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Combined Rank Tests For Randomly Censored Paired Data
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Book Synopsis Advances in Survival Analysis by : Narayanaswamy Balakrishnan
Download or read book Advances in Survival Analysis written by Narayanaswamy Balakrishnan and published by Elsevier. This book was released on 2004-01-30 with total page 823 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Statistics: Advances in Survival Analysis covers all important topics in the area of Survival Analysis. Each topic has been covered by one or more chapters written by internationally renowned experts. Each chapter provides a comprehensive and up-to-date review of the topic. Several new illustrative examples have been used to demonstrate the methodologies developed. The book also includes an exhaustive list of important references in the area of Survival Analysis. - Includes up-to-date reviews on many important topics - Chapters written by many internationally renowned experts - Some Chapters provide completely new methodologies and analyses - Includes some new data and methods of analyzing them
Book Synopsis Statistical Models Based on Counting Processes by : Per K. Andersen
Download or read book Statistical Models Based on Counting Processes written by Per K. Andersen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 779 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern survival analysis and more general event history analysis may be effectively handled within the mathematical framework of counting processes. This book presents this theory, which has been the subject of intense research activity over the past 15 years. The exposition of the theory is integrated with careful presentation of many practical examples, drawn almost exclusively from the authors'own experience, with detailed numerical and graphical illustrations. Although Statistical Models Based on Counting Processes may be viewed as a research monograph for mathematical statisticians and biostatisticians, almost all the methods are given in concrete detail for use in practice by other mathematically oriented researchers studying event histories (demographers, econometricians, epidemiologists, actuarial mathematicians, reliability engineers and biologists). Much of the material has so far only been available in the journal literature (if at all), and so a wide variety of researchers will find this an invaluable survey of the subject.
Book Synopsis Design and Analysis of Clinical Trials with Time-to-Event Endpoints by : Karl E. Peace
Download or read book Design and Analysis of Clinical Trials with Time-to-Event Endpoints written by Karl E. Peace and published by CRC Press. This book was released on 2009-04-23 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using time-to-event analysis methodology requires careful definition of the event, censored observation, provision of adequate follow-up, number of events, and independence or "noninformativeness" of the censoring mechanisms relative to the event. Design and Analysis of Clinical Trials with Time-to-Event Endpoints provides a thorough presentation o
Book Synopsis Goodness-of-fit Tests for Survival Models by : Liang Xiu
Download or read book Goodness-of-fit Tests for Survival Models written by Liang Xiu and published by . This book was released on 1993 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Statistical Theory and Method Abstracts by :
Download or read book Statistical Theory and Method Abstracts written by and published by . This book was released on 2001 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Nonparametric Tests for Censored Data by : Vilijandas Bagdonavicius
Download or read book Nonparametric Tests for Censored Data written by Vilijandas Bagdonavicius and published by John Wiley & Sons. This book was released on 2013-02-07 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book concerns testing hypotheses in non-parametric models. Generalizations of many non-parametric tests to the case of censored and truncated data are considered. Most of the test results are proved and real applications are illustrated using examples. Theories and exercises are provided. The incorrect use of many tests applying most statistical software is highlighted and discussed.
Book Synopsis Journal of the American Statistical Association by :
Download or read book Journal of the American Statistical Association written by and published by . This book was released on 2002 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Permutation Tests for Complex Data by : Fortunato Pesarin
Download or read book Permutation Tests for Complex Data written by Fortunato Pesarin and published by John Wiley & Sons. This book was released on 2010-02-25 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complex multivariate testing problems are frequently encountered in many scientific disciplines, such as engineering, medicine and the social sciences. As a result, modern statistics needs permutation testing for complex data with low sample size and many variables, especially in observational studies. The Authors give a general overview on permutation tests with a focus on recent theoretical advances within univariate and multivariate complex permutation testing problems, this book brings the reader completely up to date with today’s current thinking. Key Features: Examines the most up-to-date methodologies of univariate and multivariate permutation testing. Includes extensive software codes in MATLAB, R and SAS, featuring worked examples, and uses real case studies from both experimental and observational studies. Includes a standalone free software NPC Test Release 10 with a graphical interface which allows practitioners from every scientific field to easily implement almost all complex testing procedures included in the book. Presents and discusses solutions to the most important and frequently encountered real problems in multivariate analyses. A supplementary website containing all of the data sets examined in the book along with ready to use software codes. Together with a wide set of application cases, the Authors present a thorough theory of permutation testing both with formal description and proofs, and analysing real case studies. Practitioners and researchers, working in different scientific fields such as engineering, biostatistics, psychology or medicine will benefit from this book.
Book Synopsis Current Index to Statistics, Applications, Methods and Theory by :
Download or read book Current Index to Statistics, Applications, Methods and Theory written by and published by . This book was released on 1992 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Current Index to Statistics (CIS) is a bibliographic index of publications in statistics, probability, and related fields.
Book Synopsis Survival Analysis by : John P. Klein
Download or read book Survival Analysis written by John P. Klein and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Making complex methods more accessible to applied researchers without an advanced mathematical background, the authors present the essence of new techniques available, as well as classical techniques, and apply them to data. Practical suggestions for implementing the various methods are set off in a series of practical notes at the end of each section, while technical details of the derivation of the techniques are sketched in the technical notes. This book will thus be useful for investigators who need to analyse censored or truncated life time data, and as a textbook for a graduate course in survival analysis, the only prerequisite being a standard course in statistical methodology.
Book Synopsis Multivariate Survival Analysis and Competing Risks by : Martin J. Crowder
Download or read book Multivariate Survival Analysis and Competing Risks written by Martin J. Crowder and published by CRC Press. This book was released on 2012-04-17 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multivariate Survival Analysis and Competing Risks introduces univariate survival analysis and extends it to the multivariate case. It covers competing risks and counting processes and provides many real-world examples, exercises, and R code. The text discusses survival data, survival distributions, frailty models, parametric methods, multivariate data and distributions, copulas, continuous failure, parametric likelihood inference, and non- and semi-parametric methods. There are many books covering survival analysis, but very few that cover the multivariate case in any depth. Written for a graduate-level audience in statistics/biostatistics, this book includes practical exercises and R code for the examples. The author is renowned for his clear writing style, and this book continues that trend. It is an excellent reference for graduate students and researchers looking for grounding in this burgeoning field of research.
Download or read book Mathematical Reviews written by and published by . This book was released on 2001 with total page 962 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Statistics for Censored Environmental Data Using Minitab and R by : Dennis R. Helsel
Download or read book Statistics for Censored Environmental Data Using Minitab and R written by Dennis R. Helsel and published by John Wiley & Sons. This book was released on 2012-02-01 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the First Edition " . . . an excellent addition to an upper-level undergraduate course on environmental statistics, and . . . a 'must-have' desk reference for environmental practitioners dealing with censored datasets." —Vadose Zone Journal Statistics for Censored Environmental Data Using Minitab® and R, Second Edition introduces and explains methods for analyzing and interpreting censored data in the environmental sciences. Adapting survival analysis techniques from other fields, the book translates well-established methods from other disciplines into new solutions for environmental studies. This new edition applies methods of survival analysis, including methods for interval-censored data to the interpretation of low-level contaminants in environmental sciences and occupational health. Now incorporating the freely available R software as well as Minitab® into the discussed analyses, the book features newly developed and updated material including: A new chapter on multivariate methods for censored data Use of interval-censored methods for treating true nondetects as lower than and separate from values between the detection and quantitation limits ("remarked data") A section on summing data with nondetects A newly written introduction that discusses invasive data, showing why substitution methods fail Expanded coverage of graphical methods for censored data The author writes in a style that focuses on applications rather than derivations, with chapters organized by key objectives such as computing intervals, comparing groups, and correlation. Examples accompany each procedure, utilizing real-world data that can be analyzed using the Minitab® and R software macros available on the book's related website, and extensive references direct readers to authoritative literature from the environmental sciences. Statistics for Censored Environmental Data Using Minitab® and R, Second Edition is an excellent book for courses on environmental statistics at the upper-undergraduate and graduate levels. The book also serves as a valuable reference for??environmental professionals, biologists, and ecologists who focus on the water sciences, air quality, and soil science.
Download or read book Permutation Tests written by Phillip Good and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: A step-by-step guide to the application of permutation tests in biology, medicine, science, and engineering. The intuitive and informal style makes this manual ideally suitable for students and researchers approaching these methods for the first time. In particular, it shows how to handle the problems of missing and censored data, nonresponders, after-the-fact covariates, and outliers.
Book Synopsis Cluster Randomization Trials by : Sin-Ho Jung
Download or read book Cluster Randomization Trials written by Sin-Ho Jung and published by CRC Press. This book was released on 2024-12-20 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oftentimes, small groups (called clusters) of individuals (called subunits) are randomized between treatment arms. Typically, clusters are families, classes, communities, surgeons operating patients, and so on. Such trials are called cluster randomization trials (CRTs). The subunits in each cluster share common frailties so that their outcomes tend to be positively correlated. Since clusters are independent, the data in two arms are independent in CRTs. In a clinical trial, multiple sites (such as teeth or ears) from each subject may be randomized between different treatment arms. In this case, the sites (subunits) of each subject (cluster) share common genetic, physiological, or environmental characteristics so that their observations tend to be positively correlated. This kind of trials are called subunit randomization trials (SRTs). In SRTs, dependency exists both within and between treatment arms. Individually randomized group treatment (IRGT) trials are composite of traditional independent subject randomization and CRTs. In an IRGT trial, the control arm is to treat patients individually, whereas the experimental arm is to treat patients using a group training, education, or treatment to increase the treatment effect by close interactions among patients. As a result, the outcome data of the control arm are independent as in traditional trials, but those in the experimental arm are correlated within each group (cluster) as in CRTs. Hence, two arms in IRGT trials have different dependency structures. Unlike standard CRTs, clusters of IRGT trials are usually organized after randomization. But statistically, they have identical statistical issues between the two types of trials, i.e., accounting for the dependency within each cluster. Although this book is entitled Cluster Randomization Trials, it covers all three types of trials (i.e., CRTs, SRTs, and IRGT trials) resulting in clustered data. For outcome variables of binary, continuous, and time-to-event types, we investigate generalized estimating equation type statistical tests and their sample size formulas. Also presented are random number generation algorithms for different types of outcome variables and randomization methods. The methods are discussed in terms of clinical trials, but can be used to design and analyze any types of experiments involving clustered data. This book also discusses statistical methods for various types of biomarker studies, including ROC methods, with clustered data. Key Features: Includes extensive statistical tests and their sample size formulas for various types of clinical trials resulting in clustered data. Handles different variable types of endpoints separately. Discusses algorithms to generate clustered binary and survival data that are useful for simulations. Covers statistical tests and sample size formulas for medical tests with clustered data.
Book Synopsis Innovative Statistics in Regulatory Science by : Shein-Chung Chow
Download or read book Innovative Statistics in Regulatory Science written by Shein-Chung Chow and published by CRC Press. This book was released on 2019-11-14 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical methods that are commonly used in the review and approval process of regulatory submissions are usually referred to as statistics in regulatory science or regulatory statistics. In a broader sense, statistics in regulatory science can be defined as valid statistics that are employed in the review and approval process of regulatory submissions of pharmaceutical products. In addition, statistics in regulatory science are involved with the development of regulatory policy, guidance, and regulatory critical clinical initiatives related research. This book is devoted to the discussion of statistics in regulatory science for pharmaceutical development. It covers practical issues that are commonly encountered in regulatory science of pharmaceutical research and development including topics related to research activities, review of regulatory submissions, recent critical clinical initiatives, and policy/guidance development in regulatory science. Devoted entirely to discussing statistics in regulatory science for pharmaceutical development. Reviews critical issues (e.g., endpoint/margin selection and complex innovative design such as adaptive trial design) in the pharmaceutical development and regulatory approval process. Clarifies controversial statistical issues (e.g., hypothesis testing versus confidence interval approach, missing data/estimands, multiplicity, and Bayesian design and approach) in review/approval of regulatory submissions. Proposes innovative thinking regarding study designs and statistical methods (e.g., n-of-1 trial design, adaptive trial design, and probability monitoring procedure for sample size) for rare disease drug development. Provides insight regarding current regulatory clinical initiatives (e.g., precision/personalized medicine, biomarker-driven target clinical trials, model informed drug development, big data analytics, and real world data/evidence). This book provides key statistical concepts, innovative designs, and analysis methods that are useful in regulatory science. Also included are some practical, challenging, and controversial issues that are commonly seen in the review and approval process of regulatory submissions. About the author Shein-Chung Chow, Ph.D. is currently a Professor at Duke University School of Medicine, Durham, NC. He was previously the Associate Director at the Office of Biostatistics, Center for Drug Evaluation and Research, United States Food and Drug Administration (FDA). Dr. Chow has also held various positions in the pharmaceutical industry such as Vice President at Millennium, Cambridge, MA, Executive Director at Covance, Princeton, NJ, and Director and Department Head at Bristol-Myers Squibb, Plainsboro, NJ. He was elected Fellow of the American Statistical Association and an elected member of the ISI (International Statistical Institute). Dr. Chow is Editor-in-Chief of the Journal of Biopharmaceutical Statistics and Biostatistics Book Series, Chapman and Hall/CRC Press, Taylor & Francis, New York. Dr. Chow is the author or co-author of over 300 methodology papers and 30 books.
Book Synopsis Haschek and Rousseaux's Handbook of Toxicologic Pathology by : Wanda M Haschek
Download or read book Haschek and Rousseaux's Handbook of Toxicologic Pathology written by Wanda M Haschek and published by Academic Press. This book was released on 2013-05-01 with total page 3055 pages. Available in PDF, EPUB and Kindle. Book excerpt: Haschek and Rousseaux's Handbook of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. The 3e has been expanded by a full volume, and covers aspects of safety assessment not discussed in the 2e. Completely revised with many new chapters, it remains the most authoritative reference on toxicologic pathology for scientists and researchers studying and making decisions on drugs, biologics, medical devices and other chemicals, including agrochemicals and environmental contaminants. New topics include safety assessment, the drug life cycle, risk assessment, communication and management, carcinogenicity assessment, pharmacology and pharmacokinetics, biomarkers in toxicologic pathology, quality assurance, peer review, agrochemicals, nanotechnology, food and toxicologic pathology, the environment and toxicologic pathology and more. - Provides new chapters and in-depth discussion of timely topics in the area of toxicologic pathology and broadens the scope of the audience to include toxicologists and pathologists working in a variety of settings - Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology - Features hundreds of full color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations
