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Author :
Publisher :
ISBN 13 :
Total Pages : 2164 pages
Book Rating : 4.3/5 (91 download)
Download or read book LexisNexis Corporate Affiliations written by and published by . This book was released on 2008 with total page 2164 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Anupam Bishayee
Publisher : MDPI
ISBN 13 : 3038973106
Total Pages : 285 pages
Book Rating : 4.0/5 (389 download)
Download or read book Natural Products for Cancer Prevention and Therapy written by Anupam Bishayee and published by MDPI. This book was released on 2018-11-07 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Natural Products for Cancer Prevention and Therapy" that was published in Nutrients
Author : Patrizia Agostinis
Publisher : Springer Science & Business Media
ISBN 13 : 9400743513
Total Pages : 448 pages
Book Rating : 4.4/5 (7 download)
Download or read book Endoplasmic Reticulum Stress in Health and Disease written by Patrizia Agostinis and published by Springer Science & Business Media. This book was released on 2012-08-13 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Endoplasmic Reticulum (ER) is an organelle with extraordinary signaling and homeostatic functions. It is the organelle responsible for protein folding, maturation, quality control and trafficking of proteins destined for the plasma membrane or for secretion into the extracellular environment. Failure, overloading or malfunctioning of any of the signaling or quality control mechanisms occurring in the ER may provoke a stress condition known as ‘ER stress’. Accumulating evidence indicates that ER stress may dramatically perturb interactions between the cell and its environment, and contribute to the development of human diseases, ranging from metabolic diseases and cancer to neurodegenerative diseases, or impact therapeutic outcome. This book primarily focuses on the pathophysiology of ER stress. It introduces the molecular bases of ER stress, the emerging relevance of the ER-mitochondria cross-talk, the signaling pathways engaged and cellular responses to ER stress, including the adaptive Unfolded Protein Response (UPR), autophagy as well as cell death. Next the book addresses the role of ER stress in physiology and in the etiology of relevant pathological conditions, like carcinogenesis and inflammation, neurodegeneration and metabolic disease. The last chapter describes how ER stress pathways can be targeted for therapeutic benefit. Altogether, this book will provide the reader with an exhaustive view of ER stress biology and the latest insights in the role of ER stress in relevant human diseases.
Author : Yan Liu
Publisher : University of Washington Press
ISBN 13 : 0295749016
Total Pages : 278 pages
Book Rating : 4.2/5 (957 download)
Download or read book Healing with Poisons written by Yan Liu and published by University of Washington Press. This book was released on 2021-06-22 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Open access edition: DOI 10.6069/9780295749013 At first glance, medicine and poison might seem to be opposites. But in China’s formative era of pharmacy (200–800 CE), poisons were strategically employed as healing agents to cure everything from abdominal pain to epidemic disease. Healing with Poisons explores the ways physicians, religious figures, court officials, and laypersons used toxic substances to both relieve acute illnesses and enhance life. It illustrates how the Chinese concept of du—a word carrying a core meaning of “potency”—led practitioners to devise a variety of methods to transform dangerous poisons into effective medicines. Recounting scandals and controversies involving poisons from the Era of Division to the Tang, historian Yan Liu considers how the concept of du was central to how the people of medieval China perceived both their bodies and the body politic. He also examines the wide range of toxic minerals, plants, and animal products used in classical Chinese pharmacy, including everything from the herb aconite to the popular recreational drug Five-Stone Powder. By recovering alternative modes of understanding wellness and the body’s interaction with foreign substances, this study cautions against arbitrary classifications and exemplifies the importance of paying attention to the technical, political, and cultural conditions in which substances become truly meaningful. Healing with Poisons is freely available in an open access edition thanks to TOME (Toward an Open Monograph Ecosystem) and the generous support of the University of Buffalo.
Author : Malcolm Lader
Publisher : Springer Science & Business Media
ISBN 13 : 0387276823
Total Pages : 319 pages
Book Rating : 4.3/5 (872 download)
Download or read book Sleep and Sleep Disorders: written by Malcolm Lader and published by Springer Science & Business Media. This book was released on 2009-11-06 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many recent discoveries in both laboratory and clinical settings have greatly increased our understanding of sleep medicine and the relevant psychopharmacology. This timely book serves to present updated information about the neuropsychopharmacology of sleep as this field enters mainstream psychiatry, neurology and medicine This volume has assembled articles that summarize and review carefully, a chosen selection of the latest discoveries concerning sleep medicine, sleep physiology and sleep pharmacology. Outstanding contributions have been sought from acknowledged experts in their respective fields. The goal of the volume is to present the more recent developments and advances in the fields of sleep and neuropsychopharmacology, as well as to provide a context for considering them both in depth and from multidisciplinary perspectives. This volume brings together the collective expertise of clinicians and basic researchers who represent a range of interests in neuroscience, neuropharmacology, sleep physiology, and biological rhythms. Presenting a thoughtful balance of basic experimental and clinical facts and viewpoints, this book will serve as a foundation for understanding, and ultimately treating, sleep disorders.
Author : Adam Jabłoński
Publisher : MDPI
ISBN 13 : 3039212338
Total Pages : 396 pages
Book Rating : 4.0/5 (392 download)
Download or read book Trust Management written by Adam Jabłoński and published by MDPI. This book was released on 2019-07-16 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: element of relationships between entities, but, above all, it positively influences the building of an organization's intellectual capital. This capital can be defined in different ways, but its definition always references elements that determine the potential of sustainable organizations, often in human, social, relational, organizational, and innovation dimensions. Trust is increasingly becoming the key determinant of this capital (Kożuch, Lenart-Gansiniec, 2017). Trust also has a number of different definitions. However, the basis of many of these definitions is the building of relationships focused on developing some kind of individual or inter-organizational link. Organizational trust is a complicated concept, and it is the basis of all organized activities performed by people in the organization, largely because trust is needed to develop relationships with integrity and commitment. Thus, it is interesting to study the relationship between trust and the building of the intellectual capital of sustainable organizations. Indeed, intellectual capital plays a special role here. It is a guide and a platform for achieving not only a competitive advantage for the sustainable organization, but also a source of value creation in the short and long term. Thus, this strategic hybrid, composed of a business model, strategy, and business processes, is favorable to the development of intellectual capital (Jabłoński 2017). Trust is an element that ties this capital to relationships in business. Moreover, it has an integrated character (R.C. Mayer, J. H. Davis, F. D. Schoorman 1995). Assuming that, nowadays, the network paradigm is becoming increasingly important, it is worth asking how the mechanism of building trust-based intellectual capital in a sustainable organization functions as its key asset in the network environment.
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Publisher :
ISBN 13 :
Total Pages : 2250 pages
Book Rating : 4.3/5 (555 download)
Download or read book Mergent International News Reports written by and published by . This book was released on 2008-05 with total page 2250 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Rob van Tulder
Publisher : Emerald Group Publishing
ISBN 13 : 1787563278
Total Pages : 441 pages
Book Rating : 4.7/5 (875 download)
Download or read book International Business in the Information and Digital Age written by Rob van Tulder and published by Emerald Group Publishing. This book was released on 2018-11-16 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: The information and digital age is shaped by a small number of multinational enterprises from a limited number of countries. This volume covers the latest insight from the International Business discipline on prevailing trends in business model evolution. It also discusses critical issues of regulation in the new information and digital space.
Author : Julio Villena
Publisher : Frontiers Media SA
ISBN 13 : 2889453820
Total Pages : 309 pages
Book Rating : 4.8/5 (894 download)
Download or read book Immunobiotics: Interactions of Beneficial Microbes with the Immune System written by Julio Villena and published by Frontiers Media SA. This book was released on 2018-01-26 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term “immunobiotics” has been proposed to define microbial strains able to beneficially regulate the mucosal immune system. Research in immunobiotics has significantly evolved as researchers employed cutting-edge technologies to investigate the complex interactions of these beneficial microorganisms with the immune system. During the last decade, our understanding of immunobiotics-host interaction was profoundly transformed by the discovery of microbial molecules and host receptors involved in the modulation of gut associated immune system, as well as the systemic and distant mucosal immune systems. In recent years, there has been a substantial increase in the number of reports describing the beneficial effects of immunobiotics in diseases such as intestinal and respiratory infections, allergy, inflammatory bowel disease, obesity, immunosuppression, and several other immune-mediated conditions. Evidence is also emerging of immunobiotics related molecules with immunomodulatory functions leading to the production of pharmabiotics, which may positively influence human or animal health. Therefore, research in immunobiotics continue to contribute not only to food but also medical and pharmaceutical fields. The compilation of research articles included in this ebook should help reader to have an overview of the recent advances in immunobiotics.
Author : Lixin Zhang
Publisher : Springer Science & Business Media
ISBN 13 : 1592599761
Total Pages : 380 pages
Book Rating : 4.5/5 (925 download)
Download or read book Natural Products written by Lixin Zhang and published by Springer Science & Business Media. This book was released on 2007-11-17 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discoveries, to microbial diversity, to specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.
Author : John S. Dick
Publisher : Hanser Pub Incorporated
ISBN 13 : 9781569905371
Total Pages : 582 pages
Book Rating : 4.9/5 (53 download)
Download or read book Raw Materials Supply Chain for Rubber Products written by John S. Dick and published by Hanser Pub Incorporated. This book was released on 2014-06-30 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rubber industry is a vital part of the world economy. In this age of constantly changing economics and raw material "shortages of the week," this book should help the reader understand the overall technical and economic problems that are emerging which are beginning to affect the overall availability of many raw materials, chemical intermediates and final rubber products on the world scene. This book is truly unique in that it is the only one that traces all the important organic and inorganic synthesis routes for the manufacture of synthetic rubbers, various fillers, plasticizers, oils, curatives, antidegradants, adhesion promoters, flame retardants, tackifiers, and blowing agents through their respective intermediates to the base raw materials from earth extractions and agriculture.
Author : Guoqiao Li
Publisher : Academic Press
ISBN 13 : 0128132116
Total Pages : 738 pages
Book Rating : 4.1/5 (281 download)
Download or read book Artemisinin-Based and Other Antimalarials written by Guoqiao Li and published by Academic Press. This book was released on 2017-11-28 with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable reference for students and researchers in the fields of scientific history, medicine, pharmaceutical science, chemistry, pharmacology and toxicology. - Presents details of all stages of drug development, including in vitro experiment, animal exploratory studies, animal tests for toxicity, safety and efficacy followed by stages I, II, III and IV, safety and efficacy in human volunteers and patients with malaria - Provides many physical-chemical laboratory procedures, such as NMR, MS, HPLC and X-ray diffraction used in drug development - Includes practical methodology of clinical trials from many research centers and countries to demonstrate the importance of this discovery
Download or read book Space Science in the Twenty-first Century written by and published by . This book was released on 1988 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Hildebert Wagner
Publisher : Springer Science & Business Media
ISBN 13 : 3709107636
Total Pages : 1008 pages
Book Rating : 4.7/5 (91 download)
Download or read book Chromatographic Fingerprint Analysis of Herbal Medicines written by Hildebert Wagner and published by Springer Science & Business Media. This book was released on 2011-11-24 with total page 1008 pages. Available in PDF, EPUB and Kindle. Book excerpt: This manual, to be published in two volumes, provides a condensed overview of the analytical investigation of 80 Chinese Herbal Drugs which are most frequently in use. Thin layer chromatographic-, high pressure liquid chromatographic- and gas chromatographic-fingerprint analytical techniques allow the detection of all main low-molecular constituents of a plant drug and even single constituents can be visualized. Analytical results thereof are shown in numerous color figures. The quality proof of the investigation meets the standard of the European Drug Regulatory Authority. Furthermore, this volume gives a detailed description of the analytical methods used for several drugs. Bioactive constituents, pharmacological and biological activities of several single herbal drugs as well as their therapeutic applications are discussed.
Author :
Publisher : Routledge
ISBN 13 : 9781857430660
Total Pages : 696 pages
Book Rating : 4.4/5 (36 download)
Download or read book Western Europe 2000 written by and published by Routledge. This book was released on 2000 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 40 acknowledged experts provide insight into all countries of the region and offer scholarly examinations of the area's political, economic and social background. Separate chapters for every country provide details of geography, recent history and the economy.
Author : Jacob T. Bjerrum
Publisher : Humana
ISBN 13 : 9781493923762
Total Pages : 0 pages
Book Rating : 4.9/5 (237 download)
Download or read book Metabonomics written by Jacob T. Bjerrum and published by Humana. This book was released on 2015-02-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume on metabonomics provides detailed information on the procedures involved in nuclear magnetic resonance (NMR) spectroscopy, gas chromatography-mass spectrometry (GS-MS), liquid chromatography-mass spectrometry (LC-MS), and capillary electrophoresis-mass spectrometry (CE-MS). Chapters focus on technologies and chemometrics, generation of metabonomics data, extraction of meaningful information from data, drug development, toxicology, diagnostics, and describing metabonomics as an essential part of systems biology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Author :
Publisher :
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.:/5 (44 download)
Download or read book The Medical Classic of the Yellow Emperor written by and published by . This book was released on 2001 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compiled 2,000 years ago, The Medical Classic of the Yellow Emperor is the oldest extant classic of the field and serves as the theoretical basis of traditional Chinese medicine.
