Control And Surveillance Of Human African Trypanosomiasis

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Control and Surveillance of Human African Trypanosomiasis

Author : World Health Organization
Publisher : World Health Organization
ISBN 13 : 9241209844
Total Pages : 249 pages
Book Rating : 4.2/5 (412 download)

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Book Synopsis Control and Surveillance of Human African Trypanosomiasis by : World Health Organization

Download or read book Control and Surveillance of Human African Trypanosomiasis written by World Health Organization and published by World Health Organization. This book was released on 2013 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report provides information about new diagnostic approaches, new therapeutic regimens and better understanding of the distribution of the disease with high-quality mapping. The roles of human and animal reservoirs and the tsetse fly vectors that transmit the parasites are emphasized. The new information has formed the basis for an integrated strategy with which it is hoped that elimination of HAT will be achieved. The report also contains recommendations on the approaches that will lead to elimination of the disease. Human African Tryponosomiasis (HAT) is a disease that afflicts populations in rural Africa, where the tsetse fly vector that transmits the causative trypanosome parasites thrives. There are two forms of HAT: one, known as gambiense HAT, is endemic in West and Central Africa and causes over 95% of current cases; the other, known as rhodesiense HAT, is endemic in East and southern Africa and accounts for the remainder of cases. The presence of parasites in the brain leads to progressive neurological breakdown. Changes to sleep-wake patterns are among the symptoms that characterize the disease, also known as "sleeping sickness". Eventually, patients fall into a coma and die if not treated. Different treatments are available against parasites present in the haemolymphatic system (first stage) and those that have entered the brain (second stage). Currently, lumbar puncture is required to select the appropriate drug.

Control and Surveillance of Human African Trypanosomiasis

Author :
Publisher :
ISBN 13 :
Total Pages : 237 pages
Book Rating : 4.:/5 (871 download)

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Book Synopsis Control and Surveillance of Human African Trypanosomiasis by :

Download or read book Control and Surveillance of Human African Trypanosomiasis written by and published by . This book was released on 2013 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Control and Surveillance of African Trypanosomiasis

Author :
Publisher : World Health Organization
ISBN 13 : 9241208813
Total Pages : 121 pages
Book Rating : 4.2/5 (412 download)

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Book Synopsis Control and Surveillance of African Trypanosomiasis by :

Download or read book Control and Surveillance of African Trypanosomiasis written by and published by World Health Organization. This book was released on 1998 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contracting is a tool that is playing an increasing role in many health systems. Although contracting has the potential to add benefits to health systems it also adds further complexity. Following a substantial health sector reform and the introduction of a purchaser-provider split contracting became a central part of the management of New Zealand's publicly funded health system during the period 1993 to 2000. This publication examines a number of different aspects of New Zealand's experience of using contracts in the health sector including the contracting process contract content and form purchaser-provider relationships including sources of tension and factors that alleviated tensions and issues related to monitoring and accountability. This publication may assist other countries that are using or are planning to use contracts within their health systems.

WHO Interim Guidelines for the Treatment of Gambiense Human African Trypanosomiasis

Author : World Health Organization
Publisher :
ISBN 13 :
Total Pages : 44 pages
Book Rating : 4.:/5 (113 download)

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Book Synopsis WHO Interim Guidelines for the Treatment of Gambiense Human African Trypanosomiasis by : World Health Organization

Download or read book WHO Interim Guidelines for the Treatment of Gambiense Human African Trypanosomiasis written by World Health Organization and published by . This book was released on 2019 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human African trypanosomiasis (HAT), or sleeping sickness, is a parasitic infection that is almost invariably fatal unless treated. It is a neglected tropical disease that occurs in sub-Saharan Africa. The incidence of the disease is declining in response to intensive surveillance and control in endemic areas. As a result, HAT is among the neglected tropical diseases targeted by the World Health Organization (WHO) for elimination. WHO maintains exhaustive records of all declared cases; in 2018, a historically low number of cases (less than 1000) was reported. The remarkable progress in the control of gambiense HAT has relied on case-finding and curative treatment, a strategy that interrupts transmission by depleting the reservoir of parasites in humans. This has been combined occasionally with vector control activities. The subject of these guidelines, therefore, is of utmost importance for the continuation of progress to eliminate HAT. The recent approval of a new medicine (fexinidazole) for the treatment of gambiense HAT has opened new possibilities for the management of cases and thus warrants the new WHO recommendations contained herein. While studies of fexinidazole and other therapies are ongoing, these guidelines are considered interim guidelines until new information becomes available. This document focuses on the management of patients affected by gambiense HAT and constitutes an update to the WHO therapeutic guidance issued in 2013.

Epidemiology and Control of African Trypanosomiasis

Author : WHO Expert Committee on the Epidemiology and Control of African Trypanosomiasis
Publisher :
ISBN 13 :
Total Pages : 132 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Epidemiology and Control of African Trypanosomiasis by : WHO Expert Committee on the Epidemiology and Control of African Trypanosomiasis

Download or read book Epidemiology and Control of African Trypanosomiasis written by WHO Expert Committee on the Epidemiology and Control of African Trypanosomiasis and published by . This book was released on 1986 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Criteria and procedures for the verification of elimination of transmission of T. b. gambiense to the human population in a given country

Download Criteria and procedures for the verification of elimination of transmission of T. b. gambiense to the human population in a given country PDF Online Free

Author : World Health Organization
Publisher : World Health Organization
ISBN 13 : 9240075550
Total Pages : 44 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Criteria and procedures for the verification of elimination of transmission of T. b. gambiense to the human population in a given country by : World Health Organization

Download or read book Criteria and procedures for the verification of elimination of transmission of T. b. gambiense to the human population in a given country written by World Health Organization and published by World Health Organization. This book was released on 2023-11-06 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Human Emerging and Re-emerging Infections

Author : Sunit Kumar Singh
Publisher : John Wiley & Sons
ISBN 13 : 1118644646
Total Pages : 1072 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Human Emerging and Re-emerging Infections by : Sunit Kumar Singh

Download or read book Human Emerging and Re-emerging Infections written by Sunit Kumar Singh and published by John Wiley & Sons. This book was released on 2015-11-09 with total page 1072 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging and re-emerging pathogens pose several challenges to diagnosis, treatment, and public health surveillance, primarily because pathogen identification is a difficult and time-consuming process due to the “novel” nature of the agent. Proper identification requires a wide array of techniques, but the significance of these diagnostics is anticipated to increase with advances in newer molecular and nanobiotechnological interventions and health information technology. Human Emerging and Re-emerging Infections covers the epidemiology, pathogenesis, diagnostics, clinical features, and public health risks posed by new viral and microbial infections. The book includes detailed coverage on the molecular mechanisms of pathogenesis, development of various diagnostic tools, diagnostic assays and their limitations, key research priorities, and new technologies in infection diagnostics. Volume 1 addresses viral and parasitic infections, while volume 2 delves into bacterial and mycotic infections. Human Emerging and Re-emerging Infections is an invaluable resource for researchers in parasitologists, microbiology, Immunology, neurology and virology, as well as clinicians and students interested in understanding the current knowledge and future directions of infectious diseases.

Human African Trypanosomiasis (Sleeping Sickness)

Author : Christian Burri
Publisher : MDPI
ISBN 13 : 3039289632
Total Pages : 280 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Human African Trypanosomiasis (Sleeping Sickness) by : Christian Burri

Download or read book Human African Trypanosomiasis (Sleeping Sickness) written by Christian Burri and published by MDPI. This book was released on 2020-06-17 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: As it is a goal to eliminate human African trypanosomiasis (HAT; sleeping sickness) as a public health problem by 2020 and interrupt transmission by 2030, this is a good moment to reflect on what we have achieved, what we want to achieve, and what could get in our way. HAT has a reputation for spectacular reappearances, and the latest peak of 40,000 reported and over 300,000 estimated cases only dates back to 1998. Efforts of the WHO and partners as well as the development of simpler and much better-tolerated treatments, improved diagnostics, and vector control tools made it possible to reduce this number by 95%. Case identification and confirmation remain complex and require specific skills, treatment remains error-prone and reports on long-term survivors have emerged, and the relevance of the animal reservoir for T. b. gambiense HAT needs clarification. In addition, to win the “end game” against this massively stigmatized disease, the human factor will play a key role. This Special Issue addresses many of the burning topics about disease elimination in its 12 research and 7 review articles and one case study. The papers critically reflect the approaches used, investigate the mentioned challenges, and propose novel approaches and interventions from various points of view.

Report of the third WHO stakeholders meeting on gambiense human African trypanosomiasis elimination, Geneva, Switzerland, 18-20 April 2018

Download Report of the third WHO stakeholders meeting on gambiense human African trypanosomiasis elimination, Geneva, Switzerland, 18-20 April 2018 PDF Online Free

Author :
Publisher : World Health Organization
ISBN 13 : 9240002294
Total Pages : 74 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Report of the third WHO stakeholders meeting on gambiense human African trypanosomiasis elimination, Geneva, Switzerland, 18-20 April 2018 by :

Download or read book Report of the third WHO stakeholders meeting on gambiense human African trypanosomiasis elimination, Geneva, Switzerland, 18-20 April 2018 written by and published by World Health Organization. This book was released on 2020-03-30 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Trypanosomes and Trypanosomiasis

Author : Stefan Magez
Publisher : Springer Science & Business Media
ISBN 13 : 3709115566
Total Pages : 300 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Trypanosomes and Trypanosomiasis by : Stefan Magez

Download or read book Trypanosomes and Trypanosomiasis written by Stefan Magez and published by Springer Science & Business Media. This book was released on 2013-09-24 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume written by experts in the field of trypanosome research covers every aspect of trypanosome-vector-host biology. It is a must read for basic researchers working with trypanosomes and related organisms, infection and drug development as well as parasitology in a broader sense.

The Trypanosomiases

Author : Ian Maudlin
Publisher : CABI
ISBN 13 : 9780851990347
Total Pages : 644 pages
Book Rating : 4.9/5 (93 download)

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Book Synopsis The Trypanosomiases by : Ian Maudlin

Download or read book The Trypanosomiases written by Ian Maudlin and published by CABI. This book was released on 2004-07-09 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: This state-of-the-art reference book includes comprehensive coverage of the biology and control of African, Asian and South American trypanosomiasis ("sleeping sickness") in man and animals. It describes recent research developments in the biology and molecular biology of trypanosomes (the protozoan parasite) and their vectors, and methods in diagnosis and control, such as trapping tsetse fly vectors. Different sections of the book are devoted to biology of trypanosomes, vector biology, epidemiology and diagnosis, pathogenesis, disease impact, chemotherapy and disease control, and vector control. The book contains contributions from leading experts from Europe, North and South America, and Africa.

Progress in Human African Trypanosomiasis, Sleeping Sickness

Author : Michel Dumas
Publisher : Springer Science & Business Media
ISBN 13 : 2817808576
Total Pages : 347 pages
Book Rating : 4.8/5 (178 download)

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Book Synopsis Progress in Human African Trypanosomiasis, Sleeping Sickness by : Michel Dumas

Download or read book Progress in Human African Trypanosomiasis, Sleeping Sickness written by Michel Dumas and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human African Trypaniosomiasis (HAT) or sleeping sickness is an old disease to be now considered as reemergent. HAT is endemic in 36 sub-Saharan African countries, in areas where tsetse flies are found. The public health importance of HAT is underestimated, but the disease causes severe social disruption in many rural areas. Along the past fifteen years, numerous studies were made, and now, the mechanisms involved in the disease pathogenesis and in the characteristics of sleep-wake disruption become to be better understood. But, since 50 years, when current drugs were introduced, problems regarding HAT chemotherapy have not been solved. Nevertheless, in-depth studies about trypanosome metabolism have permitted to discover new drug targets. Written by specialists who are very experienced in their respective fields, the contributions provide an indispensable tool for practitioners and scientists.

Investing to Overcome the Global Impact of Neglected Tropical Diseases

Author : World Health Organization
Publisher : World Health Organization
ISBN 13 : 9241564865
Total Pages : 211 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Investing to Overcome the Global Impact of Neglected Tropical Diseases by : World Health Organization

Download or read book Investing to Overcome the Global Impact of Neglected Tropical Diseases written by World Health Organization and published by World Health Organization. This book was released on 2015-08-05 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The presence, or absence, of neglected tropical diseases (NTDs) can be seen as a proxy for poverty and for the success of interventions aimed at reducing poverty. Today, coverage of the public-health interventions recommended by the World Health Organization (WHO) against NTDs may be interpreted as a proxy for universal health coverage and shared prosperity - in short, a proxy for coverage against neglect. As the world's focus shifts from development to sustainable development, from poverty eradication to shared prosperity, and from disease-specific goals to universal health coverage, control of NTDs will assume an important role towards the target of achieving universal health coverage, including individual financial risk protection. Success in overcoming NTDs is a "litmus test" for universal health coverage against NTDs in endemic countries. The first WHO report on NTDs (2010) set the scene by presenting the evidence for how these interventions had produced results. The second report (2013) assessed the progress made in deploying them and detailed the obstacles to their implementation. This third report analyses for the first time the investments needed to achieve the scale up of implementation required to achieve the targets of the WHO Roadmap on NTDs and universal coverage against NTDs. INVESTING TO OVERCOME THE GLOBAL IMPACT OF NEGLECTED TROPICAL DISEASES presents an investment strategy for NTDs and analyses the specific investment case for prevention, control, elimination and eradication of 12 of the 17 NTDs. Such an analysis is justified following the adoption by the Sixty-sixth World Health Assembly in 2013 of resolution WHA6612 on neglected tropical diseases, which called for sufficient and predictable funding to achieve the Roadmap's targets and sustain control efforts. The report cautions, however, that it is wise investment and not investment alone that will yield success. The report registers progress and challenges and signals those that lie ahead. Climate change is expected to increase the spread of several vector-borne NTDs, notably dengue, transmission of which is directly influenced by temperature, rainfall, relative humidity and climate variability primarily through their effects on the vector. Investments in vector-borne diseases will avoid the potentially catastrophic expenditures associated with their control. The presence of NTDs will thereby signal an early warning system for climate-sensitive diseases. The ultimate goal is to deliver enhanced and equitable interventions to the most marginalized populations in the context of a changing public-health and investment landscape to ensure that all peoples affected by NTDs have an opportunity to lead healthier and wealthier lives."--Publisher's description.

Revolutionizing Tropical Medicine

Author : Kerry Atkinson
Publisher : John Wiley & Sons
ISBN 13 : 1119282659
Total Pages : 768 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis Revolutionizing Tropical Medicine by : Kerry Atkinson

Download or read book Revolutionizing Tropical Medicine written by Kerry Atkinson and published by John Wiley & Sons. This book was released on 2019-05-23 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive resource describing innovative technologies and digital health tools that can revolutionize the delivery of health care in low- to middle-income countries, particularly in remote rural impoverished communities Revolutionizing Tropical Medicine offers an up-to-date guide for healthcare and other professionals working in low-resource countries where access to health care facilities for diagnosis and treatment is challenging. Rather than suggesting the expensive solution of building new bricks and mortar clinics and hospitals and increasing the number of doctors and nurses in these deprived areas, the authors propose a complete change of mindset. They outline a number of ideas for improving healthcare including rapid diagnostic testing for infectious and non-infectious diseases at a point-of-care facility, together with low cost portable imaging devices. In addition, the authors recommend a change in the way in which health care is delivered. This approach requires task-shifting within the healthcare provision system so that nurses, laboratory technicians, pharmacists and others are trained in the newly available technologies, thus enabling faster and more appropriate triage for people requiring medical treatment. This text: Describes the current burden of communicable and non-communicable diseases in low- to middle-income countries throughout the world Describes the major advances in healthcare outcomes in low-to middle-income countries derived from implementation of the United Nations/World Health Organisation’s 2000 Millennium Development Goals Provides a review of inexpensive rapid diagnostic point-of-care tests for infectious diseases in low-resource countries, particularly for people living in remote rural areas Provides a review of other rapid point-of-care services for assessing hematological function, biochemical function, renal function, hepatic function and status including hepatitis, acid-base balance, sickle cell disease, severe acute malnutrition and spirometry Explores the use of low-cost portable imaging devices for use in remote rural areas including a novel method of examining the optic fundus using a smartphone and the extensive value of portable ultrasound scanning when x-ray facilities are not available Describes the use of telemedicine in the clinical management of both children and adults in remote rural settings Looks to the future of clinical management in remote impoverished rural settings using nucleic acid identification of pathogens, the use of nanoparticles for water purification, the use of drones, the use of pulse oximetry and the use of near-infrared spectroscopy Finally, it assesses the potential for future healthcare improvement in impoverished areas and how the United Nations/World Health Organization 2015 Sustainable Development Goals are approaching this. Written for physicians, infectious disease specialists, pathologists, radiologists, nurses, pharmacists and other health care workers, as well as government healthcare managers, Revolutionizing Tropical Medicine is a new up-to-date essential and realistic guide to treating and diagnosing patients in low-resource tropical countries based on new technologies.

One Health, 2nd Edition

Author : Jakob Zinsstag
Publisher : CABI
ISBN 13 : 1789242576
Total Pages : 459 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis One Health, 2nd Edition by : Jakob Zinsstag

Download or read book One Health, 2nd Edition written by Jakob Zinsstag and published by CABI. This book was released on 2020-09-30 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: One Health, the concept of combined veterinary and human health, has now expanded beyond emerging infectious diseases and zoonoses to incorporate a wider suite of health issues. Retaining its interdisciplinary focus which combines theory with practice, this new edition illustrates the contribution of One Health collaborations to real-world issues such as sanitation, economics, food security and vaccination programmes. It includes more non-infectious disease issues and climate change discussion alongside revised case studies and expanded methodology chapters to draw out implications for practice. Promoting an action-based, solutions-oriented approach, One Health: The Theory and Practice of Integrated Health Approaches highlights the lessons learned for both human and animal health professionals and students.

The African Trypanosomes

Author : Samuel J. Black
Publisher : Springer Science & Business Media
ISBN 13 : 0306468948
Total Pages : 185 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis The African Trypanosomes by : Samuel J. Black

Download or read book The African Trypanosomes written by Samuel J. Black and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: African trypanosomes are tsetse-transmitted protozoa that inhabit the extracellular compartment of host blood. They cause fatal sleeping sickness in people, and Nagana, a wasting and generally fatal disease, in cattle. While trypanosomes are most common to Africa (about 30% of Africa's cattle graze on the fringe of the tsetse habitat), some species have spread beyond its boarders to Asia, the Middle East and South America. The African Trypanosomes, volume one of World Class Parasites, is written for researchers, students and scholars who enjoy reading research that has a major impact on human health, or agricultural productivity, and against which we have no satisfactory defense. It is intended to supplement more formal texts that cover taxonomy, life cycles, morphology, vector distribution, symptoms and treatment. It integrates vector, pathogen and host biology and celebrates the diversity of approach that comprises modern parasitological research.

African Trypanosomiasis

Author : Gerald T. Hughes
Publisher : Nova Science Publishers
ISBN 13 : 9781634847124
Total Pages : 0 pages
Book Rating : 4.8/5 (471 download)

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Book Synopsis African Trypanosomiasis by : Gerald T. Hughes

Download or read book African Trypanosomiasis written by Gerald T. Hughes and published by Nova Science Publishers. This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human African trypanosomiasis or sleeping sickness is caused by infection with the morphologically indistinguishable subspecies Trypanosoma brucei rhodesiense (in East and Southern Africa) and Trypanosoma brucei gambiense (in West and Central Africa). The disease is presently almost under control and less than 4000 cases are currently reported. In both, T. b. rhodesiense and T. b. gambiense infection, after the injection of infective metacyclic trypanosomes with tsetse fly vector saliva, the parasites establish in the skin, differentiate to the bloodstream stage and spread via the local draining lymph node into the vascular system. In this book, Chapter One presents an overview of the current epidemiology, clinical features, diagnosis and treatment options. Chapter Two provides an in-depth review of diagnostic methods for African trypanosomiasis. Chapter Three discusses the use of aminoadamantane derivatives against Trypanosoma brucei.