Computation In Cells And Tissues

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Computation in Cells and Tissues

Author : R. Paton
Publisher : Springer Science & Business Media
ISBN 13 : 3662063697
Total Pages : 349 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Computation in Cells and Tissues by : R. Paton

Download or read book Computation in Cells and Tissues written by R. Paton and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of biologically inspired computation has coexisted with mainstream computing since the 1930s, and the pioneers in this area include Warren McCulloch, Walter Pitts, Robert Rosen, Otto Schmitt, Alan Turing, John von Neumann and Norbert Wiener. Ideas arising out of studies of biology have permeated algorithmics, automata theory, artificial intelligence, graphics, information systems and software design. Within this context, the biomolecular, cellular and tissue levels of biological organisation have had a considerable inspirational impact on the development of computational ideas. Such innovations include neural computing, systolic arrays, genetic and immune algorithms, cellular automata, artificial tissues, DNA computing and protein memories. With the rapid growth in biological knowledge there remains a vast source of ideas yet to be tapped. This includes developments associated with biomolecular, genomic, enzymic, metabolic, signalling and developmental systems and the various impacts on distributed, adaptive, hybrid and emergent computation. This multidisciplinary book brings together a collection of chapters by biologists, computer scientists, engineers and mathematicians who were drawn together to examine the ways in which the interdisciplinary displacement of concepts and ideas could develop new insights into emerging computing paradigms. Funded by the UK Engineering and Physical Sciences Research Council (EPSRC), the CytoCom Network formally met on five occasions to examine and discuss common issues in biology and computing that could be exploited to develop emerging models of computation.

Computational Modeling in Tissue Engineering

Author : Liesbet Geris
Publisher : Springer Science & Business Media
ISBN 13 : 3642325637
Total Pages : 438 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Computational Modeling in Tissue Engineering by : Liesbet Geris

Download or read book Computational Modeling in Tissue Engineering written by Liesbet Geris and published by Springer Science & Business Media. This book was released on 2012-10-30 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major challenges in tissue engineering is the translation of biological knowledge on complex cell and tissue behavior into a predictive and robust engineering process. Mastering this complexity is an essential step towards clinical applications of tissue engineering. This volume discusses computational modeling tools that allow studying the biological complexity in a more quantitative way. More specifically, computational tools can help in: (i) quantifying and optimizing the tissue engineering product, e.g. by adapting scaffold design to optimize micro-environmental signals or by adapting selection criteria to improve homogeneity of the selected cell population; (ii) quantifying and optimizing the tissue engineering process, e.g. by adapting bioreactor design to improve quality and quantity of the final product; and (iii) assessing the influence of the in vivo environment on the behavior of the tissue engineering product, e.g. by investigating vascular ingrowth. The book presents examples of each of the above mentioned areas of computational modeling. The underlying tissue engineering applications will vary from blood vessels over trachea to cartilage and bone. For the chapters describing examples of the first two areas, the main focus is on (the optimization of) mechanical signals, mass transport and fluid flow encountered by the cells in scaffolds and bioreactors as well as on the optimization of the cell population itself. In the chapters describing modeling contributions in the third area, the focus will shift towards the biology, the complex interactions between biology and the micro-environmental signals and the ways in which modeling might be able to assist in investigating and mastering this complexity. The chapters cover issues related to (multiscale/multiphysics) model building, training and validation, but also discuss recent advances in scientific computing techniques that are needed to implement these models as well as new tools that can be used to experimentally validate the computational results.

Computation in Cells and Tissues

Author : R. Paton
Publisher :
ISBN 13 : 9783662063705
Total Pages : 366 pages
Book Rating : 4.0/5 (637 download)

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Book Synopsis Computation in Cells and Tissues by : R. Paton

Download or read book Computation in Cells and Tissues written by R. Paton and published by . This book was released on 2014-01-15 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Computation in Cellular and Molecular Biological Systems

Author : Roy Cuthbertson
Publisher : World Scientific
ISBN 13 : 9789810228781
Total Pages : 380 pages
Book Rating : 4.2/5 (287 download)

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Book Synopsis Computation in Cellular and Molecular Biological Systems by : Roy Cuthbertson

Download or read book Computation in Cellular and Molecular Biological Systems written by Roy Cuthbertson and published by World Scientific. This book was released on 1996 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computation in Cellular and Molecular Biological Systems is a selection of papers presented at the First International Workshop on Information Processing in Cells and Tissues (IPCAT 95). The book contains contributions from mathematicians, biochemists, cell biologists, physiologists and computer scientists. It is multidisciplinary in nature and deals with integrative aspects of information processing, cellular systems and dynamical methods.

Information Processing in Cells and Tissues

Author : Mike Holcombe
Publisher : Springer Science & Business Media
ISBN 13 : 1461553458
Total Pages : 325 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Information Processing in Cells and Tissues by : Mike Holcombe

Download or read book Information Processing in Cells and Tissues written by Mike Holcombe and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of an International Workshop held in Sheffield, UK, September 1-4, 1997

Modeling Excitable Tissue

Author : Aslak Tveito
Publisher : Springer Nature
ISBN 13 : 3030611574
Total Pages : 116 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Modeling Excitable Tissue by : Aslak Tveito

Download or read book Modeling Excitable Tissue written by Aslak Tveito and published by Springer Nature. This book was released on 2020-10-30 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access volume presents a novel computational framework for understanding how collections of excitable cells work. The key approach in the text is to model excitable tissue by representing the individual cells constituting the tissue. This is in stark contrast to the common approach where homogenization is used to develop models where the cells are not explicitly present. The approach allows for very detailed analysis of small collections of excitable cells, but computational challenges limit the applicability in the presence of large collections of cells.

Computational Biology for Stem Cell Research

Author : Pawan Raghav
Publisher : Elsevier
ISBN 13 : 0443132216
Total Pages : 568 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Computational Biology for Stem Cell Research by : Pawan Raghav

Download or read book Computational Biology for Stem Cell Research written by Pawan Raghav and published by Elsevier. This book was released on 2024-01-12 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Biology for Stem Cell Research is an invaluable guide for researchers as they explore HSCs and MSCs in computational biology. With the growing advancement of technology in the field of biomedical sciences, computational approaches have reduced the financial and experimental burden of the experimental process. In the shortest span, it has established itself as an integral component of any biological research activity. HSC informatics (in silico) techniques such as machine learning, genome network analysis, data mining, complex genome structures, docking, system biology, mathematical modeling, programming (R, Python, Perl, etc.) help to analyze, visualize, network constructions, and protein-ligand or protein-protein interactions. This book is aimed at beginners with an exact correlation between the biomedical sciences and in silico computational methods for HSCs transplantation and translational research and provides insights into methods targeting HSCs properties like proliferation, self-renewal, differentiation, and apoptosis. Modeling Stem Cell Behavior: Explore stem cell behavior through animal models, bridging laboratory studies to real-world clinical allogeneic HSC transplantation (HSCT) scenarios. Bioinformatics-Driven Translational Research: Navigate a path from bench to bedside with cutting-edge bioinformatics approaches, translating computational insights into tangible advancements in stem cell research and medical applications. Interdisciplinary Resource: Discover a single comprehensive resource catering to biomedical sciences, life sciences, and chemistry fields, offering essential insights into computational tools vital for modern research.

Information Processing in Cells and Tissues

Author : Michael A. Lones
Publisher : Springer
ISBN 13 : 3642287921
Total Pages : 278 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Information Processing in Cells and Tissues by : Michael A. Lones

Download or read book Information Processing in Cells and Tissues written by Michael A. Lones and published by Springer. This book was released on 2012-03-22 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 9th International Conference on Information in Cells and Tissues, IPCAT 2012, held in Cambridge, UK, in March/April 2012. The 13 revised full papers presented together with 26 extended abstracts were carefully reviewed and selected from numerous submissions. The papers cover a wide range of topics in disciplines related to genetic and epigenetic networks, transcriptomics and gene regulation, signalling pathways and responses, protein structure and metabolic networks, patterning and rhythm generation, neural modelling and neural networks, biomedical modelling and signal processing, information processing and representation, and algorithmic approaches in computational biology.

Computational Methods in Inferring Cancer Tissue-of-Origin and Cancer Molecular Classification, Volume I

Author : Min Tang
Publisher : Frontiers Media SA
ISBN 13 : 2889666549
Total Pages : 257 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Computational Methods in Inferring Cancer Tissue-of-Origin and Cancer Molecular Classification, Volume I by : Min Tang

Download or read book Computational Methods in Inferring Cancer Tissue-of-Origin and Cancer Molecular Classification, Volume I written by Min Tang and published by Frontiers Media SA. This book was released on 2021-04-01 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cell Biology by the Numbers

Author : Ron Milo
Publisher : Garland Science
ISBN 13 : 1317230698
Total Pages : 400 pages
Book Rating : 4.3/5 (172 download)

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Book Synopsis Cell Biology by the Numbers by : Ron Milo

Download or read book Cell Biology by the Numbers written by Ron Milo and published by Garland Science. This book was released on 2015-12-07 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid

Methods and Models in Artificial and Natural Computation. A Homage to Professor Mira's Scientific Legacy

Author : Jose Mira
Publisher : Springer Science & Business Media
ISBN 13 : 3642022634
Total Pages : 550 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Methods and Models in Artificial and Natural Computation. A Homage to Professor Mira's Scientific Legacy by : Jose Mira

Download or read book Methods and Models in Artificial and Natural Computation. A Homage to Professor Mira's Scientific Legacy written by Jose Mira and published by Springer Science & Business Media. This book was released on 2009-06-12 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two-volume set LNCS 5601 and LNCS 5602 constitutes the refereed proceedings of the Third International Work-Conference on the Interplay between Natural and Artificial Computation, IWINAC 2009, held in Santiago de Compostela, Spain, in June 2009. The 108 revised papers presented are thematically divided into two volumes. The first volume includes papers relating the most recent collaborations with Professor Mira and contributions mainly related with theoretical, conceptual and methodological aspects linking AI and knowledge engineering with neurophysiology, clinics and cognition. The second volume contains all the contributions connected with biologically inspired methods and techniques for solving AI and knowledge engineering problems in different application domains.

The Computational Mechanics of Bone Tissue

Author : Jorge Belinha
Publisher : Springer Nature
ISBN 13 : 3030375412
Total Pages : 249 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis The Computational Mechanics of Bone Tissue by : Jorge Belinha

Download or read book The Computational Mechanics of Bone Tissue written by Jorge Belinha and published by Springer Nature. This book was released on 2020-02-11 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a timely snapshot of computational methods applied to the study of bone tissue. The bone, a living tissue undergoing constant changes, responds to chemical and mechanical stimuli in order to maximize its mechanical performance. Merging perspectives from the biomedical and the engineering science fields, the book offers some insights into the overall behavior of this complex biological tissue. It covers three main areas: biological characterization of bone tissue, bone remodeling algorithms, and numerical simulation of bone tissue and adjacent structures. Written by clinicians and researchers, and including both review chapters and original research, the book offers an overview of the state-of-the-art in computational mechanics of bone tissue, as well as a good balance of biological and engineering methods for bone tissue analysis. An up-to-date resource for mechanical and biomedical engineers seeking new ideas, it also promotes interdisciplinary collaborations to advance research in the field.

Membrane Computing

Author : David Corne
Publisher : Springer Science & Business Media
ISBN 13 : 3540958843
Total Pages : 412 pages
Book Rating : 4.5/5 (49 download)

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Book Synopsis Membrane Computing by : David Corne

Download or read book Membrane Computing written by David Corne and published by Springer Science & Business Media. This book was released on 2009-01-20 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the thoroughly refereed extended postproceedings of the 9th International Workshop on Membrane Computing, WMC 2008, held in Edinburgh, UK, in July 2008 under the auspices of the European Molecular Computing Consortium (EMCC) and the Molecular Computing Task Force of IEEE Computational Intelligence Society. The 22 revised full papers presented together with 5 invited papers went through two rounds of reviewing and improvement. The papers in this volume cover all the main directions of research in membrane computing, ranging from theoretical topics in mathematics and computer science to application issues. A special attention was paid to the interaction of membrane computing with biology and computer science, focusing both on the biological roots of membrane computing, on applications of membrane computing in biology and medicine, and on possible electronically based implementations.

Membrane Computing

Author : George Eleftherakis
Publisher : Springer
ISBN 13 : 3540773126
Total Pages : 456 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Membrane Computing by : George Eleftherakis

Download or read book Membrane Computing written by George Eleftherakis and published by Springer. This book was released on 2007-11-25 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: For anyone needing to keep up to date with all the latest research in the field of membrane computing, this book will come as a breath of fresh air. It is the extended post-proceedings of the 8th International Workshop on Membrane Computing, held in June 2007. A total of 27 revised papers are presented. All of them have been through two rounds of reviewing. Special attention has been paid to the interaction of membrane computing with biology and computer science.

Computing with Cells

Author : Pierluigi Frisco
Publisher : OUP Oxford
ISBN 13 : 0191579637
Total Pages : 368 pages
Book Rating : 4.1/5 (915 download)

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Book Synopsis Computing with Cells by : Pierluigi Frisco

Download or read book Computing with Cells written by Pierluigi Frisco and published by OUP Oxford. This book was released on 2009-05-21 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Membrane systems are a new class of distributed and parallel model of computation inspired by the subdivision of living cells into compartments delimited by membranes. Their hierarchical internal structure, their locality of interactions, their inherent parallelism and also their capacity to create new compartments, represent the distinguishing hallmarks of membrane systems. Membrane computing, the study of membrane systems, is a fascinating and fast growing area of research. The main streams of current investigations in Membrane Computing concern theoretical computer science and the modelling of complex systems. In this monograph Pierluigi Frisco considers the former trend: he presents an in-depth study of the formal language and computational complexity aspects of the most widely investigated models of membrane systems. This study gives a comprehensive understanding of the computational power of the models considered, shows different proof techniques used for such study, and introduces links highlighting the similarities and differences between the their computational power. These models cover a broad range of features, giving a grasp of the enormous flexibility of the framework offered by membrane systems. Aimed at graduates and researchers in the field, who can use it as a reference text, and to people with an initial interest in Membrane Computing, who can use it as a clear and up to date starting point for Membrane Computing.

Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System

Author : Z Jin
Publisher : Elsevier
ISBN 13 : 0857096737
Total Pages : 550 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System by : Z Jin

Download or read book Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System written by Z Jin and published by Elsevier. This book was released on 2014-05-05 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System reviews how a wide range of materials are modelled and how this modelling is applied. Computational modelling is increasingly important in the design and manufacture of biomedical materials, as it makes it possible to predict certain implant-tissue reactions, degradation, and wear, and allows more accurate tailoring of materials' properties for the in vivo environment. Part I introduces generic modelling of biomechanics and biotribology with a chapter on the fundamentals of computational modelling of biomechanics in the musculoskeletal system, and a further chapter on finite element modelling in the musculoskeletal system. Chapters in Part II focus on computational modelling of musculoskeletal cells and tissues, including cell mechanics, soft tissues and ligaments, muscle biomechanics, articular cartilage, bone and bone remodelling, and fracture processes in bones. Part III highlights computational modelling of orthopedic biomaterials and interfaces, including fatigue of bone cement, fracture processes in orthopedic implants, and cementless cup fixation in total hip arthroplasty (THA). Finally, chapters in Part IV discuss applications of computational modelling for joint replacements and tissue scaffolds, specifically hip implants, knee implants, and spinal implants; and computer aided design and finite element modelling of bone tissue scaffolds. This book is a comprehensive resource for professionals in the biomedical market, materials scientists and mechanical engineers, and those in academia. Covers generic modelling of cells and tissues; modelling of biomaterials and interfaces; biomechanics and biotribology Discusses applications of modelling for joint replacements and applications of computational modelling in tissue engineering

Molecular Computing and Bioinformatics

Author : Xiangxiang Zeng
Publisher : MDPI
ISBN 13 : 3039211951
Total Pages : 390 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Molecular Computing and Bioinformatics by : Xiangxiang Zeng

Download or read book Molecular Computing and Bioinformatics written by Xiangxiang Zeng and published by MDPI. This book was released on 2019-07-11 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text will provide the most recent knowledge and advances in the area of molecular computing and bioinformatics. Molecular computing and bioinformatics have a close relationship, paying attention to the same object but working towards different orientations. The articles will range from topics such as DNA computing and membrane computing to specific biomedical applications, including drug R&D and disease analysis.