Combining NIR Transmission Spectroscopy, Time-resolved Spectroscopy and Diffusion Theory for Analysis of Intact Pharmaceutical Tablets

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ISBN 13 :
Total Pages : 33 pages
Book Rating : 4.:/5 (186 download)

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Book Synopsis Combining NIR Transmission Spectroscopy, Time-resolved Spectroscopy and Diffusion Theory for Analysis of Intact Pharmaceutical Tablets by : Birgitta Strömdahl

Download or read book Combining NIR Transmission Spectroscopy, Time-resolved Spectroscopy and Diffusion Theory for Analysis of Intact Pharmaceutical Tablets written by Birgitta Strömdahl and published by . This book was released on 2004 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Content uniformity of intact pharmaceutical tablets by transmission near-infrared spectroscopy

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ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (14 download)

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Book Synopsis Content uniformity of intact pharmaceutical tablets by transmission near-infrared spectroscopy by : Neville William Broad

Download or read book Content uniformity of intact pharmaceutical tablets by transmission near-infrared spectroscopy written by Neville William Broad and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Content Uniformity of Intact Pharmaceutical Tablets by Transmittance Near-infrared Spectroscopy

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ISBN 13 :
Total Pages : 558 pages
Book Rating : 4.:/5 (926 download)

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Book Synopsis Content Uniformity of Intact Pharmaceutical Tablets by Transmittance Near-infrared Spectroscopy by :

Download or read book Content Uniformity of Intact Pharmaceutical Tablets by Transmittance Near-infrared Spectroscopy written by and published by . This book was released on 2005 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Application of Near-infrared Spectroscopy to the Analysis of Intact Tablets

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ISBN 13 :
Total Pages : 432 pages
Book Rating : 4.:/5 (926 download)

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Book Synopsis The Application of Near-infrared Spectroscopy to the Analysis of Intact Tablets by :

Download or read book The Application of Near-infrared Spectroscopy to the Analysis of Intact Tablets written by and published by . This book was released on 2005 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Near-Infrared Spectroscopy

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Publisher : Springer Nature
ISBN 13 : 9811586489
Total Pages : 593 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Near-Infrared Spectroscopy by : Yukihiro Ozaki

Download or read book Near-Infrared Spectroscopy written by Yukihiro Ozaki and published by Springer Nature. This book was released on 2020-11-13 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides knowledge of the basic theory, spectral analysis methods, chemometrics, instrumentation, and applications of near-infrared (NIR) spectroscopy—not as a handbook but rather as a sourcebook of NIR spectroscopy. Thus, some emphasis is placed on the description of basic knowledge that is important in learning and using NIR spectroscopy. The book also deals with applications for a variety of research fields that are very useful for a wide range of readers from graduate students to scientists and engineers in both academia and industry. For readers who are novices in NIR spectroscopy, this book provides a good introduction, and for those who already are familiar with the field it affords an excellent means of strengthening their knowledge about NIR spectroscopy and keeping abreast of recent developments.

Process Analytical Technology

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Publisher : John Wiley & Sons
ISBN 13 : 140517319X
Total Pages : 472 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Process Analytical Technology by : Katherine A. Bakeev

Download or read book Process Analytical Technology written by Katherine A. Bakeev and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of real or near real time measurement of chemical production process parameters as the basis for achieving control or optimisation of a manufacturing process has wide application in the petrochemical, food and chemical industries. Process analytical chemistry (PAC), or process analytical technology (PAT) as it has recently been called, is now being deployed in the pharmaceutical industry, where it is seen as a technology that can help companies to improve their conformity with manufacturing compliance regulations. The objective of this book is to provide a starting point for implementing process analytical chemistry tools in process monitoring applications or as part of a total quality management system. Written from the perspective of the spectroscopist required to implant PAT tools in a process environment, attention is focussed on measurements that are made "in process" at-line or off-line, providing data on product during manufacture. With chapters covering the key spectroscopic tools, their applications in the pharmaceutical and chemical industries and basic chemometrics, the novice can quickly develop a sound understanding of the most practical technologies and applications. Implementation strategies are fully covered and address some of the critical issues that need to be tackled when setting up a PAT project – including choosing a project with a sound business justification in the first place.

Near-infrared Spectroscopic Assay Transfer for Active Pharmaceutical Ingredients in Intact Tablets

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ISBN 13 :
Total Pages : 626 pages
Book Rating : 4.:/5 (926 download)

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Book Synopsis Near-infrared Spectroscopic Assay Transfer for Active Pharmaceutical Ingredients in Intact Tablets by :

Download or read book Near-infrared Spectroscopic Assay Transfer for Active Pharmaceutical Ingredients in Intact Tablets written by and published by . This book was released on 2005 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pharmaceutical Tablets and Near-infrared Spectral Information

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Publisher :
ISBN 13 :
Total Pages : 253 pages
Book Rating : 4.:/5 (755 download)

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Book Synopsis Pharmaceutical Tablets and Near-infrared Spectral Information by : Muhanned Saeed

Download or read book Pharmaceutical Tablets and Near-infrared Spectral Information written by Muhanned Saeed and published by . This book was released on 2011 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Development of Quantitative Assays for the Actives in Intact Pharmaceutical Capsules Using Near-infrared Spectroscopy

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Publisher :
ISBN 13 :
Total Pages : 630 pages
Book Rating : 4.:/5 (926 download)

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Book Synopsis Development of Quantitative Assays for the Actives in Intact Pharmaceutical Capsules Using Near-infrared Spectroscopy by :

Download or read book Development of Quantitative Assays for the Actives in Intact Pharmaceutical Capsules Using Near-infrared Spectroscopy written by and published by . This book was released on 2007 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Non-destructive Prediction of Drug Release from Tablets Using Near-infrared Spectroscopy

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Publisher :
ISBN 13 :
Total Pages : 212 pages
Book Rating : 4.:/5 (226 download)

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Book Synopsis Non-destructive Prediction of Drug Release from Tablets Using Near-infrared Spectroscopy by : Randall John Voytilla

Download or read book Non-destructive Prediction of Drug Release from Tablets Using Near-infrared Spectroscopy written by Randall John Voytilla and published by . This book was released on 2007 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Development of Quantitiative Assays for the Actives in Intact Pharmaceutical Capsules Using Near-infrared Spectroscopy

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (94 download)

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Book Synopsis Development of Quantitiative Assays for the Actives in Intact Pharmaceutical Capsules Using Near-infrared Spectroscopy by :

Download or read book Development of Quantitiative Assays for the Actives in Intact Pharmaceutical Capsules Using Near-infrared Spectroscopy written by and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chemical Imaging Chemometrics for the Analysis of Pharmaceutical Solid Dosage Forms

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ISBN 13 :
Total Pages : 155 pages
Book Rating : 4.:/5 (758 download)

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Book Synopsis Chemical Imaging Chemometrics for the Analysis of Pharmaceutical Solid Dosage Forms by : Christelle Gendrin

Download or read book Chemical Imaging Chemometrics for the Analysis of Pharmaceutical Solid Dosage Forms written by Christelle Gendrin and published by . This book was released on 2008 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: By combining both spectral and spatial information Near Infrared Chemical Imaging (NIR-CI) allows the identification of the chemical species and their localization. Since the distribution of chemical species influences greatly the quality attributes of the medicine this kind of instrumentation has naturally shown to be very useful for the development of pharmaceutical products. However, each analysis generates thousands of spatially resolved spectra which need to be processed for objective comparison of the data. In the present work, the extraction of distribution maps and their characterization is firstly addressed. In that case the samples' composition is fully known and specific wavelengths or the full reference spectra are used to localize the chemical species. Histogram analysis is performed to assess the homogeneity of the first intermediates revealing a batch with greater inhomogeneity. In the second intermediates, a difference in the particle sizes of two batches is enhanced using a segmentation scheme based on Otsu thresholding and watershed refinement. The usefulness of NIR-CI and image processing to study and compare the quality of intermediates is demonstrated. In a second part, the simultaneous extraction of spectra and distribution maps without a priori information is proven. The accuracy of NMF, BPSS, MCRALS and PMF algorithms are compared. The latter proves to extract both spectral profile and concentration with the best accuracy especially when rotational tools are used to investigate the space of feasible solutions. The last chapter deals with the quantification of API in binary mixtures and pharmaceutical tablets. The quantification without a priori reveals to be quite challenging. With homogeneous sample, the multivariate curve resolution algorithms fail to recover the pure spectra. A segmentation scheme is appropriate only in specific cases if the chemical species particles are larger than the spatial resolution of the device. If a full range of tablets with known concentration is provided, PLS algorithm gives the most accurate quantification results. However, it is demonstrated that with the only knowledge of reference spectra, PLS-DA provides an estimation of the concentration which allows semi-quantitative analysis of samples when the construction of a full range is not possible for instance during the analysis of development samples.

Time Resolved Broadband Spectroscopy from UV to NIR

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (13 download)

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Book Synopsis Time Resolved Broadband Spectroscopy from UV to NIR by : Bastian Baudisch

Download or read book Time Resolved Broadband Spectroscopy from UV to NIR written by Bastian Baudisch and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Near Infrared Spectroscopy and Related Computational Methods

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Publisher : MDPI
ISBN 13 : 303928052X
Total Pages : 496 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Advances in Near Infrared Spectroscopy and Related Computational Methods by : Christian Huck

Download or read book Advances in Near Infrared Spectroscopy and Related Computational Methods written by Christian Huck and published by MDPI. This book was released on 2020-01-03 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last few decades, near-infrared (NIR) spectroscopy has distinguished itself as one of the most rapidly advancing spectroscopic techniques. Mainly known as an analytical tool useful for sample characterization and content quantification, NIR spectroscopy is essential in various other fields, e.g. NIR imaging techniques in biophotonics, medical applications or used for characterization of food products. Its contribution in basic science and physical chemistry should be noted as well, e.g. in exploration of the nature of molecular vibrations or intermolecular interactions. One of the current development trends involves the miniaturization and simplification of instrumentation, creating prospects for the spread of NIR spectrometers at a consumer level in the form of smartphone attachments—a breakthrough not yet accomplished by any other analytical technique. A growing diversity in the related methods and applications has led to a dispersion of these contributions among disparate scientific communities. The aim of this Special Issue was to bring together the communities that may perceive NIR spectroscopy from different perspectives. It resulted in 30 contributions presenting the latest advances in the methodologies essential in near-infrared spectroscopy in a variety of applications.

Use of NIR Spectroscopy and Multivariate Process Spectra Calibration Methodology for Pharmaceutical Solid Samples Analysis

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (112 download)

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Book Synopsis Use of NIR Spectroscopy and Multivariate Process Spectra Calibration Methodology for Pharmaceutical Solid Samples Analysis by : Vanessa Cárdenas Espitia

Download or read book Use of NIR Spectroscopy and Multivariate Process Spectra Calibration Methodology for Pharmaceutical Solid Samples Analysis written by Vanessa Cárdenas Espitia and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Principles of Fluorescence Spectroscopy

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Publisher : Springer Science & Business Media
ISBN 13 : 146157658X
Total Pages : 487 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Principles of Fluorescence Spectroscopy by : Joseph R. Lakowicz

Download or read book Principles of Fluorescence Spectroscopy written by Joseph R. Lakowicz and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluorescence methods are being used increasingly in biochemical, medical, and chemical research. This is because of the inherent sensitivity of this technique. and the favorable time scale of the phenomenon of fluorescence. 8 Fluorescence emission occurs about 10- sec (10 nsec) after light absorp tion. During this period of time a wide range of molecular processes can occur, and these can effect the spectral characteristics of the fluorescent compound. This combination of sensitivity and a favorable time scale allows fluorescence methods to be generally useful for studies of proteins and membranes and their interactions with other macromolecules. This book describes the fundamental aspects of fluorescence. and the biochemical applications of this methodology. Each chapter starts with the -theoreticalbasis of each phenomenon of fluorescence, followed by examples which illustrate the use of the phenomenon in the study of biochemical problems. The book contains numerous figures. It is felt that such graphical presentations contribute to pleasurable reading and increased understand ing. Separate chapters are devoted to fluorescence polarization, lifetimes, quenching, energy transfer, solvent effects, and excited state reactions. To enhance the usefulness of this work as a textbook, problems are included which illustrate the concepts described in each chapter. Furthermore, a separate chapter is devoted to the instrumentation used in fluorescence spectroscopy. This chapter will be especially valuable for those perform ing or contemplating fluorescence measurements. Such measurements are easily compromised by failure to consider a number of simple principles.

Handbook of Stability Testing in Pharmaceutical Development

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Publisher : Springer Science & Business Media
ISBN 13 : 0387856277
Total Pages : 389 pages
Book Rating : 4.3/5 (878 download)

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Book Synopsis Handbook of Stability Testing in Pharmaceutical Development by : Kim Huynh-Ba

Download or read book Handbook of Stability Testing in Pharmaceutical Development written by Kim Huynh-Ba and published by Springer Science & Business Media. This book was released on 2008-11-16 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is the first to cover all aspects of stability testing in pharmaceutical development. Written by a group of international experts, the book presents a scientific understanding of regulations and balances methodologies and best practices.