might represent new strategies to improve anti-angiogenic therapy, but when used alone they do not seem to avoid corneal neovascularization.
Book Synopsis Diagnosis & Treatment of Uveitis by : C Stephen Foster
Download or read book Diagnosis & Treatment of Uveitis written by C Stephen Foster and published by JP Medical Ltd. This book was released on 2013-03-30 with total page 1326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uveitis is inflammation of the middle layer of the eye, which is known as the uvea or uveal tract. It is a complex condition with a variety of causes and clinical manifestations, including injury, infection or an underlying condition. This 1200pp second edition brings ophthalmologists fully up to date with the latest developments in diagnosing and treating uveitis. Beginning with the basic principles of the disease, its diagnosis and management, the following sections discuss the treatment of numerous different infectious, non infectious, masquerade and autoimmune syndromes. Basic science, differential diagnosis, pathology and clinical management are discussed for each condition. Written by specialists from the Massachusetts Eye Research and Surgery Institution (MERSI) and John A Moran Eye Center in the USA, this comprehensive new edition includes 699 colour images and illustrations. Key points Comprehensive, second edition bringing ophthalmologists fully up to date with diagnosis and treatment of uveitis Discusses different uveitis syndromes – infectious, non infectious, masquerade and autoimmune Authored by US ophthalmic specialists Includes 699 full colour images and illustrations First edition published in 2001 by Saunders
Book Synopsis Regulation of inflammation and angiogenesis in the cornea by : Anthony Mukwaya
Download or read book Regulation of inflammation and angiogenesis in the cornea written by Anthony Mukwaya and published by Linköping University Electronic Press. This book was released on 2018-05-21 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammation and angiogenesis, the growth of new blood vessels from pre-existing ones, are involved in tumor growth, ocular diseases and wound healing. In ocular angiogenesis, new pathological vessels grow into a specific eye tissue, leak fluid, and disrupt vision. The development of safe and effective therapies for ocular angiogenesis is of great importance for preventing blindness, given that current treatments have limited efficacy or are associated with undesirable side effects. The search for alternative treatment targets requires a deeper understanding of inflammation and how it can lead to angiogenesis in the eye in pathologic situations. This thesis provides new insights into the regulation of inflammation and angiogenesis, particularly at the gene expression and phenotypic levels, in different situations characterized by angiogenesis of the cornea, often called corneal neovascularization. For instance, specific genes and pathways are either endogenously activated or suppressed during active inflammation, wound healing, and during resolution of inflammation and angiogenesis, serving as potential targets to modulate the inflammatory and angiogenic response. In addition, as part of the healing response to restore corneal transparency, inflammation and angiogenesis subside with time in the cornea. In this context, LXR/RXR signaling was found to be activated in a time-dependent manner, to potentially regulate resolution of inflammation and angiogenesis. During regression of new angiogenic capillaries, ghost vessels and empty basement membrane sleeves are formed, which can persist in the cornea for a long time. Here, ghost vessels were found to facilitate subsequent revascularization of the cornea, while empty basement membrane sleeves did not revascularize. The revascularization response observed here was characterised by vasodilation, increased inflammatory cell infiltration and by sprouting at the front of the reperfused vessels. Importantly, reactive oxygen species and nitrous oxide signaling among other pro-inflammatory pathways were activated, and at the same time anti-inflammatory LXR/RXR signaling was inhibited. The interplay between activation and inhibition of these pathways highlights potential mechanisms that regulate corneal revascularization. When treating corneal neovascularization clinically, corticosteroids are in widespread use due to their effectiveness. To minimize the many undesirable side effects associated with corticosteroid use, however, identifying new and more selective agents is of great importance. Here, it was observed that corticosteroids not only suppressed pro-inflammatory chemokines and cytokines, but also activated the classical complement pathway. Classical complement may represent a candidate for further selective therapeutic manipulation to investigate its effect on treatment of corneal neovascularization. In summary, this thesis identifies genes, pathways, and phenotypic responses involved in sprouting and remodeling of corneal capillaries, highlights novel pathways and factors that may regulate inflammation and angiogenesis in the cornea, and provides insights into regulation of capillary regression and reactivation. Further investigation of these regulatory mechanisms may offer alternative and effective treatment targets for the treatment of corneal inflammation and angiogenesis.
Book Synopsis Cornea and External Eye Disease by : Thomas Reinhard
Download or read book Cornea and External Eye Disease written by Thomas Reinhard and published by Springer Science & Business Media. This book was released on 2007-12-10 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: This outstanding volume in the Essentials in Ophthalmology series presents recent developments in the diagnosis and treatment of corneal disease. Its intention is not to replace the relevant textbooks, but to serve as a bridge between primary and tertiary literature. The superbly structured volume covers a dizzying array of topics including Herpes simplex keratitis; amniotic membrane transplantation for the treatment of corneal ulceration in infectious keratitis; and Chlamydial infection, all three of which are hugely relevant today. All the topics have direct clinical importance and will not only keep ophthalmologists up to date, but will inform them of how to treat their cornea patients with optimal diagnostic and therapeutic procedures.
Book Synopsis An Essay on the Ophthalmia Or Inflammation of the Eyes, and the Diseases of the Transparent Cornea by : William Rowley
Download or read book An Essay on the Ophthalmia Or Inflammation of the Eyes, and the Diseases of the Transparent Cornea written by William Rowley and published by . This book was released on 1771 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Publisher : ISBN 13 :0323058078 Total Pages : pages Book Rating :4.3/5 (23 download)
Book Synopsis Ocular Surface Disease: Cornea, Conjunctiva and Tear Film by : Edward J Holland
Download or read book Ocular Surface Disease: Cornea, Conjunctiva and Tear Film written by Edward J Holland and published by Elsevier Health Sciences. This book was released on 2013-05-17 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ocular Surface Disease: Cornea, Conjunctiva and Tear Film incorporates current research and the latest management strategies as well as classification systems and treatment paradigms for all forms of ocular surface disease. This is the first comprehensive resource that helps you to meet ocular surface disease challenges effectively using today's best medical and surgical approaches. Get the complete, evidence-based guidance you need to provide optimal care for your patients with ocular surface disease. Implement the latest drug treatments and surgical interventions to provide better outcomes with fewer complications. Hone and expand your surgical skills by watching videos of leading experts performing advanced procedures including ocular surface transplantation techniques; amniotic membrane transplantation; pterygium surgery; lamellar keratoplasty (DALK) in ocular surface disease; and keratoprosthesis surgery. Visualize how to proceed by reviewing detailed, full-color images and consulting new classification systems and treatment paradigms for mild to severe forms of ocular surface disease. Take it with you anywhere! Access the full text, downloadable image library, video clips, and more online at expertconsult.com.
Book Synopsis Infectious Eye Diseases by : Alejandro Rodriguez-Garcia
Download or read book Infectious Eye Diseases written by Alejandro Rodriguez-Garcia and published by BoD – Books on Demand. This book was released on 2021-10-27 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious eye disorders represent one of the most feared, sight-threatening, and challenging clinical ocular conditions. Visual loss due to eye infection significantly impacts patients’ productivity and quality of life. The development of accurate diagnostic tests and better treatment alternatives results from intensive and innovative medical research committed to improving the standard of care of patients suffering from these blinding diseases. This book focuses on the most recent advances in diagnostic techniques for common infectious disorders, including viral, fungal, and contact lens-related keratitis, infectious uveitis, endophthalmitis, and COVID-19-related eye infection. It also describes the current therapeutic strategies that significantly reduce the rate of ocular complications and improve the visual outcome of patients suffering from such devastating disorders.
Book Synopsis Roy and Fraunfelder's Current Ocular Therapy by : Frederick Hampton Roy
Download or read book Roy and Fraunfelder's Current Ocular Therapy written by Frederick Hampton Roy and published by Elsevier Health Sciences. This book was released on 2008-01-01 with total page 732 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to be concise with a consistent format so that the clinician can focus on a specific area. This edition has had major modifications and embraces evidence-based medicine. The format includes the CPT codes for billing purposes, short description of the condition, etiology/incidence, course/prognosis, laboratory findings, differential diagnosis; prophylaxis, treatment (local and systemic, surgical or other), miscellaneous (names and addresses of support groups) and key references. Incorporates evidence-based medicine so you feel confident that you're formulating the best treatment plans for your patients.Color photos allow you to read about and actually see a picture of select disease entities.Clear, concise format can be photocopied and distributed to patients in some cases, reducing your time spent explaining problems to patients and caregivers.
