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Computational Phenotypes
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Book Synopsis Computational Phenotypes by : Sergio Balari
Download or read book Computational Phenotypes written by Sergio Balari and published by Oxford University Press. This book was released on 2013 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a book about language as a species-typical trait of humans. It argues that language is not so exceptional after all, as according to the authors it is just the human version of a rather common and conservative organic system that they refer to as the Central Computational Complex.
Book Synopsis Phenotypes and Genotypes by : Florian Frommlet
Download or read book Phenotypes and Genotypes written by Florian Frommlet and published by Springer. This book was released on 2016-02-12 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely text presents a comprehensive guide to genetic association, a new and rapidly expanding field that aims to elucidate how our genetic code (genotypes) influences the traits we possess (phenotypes). The book provides a detailed review of methods of gene mapping used in association with experimental crosses, as well as genome-wide association studies. Emphasis is placed on model selection procedures for analyzing data from large-scale genome scans based on specifically designed modifications of the Bayesian information criterion. Features: presents a thorough introduction to the theoretical background to studies of genetic association (both genetic and statistical); reviews the latest advances in the field; illustrates the properties of methods for mapping quantitative trait loci using computer simulations and the analysis of real data; discusses open challenges; includes an extensive statistical appendix as a reference for those who are not totally familiar with the fundamentals of statistics.
Book Synopsis Computational Psychiatry by : A. David Redish
Download or read book Computational Psychiatry written by A. David Redish and published by MIT Press. This book was released on 2016-12-09 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychiatrists and neuroscientists discuss the potential of computational approaches to address problems in psychiatry including diagnosis, treatment, and integration with neurobiology. Modern psychiatry is at a crossroads, as it attempts to balance neurological analysis with psychological assessment. Computational neuroscience offers a new lens through which to view such thorny issues as diagnosis, treatment, and integration with neurobiology. In this volume, psychiatrists and theoretical and computational neuroscientists consider the potential of computational approaches to psychiatric issues. This unique collaboration yields surprising results, innovative synergies, and novel open questions. The contributors consider mechanisms of psychiatric disorders, the use of computation and imaging to model psychiatric disorders, ways that computation can inform psychiatric nosology, and specific applications of the computational approach. Contributors Susanne E. Ahmari, Huda Akil, Deanna M. Barch, Matthew Botvinick, Michael Breakspear, Cameron S. Carter, Matthew V. Chafee, Sophie Denève, Daniel Durstewitz, Michael B. First, Shelly B. Flagel, Michael J. Frank, Karl J. Friston, Joshua A. Gordon, Katia M. Harlé, Crane Huang, Quentin J. M. Huys, Peter W. Kalivas, John H. Krystal, Zeb Kurth-Nelson, Angus W. MacDonald III, Tiago V. Maia, Robert C. Malenka, Sanjay J. Mathew, Christoph Mathys, P. Read Montague, Rosalyn Moran, Theoden I. Netoff, Yael Niv, John P. O'Doherty, Wolfgang M. Pauli, Martin P. Paulus, Frederike Petzschner, Daniel S. Pine, A. David Redish, Kerry Ressler, Katharina Schmack, Jordan W. Smoller, Klaas Enno Stephan, Anita Thapar, Heike Tost, Nelson Totah, Jennifer L. Zick
Book Synopsis Multi-omics and computational biology in horticultural plants: From genotype to phenotype by : Yunpeng Cao
Download or read book Multi-omics and computational biology in horticultural plants: From genotype to phenotype written by Yunpeng Cao and published by Frontiers Media SA. This book was released on 2023-02-28 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Computational Theory of Mind by : Matteo Colombo
Download or read book The Computational Theory of Mind written by Matteo Colombo and published by Cambridge University Press. This book was released on 2023-11-29 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Computational Theory of Mind says that the mind is a computing system. It has a long history going back to the idea that thought is a kind of computation. Its modern incarnation relies on analogies with contemporary computing technology and the use of computational models. It comes in many versions, some more plausible than others. This Element supports the theory primarily by its contribution to solving the mind-body problem, its ability to explain mental phenomena, and the success of computational modelling and artificial intelligence. To be turned into an adequate theory, it needs to be made compatible with the tractability of cognition, the situatedness and dynamical aspects of the mind, the way the brain works, intentionality, and consciousness.
Book Synopsis Research in Computational Molecular Biology by : Terry Speed
Download or read book Research in Computational Molecular Biology written by Terry Speed and published by Springer. This book was released on 2007-05-18 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 11th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2007, held in Oakland, CA, USA in April 2007. The 37 revised full papers address all current issues in algorithmic, theoretical, and experimental bioinformatics.
Download or read book Phenotypes and Endophenotypes written by and published by . This book was released on 2009 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Systems Genetics by : Florian Markowetz
Download or read book Systems Genetics written by Florian Markowetz and published by Cambridge University Press. This book was released on 2015-07-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whereas genetic studies have traditionally focused on explaining heritance of single traits and their phenotypes, recent technological advances have made it possible to comprehensively dissect the genetic architecture of complex traits and quantify how genes interact to shape phenotypes. This exciting new area has been termed systems genetics and is born out of a synthesis of multiple fields, integrating a range of approaches and exploiting our increased ability to obtain quantitative and detailed measurements on a broad spectrum of phenotypes. Gathering the contributions of leading scientists, both computational and experimental, this book shows how experimental perturbations can help us to understand the link between genotype and phenotype. A snapshot of current research activity and state-of-the-art approaches to systems genetics are provided, including work from model organisms such as Saccharomyces cerevisiae and Drosophila melanogaster, as well as from human studies.
Book Synopsis Computational Systems Biology by : Andres Kriete
Download or read book Computational Systems Biology written by Andres Kriete and published by Academic Press. This book was released on 2013-11-26 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling. Logical information flow aids understanding of basic building blocks of life through disease phenotypes Evolved principles gives insight into underlying organizational principles of biological organizations, and systems processes, governing functions such as adaptation or response patterns Coverage of technical tools and systems helps researchers to understand and resolve specific systems biology problems using advanced computation Multi-scale modeling on disparate scales aids researchers understanding of dependencies and constraints of spatio-temporal relationships fundamental to biological organization and function.
Book Synopsis Intelligent Image Analysis for Plant Phenotyping by : Ashok Samal
Download or read book Intelligent Image Analysis for Plant Phenotyping written by Ashok Samal and published by CRC Press. This book was released on 2020-10-21 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Domesticated crops are the result of artificial selection for particular phenotypes or, in some cases, natural selection for an adaptive trait. Plant traits can be identified through image-based plant phenotyping, a process that was, until recently, strenous and time-consuming. Intelligent Image Analysis for Plant Phenotyping reviews information on time-saving techniques, using computer vision and imaging technologies. These methodologies provide an automated, non-invasive, and scalable mechanism by which to define and collect plant phenotypes. Beautifully illustrated, with numerous color images, the book focuses on phenotypes measured from individual plants under controlled experimental conditions, which are widely available in high-throughput systems. Features: Presents methodologies for image processing, including data-driven and machine learning techniques for plant phenotyping. Features information on advanced techniques for extracting phenotypes through images and image sequences captured in a variety of modalities. Includes real-world scientific problems, including predicting yield by modeling interactions between plant data and environmental information. Discusses the challenge of translating images into biologically informative quantitative phenotypes. A practical resource for students, researchers, and practitioners, this book is invaluable for those working in the emerging fields at the intersection of computer vision and plant sciences.
Book Synopsis Linking Phenotypes and Genotypes by : Florian Markowetz
Download or read book Linking Phenotypes and Genotypes written by Florian Markowetz and published by Cambridge University Press. This book was released on 2015-07-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to comprehensively cover the field of systems genetics, gathering contributions from leading scientists.
Book Synopsis Leveraging Data Science for Global Health by : Leo Anthony Celi
Download or read book Leveraging Data Science for Global Health written by Leo Anthony Celi and published by Springer Nature. This book was released on 2020-07-31 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book explores ways to leverage information technology and machine learning to combat disease and promote health, especially in resource-constrained settings. It focuses on digital disease surveillance through the application of machine learning to non-traditional data sources. Developing countries are uniquely prone to large-scale emerging infectious disease outbreaks due to disruption of ecosystems, civil unrest, and poor healthcare infrastructure – and without comprehensive surveillance, delays in outbreak identification, resource deployment, and case management can be catastrophic. In combination with context-informed analytics, students will learn how non-traditional digital disease data sources – including news media, social media, Google Trends, and Google Street View – can fill critical knowledge gaps and help inform on-the-ground decision-making when formal surveillance systems are insufficient.
Download or read book Beyond the DSM written by Steven C. Hayes and published by New Harbinger Publications. This book was released on 2020-10-01 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a mental health clinician, you know that every client is unique, and a client’s symptoms are the result of a complex combination of psychological, environmental, genetic, and neural factors. However, the de facto DSM model poses considerable constraints on how you can treat clients—often resulting in a one-size-fits-all diagnosis. This important volume challenges the assumptions and approach made by the DSM, and provides a vision and plan for an evidence-based, process-based approach to individualized care. With contributions from renowned experts in the field—including Steven C. Hayes, Stefan G. Hofmann, Joseph Ciarrochi, Matthew McKay, Uma Vaidyanathan, Sarah Morris, David Sommers, J. Scott Fraser, and many more—this groundbreaking book will show you a new way to recognize the complexity of human suffering and human prosperity. You’ll find solid tips for treating a wide variety of psychological issues in a more flexible way. And, finally, you’ll come away with a greater understanding of the “processes of change,” and how to build a solid foundation for an alternative to syndromal diagnosis. The future of mental health treatment is process-based. Whether you’re a clinician, researcher, student, instructor, or other professional working in the mental health field, this breakthrough volume offers everything you need to understand process-based treatment and create a more customized and effective approach to treating clients.
Book Synopsis Computational Complexity and Statistical Physics by : Allon Percus
Download or read book Computational Complexity and Statistical Physics written by Allon Percus and published by Oxford University Press. This book was released on 2006-02-23 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computer science and physics have been closely linked since the birth of modern computing. In recent years, an interdisciplinary area has blossomed at the junction of these fields, connecting insights from statistical physics with basic computational challenges. Researchers have successfully applied techniques from the study of phase transitions to analyze NP-complete problems such as satisfiability and graph coloring. This is leading to a new understanding of the structure of these problems, and of how algorithms perform on them. Computational Complexity and Statistical Physics will serve as a standard reference and pedagogical aid to statistical physics methods in computer science, with a particular focus on phase transitions in combinatorial problems. Addressed to a broad range of readers, the book includes substantial background material along with current research by leading computer scientists, mathematicians, and physicists. It will prepare students and researchers from all of these fields to contribute to this exciting area.
Book Synopsis Phenotyping; From Plant, to Data, to Impact and Highlights of the The International Plant Phenotyping Symposium - IPPS 2018 by : Trevor Garnett
Download or read book Phenotyping; From Plant, to Data, to Impact and Highlights of the The International Plant Phenotyping Symposium - IPPS 2018 written by Trevor Garnett and published by Frontiers Media SA. This book was released on 2021-01-19 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Data Driven Approaches for Healthcare by : Chengliang Yang
Download or read book Data Driven Approaches for Healthcare written by Chengliang Yang and published by CRC Press. This book was released on 2019-10-01 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt: Health care utilization routinely generates vast amounts of data from sources ranging from electronic medical records, insurance claims, vital signs, and patient-reported outcomes. Predicting health outcomes using data modeling approaches is an emerging field that can reveal important insights into disproportionate spending patterns. This book presents data driven methods, especially machine learning, for understanding and approaching the high utilizers problem, using the example of a large public insurance program. It describes important goals for data driven approaches from different aspects of the high utilizer problem, and identifies challenges uniquely posed by this problem. Key Features: Introduces basic elements of health care data, especially for administrative claims data, including disease code, procedure codes, and drug codes Provides tailored supervised and unsupervised machine learning approaches for understanding and predicting the high utilizers Presents descriptive data driven methods for the high utilizer population Identifies a best-fitting linear and tree-based regression model to account for patients’ acute and chronic condition loads and demographic characteristics
Book Synopsis The Potential Impact of High-End Capability Computing on Four Illustrative Fields of Science and Engineering by : National Research Council
Download or read book The Potential Impact of High-End Capability Computing on Four Illustrative Fields of Science and Engineering written by National Research Council and published by National Academies Press. This book was released on 2008-10-28 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many federal funding requests for more advanced computer resources assume implicitly that greater computing power creates opportunities for advancement in science and engineering. This has often been a good assumption. Given stringent pressures on the federal budget, the White House Office of Management and Budget (OMB) and Office of Science and Technology Policy (OSTP) are seeking an improved approach to the formulation and review of requests from the agencies for new computing funds. This book examines, for four illustrative fields of science and engineering, how one can start with an understanding of their major challenges and discern how progress against those challenges depends on high-end capability computing (HECC). The four fields covered are: atmospheric science astrophysics chemical separations evolutionary biology This book finds that all four of these fields are critically dependent on HECC, but in different ways. The book characterizes the components that combine to enable new advances in computational science and engineering and identifies aspects that apply to multiple fields.
