Company Profiles Molecular Targeting Technologies Inc

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Molecular Targeted Radiosensitizers

Author : Henning Willers
Publisher : Springer Nature
ISBN 13 : 3030497011
Total Pages : 370 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Molecular Targeted Radiosensitizers by : Henning Willers

Download or read book Molecular Targeted Radiosensitizers written by Henning Willers and published by Springer Nature. This book was released on 2020-08-10 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Targeted Radiosensitizers: Opportunities and Challenges provides the reader with a comprehensive review of key pre-clinical research components required to identify effective radiosensitizing drugs. The book features discussions on the mechanisms and markers of clinical radioresistance, pre-clinical screening of targeted radiosensitizers, 3D radiation biology for studying radiosensitizers, in vivo determinations of local tumor control, genetically engineered mouse models for studying radiosensitizers, targeting the DNA damage response for radiosensitization, targeting tumor metabolism to overcome radioresistance, radiosensitizers in the era of immuno-oncology, and more. Additionally, the book features discussions on high-throughput drug screening, predictive biomarkers, pre-clinical tumor models, and the influence of the tumor microenvironment and the immune system, with a specific focus on the challenges radiation oncologists and medical oncologists currently face in testing radiosensitizers in human cancers. Edited by two acclaimed experts in radiation biology and radiosensitizers, with thirteen chapters contributed by experts, this new volume presents an in-depth look at current developments within a rapidly moving field, with a look at where the field will be heading and providing comprehensive insight into the framework of targeted radiosensitzer development. Essential reading for investigators in cancer research and radiation biology.

Organelle and Molecular Targeting

Author : Lara Scheherazade Milane
Publisher : CRC Press
ISBN 13 : 1000505936
Total Pages : 511 pages
Book Rating : 4.0/5 (5 download)

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Book Synopsis Organelle and Molecular Targeting by : Lara Scheherazade Milane

Download or read book Organelle and Molecular Targeting written by Lara Scheherazade Milane and published by CRC Press. This book was released on 2021-12-27 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: We have surpassed the omics era and are truly in the Age of Molecular Therapeutics. The fast-paced development of SARS-CoV-2 vaccines, such as the mRNA vaccines encoding the viral spike protein, demonstrated the need for and capability of molecular therapy and nanotechnology-based solutions for drug delivery. In record speed, the SARS-CoV-2 viral RNA genome was sequenced and shared with the scientific community, allowing the rapid design of molecular therapeutics. The mRNA vaccines exploit the host cell endoplasmic reticulum to produce viral spike proteins for antigen presentation and recognition by the innate and adaptive immune system. Lipid nanoparticles enable the delivery of the fragile, degradation-sensitive nucleic acid payloads. Molecular-based therapeutics and nanotechnology solutions continue to drive the scientific and medical response to the COVID-19 pandemic as new mRNA, DNA, and protein-based vaccines are developed and approved and the emergency use approved vaccines are rapidly manufactured and distributed throughout the globe. The need for molecular therapies and drug delivery solutions is clear, and as these therapies progress and become more specialized there will be important advancements in organelle targeting. For example, using organelle targeting to direct lipid nanoparticles with mRNA payloads to the endoplasmic reticulum would increase the efficacy of mRNA vaccines, reducing the required dose and therefore the biomanufacturing demand. Likewise, improving the delivery of DNA therapeutics to the nucleus would improve efficacy. Organelles and molecules have always been drug targets, but until recently we have not had the tools or capability to design and develop such highly specific therapeutics. Organelle targeting has far-reaching implications. For example, mitochondria are central to both energy production and intrinsic apoptosis. Effectively targeting and manipulating mitochondria has therapeutic applications for diseases such as myopathies, cancer, neurodegeneration, progerias, diabetes, and the natural aging process. The SARS-CoV-2 vaccines that exploit the endoplasmic reticulum (for mRNA vaccines) and the nucleic translational process (DNA vaccines) attest to the need for organelle and molecular therapeutics. This book covers the status, demand, and future of organelle- and molecularly targeted therapeutics that are critical to the advancement of modern medicine. Organelle and molecular targeting is the drug design and drug delivery approach of today and the future; understanding this approach is essential for students, scientists, and clinicians contributing to modern medicine.

Molecular Imaging

Author : Brian D. Ross
Publisher : Academic Press
ISBN 13 : 0128163879
Total Pages : 1872 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Molecular Imaging by : Brian D. Ross

Download or read book Molecular Imaging written by Brian D. Ross and published by Academic Press. This book was released on 2021-08-03 with total page 1872 pages. Available in PDF, EPUB and Kindle. Book excerpt: The detection and measurement of the dynamic regulation and interactions of cells and proteins within the living cell are critical to the understanding of cellular biology and pathophysiology. The multidisciplinary field of molecular imaging of living subjects continues to expand with dramatic advances in chemistry, molecular biology, therapeutics, engineering, medical physics and biomedical applications. Molecular Imaging: Principles and Practice, Volumes 1 and 2, Second Edition provides the first point of entry for physicians, scientists, and practitioners. This authoritative reference book provides a comprehensible overview along with in-depth presentation of molecular imaging concepts, technologies and applications making it the foremost source for both established and new investigators, collaborators, students and anyone interested in this exciting and important field. - The most authoritative and comprehensive resource available in the molecular-imaging field, written by over 170 of the leading scientists from around the world who have evaluated and summarized the most important methods, principles, technologies and data - Concepts illustrated with over 600 color figures and molecular-imaging examples - Chapters/topics include, artificial intelligence and machine learning, use of online social media, virtual and augmented reality, optogenetics, FDA regulatory process of imaging agents and devices, emerging instrumentation, MR elastography, MR fingerprinting, operational radiation safety, multiscale imaging and uses in drug development - This edition is packed with innovative science, including theranostics, light sheet fluorescence microscopy, (LSFM), mass spectrometry imaging, combining in vitro and in vivo diagnostics, Raman imaging, along with molecular and functional imaging applications - Valuable applications of molecular imaging in pediatrics, oncology, autoimmune, cardiovascular and CNS diseases are also presented - This resource helps integrate diverse multidisciplinary concepts associated with molecular imaging to provide readers with an improved understanding of current and future applications

Small Business Innovation Research Program (SBIR)

Author : United States. Congress. House. Committee on Small Business. Subcommittee on Government Programs and Oversight
Publisher :
ISBN 13 :
Total Pages : 260 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Small Business Innovation Research Program (SBIR) by : United States. Congress. House. Committee on Small Business. Subcommittee on Government Programs and Oversight

Download or read book Small Business Innovation Research Program (SBIR) written by United States. Congress. House. Committee on Small Business. Subcommittee on Government Programs and Oversight and published by . This book was released on 1998 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drug-Diagnostics Co-Development in Oncology

Author : Jan Trøst Jørgensen
Publisher : Frontiers E-books
ISBN 13 : 2889193322
Total Pages : 112 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Drug-Diagnostics Co-Development in Oncology by : Jan Trøst Jørgensen

Download or read book Drug-Diagnostics Co-Development in Oncology written by Jan Trøst Jørgensen and published by Frontiers E-books. This book was released on 2014-11-07 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: The idea of combining drugs and diagnostics in oncology is not new. When the selective estrogen receptor modulator tamoxifen was developed in the 1970’s for the treatment of breast cancer a positive correlation between receptor status and treatment outcome was found. As a result of this research, it was suggested to use the estrogen-receptor assay as a diagnostic test for selection of patients for tamoxifen treatment. Despite this suggestion was put forward nearly 40 years ago the adaptation of the drug-diagnostic co-development model has been relatively slow and it is only within the last decade that it has gained more widespread acceptance. The parallel development of the monoclonal antibody trastuzumab (Herceptin®, Roche/Genentech) and the immunohistochemistry assay for HER2 protein overexpression (HercepTest™, Dako) seems to have served as an inspiration to a number of stakeholders such as pharma and diagnostic companies, regulatory agencies, and academia. In recent years we have seen an increasing number of oncology drug development projects that have taken advantage of the drug-diagnostic co-development model, as outline below. Most of the new targeted anti-cancer drugs that have been introduced in recent years, such as BRAF-, ALK-, EGFR- and HER2-inhibitors, are more or less all a product of the drugdiagnostic co-development model. These drugs have shown remarkable high response rates in selected groups of patients within cancer diseases with great unmet medical needs. This Research Topic on Drug-Diagnostic Co-Development in Oncology aims to provide you with an insight into some of the diverse activities that constitute this new research area.

Guide to NIST

Author : National Institute of Standards and Technology (U.S.)
Publisher :
ISBN 13 :
Total Pages : 178 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Guide to NIST by : National Institute of Standards and Technology (U.S.)

Download or read book Guide to NIST written by National Institute of Standards and Technology (U.S.) and published by . This book was released on 1996 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nanobiosensors

Author : Aiguo Wu
Publisher : John Wiley & Sons
ISBN 13 : 3527345108
Total Pages : 412 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Nanobiosensors by : Aiguo Wu

Download or read book Nanobiosensors written by Aiguo Wu and published by John Wiley & Sons. This book was released on 2020-06-02 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Containing cutting edge research on the hot topic of nanobiosensor, this book will become highly read Biosensor research has recently re-emerged as most vibrant area in recent years particularly after the advent of novel nanomaterials of multidimensional features and compositions. Nanomaterials of different types and striking properties have played a positive role in giving the boost and accelerated pace to biosensors development technology. Nanobiosensors - From Design to Applications covers several aspects of biosensors beginning from the basic concepts to advanced level research. It will help to bridge the gap between various aspects of biosensors development technology and applications. It covers biosensors related material in broad spectrum such as basic concepts, biosensors & their classification, biomarkers & their role in biosensors, nanostructures-based biosensors, applications of biosensors in human diseases, drug detection, toxins, and smart phone based biosensors. Nanobiosensors - From Design to Applications will prove a source of inspiration for research on biosensors, their local level development and consequently using for practical application in different industries such as food, biomedical diagnosis, pharmaceutics, agriculture, drug discovery, forensics, etc. * Discusses the latest technology and advances in the field of nanobiosensors and their applications in human diseases, drug detection, toxins * Offers a broad and comprehensive view of cutting-edge research on advanced materials such as carbon materials, nitride based nanomaterials, metal and metal oxide based nanomaterials for the fast-developing nanobiosensors research * Goes to a wide scientific and industry audience Nanobiosensors - From Design to Applications is a resource for polymer chemists, spectroscopists, materials scientists, physical chemists, surface chemists, and surface physicists.

Directory of Biotechnology Companies

Author :
Publisher :
ISBN 13 :
Total Pages : 852 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Directory of Biotechnology Companies by :

Download or read book Directory of Biotechnology Companies written by and published by . This book was released on 2000 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Recent Advances in Molecular Targets for Drug Discovery and Delivery in Tumor

Author : Sanjun Shi
Publisher : Frontiers Media SA
ISBN 13 : 2889761134
Total Pages : 361 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Recent Advances in Molecular Targets for Drug Discovery and Delivery in Tumor by : Sanjun Shi

Download or read book Recent Advances in Molecular Targets for Drug Discovery and Delivery in Tumor written by Sanjun Shi and published by Frontiers Media SA. This book was released on 2022-05-05 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt:

F&S Index United States

Author :
Publisher :
ISBN 13 :
Total Pages : 632 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis F&S Index United States by :

Download or read book F&S Index United States written by and published by . This book was released on 1997 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pharmacogenomics

Author : Julio Licinio
Publisher : John Wiley & Sons
ISBN 13 : 3527616306
Total Pages : 599 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Pharmacogenomics by : Julio Licinio

Download or read book Pharmacogenomics written by Julio Licinio and published by John Wiley & Sons. This book was released on 2009-07-30 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work represents the first comprehensive publication in the innovative field of pharmacogenomics, a field which is set to revolutionize pharmaceutical research. In addition to renowned editors, the list of contributors is a "who-is-who" in the field. Broad coverage of all aspects of pharmacogenomics with a full presentation of applications to disease conditions is featured. Anyone involved in pharmaceutical research and drug development needs this book to keep up with this new and revolutionary approach

Targeting Pancreatic Cancer: Strategies and Hopes

Author : Kanjoormana Aryan Manu
Publisher : Frontiers Media SA
ISBN 13 : 2889749916
Total Pages : 166 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Targeting Pancreatic Cancer: Strategies and Hopes by : Kanjoormana Aryan Manu

Download or read book Targeting Pancreatic Cancer: Strategies and Hopes written by Kanjoormana Aryan Manu and published by Frontiers Media SA. This book was released on 2022-04-25 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Nuclear Medicine

Author : L.E. Feinendegen
Publisher : Springer Science & Business Media
ISBN 13 : 364255539X
Total Pages : 795 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Molecular Nuclear Medicine by : L.E. Feinendegen

Download or read book Molecular Nuclear Medicine written by L.E. Feinendegen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 795 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical transparency of the human body is at the doorstep of advanced technology. Toward this goal the book describes relevant isotopic tracer techniques of nuclear medicine. It deals with quantitatively measuring in vivo biochemical reactions as they occur within homeostatic circuits under control by genes and protein interactions. The text indicates how nuclear medicine can aid clinical researchers and practitioners, human geneticists and pharmacologists in understanding (and affecting) gene-phenotype relationships. Experts give background, techniques and examples in an interdisciplinary approach to regional imaging and in vitro analyses of biochemical reactions.

Thomas Register of American Manufacturers and Thomas Register Catalog File

Author :
Publisher :
ISBN 13 :
Total Pages : 2198 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Thomas Register of American Manufacturers and Thomas Register Catalog File by :

Download or read book Thomas Register of American Manufacturers and Thomas Register Catalog File written by and published by . This book was released on 2002 with total page 2198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1970-71 includes manufacturers' catalogs.

Nanomedicine

Author :
Publisher : Elsevier
ISBN 13 : 0857096443
Total Pages : 705 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Nanomedicine by :

Download or read book Nanomedicine written by and published by Elsevier. This book was released on 2012-10-19 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology is at the forefront of advances in medicine. Nanomedicine: Technologies and applications provides an important review of this exciting technology and its growing range of applications. After an introduction to nanomedicine, part one discusses key materials and their properties, including nanocrystalline metals and alloys, nanoporous gold and hydroxyapatite coatings. Part two goes on to review nanomedicine for therapeutics and imaging, before nanomedicine for soft tissue engineering is discussed in part three, including organ regeneration, skin grafts, nanotubes and self-assembled nanomaterials. Finally, nanomedicine for bone and cartilage tissue engineering is the focus of part four, with electrically active biocomposites as smart scaffolds investigated, as is cartilage and bone tissue engineering, regeneration and replacement. With its distinguished editor and international team of expert contributors, Nanomedicine: Technologies and applications is an indispensable guide for all those involved in the research, development and application of this exciting technology, whilst providing a comprehensive introduction for students and academics interested in this field. Provides an important review of nanomedicine technology and its growing range of applications Discusses key nanomedicine materials and their properties, including nanocrystalline metals and alloys, nanoporous gold and hydroxyapatite coatings Reviews nanomedicine for therapeutics and imaging and nanomedicine for soft tissue engineering

Analytical Techniques in Combinatorial Chemistry

Author : Michael E. Swartz
Publisher : CRC Press
ISBN 13 : 9780203909966
Total Pages : 320 pages
Book Rating : 4.9/5 (99 download)

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Book Synopsis Analytical Techniques in Combinatorial Chemistry by : Michael E. Swartz

Download or read book Analytical Techniques in Combinatorial Chemistry written by Michael E. Swartz and published by CRC Press. This book was released on 2000-02-18 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the necessary tools for developing methods and analyzing results in the drug discovery process, and supports documenting and managing the process in a combinatorial setting. It describes the chromatographic and spectroscopic techniques used to generate chemical and molecular diversity in new compounds, focusing on applications

Beating Melanoma

Author : Steven Q. Wang
Publisher : JHU Press
ISBN 13 : 1421449498
Total Pages : 184 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis Beating Melanoma by : Steven Q. Wang

Download or read book Beating Melanoma written by Steven Q. Wang and published by JHU Press. This book was released on 2024-05-21 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now completely updated! The essential guide for people with melanoma. In Beating Melanoma, world-renowned skin cancer expert Dr. Steven Q. Wang provides an indispensable guide for those diagnosed with melanoma. Now in its second edition and completely revised, this practical guide offers up-to-date research on the diagnosis, treatment, and prevention of melanoma, and a readable narrative that demystifies everything from the pathology report to the stages of cancer. This new edition features updated information on new immunotherapies and targeted therapies, as well as access to online interviews with more than 25 leading melanoma experts from fields including dermatology, medical oncology, surgical oncology, radiation oncology, dermatopathology, and genetics. Beating Melanoma approaches the disease in two phases. First, Dr. Wang lays out a step-by-step guide for approaching the "mad rush" phase—an intense and stressful period from diagnosis to completing initial treatment. Dr. Wang's calm guidance helps readers through this critical time with an easy-to-understand plan for ensuring optimal treatment and survival outcomes. Once the mad rush phase is over, the "marathon phase" begins—life resumes its normal shape but with lingering concerns about new melanoma and metastases. Here Dr. Wang addresses common questions about prevention and prognosis. This guide is a thorough, comforting, and informative book for melanoma patients and their families.