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Combination Therapy Against Multidrug Resistance
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Book Synopsis Combination Therapy Against Multidrug Resistance by : Mohmmad Younus Wani
Download or read book Combination Therapy Against Multidrug Resistance written by Mohmmad Younus Wani and published by Academic Press. This book was released on 2020-04-30 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combination Therapy against Multidrug Resistance explores the potential of combination therapy as an efficient strategy to combat multi-drug resistance. Multidrug resistance (MDR) occurs when microorganisms such as bacteria, fungi, viruses, and parasites are excessively exposed to antimicrobial drugs such as antibiotics, antifungals, or antivirals, and in response the microorganism undergoes mutations or develops different resistance mechanisms to combat the drug for its survival. MDR is becoming an increasingly serious problem in both developed and developing nations. Bacterial resistance to antibiotics has developed faster than the production of new antibiotics, making bacterial infections increasingly difficult to treat, and the same is true for a variety of other diseases. Combination therapy proves to be a promising strategy as it offers potential benefits such as a broad spectrum of efficacy, greater potency than the drugs used in monotherapy, improved safety and tolerability, and reduction in the number of resistant organisms. This book considers how combination therapy can be applied in multiple situations, including cancer, HIV, tuberculosis, fungal infections, and more. Combination Therapy Against Multidrug Resistance gathers the most relevant information on the prospects of combination therapy as a strategy to combat multridrug resistance and helping to motivate the industrial sector and government agencies to invest more in research and development of this strategy as a weapon to tackle the multidrug resistance problem. It will be useful to academics and researchers involved in the development of new antimicrobial or antiinfective agents and treatment strtategies to combat multidrug resistance. Clinicians and medical nurses working in the field of infection prevention and control (IPC) will also find the book relevant - Explores strategic methods with investigation of both short- and long-term goals to combat multidrug resistance - Presents a broad scope to understand fully the ways to apply combined therapy to multidrug resistance - Provides an overview of combination therapy, but also includes specific cases such as cancer, tuberculosis, HIV and malaria
Book Synopsis Combination Therapy Against Multidrug Resistance by : Mohmmad Younus Wani
Download or read book Combination Therapy Against Multidrug Resistance written by Mohmmad Younus Wani and published by Academic Press. This book was released on 2020-06 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combination Therapy Against Multidrug Resistance explores the potential of combination therapy as an efficient strategy to combat multi-drug resistance. The book considers how combination therapy can apply in multiple situations, including cancer, HIV, tuberculosis, fungal infections, and more. Sections cover the most relevant information on prospects of combination therapy as a strategy to combat multidrug resistance and help motivate the industrial sector and government agencies to invest more in research and development. This comprehensive resource is useful to academics and researchers involved in the development of new antimicrobial or anti-infective agents and treatment strategies to combat multidrug resistance. Explores strategic methods with investigation of both short- and long-term goals to combat multidrug resistance Presents a broad scope to help users fully understand how to apply combined therapy to multidrug resistance Provides an overview of combination therapy, but also includes specific cases such as cancer, tuberculosis, HIV and malaria
Book Synopsis Microbial Threats to Health by : Institute of Medicine
Download or read book Microbial Threats to Health written by Institute of Medicine and published by National Academies Press. This book was released on 2003-08-25 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are a global hazard that puts every nation and every person at risk. The recent SARS outbreak is a prime example. Knowing neither geographic nor political borders, often arriving silently and lethally, microbial pathogens constitute a grave threat to the health of humans. Indeed, a majority of countries recently identified the spread of infectious disease as the greatest global problem they confront. Throughout history, humans have struggled to control both the causes and consequences of infectious diseases and we will continue to do so into the foreseeable future. Following up on a high-profile 1992 report from the Institute of Medicine, Microbial Threats to Health examines the current state of knowledge and policy pertaining to emerging and re-emerging infectious diseases from around the globe. It examines the spectrum of microbial threats, factors in disease emergence, and the ultimate capacity of the United States to meet the challenges posed by microbial threats to human health. From the impact of war or technology on disease emergence to the development of enhanced disease surveillance and vaccine strategies, Microbial Threats to Health contains valuable information for researchers, students, health care providers, policymakers, public health officials. and the interested public.
Book Synopsis Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components by : Mahendra Rai
Download or read book Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components written by Mahendra Rai and published by Academic Press. This book was released on 2013-05-24 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and their Components offers scientists a single source aimed at fighting specific multidrug-resistant (MDR) microorganisms such as bacteria, protozoans, viruses and fungi using natural products. This essential reference discusses herbal extracts and essential oils used or under investigation to treat MDR infections, as well as those containing antimicrobial activity that could be of potential interest in future studies against MDR microorganisms. The need to combat multidrug-resistant microorganisms is an urgent one and this book provides important coverage of mechanism of action, the advantages and disadvantages of using herbal extracts, essential oils and their components and more to aid researchers in effective antimicrobial drug discovery - Addresses the need to develop safe and effective approaches to coping with resistance to all classes of antimicrobial drugs - Provides readers with current evidence-based content aimed at using herbal extracts and essential oils in antimicrobial drug development - Includes chapters devoted to the activity of herbal products against herpes, AIDS, tuberculosis, drug-resistant cancer cells and more
Book Synopsis Mechanisms of antibiotic resistance by : Jun Lin
Download or read book Mechanisms of antibiotic resistance written by Jun Lin and published by Frontiers Media SA. This book was released on 2015-06-01 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.
Book Synopsis Antibiotics in Laboratory Medicine by : Daniel Amsterdam
Download or read book Antibiotics in Laboratory Medicine written by Daniel Amsterdam and published by Lippincott Williams & Wilkins. This book was released on 2014-08-08 with total page 1196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotics in Laboratory Medicine has been a mainstay resource for practitioners/providers, investigators, and pharmaceutical researchers of new anti-infective compounds for the past 30 years. This edition includes new chapters on the predictive value of in vitro laboratory testing and the improvement of patient care in the hospital environment through antimicrobial stewardship.
Book Synopsis Severe Community Acquired Pneumonia by : Jordi Rello
Download or read book Severe Community Acquired Pneumonia written by Jordi Rello and published by Springer Science & Business Media. This book was released on 2001-06-30 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Severe Community Acquired Pneumonia is a book in which chapters are authored and the same topics discussed by North American and European experts. This approach provides a unique opportunity to view the different perspectives and points of view on this subject. Severe CAP is a common clinical problem encountered in the ICU setting. This book reviews topics concerning the pathogenesis, diagnosis and management of SCAP. The discussions on the role of alcohol in severe CAP and adjunctive therapies are important topics that further our understanding of this severe respiratory infection.
Book Synopsis Vascular Medicine: A Companion to Braunwald's Heart Disease E-Book by : Mark Creager
Download or read book Vascular Medicine: A Companion to Braunwald's Heart Disease E-Book written by Mark Creager and published by Elsevier Health Sciences. This book was released on 2019-05-22 with total page 963 pages. Available in PDF, EPUB and Kindle. Book excerpt: With authoritative coverage of everything from recent discoveries in the field of vascular biology to recent clinical trials and evidence-based treatment strategies, Vascular Medicine, 3rd Edition, is your go-to resource for improving your patients' cardiovascular health. Part of the Braunwald family of renowned cardiology references, this updated volume integrates a contemporary understanding of vascular biology with a thorough review of clinical vascular diseases, making it an ideal reference for vascular medicine specialists, general cardiologists, interventional cardiologists, vascular surgeons, and interventional radiologists. - Incorporates technologic advances in vascular imaging – including ultrasound, MRI, CTA, and catheter-based angiography – along with more than 230 new figures, providing an up-to-date and complete view of the vascular system and vascular diseases. - Covers novel antithrombotic therapies for peripheral artery disease and venous thromboemboism, advances in endovascular interventions for aortic aneurysms, and today's best surgical treatments for vascular diseases. - Includes seven new chapters: Pathobiology of Aortic Aneurysms; Pathobiology and Assessment of Cardiovascular Fibrosis; Large Vessel Vasculitis; Medium and Small Vessel Vasculitis; Epidemiology and Prognosis of Venous Thromboembolic Disease; Fibromuscular Dysplasia; and Dermatologic Manifestations of Vascular Disease. - Discusses methods for aggressive patient management and disease prevention to ensure minimal risk of further cardiovascular problems. - Keeps you current with ACC/AHA and ECC guidelines and the best ways to implement them in clinical practice. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices
Book Synopsis Antimicrobial Resistance by : World Health Organization
Download or read book Antimicrobial Resistance written by World Health Organization and published by . This book was released on 2014 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summary report published as technical document with reference number: WHO/HSE/PED/AIP/2014.2.
Book Synopsis Comprehensive Hypertension E-Book by : Gregory Y. H. Lip
Download or read book Comprehensive Hypertension E-Book written by Gregory Y. H. Lip and published by Elsevier Health Sciences. This book was released on 2007-06-28 with total page 1247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is today's most in-depth reference for any cardiologist, internist, or nephrologist interested in hypertension. Drawing from international experience in cardiology, physiology, and nephrology, Drs. Lip and Hall have assembled a group of section editors and contributors second to none. You'll find the long-term effects of primary and secondary hypertension and a lengthy section on hypertensions for special populations featured prominently. Prevention and treatment of hypertension are covered in detail, from lifestyle and diet issues to drug choice and delivery, and the section on comparison of guidelines is unique to this book. Find comprehensive coverage of hypertension including pathogenesis, prevention, and treatment all in one practical volume. See the complete systemic problems of hypertension at a glance with detailed, full-color illustrations of cellular and clinical manifestations. Simplify navigating the complexities of hypertension using algorithms for clinical exam and diagnosis. Get specific insight into prevention and treatment of hypertension in special populations. Go global with a comprehensive section on worldwide guidelines and the application of clinical material to local standards of practice.
Book Synopsis Multi-Drug Resistance in Cancer by : Jun Zhou
Download or read book Multi-Drug Resistance in Cancer written by Jun Zhou and published by Humana Press. This book was released on 2012-08-09 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemotherapy is one of the major treatment options for cancer patients; however, the efficacy of chemotherapeutic management of cancer is severely limited by multidrug resistance, in that cancer cells become simultaneously resistant to many structurally and mechanistically unrelated drugs. In the past three decades, a number of mechanisms by which cancer cells acquire multidrug resistance have been discovered. In addition, the development of agents or strategies to overcome resistance has been the subject of intense study. This book contains comprehensive and up-to-date reviews of multidrug resistance mechanisms, from over-expression of ATP-binding cassette drug transporters such as P-glycoprotein, multidrug resistance-associated proteins, and breast cancer resistance p- tein to the drug ratio-dependent antagonism and the paradigm of cancer stem cells. The book also includes strategies to overcome multidrug resistance, from the development of compounds that inhibit drug transporter function to the modulation of transporter expression. In addition, this book contains techniques for the detection and imaging of drug transporters, methods for the investigation of drug resistance in animal models, and strategies to evaluate the efficacy of resistance reversal agents. The book intends to provide a state-of-the-art collection of reviews and methods for both basic and clinician investigators who are interested in cancer multidrug resistance mechanisms and reversal strategies. Tianjin, China Jun Zhou v Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix 1 Multidrug Resistance in Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Bruce C. Baguley 2 Multidrug Resistance in Oncology and Beyond: From Imaging of Drug Efflux Pumps to Cellular Drug Targets . . . . . . . . . . . . . . . . . . . . . . . . . .
Book Synopsis Elsevier's 2022 Intravenous Medications - E-Book by : Shelly Rainforth Collins
Download or read book Elsevier's 2022 Intravenous Medications - E-Book written by Shelly Rainforth Collins and published by Elsevier Health Sciences. This book was released on 2021-04-16 with total page 1408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Find the essential information you need to safely administer more than 400 intravenous drugs! For more than 45 years, Gahart’s Intravenous Medications: A Handbook for Nurses and Health Professionals has been a trusted resource for comprehensive drug coverage, unparalleled accuracy, and an intuitive quick-access format. In addition to updated drug interactions, precautions, alerts, and patient teaching instructions for all existing IV drugs, the 2022 edition includes approximately 10 new monographs of the most recent IV drugs to be approved by the FDA. Administering intravenous drugs is a critical task — inaccurate or out-of-date information is not an option. Known as the #1 IV drug handbook on the market, and with its history of impeccable accuracy, Gahart’s annual publication gives you the extra confidence and guidance you need to safely and effectively treat patients. Monographs on more than 400 IV drugs offer an impressive breadth of coverage that goes well beyond any comparable drug reference. Updated annual publication prevents you from referencing outdated information. Additional drug monographs are provided on the companion Evolve website. 45-year history of impeccable accuracy reinforces the importance of safe IV drug administration. Perfect depth of information equips you with everything that is needed for safe administration of IV drugs — nothing more, nothing less. Proven, clinically optimized format keeps all dosage information for each drug on either a single page or a two-page spread to prevent hand contamination by having to turn a page. Highlighted Black Box Warnings and relevant content make locating critical information fast and easy. Special circumstances in blue-screened text call attention to important circumstances that may not warrant Black Box Warnings. Life-stage dosage variances are highlighted for geriatric, pediatric, infant, and neonatal patients. Dilution and dosage charts within monographs provide quick access to essential clinical information. Convenient, alphabetical format organizes all drug monographs by generic name, allowing you to find any drug in seconds. NEW! Drug monographs for newly approved drugs by the FDA provide you with the most current drug information. Updates on drug interactions, precautions, alerts, and more have been made throughout the guide to reflect all changes to existing medications.
Book Synopsis Economic Analysis of Malaria Control in Sub-Saharan Africa by : Catherine Cavallaro Goodman
Download or read book Economic Analysis of Malaria Control in Sub-Saharan Africa written by Catherine Cavallaro Goodman and published by . This book was released on 2000 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Polymyxin Antibiotics by : Jian Li (Pharmacologist)
Download or read book Polymyxin Antibiotics written by Jian Li (Pharmacologist) and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: It is our wish that readers discover the importance of polymyxin structure in relation to the mechanisms of activity, resistance and toxicity. We emphasized that reliable analytic methods for polymyxins are critical when investigating their pharmacokinetics (PK) and pharmacodynamics (PD). The complicated dose definitions and different pharmacopoeial standards have already compromised the safe use of polymyxins in patients. Therefore, informed by the latest pharmacological information, scientifically-based dosing recommendations have been proposed for intravenous polymyxins. Considering the PK/PD limitations and potential development of resistance, polymyxin combinations are encouraged; however, the current literature has not shown definite microbiological benefits, possibly because most clinical studies to date overlooked key PK/PD principles. Nephrotoxicity is the major dose-limiting factor and it is imperative to elucidate the mechanisms and develop novel approaches to minimize polymyxin-associated toxicities. In addition, the anti-endotoxin effect of polymyxins supports their clinical use to treat Gram-negative sepsis. Fortunately, the discovery of new-generation polymyxins with wider therapeutic windows has benefited from the latest achievements in polymyxin research.
Book Synopsis Resistance of Pseudomonas Aeruginosa by : Michael Robert Withington Brown
Download or read book Resistance of Pseudomonas Aeruginosa written by Michael Robert Withington Brown and published by John Wiley & Sons. This book was released on 1975 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Dynamic Multidrug Therapies for HIV by : Lawrence M Wein
Download or read book Dynamic Multidrug Therapies for HIV written by Lawrence M Wein and published by Legare Street Press. This book was released on 2022-10-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Book Synopsis Guidelines for the Programmatic Management of Drug-Resistant Tuberculosis by : World Health Organization
Download or read book Guidelines for the Programmatic Management of Drug-Resistant Tuberculosis written by World Health Organization and published by . This book was released on 2015-04-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 2011 update of Guidelines for the programmatic management of drug-resistant tuberculosis is intended as a tool for use by public health professionals working in response to the Sixty-second World Health Assembly's resolution on prevention and control of multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis. Resolution WHA62.15, adopted in 2009, calls on Member States to develop a comprehensive framework for the management and care of patients with drug-resistant TB. The recommendations contained in these guidelines address the most topical questions concerning the programmatic management of drug-resistant TB: case-finding, multidrug resistance, treatment regimens, monitoring the response to treatment, and selecting models of care. The guidelines primarily target staff and medical practitioners working in TB treatment and control, and partners and organizations providing technical and financial support for care of drug-resistant TB in settings where resources are limited.
