Comprehensive Natural Products Chemistry: Enzymes, enzyme mechanisms, proteins, and aspects of NO chemistry

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Publisher : Elsevier Publishing Company
ISBN 13 :
Total Pages : 542 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Comprehensive Natural Products Chemistry: Enzymes, enzyme mechanisms, proteins, and aspects of NO chemistry by : Derek H. R. Barton

Download or read book Comprehensive Natural Products Chemistry: Enzymes, enzyme mechanisms, proteins, and aspects of NO chemistry written by Derek H. R. Barton and published by Elsevier Publishing Company. This book was released on 1999 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hardbound. This volume describes the dramatic advances in studies of the structure and function of enzymes which have led to an understanding of the rich chemistry used by nature to construct molecules and how the enzymes of natural products biosynthesis catalyze these reactions. Natural products are synthesized from simple precursors through a series of enzyme mediated reactions that are exquisitely selective and efficient. Questions about the mechanisms of these reactions and what features of enzyme catalytic sites are important for stabilizing transition states and reactive intermediates have been addressed by combining studies in mechanistic organic chemistry, structural biology, and molecular genetics. Except in rare instances, the enzymes of natural products biosynthesis are not found in abundance, and as a consequence, they are not readily available for study from natural sources. This situation has changed through the dramatic advances in gen

Comprehensive Natural Products Chemistry

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Publisher : Newnes
ISBN 13 : 0080912834
Total Pages : 11380 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Comprehensive Natural Products Chemistry by : Derek Barton

Download or read book Comprehensive Natural Products Chemistry written by Derek Barton and published by Newnes. This book was released on 1999-02-18 with total page 11380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Natural Products Chemistry

Comprehensive Natural Products II

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Publisher :
ISBN 13 : 9780080453903
Total Pages : 747 pages
Book Rating : 4.4/5 (539 download)

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Book Synopsis Comprehensive Natural Products II by : Lew Mander

Download or read book Comprehensive Natural Products II written by Lew Mander and published by . This book was released on 2010 with total page 747 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Comprehensive Natural Products III

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Publisher : Elsevier
ISBN 13 : 0081026919
Total Pages : 4266 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Comprehensive Natural Products III by :

Download or read book Comprehensive Natural Products III written by and published by Elsevier. This book was released on 2020-07-22 with total page 4266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Natural Products III, Third Edition, Seven Volume Set updates and complements the previous two editions, including recent advances in cofactor chemistry, structural diversity of natural products and secondary metabolites, enzymes and enzyme mechanisms and new bioinformatics tools. Natural products research is a dynamic discipline at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids and enzymes. This book reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine and to stimulate new ideas among the established natural products community. Provides readers with an in-depth review of current natural products research and a critical insight into the future direction of the field Bridges the gap in knowledge by covering developments in the field since the second edition published in 2010 Split into 7 sections on key topics to allow students, researchers and professionals to find relevant information quickly and easily Ensures that the knowledge within is easily understood by and applicable to a large audience

DNA and Aspects of Molecular Biology

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Publisher : Pergamon
ISBN 13 : 9780080431659
Total Pages : 0 pages
Book Rating : 4.4/5 (316 download)

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Book Synopsis DNA and Aspects of Molecular Biology by : Eric T. Kool

Download or read book DNA and Aspects of Molecular Biology written by Eric T. Kool and published by Pergamon. This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is intended to cover the chemistry of one of the most widely studied and important natural products, DNA. Discussed in detail are physicochemical properties of the molecule itself as well as small-molecule natural products that are known to interact with it. Also included are methods to synthesize and manipulate DNA and modified analogues. Twenty chapters are devoted to this overall topic. thermodynamics and kinetics of double helix formation; the next two describe triple- and tetra- helical structures formed by DNA; and the last two focus on methods for probing DNA structure (specifically, NMR methods and chemical probing methods, respectively). analogues. The first of these addresses nonenzymatic methods for synthesizing DNA, and the next chapter, methods for attachment of reporter groups to it. Modifications of DNA structure are discussed in chapters eight to eleven; the first of these addresses nucleoside analogues useful as biochemical probes, while others discuss alterations to the DNA backbone, bases, and topology, respectively. The extensive chemistry of DNA damage is reviewed in the last chapter (chapter 12). Included in this group are a large number of natural and non-natural products, which fall into the classes of intercalators (chapter 13), minor groove binders (chapter 14), DNA-binding peptides (chapter 15), and DNA-damaging natural products (chapter 16). The last two chapters focus more specifically on two broad classes of medicinally important agents which interact with DNA; specifically, the enediyne natural products (chapter 17), and topoisomerase inhibitors (chapter 18). are being used in many chemically-oriented laboratories. The first (chapter 19) covers selection of novel ligands and catalysts from sequence-randomized libraries of DNA. The second (chapter 20) covers other useful molecular biology methods such as cloning and the polymerase chain reaction.

Chemistry of Natural Products

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Publisher : Springer Nature
ISBN 13 : 303086698X
Total Pages : 250 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Chemistry of Natural Products by : V.K. Ahluwalia

Download or read book Chemistry of Natural Products written by V.K. Ahluwalia and published by Springer Nature. This book was released on 2022-11-30 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to serve as a textbook for core as well as elective courses offered to undergraduate and advanced undergraduate students enrolled in chemistry. This textbook comprehensively deals various topics of organic chemistry such as amino acids, peptides, proteins and enzymes. The text is divided into four chapters: a chapter each dedicated to amino acids, peptides, proteins and enzymes, respectively. The important reactions have been explained with the help of the mechanisms involved. It gives a detailed account of the solution phase and solid phase synthesis of peptides as well as discussing the structure and function of some biologically important peptides. It also covers the classification, nomenclature and mode of action of enzymes, and a detailed account of the structure and function of different co-enzymes. The book also includes pedagogical features like end-of-chapter exercises to aid in self learning. Given the scope, this textbook will be useful for graduate and advanced graduate students pursuing the course of chemistry, especially organic chemistry.

Molecular Biology of the Cell

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Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chemistry of Plant Phosphorus Compounds

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Publisher : Elsevier
ISBN 13 : 0124072232
Total Pages : 688 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Chemistry of Plant Phosphorus Compounds by : Arlen Frank

Download or read book Chemistry of Plant Phosphorus Compounds written by Arlen Frank and published by Elsevier. This book was released on 2013-06-03 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a high level reference source for scientists engaged in any aspect of plant research - chemistry, biochemistry or physiology - with primary focus on the chemistry of phosphorus-containing compounds that occur naturally in the plant kingdom, and specifically in the higher plants (Plantae). The book is comprehensive with respect to nomenclature, physical properties, and distribution worldwide. There are many tables of actual data on phosphorus compounds occurring in whole plants and parts of plants. The tables provide detailed data that is needed by the food industry, agriculture, etc as many of the phosphorus compounds are common to both plants and animals. Two appendices cover other aspects including changes in phosphorus-containing compounds during germination and their accumulation during growth and senescence. The final sections of the book comprise separate indexes of plants, compounds and authors. Comprehensive examination of phosphorus compounds found in plants Extensive tables listing types of compounds and their occurrence in plants including: Nomenclature; Occurrence; Physical Properties; Synthesis; Hydrolysis; Phosphorylation; Extraction; Separation and Analysis Easy to use indexes of plants, compounds and authors

Organic Syntheses Based on Name Reactions and Unnamed Reactions

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Publisher : Elsevier
ISBN 13 : 1483287343
Total Pages : 462 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Organic Syntheses Based on Name Reactions and Unnamed Reactions by : Alfred Hassner

Download or read book Organic Syntheses Based on Name Reactions and Unnamed Reactions written by Alfred Hassner and published by Elsevier. This book was released on 2013-10-22 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetically useful organic reactions or reagents are often referred to by the name of the discoverer(s) or developer(s). Older name reactions are described in text books, but more recently developed synthetically useful reactions that may have been associated occasionally with a name are not always well known. For neither of the above are experimental procedures or references easy to find. In this monograph approximately 500 name reactions are included, of which over 200 represent newer name reactions and modern reagents. Each of these reactions are extremely useful for the contemporary organic chemistry researcher in industry or academic institutions. This book provides the information in an easily accessible form. In addition to seminal references and reviews, one or more examples for each name reaction are provided and a complete typical experimental procedure is included, to enable the student or researcher to immediately evaluate reaction conditions. Besides an alphabetical listing of reactions and reagents, cross references permit the organic practitioner to find those name reactions or reagents that enable specific transformations, such as, conversion of amines to nitriles, stereoselective reduction, fluoroalkylation, phenol alkynylation, asymmetric syntheses, allylic alkylation, nucleoside synthesis, cyclopentanation, hydrozirconation, to name a few. Emphasis has been placed on stereoselective and regioselective transformations as well as on enantioselective processes. The listing of reactions and reagents is supported by four indexes.

Introduction to Enzyme and Coenzyme Chemistry

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Publisher : John Wiley & Sons
ISBN 13 : 1118348990
Total Pages : 310 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Introduction to Enzyme and Coenzyme Chemistry by : T. D. H. Bugg

Download or read book Introduction to Enzyme and Coenzyme Chemistry written by T. D. H. Bugg and published by John Wiley & Sons. This book was released on 2012-05-29 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enzymes are giant macromolecules which catalyse biochemical reactions. They are remarkable in many ways. Their three-dimensional structures are highly complex, yet they are formed by spontaneous folding of a linear polypeptide chain. Their catalytic properties are far more impressive than synthetic catalysts which operate under more extreme conditions. Each enzyme catalyses a single chemical reaction on a particular chemical substrate with very high enantioselectivity and enantiospecificity at rates which approach “catalytic perfection”. Living cells are capable of carrying out a huge repertoire of enzyme-catalysed chemical reactions, some of which have little or no precedent in organic chemistry. The popular textbook Introduction to Enzyme and Coenzyme Chemistry has been thoroughly updated to include information on the most recent advances in our understanding of enzyme action, with additional recent examples from the literature used to illustrate key points. A major new feature is the inclusion of two-colour figures, and the addition of over 40 new figures of the active sites of enzymes discussed in the text, in order to illustrate the interplay between enzyme structure and function. This new edition provides a concise but comprehensive account from the perspective of organic chemistry, what enzymes are, how they work, and how they catalyse many of the major classes of enzymatic reactions, and will continue to prove invaluable to both undergraduate and postgraduate students of organic, bio-organic and medicinal chemistry, chemical biology, biochemistry and biotechnology.

Comprehensive Natural Products Chemistry: DNA and aspects of molecular biology

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Author :
Publisher : Elsevier Publishing Company
ISBN 13 :
Total Pages : 780 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Comprehensive Natural Products Chemistry: DNA and aspects of molecular biology by : Derek H. R. Barton

Download or read book Comprehensive Natural Products Chemistry: DNA and aspects of molecular biology written by Derek H. R. Barton and published by Elsevier Publishing Company. This book was released on 1999 with total page 780 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hardbound. This volume is intended to cover the chemistry of one of the most widely studied and important natural products, DNA. Discussed in detail are physicochemical properties of the molecule itself as well as small-molecule natural products that are known to interact with it. Also included are methods to synthesize and manipulate DNA and modified analogues. Twenty chapters are devoted to this overall topic.The first five relate to the structure of DNA; the first focuses on thermodynamics and kinetics of double helix formation; the next two describe triple- and tetra- helical structures formed by DNA; and the last two focus on methods for probing DNA structure (specifically, NMR methods and chemical probing methods, respectively).Chapters 6-12 focus on the chemistry of natural DNA and modified analogues. The first of these addresses nonenzymatic methods for synthesizing DNA, and the next chapter, on methods for attachment of reporter groups t

Medicinal Natural Products

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Publisher : John Wiley & Sons
ISBN 13 : 9780471496410
Total Pages : 524 pages
Book Rating : 4.4/5 (964 download)

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Book Synopsis Medicinal Natural Products by : Paul M. Dewick

Download or read book Medicinal Natural Products written by Paul M. Dewick and published by John Wiley & Sons. This book was released on 2002-01-03 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guide covers classes of natural products in medicine, whether derived from plants, micro-organisms or animals. Structured according to biosynthetic pathway, it is written from a chemistry-based approach.

Natural Products Chemistry

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Publisher : Elsevier
ISBN 13 : 1483218872
Total Pages : 597 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Natural Products Chemistry by : Koji Nakanishi

Download or read book Natural Products Chemistry written by Koji Nakanishi and published by Elsevier. This book was released on 2013-10-22 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Products Chemistry, Volume 2 covers the introductory survey, history, structure, synthesis, reactions, and biosynthesis of natural products such as the fatty acid derivatives and related compounds; sugars (carbohydrates); carboaromatic and related compounds; alkaloids; and non-alkaloidal nitrogen compounds. The text also describes the aspects of natural products photochemistry.

Natural Product Biosynthesis

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Publisher : Royal Society of Chemistry
ISBN 13 : 1788010760
Total Pages : 787 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Natural Product Biosynthesis by : Christopher T. Walsh

Download or read book Natural Product Biosynthesis written by Christopher T. Walsh and published by Royal Society of Chemistry. This book was released on 2017-04-28 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook describes the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era.

Enzymes in Food Biotechnology

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Publisher : Academic Press
ISBN 13 : 0128132817
Total Pages : 912 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Enzymes in Food Biotechnology by : Mohammed Kuddus

Download or read book Enzymes in Food Biotechnology written by Mohammed Kuddus and published by Academic Press. This book was released on 2018-08-23 with total page 912 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enzymes in Food Biotechnology: Production, Applications, and Future Prospects presents a comprehensive review of enzyme research and the potential impact of enzymes on the food sector. This valuable reference brings together novel sources and technologies regarding enzymes in food production, food processing, food preservation, food engineering and food biotechnology that are useful for researchers, professionals and students. Discussions include the process of immobilization, thermal and operational stability, increased product specificity and specific activity, enzyme engineering, implementation of high-throughput techniques, screening to relatively unexplored environments, and the development of more efficient enzymes. Explores recent scientific research to innovate novel, global ideas for new foods and enzyme engineering Provides fundamental and advanced information on enzyme research for use in food biotechnology, including microbial, plant and animal enzymes Includes recent cutting-edge research on the pharmaceutical uses of enzymes in the food industry

Organic Synthesis Using Biocatalysis

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Publisher : Academic Press
ISBN 13 : 012411542X
Total Pages : 440 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Organic Synthesis Using Biocatalysis by : Animesh Goswami

Download or read book Organic Synthesis Using Biocatalysis written by Animesh Goswami and published by Academic Press. This book was released on 2015-09-06 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Synthesis Using Biocatalysis provides a concise background on the application of biocatalysis for the synthesis of organic compounds, including the important biocatalytic reactions and application of biocatalysis for the synthesis of organic compounds in pharmaceutical and non-pharmaceutical areas. The book provides recipes for carrying out various biocatalytic reactions, helping both newcomers and non-experts use these methodologies. It is written by experts in their fields, and provides both a current status and future prospects of biocatalysis in the synthesis of organic molecules. Provides a concise background of the application of biocatalysis for the synthesis of organic compounds Expert contributors present recipes for carrying out biocatalytic reactions, including subject worthy discussions on biocatalysis in organic synthesis, biocatalysis for selective organic transformation, enzymes as catalysis for organic synthesis, biocatalysis in Industry, including pharmaceuticals, and more Contains detailed, separate chapters that describe the application of biocatalysis

Comprehensive Natural Products II

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Publisher : Elsevier
ISBN 13 : 0080453821
Total Pages : 7944 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Comprehensive Natural Products II by :

Download or read book Comprehensive Natural Products II written by and published by Elsevier. This book was released on 2010-03-05 with total page 7944 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work presents a definitive interpretation of the current status of and future trends in natural products—a dynamic field at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids, and enzymes. With more than 1,800 color figures, Comprehensive Natural Products II features 100% new material and complements rather than replaces the original work (©1999). Reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine Stimulates new ideas among the established natural products research community—which includes chemists, biochemists, biologists, botanists, and pharmacologists Informs and inspires students and newcomers to the field with accessible content in a range of delivery formats Includes 100% new content, with more than 6,000 figures (1/3 of these in color) and 40,000 references to the primary literature, for a thorough examination of the field Highlights new research and innovations concerning living organisms and their distinctive role in our understanding and improvement of human health, genomics, ecology/environment, and more Adds to the rich body of work that is the first edition, which will be available for the first time in a convenient online format giving researchers complete access to authoritative Natural Products content