Community Series in Resident Memory T Cells: Guardians of the Balance of Local Immunity and Pathology, Volume II

Download Community Series in Resident Memory T Cells: Guardians of the Balance of Local Immunity and Pathology, Volume II PDF Online Free

Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832550525
Total Pages : 136 pages
Book Rating : 4.8/5 (325 download)

DOWNLOAD NOW!


Book Synopsis Community Series in Resident Memory T Cells: Guardians of the Balance of Local Immunity and Pathology, Volume II by : Nick P. Goplen

Download or read book Community Series in Resident Memory T Cells: Guardians of the Balance of Local Immunity and Pathology, Volume II written by Nick P. Goplen and published by Frontiers Media SA. This book was released on 2024-06-20 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: As we learn more about the intricacies of immune interactions, the goalposts of ideal vaccination strategies change. It has become apparent that for many pathogens, immunizations should seek to optimize lymphocyte-mediated protection at their portals of entry, which is not likely to be accomplished with current intramuscular jabs. However, there are increased reports suggesting resident memory CD4 and CD8 T cells may, or indeed do, cause pathologies in the lung, gut, skin, pancreas, CNS, and adipose tissue. This is following chronic infection, immunization, or sensitization and it is becoming clearer that protective immunity ought to be finely balanced with the pathogenic capacity of the resident cells providing the immunity. Alternatively, in instances like asthma or inflammatory bowel disease (IBD) where the bulk of resident CD4 or CD8T cells’ pathogenic capacity is not restrained, understanding the mechanisms of escape from immune regulation may be key. Thus we are interested in soliciting works that seek to provide a deeper mechanistic understanding of the balance of immunity and pathology that local resident memory T cells must successfully display in order to build upon the existing dogma regarding ideal vaccination strategies.

Resident Memory T Cells: Guardians of the Balance of Local Immunity and Pathology

Download Resident Memory T Cells: Guardians of the Balance of Local Immunity and Pathology PDF Online Free

Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889715485
Total Pages : 124 pages
Book Rating : 4.8/5 (897 download)

DOWNLOAD NOW!


Book Synopsis Resident Memory T Cells: Guardians of the Balance of Local Immunity and Pathology by : Nick P. Goplen

Download or read book Resident Memory T Cells: Guardians of the Balance of Local Immunity and Pathology written by Nick P. Goplen and published by Frontiers Media SA. This book was released on 2021-10-25 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Differentiation, Tissue Adaptation and Function of Memory T Cells

Download Differentiation, Tissue Adaptation and Function of Memory T Cells PDF Online Free

Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889637956
Total Pages : 171 pages
Book Rating : 4.8/5 (896 download)

DOWNLOAD NOW!


Book Synopsis Differentiation, Tissue Adaptation and Function of Memory T Cells by : Weiguo Cui

Download or read book Differentiation, Tissue Adaptation and Function of Memory T Cells written by Weiguo Cui and published by Frontiers Media SA. This book was released on 2020-06-16 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: Upon antigen encounter, naïve T cells differentiate into (i) effectors that combat infected or malignant cells, and at later time points, into (ii) memory cells that provide long-lasting immunity. This differentiation process allows some T cells to leave the confines of secondary lymphoid organs and to enter peripheral tissues in search of pathogens or tumor cells. These different environments pose specific challenges for effector and memory T cells to maintain homeostasis. T cells directed into the lungs are likely to encounter higher levels of oxygen, but lower amounts of nutrients than those directed into the intestinal epithelium. In addition to oxygen tension and nutrient concentrations, other key factors, such as the commensal flora and stromal components, create unique conditions that require tissue-specific adaptations of T cells. These steady state conditions can dramatically change during infection when inflammatory mediators and T cell growth factors are released, requiring the immediate response of T cells. The gradual changes imposed by growing tumors can also be challenging for T cells due to competition with rapidly cycling tumor cells that deplete essential resources of oxygen and glucose. The strategies that T cells employ to respond to the diverse cues from their surroundings are the focus of current research. It appears that next to circulating memory T cells that are confined to the circulation and those that survey all of the peripheral tissues, dedicated populations of resident memory T cells exist that can optimally adapt to the local circumstances within each tissue. Restrictions on the metabolic requirements of T cells residing in tumor tissue have been found to directly impact on effector functions such as cytokine production. The fundamental principles of how the machinery of T cells can translate local cues into tissue-specific differentiation processes are fascinating and warrant further investigation.

Disease Control Priorities, Third Edition (Volume 6)

Download Disease Control Priorities, Third Edition (Volume 6) PDF Online Free

Author :
Publisher : World Bank Publications
ISBN 13 : 1464805253
Total Pages : 1027 pages
Book Rating : 4.4/5 (648 download)

DOWNLOAD NOW!


Book Synopsis Disease Control Priorities, Third Edition (Volume 6) by : King K. Holmes

Download or read book Disease Control Priorities, Third Edition (Volume 6) written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

The CMS Hospital Conditions of Participation and Interpretive Guidelines

Download The CMS Hospital Conditions of Participation and Interpretive Guidelines PDF Online Free

Author :
Publisher :
ISBN 13 : 9781683086857
Total Pages : 546 pages
Book Rating : 4.0/5 (868 download)

DOWNLOAD NOW!


Book Synopsis The CMS Hospital Conditions of Participation and Interpretive Guidelines by :

Download or read book The CMS Hospital Conditions of Participation and Interpretive Guidelines written by and published by . This book was released on 2017-11-27 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: In addition to reprinting the PDF of the CMS CoPs and Interpretive Guidelines, we include key Survey and Certification memos that CMS has issued to announced changes to the emergency preparedness final rule, fire and smoke door annual testing requirements, survey team composition and investigation of complaints, infection control screenings, and legionella risk reduction.

Oral Health in America

Download Oral Health in America PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 32 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Oral Health in America by :

Download or read book Oral Health in America written by and published by . This book was released on 2000 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunology for Surgeons

Download Immunology for Surgeons PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9781852334826
Total Pages : 486 pages
Book Rating : 4.3/5 (348 download)

DOWNLOAD NOW!


Book Synopsis Immunology for Surgeons by : Andrew P. Zbar

Download or read book Immunology for Surgeons written by Andrew P. Zbar and published by Springer Science & Business Media. This book was released on 2002-02-20 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: An understanding of the complex workings of the immune system is essential for all surgeons. Immune responses play a crucial part in the way human body reacts to infection and trauma. Immunology for Surgeons contains a high-level discussion of this difficult clinical area. The text looks at tumor immunobiology and immunotherapy as well as the worldwide results of various clinical trials. The topics discussed focus on relevant immunological and molecular biological trends for future treatment of complex surgical disease. The main objective of the text is to render a difficult area accessible for the postgraduate surgical trainee and established surgeon who is interested in immunology.

Psychic Self-Defense

Download Psychic Self-Defense PDF Online Free

Author :
Publisher : Phoemixx Classics Ebooks
ISBN 13 : 3986775390
Total Pages : 200 pages
Book Rating : 4.9/5 (867 download)

DOWNLOAD NOW!


Book Synopsis Psychic Self-Defense by : Dion Fortune

Download or read book Psychic Self-Defense written by Dion Fortune and published by Phoemixx Classics Ebooks. This book was released on 2021-12-12 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychic Self-Defense Dion Fortune - "Psychic Self-Defense" is one of the best guides to detection and defence against psychic attack from one of the leading occult writers of the 20th century. After finding herself the subject of a powerful psychic attack in the 1930's, famed British occultist Dion Fortune wrote this detailed instruction manual on protecting oneself from paranormal attack. This classic psychic self-defence guide explains how to understand the signs of a psychic attack, vampirism, hauntings, and methods of defence. Everything you need to know about the methods, motives, and physical aspects of a psychic attack and how to overcome it is here, along with a look at the role psychic elements play in mental illness and how to recognise them.

Essential Immunology for Surgeons

Download Essential Immunology for Surgeons PDF Online Free

Author :
Publisher : Oxford University Press, USA
ISBN 13 : 019958687X
Total Pages : 547 pages
Book Rating : 4.1/5 (995 download)

DOWNLOAD NOW!


Book Synopsis Essential Immunology for Surgeons by : Oleg Eremin

Download or read book Essential Immunology for Surgeons written by Oleg Eremin and published by Oxford University Press, USA. This book was released on 2011-04-28 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing the necessary foundation for a critical understanding of this rapidly expanding area of biological science that underpins and explains the modern concepts of a wide range of diseases and conditions, this book gives a concise, readable, and up-to-date account of immunology in general and its translation into key areas of clinical practice.

The Ethics of Research Involving Animals

Download The Ethics of Research Involving Animals PDF Online Free

Author :
Publisher :
ISBN 13 : 9781904384106
Total Pages : 335 pages
Book Rating : 4.3/5 (841 download)

DOWNLOAD NOW!


Book Synopsis The Ethics of Research Involving Animals by :

Download or read book The Ethics of Research Involving Animals written by and published by . This book was released on 2005-01-01 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: A report of the Nuffield Council on Bioethics working party investigating the ethical issues of research involving animals.

Immunology of Aging

Download Immunology of Aging PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

DOWNLOAD NOW!


Book Synopsis Immunology of Aging by : Sudhir Gupta

Download or read book Immunology of Aging written by Sudhir Gupta and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Instructions to Surveyors

Download Instructions to Surveyors PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 98 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Instructions to Surveyors by : Great Britain. Board of Trade

Download or read book Instructions to Surveyors written by Great Britain. Board of Trade and published by . This book was released on 1909 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Assessment of Older Adults with Diminished Capacity

Download Assessment of Older Adults with Diminished Capacity PDF Online Free

Author :
Publisher : American Bar Association
ISBN 13 :
Total Pages : 152 pages
Book Rating : 4.F/5 ( download)

DOWNLOAD NOW!


Book Synopsis Assessment of Older Adults with Diminished Capacity by :

Download or read book Assessment of Older Adults with Diminished Capacity written by and published by American Bar Association. This book was released on 2008 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Gastro-Archeologist

Download The Gastro-Archeologist PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 3030626210
Total Pages : 312 pages
Book Rating : 4.0/5 (36 download)

DOWNLOAD NOW!


Book Synopsis The Gastro-Archeologist by : Jeremy Woodward

Download or read book The Gastro-Archeologist written by Jeremy Woodward and published by Springer Nature. This book was released on 2021-02-03 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: In order to understand common conditions such as coeliac disease and Crohn’s disease, one must view the gut in its evolutionary context. This is the novel approach to the gut and its diseases that is adopted in this book. The first part tells the story of the evolution of the gut itself – why it came about and how it has influenced the evolution of animals ever since. The second part focuses on the evolution of immunity and how the layers of immune mechanisms are retained in the gut, resembling the strata revealed in an archeological dig. The final part, ‘The Gastro-Archeologist’, ties the first two together and highlights how understanding the gut and immune system in their evolutionary context can help us understand diseases affecting them. Ambitious in its scope but telling a unique story from a refreshingly novel perspective, the book offers an informative and enjoyable read. As the story of the gut, immunity and disease unfolds, the author aims to endow readers with the same sense of awe and excitement that the subject evokes in him. Difficult concepts are illustrated using simple and colourful analogies, and the main content is supplemented with anecdotes and unusual and amusing facts throughout the book. The book is intended for anyone with an interest in the gut, its immunity and diseases, ranging from school and college biology and biomedical students, to professionals working in the field, and to patients suffering from intestinal diseases who want to understand more about their conditions.

Recognition and Management of Pesticide Poisonings (5th Ed. )

Download Recognition and Management of Pesticide Poisonings (5th Ed. ) PDF Online Free

Author :
Publisher : DIANE Publishing
ISBN 13 : 1437914527
Total Pages : 238 pages
Book Rating : 4.4/5 (379 download)

DOWNLOAD NOW!


Book Synopsis Recognition and Management of Pesticide Poisonings (5th Ed. ) by : J. Routt Reigart

Download or read book Recognition and Management of Pesticide Poisonings (5th Ed. ) written by J. Routt Reigart and published by DIANE Publishing. This book was released on 2009-06 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 5th ed. is an update and expansion of the 1989 4th ed. This EPA manual provides health professionals with information on the health hazards of pesticides currently in use, and current consensus recommendations for management of poisonings and injuries caused by them. As with previous updates, this new ed. incorporates new pesticide products that are not necessarily widely known among health professionals. Contents: (1) General Information: Introduction; General Principles in the Management of Acute Pesticide Poisonings; Environmental and Occupational History; (2) Insecticides; (3) Herbicides; (4) Other Pesticides; (5) Index of Signs and Symptoms; Index of Pesticide Products. Charts and tables.

The Education of Physicians for Primary Care

Download The Education of Physicians for Primary Care PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 76 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis The Education of Physicians for Primary Care by : Joel J. Alpert

Download or read book The Education of Physicians for Primary Care written by Joel J. Alpert and published by . This book was released on 1973 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Strengthening the Military Family Readiness System for a Changing American Society

Download Strengthening the Military Family Readiness System for a Changing American Society PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 0309489539
Total Pages : 385 pages
Book Rating : 4.3/5 (94 download)

DOWNLOAD NOW!


Book Synopsis Strengthening the Military Family Readiness System for a Changing American Society by : National Academies of Sciences, Engineering, and Medicine

Download or read book Strengthening the Military Family Readiness System for a Changing American Society written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-10-25 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: The U.S. military has been continuously engaged in foreign conflicts for over two decades. The strains that these deployments, the associated increases in operational tempo, and the general challenges of military life affect not only service members but also the people who depend on them and who support them as they support the nation â€" their families. Family members provide support to service members while they serve or when they have difficulties; family problems can interfere with the ability of service members to deploy or remain in theater; and family members are central influences on whether members continue to serve. In addition, rising family diversity and complexity will likely increase the difficulty of creating military policies, programs and practices that adequately support families in the performance of military duties. Strengthening the Military Family Readiness System for a Changing American Society examines the challenges and opportunities facing military families and what is known about effective strategies for supporting and protecting military children and families, as well as lessons to be learned from these experiences. This report offers recommendations regarding what is needed to strengthen the support system for military families.