Computational Methods in Cardiac Electrophysiology

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832529259
Total Pages : 229 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Computational Methods in Cardiac Electrophysiology by : Matthijs Cluitmans

Download or read book Computational Methods in Cardiac Electrophysiology written by Matthijs Cluitmans and published by Frontiers Media SA. This book was released on 2023-07-06 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cardiac Electrophysiology Methods and Models

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1441966587
Total Pages : 490 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Cardiac Electrophysiology Methods and Models by : Daniel C. Sigg

Download or read book Cardiac Electrophysiology Methods and Models written by Daniel C. Sigg and published by Springer Science & Business Media. This book was released on 2010-09-11 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular disease is the major cause of mortality and morbidity in the Western Hemisphere. While significant progress has been made in treating a major sub-category of cardiac disease, arrhythmias, significant unmet needs remain. In particular, every day, thousands of patients die because of arrhythmias in the US alone, and atrial fibrillation is the most common arrhythmia affecting millions of patients in the US alone at a given time. Therefore, there is a public need to continue to develop new and better therapies for arrhythmias. Accordingly, an ever increasing number of biomedical, pharmaceutical, and medical personnel is interested in studying various aspects of arrhythmias at a basic, translational, and applied level, both in industry (ie Biotech, Pharmaceutical and device), and in academia. Not only has our overall understanding of molecular bases of disease dramatically increased, but so has the number of available and emerging molecular, pharmacological or device treatment based therapies. This practical, state-of-the art handbook will summarize and review key research methods and protocols, their advantages and pitfalls, with a focus on practical implementation, and collaborative cross-functional research. The volume will include visual and easy-to-use graphics, bulleted summaries, boxed summary paragraphs, links to reference websites, equipment manufacturers where appropriate, photographs of typical experimental setups and so forth, to keep this book very focused on practical methods and implementation, and yet, provide enough theory that the principles are clearly understood and can be easily applied.

Computational Cardiology

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Author :
Publisher : Springer
ISBN 13 : 3540259260
Total Pages : 364 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Computational Cardiology by : Frank B. Sachse

Download or read book Computational Cardiology written by Frank B. Sachse and published by Springer. This book was released on 2005-01-12 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to computer-based modeling in cardiology, by taking an educational point of view, and by summarizing knowledge from several, commonly considered delimited areas of cardiac research in a consistent way. First, the foundations and numerical techniques from mathematics are provided, with a particular focus on the finite element and finite differences methods. Then, the theory of electric fields and continuum mechanics is introduced with respect to numerical calculations in anisotropic biological media. In addition to the presentation of digital image processing techniques, the following chapters deal with particular aspects of cardiac modeling: cardiac anatomy, cardiac electro physiology, cardiac mechanics, modeling of cardiac electro mechanics. This book was written for researchers in modeling and cardiology, for clinical cardiologists, and for advanced students.

Mathematical Cardiac Electrophysiology

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Author :
Publisher : Springer
ISBN 13 : 3319048015
Total Pages : 410 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Mathematical Cardiac Electrophysiology by : Piero Colli Franzone

Download or read book Mathematical Cardiac Electrophysiology written by Piero Colli Franzone and published by Springer. This book was released on 2014-10-30 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the main mathematical and numerical models in computational electrocardiology, ranging from microscopic membrane models of cardiac ionic channels to macroscopic bidomain, monodomain, eikonal models and cardiac source representations. These advanced multiscale and nonlinear models describe the cardiac bioelectrical activity from the cell level to the body surface and are employed in both the direct and inverse problems of electrocardiology. The book also covers advanced numerical techniques needed to efficiently carry out large-scale cardiac simulations, including time and space discretizations, decoupling and operator splitting techniques, parallel finite element solvers. These techniques are employed in 3D cardiac simulations illustrating the excitation mechanisms, the anisotropic effects on excitation and repolarization wavefronts, the morphology of electrograms in normal and pathological tissue and some reentry phenomena. The overall aim of the book is to present rigorously the mathematical and numerical foundations of computational electrocardiology, illustrating the current research developments in this fast-growing field lying at the intersection of mathematical physiology, bioengineering and computational biomedicine. This book is addressed to graduate student and researchers in the field of applied mathematics, scientific computing, bioengineering, electrophysiology and cardiology.

Introduction to Computational Cardiology

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Publisher : Springer Science & Business Media
ISBN 13 : 0387766863
Total Pages : 236 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Introduction to Computational Cardiology by : Boris Ja. Kogan

Download or read book Introduction to Computational Cardiology written by Boris Ja. Kogan and published by Springer Science & Business Media. This book was released on 2009-12-09 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Computational Cardiology provides a comprehensive, in-depth treatment of the fundamental concepts and research challenges involved in the mathematical modeling and computer simulation of dynamical processes in the heart, under normal and pathological conditions. About this textbook: - Presents descriptions of models used in both biology and medicine for discovering the mechanisms of heart function and dysfunction on several physiological scales across different species. - Provides several examples throughout the textbook and exercises at the end which facilitate understanding of basic concepts and introduces, for implementation, treated problems to parallel supercomputers. Introduction to Computational Cardiology serves as a secondary textbook or reference book for advanced-level students in computer science, electrical engineering, biomedical engineering, and cardiac electrophysiology. It is also suitable for researchers employing mathematical modeling and computer simulations of biomedical problems.

Functional Imaging and Modeling of the Heart

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Author :
Publisher : Springer
ISBN 13 : 3540729070
Total Pages : 488 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Functional Imaging and Modeling of the Heart by : Frank B. Sachse

Download or read book Functional Imaging and Modeling of the Heart written by Frank B. Sachse and published by Springer. This book was released on 2007-07-10 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 4th International Conference on Functional Imaging and Modeling of the Heart, FIMH 2007, held in Salt Lake City, UT, USA in June 2007. The contributions describe both experimental and computational studies and cover topics such as imaging and image analysis, cardiac electrophysiology, electro- and magnetocardiography, cardiac mechanics and clinical application, imaging and anatomical modeling.

Computational Cardiology: Modelling of Anatomy, Electrophysiology and Mechanics

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Author :
Publisher :
ISBN 13 : 9781280307362
Total Pages : 322 pages
Book Rating : 4.3/5 (73 download)

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Book Synopsis Computational Cardiology: Modelling of Anatomy, Electrophysiology and Mechanics by : Frank B. Sachse

Download or read book Computational Cardiology: Modelling of Anatomy, Electrophysiology and Mechanics written by Frank B. Sachse and published by . This book was released on 2005 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to computer-based modeling in cardiology, by taking an educational point of view, and by summarizing knowledge from several, commonly considered delimited areas of cardiac research in a consistent way.First, the foundations and numerical techniques from mathematics are provided, with a particular focus on the finite element and finite differences methods. Then, the theory of electric fields and continuum mechanics is introduced with respect to numerical calculations in anisotropic biological media. In addition to the presentation of digital image processing techniques, the following chapters deal with particular aspects of cardiac modeling: cardiac anatomy, cardiac electro physiology, cardiac mechanics, modeling of cardiac electro mechanics.This book was written for researchers in modeling and cardiology, for clinical cardiologists, and for advanced students.

Computing the Electrical Activity in the Heart

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Publisher : Springer Science & Business Media
ISBN 13 : 3540334378
Total Pages : 323 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Computing the Electrical Activity in the Heart by : Joakim Sundnes

Download or read book Computing the Electrical Activity in the Heart written by Joakim Sundnes and published by Springer Science & Business Media. This book was released on 2007-06-26 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes mathematical models and numerical techniques for simulating the electrical activity in the heart. It gives an introduction to the most important models, followed by a detailed description of numerical techniques. Particular focus is on efficient numerical methods for large scale simulations on both scalar and parallel computers. The results presented in the book will be of particular interest to researchers in bioengineering and computational biology.

Exploring Mechanisms of Cardiac Rhythm Disturbances Using Novel Computational Methods: Prediction, Classification, and Therapy

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832517587
Total Pages : 232 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Exploring Mechanisms of Cardiac Rhythm Disturbances Using Novel Computational Methods: Prediction, Classification, and Therapy by : Xin Li

Download or read book Exploring Mechanisms of Cardiac Rhythm Disturbances Using Novel Computational Methods: Prediction, Classification, and Therapy written by Xin Li and published by Frontiers Media SA. This book was released on 2023-03-16 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Time-Stepping Methods in Cardiac Electrophysiology

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (13 download)

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Book Synopsis Time-Stepping Methods in Cardiac Electrophysiology by : Thomas Roy

Download or read book Time-Stepping Methods in Cardiac Electrophysiology written by Thomas Roy and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Computational And Mathematical Methods In Cardiovascular Physiology

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Publisher : World Scientific
ISBN 13 : 9813270659
Total Pages : 458 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis Computational And Mathematical Methods In Cardiovascular Physiology by : Liang Zhong

Download or read book Computational And Mathematical Methods In Cardiovascular Physiology written by Liang Zhong and published by World Scientific. This book was released on 2019-04-26 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular diseases (CVD) including heart diseases, peripheral vascular disease and heart failure, account for one-third of deaths throughout the world. CVD risk factors include systolic blood pressure, total cholesterol, high-density lipoprotein cholesterol, and diabetic status. Clinical trials have demonstrated that when modifiable risk factors are treated and corrected, the chances of CVD occurring can be reduced. This illustrates the importance of this book's elaborate coverage of cardiovascular physiology by the application of mathematical and computational methods.This book has literally transformed Cardiovascular Physiology into a STEM discipline, involving (i) quantitative formulations of heart anatomy and physiology, (ii) technologies for imaging the heart and blood vessels, (iii) coronary stenosis hemodynamics measure by means of fractional flow reserve and intervention by grafting and stenting, (iv) fluid mechanics and computational analysis of blood flow in the heart, aorta and coronary arteries, and (v) design of heart valves, percutaneous valve stents, and ventricular assist devices.So how is this mathematically and computationally configured landscape going to impact cardiology and even cardiac surgery? We are now entering a new era of mathematical formulations of anatomy and physiology, leading to technological formulations of medical and surgical procedures towards more precise medicine and surgery. This will entail reformatting of (i) the medical MD curriculum and courses, so as to educate and train a new generation of physicians who are conversant with medical technologies for applying into clinical care, as well as (ii) structuring of MD-PhD (Computational Medicine and Surgery) Program, to train competent medical and surgical specialists in precision medical care and patient-specific surgical care.This book provides a gateway for this new emerging scenario of (i) science and engineering based medical educational curriculum, and (ii) technologically oriented medical and surgical procedures. As such, this book can be usefully employed as a textbook for courses in (i) cardiovascular physiology in both the schools of engineering and medicine of universities, as well as (ii) cardiovascular engineering in biomedical engineering departments worldwide.

Computational Methods in Systems Biology

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Author :
Publisher : Springer Nature
ISBN 13 : 3031426975
Total Pages : 287 pages
Book Rating : 4.0/5 (314 download)

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Book Synopsis Computational Methods in Systems Biology by : Jun Pang

Download or read book Computational Methods in Systems Biology written by Jun Pang and published by Springer Nature. This book was released on with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Understanding Clinical Cardiac Electrophysiology

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118905490
Total Pages : 133 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Understanding Clinical Cardiac Electrophysiology by : Peter Spector

Download or read book Understanding Clinical Cardiac Electrophysiology written by Peter Spector and published by John Wiley & Sons. This book was released on 2016-05-16 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the fast paced world of clinical training, students are often inundated with the what of electrophysiology without the why. This new text is designed to tell the story of electrophysiology so that the seemingly disparate myriad observations of clinical practice come into focus as a cohesive and predictable whole. Presents a unique, conceptually-guided approach to understanding the movement of electrical current through the heart, the impact of various disease states and the positive effect of treatment Reviews electrophysiologic principles and the analytic tools which, when combined with a firm grasp of EP mechanisms, allow the reader to think through any situation Presents the mathematics necessary for the practice of cardiac electrophysiology in an accessible and understandable manner Contains accompanying video clips, including computer simulations showing the flow of electrical current through the heart, which help explain and visualise concepts discussed in the text Includes helpful chapter summaries and full color illustrations aid comprehension

Mathematical Cardiac Electrophysiology

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Author :
Publisher : Springer
ISBN 13 : 9783319048024
Total Pages : 397 pages
Book Rating : 4.0/5 (48 download)

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Book Synopsis Mathematical Cardiac Electrophysiology by : Piero Colli Franzone

Download or read book Mathematical Cardiac Electrophysiology written by Piero Colli Franzone and published by Springer. This book was released on 2014-11-02 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the main mathematical and numerical models in computational electrocardiology, ranging from microscopic membrane models of cardiac ionic channels to macroscopic bidomain, monodomain, eikonal models and cardiac source representations. These advanced multiscale and nonlinear models describe the cardiac bioelectrical activity from the cell level to the body surface and are employed in both the direct and inverse problems of electrocardiology. The book also covers advanced numerical techniques needed to efficiently carry out large-scale cardiac simulations, including time and space discretizations, decoupling and operator splitting techniques, parallel finite element solvers. These techniques are employed in 3D cardiac simulations illustrating the excitation mechanisms, the anisotropic effects on excitation and repolarization wavefronts, the morphology of electrograms in normal and pathological tissue and some reentry phenomena. The overall aim of the book is to present rigorously the mathematical and numerical foundations of computational electrocardiology, illustrating the current research developments in this fast-growing field lying at the intersection of mathematical physiology, bioengineering and computational biomedicine. This book is addressed to graduate student and researchers in the field of applied mathematics, scientific computing, bioengineering, electrophysiology and cardiology.

Modeling Human Atrial Patho-Electrophysiology from Ion Channels to ECG - Substrates, Pharmacology, Vulnerability, and P-Waves

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Author :
Publisher : KIT Scientific Publishing
ISBN 13 : 3731505282
Total Pages : 342 pages
Book Rating : 4.7/5 (315 download)

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Book Synopsis Modeling Human Atrial Patho-Electrophysiology from Ion Channels to ECG - Substrates, Pharmacology, Vulnerability, and P-Waves by : Loewe, Axel

Download or read book Modeling Human Atrial Patho-Electrophysiology from Ion Channels to ECG - Substrates, Pharmacology, Vulnerability, and P-Waves written by Loewe, Axel and published by KIT Scientific Publishing. This book was released on 2016-08-03 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Half of the patients suffering from atrial fibrillation (AF) cannot be treated adequately, today. This book presents multi-scale computational methods to advance our understanding of patho-mechanisms, to improve the diagnosis of patients harboring an arrhythmogenic substrate, and to tailor therapy. The modeling pipeline ranges from ion channels on the subcellular level up to the ECG on the body surface. The tailored therapeutic approaches carry the potential to reduce the burden of AF.

Differential Equations for Studies in Computational Electrophysiology

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Author :
Publisher : Springer Nature
ISBN 13 : 3031308522
Total Pages : 134 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Differential Equations for Studies in Computational Electrophysiology by : Karoline Horgmo Jæger

Download or read book Differential Equations for Studies in Computational Electrophysiology written by Karoline Horgmo Jæger and published by Springer Nature. This book was released on 2023-05-27 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access text aims at giving you the simplest possible introduction to differential equations that are used in models of electrophysiology. It covers models at several spatial and temporal scales with associated numerical methods. The text demonstrates that a very limited number of fundamental techniques can be used to define numerical methods for equations ranging from ridiculously simple to extremely complex systems of partial differential equations. Every method is implemented in Matlab and the codes are freely available online. By using these codes, the reader becomes familiar with classical models of electrophysiology, like the cable equation, the monodomain model, and the bidomain model. But modern models that have just started to gain attention in the field of computational electrophysiology are also presented. If you just want to read one book, it should probably not be this one, but if you want a simple introduction to a complex field, it is worth considering the present text.

Computational Biology of the Heart

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Author :
Publisher : Wiley-Blackwell
ISBN 13 :
Total Pages : 452 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Computational Biology of the Heart by : Alexander V. Panfilov

Download or read book Computational Biology of the Heart written by Alexander V. Panfilov and published by Wiley-Blackwell. This book was released on 1997-03-28 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modelling the genesis and propagation of electrical activity in the heart in quantitative terms is one of the most important recent applications of mathematical modelling in biology. The main research direction, and the most important for biological and medical applications, is the development of realistic models of electrical activity in cardiac tissue and the whole mammalian heart. Recent progress in nonlinear dynamics, advances in computer technology and experiments on cardiac tissue have made feasible the construction of such models. Computational Biology of the Heart is the first book to provide a comprehensive survey of recent research together with a systematic overview of the subject. The contributions, all written by experts in the different areas of the subject, cover all main aspects of whole heart modelling: from excitation in single cells, to two and three dimensional models of cardiac tissue and the whole heart. Various computational models and techniques are described and then applied to reconstruct and visualise modelled activity in both normal and pathological heart tissues. The models are nonlinear and use techniques of ordinary differential equations, partial differential equations and eikonal equations. The book also provides a review of modelling cardiac contraction, mapping electrical activity from electrocardiograms, and recent experimental observations of wave propagation in the whole heart. Graduate students and researchers in such areas as applied mathematical biology, clinical physiology and cardiology will find this book to be an invaluable resource for their work.