Comparison Of 2 Types Of Ultrasound Guided Nerve Blocks In Patients Undergoing Breast Cancer Surgery Under Opioid Free Anaesthesia

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Total Pages : pages
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Book Synopsis Comparison Of 2 Types Of Ultrasound Guided Nerve Blocks In Patients Undergoing Breast Cancer Surgery Under Opioid Free Anaesthesia by :

Download or read book Comparison Of 2 Types Of Ultrasound Guided Nerve Blocks In Patients Undergoing Breast Cancer Surgery Under Opioid Free Anaesthesia written by and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Background and Goal of Study: Having demonstrated that PECs ( Pectoral block ) based anesthesia without opioids has decreased analgesic requirement, pain scores and PONV compared to conventional general anesthesia in patients of modified radical mastectomy and axillary dissection (MRM- AD) we wished to compare PECS vs Paravertebral Blocks (PVB) in an opioid free, nerve block based anesthesia. Outcomes of interest were post operative analgesic requirement, duration of analgesia, PONV and satisfaction of patient and surgeons. Materials and Methods: This randomized double blind study involving 58 adult ASA I-III patients posted for MRM-AD in a 500 bedded university hospital. After randomization and allocation concealment patients were induced with propofol and maintained on spontaneous ventilation with isoflurane (0.8- 1.0 MAC) through i-gel. Ultrasound guided PECS or paravertebral blocks (0.1% lignocaine+0.25% bupivacaine+1 mcg /kg dexmedetomidine, 30ml) were administered. Intraoperative events, post-operative pain scores and analgesic requirement over 24 hours, PONV, satisfaction of surgeon and patient were measured. Results- Between the two groups, there was no difference in demographics, ASA status, location and volume of breast tumour excised or the duration of surgery. The time from block to incision was significantly more in the PV group (p = 0.01). There was no difference between the two groups in terms of intra and post operative parameters, and the median VAS scores for pain at rest or during shoulder abduction was similar in both the groups. Discussion- Duration of analgesia is similar between Pecs or PVB block aided opioid free anesthesia for MRM-AD.Time from block to incision is less and surgeon satisfaction better with PECS. This is unlike the results of Wahba et al and Kulhari et al where Pecs block was superior to paravertebral block. Conclusion- Both Pecs and Paravertebral blocks result in prolonged analgesia and decreased requirement of non-opiate opioid analgesics when administered in a opioid free regimen. Pecs block is associated with less time to incision and is preferred by surgeons. Incidence of PONV and complications are low. Benefits of routine used of these blocks to avoid opioid related complications may be studied futher.

Perioperative Pain Management

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Publisher : John Wiley & Sons
ISBN 13 : 1444309595
Total Pages : 336 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Perioperative Pain Management by : Felicia Cox

Download or read book Perioperative Pain Management written by Felicia Cox and published by John Wiley & Sons. This book was released on 2009-03-17 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Perioperative Pain Management is an up-to-date evidence-based guide to the effective management of perioperative pain even in the most challenging situations. It provides readers with an understanding of the physiology, pharmacology and psychology of acute pain together with guidelines for best practice. Examples of assessment documentation and guidelines for specific patient sub-groups are reproduced throughout the text.

Chronic Postsurgical Pain

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Publisher : Springer Science & Business Media
ISBN 13 : 3319043226
Total Pages : 175 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Chronic Postsurgical Pain by : Gérard Mick

Download or read book Chronic Postsurgical Pain written by Gérard Mick and published by Springer Science & Business Media. This book was released on 2014-02-20 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: Primum non nocere... The fact that a surgical procedure can leave any kind of pain casts a shadow over this tenet, which is seen as the basis of medical practice and anchor of its principle ethic... It is all the more surprising in that medicine has only paid attention to this paradoxical chronic pain situation for the past few years. Clarifying the knowledge acquired in this field has become all the more urgent for any care-giver today confronted by a legitimate request from patients: Why and how can a surgical procedure, which is supposed to bring relief, leave behind an unacceptable sequela? This is the approach which the contributors to this new subject of major clinical interest invite you to follow as you work your way through this book.

Perioperative Pain Management

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Publisher : Oxford University Press
ISBN 13 : 0199937214
Total Pages : 141 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis Perioperative Pain Management by : Richard D. Urman

Download or read book Perioperative Pain Management written by Richard D. Urman and published by Oxford University Press. This book was released on 2013-05-23 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perioperative Pain Management is an up-to-date, evidence-based guide for clinicians who diagnose and treat post-surgical patients.

ULTRASOUND GUIDED PECTORAL NERVES (USG PECS) I AND II BLOCK VERSUS SURGEON ADMINISTERED LOCAL ANAESTHETIC IN BREAST SURGERY: RETROSPECTIVE CASE SERIES

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (116 download)

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Book Synopsis ULTRASOUND GUIDED PECTORAL NERVES (USG PECS) I AND II BLOCK VERSUS SURGEON ADMINISTERED LOCAL ANAESTHETIC IN BREAST SURGERY: RETROSPECTIVE CASE SERIES by : Woei Lin Yap

Download or read book ULTRASOUND GUIDED PECTORAL NERVES (USG PECS) I AND II BLOCK VERSUS SURGEON ADMINISTERED LOCAL ANAESTHETIC IN BREAST SURGERY: RETROSPECTIVE CASE SERIES written by Woei Lin Yap and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: USG PECS I and II blocks are relatively new interfascial plane blocks and are gaining popularity in breast surgery. They have been shown to reduce postoperative pain and opioid consumption compared to GA alone1,2 and when combined with continuous local anaesthetic (LA) infusion.3 However, literature comparing PECS block to local anaesthetic wound infiltration is limited. Our retrospective study compares USG PECS Block versus surgeon administered LA wound infiltration (WI) in terms of postoperative analgesia, antiemetic usage, time spent in anaesthetic room and complications.Methods: All patients undergoing wide local excision and breast biopsy from 03/05/18 to 19/10/18 were included. Data was collected from anaesthetic charts and electronic prescriptions. Primary outcomes were 24-hour postoperative analgesia consumption, antiemetic consumption and time spent in the anaesthetic room.Results: Twenty-seven patients were included in our study. Seven patients received USG PECS block and 20 patients received WI by surgeons. Within the PECS group, 3 patients received PECS II, 3 patients received both PECS I&II and 1 patient received PECS I block (table 1). Both groups received similar total doses of LA.Conclusion:We found no significant difference in analgesia usage between the two groups. More patients required antiemetic post-surgery in the PECS block group. There was no difference in time spent in the anaesthetic room between the two groups. No complications were reported in either group. Further randomised controlled trials are needed to investigate the mooted benefits of PECS block and explore local anaesthetic WI as a potentially effective and safe alternative to PECS block.

Ultrasound-Guided Peripheral Nerve Blocks

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Publisher : Springer
ISBN 13 : 3319710206
Total Pages : 153 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Ultrasound-Guided Peripheral Nerve Blocks by : Enzo Silvestri

Download or read book Ultrasound-Guided Peripheral Nerve Blocks written by Enzo Silvestri and published by Springer. This book was released on 2018-05-24 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a comprehensive but straightforward, practical handbook on ultrasound (US)-guided nerve blocks. It presents the normal US anatomy of peripheral nerves, clinical aspects of nerve entrapment and different procedures / techniques for each block. Axial or peripheral chronic radicular pain can be particularly severe and debilitating for the patient. The aim of treatment is to provide medium-/ long-term pain relief, and consequently to restore function. The therapeutic nerve block, performed with a perineural injection of anaesthetic, steroid or painkiller, is generally used once conservative treatments have proven unsuccessful and is aimed to avoid surgical options. Ultrasound guidance, offering the direct and real-time visualization of the needle and adjacent relevant anatomic structures, significantly increases the accuracy and safety of nerve blocks reducing the risk of intraneural or intravascular injection and the potential damage to the surrounding structures, but also enhances the efficacy of the block itself, reducing its onset and drug doses. This practical volume addresses the needs of physicians dealing with pain management, e.g. anaesthesiologists, radiologists, orthopaedists and physiatrists, with various levels of experience, ranging from physicians in training to those who already perform peripheral nerve blocks with traditional techniques and who want to familiarize with US guided procedures.

Essential Clinical Anesthesia

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Publisher : Cambridge University Press
ISBN 13 : 1139498401
Total Pages : 1191 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Essential Clinical Anesthesia by : Charles Vacanti

Download or read book Essential Clinical Anesthesia written by Charles Vacanti and published by Cambridge University Press. This book was released on 2011-07-11 with total page 1191 pages. Available in PDF, EPUB and Kindle. Book excerpt: The clinical practice of anesthesia has undergone many advances in the past few years, making this the perfect time for a new state-of-the-art anesthesia textbook for practitioners and trainees. The goal of this book is to provide a modern, clinically focused textbook giving rapid access to comprehensive, succinct knowledge from experts in the field. All clinical topics of relevance to anesthesiology are organized into 29 sections consisting of more than 180 chapters. The print version contains 166 chapters that cover all of the essential clinical topics, while an additional 17 chapters on subjects of interest to the more advanced practitioner can be freely accessed at www.cambridge.org/vacanti. Newer techniques such as ultrasound nerve blocks, robotic surgery and transesophageal echocardiography are included, and numerous illustrations and tables assist the reader in rapidly assimilating key information. This authoritative text is edited by distinguished Harvard Medical School faculty, with contributors from many of the leading academic anesthesiology departments in the United States and an introduction from Dr S. R. Mallampati. This book is your essential companion when preparing for board review and recertification exams and in your daily clinical practice.

Postoperative Analgesia Requirements After Propofol Anaesthesia with Intercostal Nerve Block Versus Sevofluorane and Opioids for Breast Cancer Surgery

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (116 download)

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Book Synopsis Postoperative Analgesia Requirements After Propofol Anaesthesia with Intercostal Nerve Block Versus Sevofluorane and Opioids for Breast Cancer Surgery by : Veru00f3nica Lu00f3pez Pu00e9rez

Download or read book Postoperative Analgesia Requirements After Propofol Anaesthesia with Intercostal Nerve Block Versus Sevofluorane and Opioids for Breast Cancer Surgery written by Veru00f3nica Lu00f3pez Pu00e9rez and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Comparation of pectoral block/propofol anaesthesia versus sevofluorane/fentanyl anaesthesia for breast cancer surgeryBackground: Breast cancer surgery is one of the most frequently performed surgeries. This include tumorectomies and mastectomies with axillary clearance when needed. Even relatively minor breast surgery can be associated with significant postoperative pain. Thoracic epidural analgesia, paravertebral blocks and other regional techniques are commonly associated to general anaesthesia.Intercostal nerve block (PIB) is another alternative described as particularly useful for ambulatory patients Goal of study: We aim to demostrate that PIB provides better postoperative analgesia than general anaesthesia with sevofluorane and opioids (SAO) with less nausea and vomiting (PONV) and better patient comfort.Material & Methods: 20 women with diagnosis of breast cancer were randomized to recieve either PIB, with 20 ml chirocane 0.25% , performed under ultrasound guidance , or SAO anesthesia. Intraoperative fentanyl consumption, postoperative Visual analogic scale (VAS) pain scores at 1 and 24 h postoperative, postoperative fentanyle consumption, PONV scores and postsurgical hospital stay were recorded.Resultados: Patient demographics and duration of surgery were comparable for both groups(Fig I). PIB group had no need of opioids in the recovery room and presented significantly lower VAS pain scores and less PONV scores.There was no difference in hospital stay or intraoperative fentanyl(Fig 2).Discursion:Intercostal nerve block is easy to perform and is associated to less adverse events then epidural o paravertebral block,

Clinical Ambulatory Anesthesia

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Publisher : Cambridge University Press
ISBN 13 : 1139488864
Total Pages : pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Clinical Ambulatory Anesthesia by : Johan Raeder

Download or read book Clinical Ambulatory Anesthesia written by Johan Raeder and published by Cambridge University Press. This book was released on 2010-06-10 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Ambulatory care can be a challenging setting in which to provide anesthesia – not all patients are suitable for rapid discharge post-operatively and opinions differ as to which types of surgery should be performed as day cases. This comprehensive guide delivers up-to-date, evidence-based advice on how to provide optimal anesthesia care for ambulatory surgery. Written by a leading clinical anesthesiologist, it provides clear guidance about how to handle particular patients in particular situations. The evidence and scientific knowledge for each issue are presented with reference to major studies and review papers, followed by practical advice based on the author's continuous clinical and scientific experience over 30 years. Topics include planning, equipping and staffing ambulatory units, pharmacology, basic concepts of ambulatory care, pre- and post-operative issues and current controversies. Clinical Ambulatory Anesthesia is essential reading for the clinical, postgraduate anesthesiologist as well as nurse anesthetists involved with ambulatory care.

Plastic Surger: 6 Volume Set - E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323830285
Total Pages : 6280 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Plastic Surger: 6 Volume Set - E-Book by : Peter C. Neligan

Download or read book Plastic Surger: 6 Volume Set - E-Book written by Peter C. Neligan and published by Elsevier Health Sciences. This book was released on 2023-09-25 with total page 6280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive and fully up to date, Dr. Peter Neligan’s six-volume masterwork, Plastic Surgery, 5th Edition, remains the gold standard text in this complex area of surgery. Completely revised to meet the demands of both the trainee and experienced surgeon, it features new, full-color clinical photos, procedural videos, and lectures across all six volumes. Bonus material online includes additional text, images, and over 200 procedural videos that help you improve your mastery of the latest techniques. Easily find the answers you need with an organization that features separate volumes covering Principles • Aesthetic • Craniofacial, Head and Neck Surgery and Pediatric Plastic Surgery • Lower Extremity, Trunk and Burns • Breast • and Hand and Upper Extremity. Each easily readable, individual volume is a standalone comprehensive text full of salient and applicable anatomy and techniques. Key procedures include gender affirmation management and surgery, microsurgery and surgery for lymphedema, aesthetic facial surgery, aesthetic body surgery, and the education, training and practice of plastic surgery. New digital video preface by Dr. Neligan addresses the changes across all six volumes. New treatment and decision-making algorithms added to chapters where applicable. New video lectures and editor-narrated slide presentations offer a step-by-step audiovisual walkthrough of techniques and procedures. Four new international experts join the editorial team, and lead editor Peter C. Neligan creates a cohesive tone throughout the chapters and content across all six volumes. Evidence-based advice from a diverse collection of experts allows you to apply the very latest advances in every area of plastic surgery and ensure optimal outcomes. Purchase only the volumes you need or own the entire set, with the ability to search across all six volumes online!

Ultrasoundguided nerve blocks of the trunk and abdominal wall

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Publisher : Edra
ISBN 13 : 8821454908
Total Pages : 456 pages
Book Rating : 4.8/5 (214 download)

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Book Synopsis Ultrasoundguided nerve blocks of the trunk and abdominal wall by : Pierfrancesco Fusco

Download or read book Ultrasoundguided nerve blocks of the trunk and abdominal wall written by Pierfrancesco Fusco and published by Edra. This book was released on 2022-04-19T00:00:00+02:00 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to the introduction of ultrasound, the acquisition of new anatomy and sonoanatomy knowledge, as well as recent discoveries on the role of the fascia, regional anesthesia has undergone a process of "evolution-revolution" in the last decade and now is playing a key-role in surgery and postoperative pain management, allowing opioid-sparing or opioid-free strategies, in line with the ERAS pathway. With the contribution of the most prominent experts in the field, this book is a milestone for all professional figures involved in anesthesiology and pain therapy, thanks to the drawings, tables, flow charts, detailed anatomical and sono-anatomy pictures and clinical cases included in each chapter. The volume includes a chapter dedicated to the anatomy and function of fascia, a section on paraneuraxial block describing the paravertebral block and the ESP block in the countless fields of application, a section dedicated to the anterior thoracic blocks, a section on blocks of the anterior and posterior abdominal wall, a chapter on pediatric wall blocks, several chapters ranging from the neck band blocks, to the application and indication of the LIA and Wound infusion and an innovative chapter on the application of RA techniques in the COVID era. Videos are available on https://USguidedwallblocks.edizioniedra.com

Postoperative Analgesia Requirements After Propofol Anaesthesia with Intercostal Nerve Block Versus Sevofluorane and Opioids for Breast Cancer Surgery

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (125 download)

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Book Synopsis Postoperative Analgesia Requirements After Propofol Anaesthesia with Intercostal Nerve Block Versus Sevofluorane and Opioids for Breast Cancer Surgery by : V. López

Download or read book Postoperative Analgesia Requirements After Propofol Anaesthesia with Intercostal Nerve Block Versus Sevofluorane and Opioids for Breast Cancer Surgery written by V. López and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comparation of pectoral block/propofol anaesthesia versus sevofluorane/fentanyl anaesthesia for breast cancer surgeryBackground: Breast cancer surgery is one of the most frequently performed surgeries. This include tumorectomies and mastectomies with axillary clearance when needed. Even relatively minor breast surgery can be associated with significant postoperative pain. Thoracic epidural analgesia, paravertebral blocks and other regional techniques are commonly associated to general anaesthesia.Intercostal nerve block (PIB) is another alternative described as particularly useful for ambulatory patients Goal of study: We aim to demostrate that PIB provides better postoperative analgesia than general anaesthesia with sevofluorane and opioids (SAO) with less nausea and vomiting (PONV) and better patient comfort.Material & Methods: 20 women with diagnosis of breast cancer were randomized to recieve either PIB, with 20 ml chirocane 0.25% , performed under ultrasound guidance , or SAO anesthesia. Intraoperative fentanyl consumption, postoperative Visual analogic scale (VAS) pain scores at 1 and 24 h postoperative, postoperative fentanyle consumption, PONV scores and postsurgical hospital stay were recorded.Resultados: Patient demographics and duration of surgery were comparable for both groups(Fig I). PIB group had no need of opioids in the recovery room and presented significantly lower VAS pain scores and less PONV scores.There was no difference in hospital stay or intraoperative fentanyl(Fig 2).Discursion:Intercostal nerve block is easy to perform and is associated to less adverse events then epidural o paravertebral block,

Decision-Making in Orthopedic and Regional Anesthesiology

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Publisher : Cambridge University Press
ISBN 13 : 1107093546
Total Pages : 209 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Decision-Making in Orthopedic and Regional Anesthesiology by : Michael R. Anderson

Download or read book Decision-Making in Orthopedic and Regional Anesthesiology written by Michael R. Anderson and published by Cambridge University Press. This book was released on 2015-09-17 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: In light of evolving techniques and strategies for increasingly complex orthopedic procedures, this accessible guide to patient management outlines the considerations involved in selecting the most suitable anesthetic for both common and complex clinical scenarios. Chapters cover a multitude of clinical presentations and procedures, ranging from orthopedic trauma to total joint replacement, outpatient hand procedures and regional anesthetic placement in patients with pre-existing conditions. Each chapter discusses and evaluates multiple approaches, accompanied by a review of the current literature. Abundant case scenarios of patients undergoing orthopedic surgical or regional anesthesia provide a handy framework for specialists and consultants, as well as an invaluable guide for trainees in anesthesia, regional anesthesia and emergency medicine.

Anesthesia for Otolaryngologic Surgery

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Publisher : Cambridge University Press
ISBN 13 : 1139789481
Total Pages : 371 pages
Book Rating : 4.1/5 (397 download)

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Book Synopsis Anesthesia for Otolaryngologic Surgery by : Basem Abdelmalak

Download or read book Anesthesia for Otolaryngologic Surgery written by Basem Abdelmalak and published by Cambridge University Press. This book was released on 2012-10-18 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anesthesia for Otolaryngologic Surgery offers a comprehensive synopsis of the anesthetic management options for otolaryngologic and bronchoscopic procedures. Authored by world authorities in the fields of anesthesiology and otolaryngology, both theoretical concepts and practical issues are addressed in detail, providing literature-based evidence wherever available and offering expert clinical opinion where rigorous scientific evidence is lacking. A full chapter is dedicated to every common surgical ENT procedure, as well as less common procedures such as face transplantation. Clinical chapters are enriched with case descriptions, making the text applicable to everyday practice. Chapters are also enhanced by numerous illustrations and recommended anesthetic management plans, as well as hints and tips that draw on the authors' extensive experience. Comprehensively reviewing the whole field, Anesthesia for Otolaryngologic Surgery is an invaluable resource for every clinician involved in the care of ENT surgical patients, including anesthesiologists, otolaryngologists and pulmonologists.

Pain Management and the Opioid Epidemic

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Publisher : National Academies Press
ISBN 13 : 0309459575
Total Pages : 483 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Pain Management and the Opioid Epidemic by : National Academies of Sciences, Engineering, and Medicine

Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Acute Pain Management

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Publisher : Cambridge University Press
ISBN 13 : 0521874912
Total Pages : 729 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis Acute Pain Management by : Raymond S. Sinatra

Download or read book Acute Pain Management written by Raymond S. Sinatra and published by Cambridge University Press. This book was released on 2009-04-27 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides an overview of pain management useful to specialists as well as non-specialists, surgeons, and nursing staff.

Serratus Plane Block Impact in Pain and Opioid Uptake in Oncological Breast Surgery

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (116 download)

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Book Synopsis Serratus Plane Block Impact in Pain and Opioid Uptake in Oncological Breast Surgery by : Alma Casasempere Sanus

Download or read book Serratus Plane Block Impact in Pain and Opioid Uptake in Oncological Breast Surgery written by Alma Casasempere Sanus and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Serratus plane block impact in pain and opioid uptake in oncological breast surgery.Author(s): Casasempere Sanus A., Mazzinari G., Ortega Monzu00f3 J.M., Rovira Soriano L., Belaouchi M.,Esparza Miu00f1ana J.M.Institute(s): Hospital de Manises, Dept of Anaesthesiology, Manises, SpainBackground and Goal of Study: Regional anaesthesia is related with less incidence of cancer recurrence and less chronic pain developement. The paravertebral block is the most common regional technique in breast surgery, but it is difficult to perform and is not free from complications.Alternatively, ultrasound guided serratus plane block achieves complete analgesia of the axilomammary area by reaching the nerves between the pectoral and the serratus muscles (pectoral nerves, supraclavicular and long thoracic nerve) with a high security profile. The goal of this study is to evaluate the effect of the serratus plane block on opioids requirements during surgery and the immediate postoperative period as well as on the level of postoperative pain in oncological breast surgery.Materials and methods: We present a randomized intervention study (NCT02905149). Patients recruited undergoing oncological breast surgery are assigned to Control (intravenous opioid) or Serratus group. Every patient receives general anaesthesia with opioid analgesia according to the current hospital protocol. The block is performed with 20 ml 0'5% Levobupivacaine immediately after induction. In the postoperative period every patient is given a morphine PCA infusion pump which allows boluses of 1 mg every 15 min but no continuous infusion. Patients are followedu00adup during 24 h, asked for opioid consumption and pain estimated by VAS. We analyzed differences in opioiduptake in 24 h and pain VAS scores at set intervals (1,3,6,12,24 h).Results and discussion: We offer preliminary results from the data analysis of the first 11 recruited patients. The serratus plane block was effective in all cases. The cumulative opioids consumption over 24 h was higher in control group (35.2 mg, SD 5.96, 95% CI 21.92,48.48) than in Serratus group (21.5 mg, SD 3.41, 95% CI 13.89, 29.11). VAS scores for 24 h cumulative pain at rest and movement were higher in control than in Serratus group (AUCRcontrol 54.3, AUCRserratus 7.08, AUCMcontrol 75.9, AUCMserratus 13.3). Serratus group pain VAS scores were 2 or more points lower than the control group scores, both at rest and at movement.Conclusion(s): Serratus plane block provides adequate intraoperative and postoperative analgesia for oncological breast surgery. It is a simple, reproducible and safe technique, and may be an alternative to opioid analgesia or paravertebral block.