Planning Clinical Research

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Publisher : Cambridge University Press
ISBN 13 : 0521840635
Total Pages : 445 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis Planning Clinical Research by : Robert A. Parker

Download or read book Planning Clinical Research written by Robert A. Parker and published by Cambridge University Press. This book was released on 2016-10-12 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: Planning clinical research requires many decisions. The authors of this book explain key decisions with examples showing what works and what does not.

Practical Psychiatric Epidemiology

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Publisher : Oxford University Press
ISBN 13 : 0191054461
Total Pages : 508 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis Practical Psychiatric Epidemiology by : Jayati Das-Munshi

Download or read book Practical Psychiatric Epidemiology written by Jayati Das-Munshi and published by Oxford University Press. This book was released on 2020-04-30 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epidemiology has been defined as the study of the distribution and determinants of health states or events in defined populations and its application to the control of health problems. Psychiatric epidemiology has continued to develop and apply these core principles in relation to mental health and mental disorders. This long-awaited second edition of Practical Psychiatric Epidemiology covers all of the considerable new developments in psychiatric epidemiology that have occurred since the first edition was published. It includes new content on key topics such as life course epidemiology, gene/environment interactions, bioethics, patient and public involvement in research, mixed methods research, new statistical methods, case registers, policy, and implementation. Looking to the future of this rapidly evolving scientific discipline and how it will to respond to the emerging opportunities and challenges posed by 'big data', new technologies, open science and globalisation, this new edition will continue to serve as an invaluable reference for clinicians in practice and in training. It will also be of interest to researchers in mental health and people studying or teaching psychiatric epidemiology at undergraduate or postgraduate level.

Cohort Studies in Health Sciences

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Publisher : Intechopen
ISBN 13 : 1789236940
Total Pages : 73 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Cohort Studies in Health Sciences by : R. Mauricio Barría

Download or read book Cohort Studies in Health Sciences written by R. Mauricio Barría and published by Intechopen. This book was released on 2018 with total page 73 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introductory Chapter: The Contribution of Cohort Studies to Health Sciences.

Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide

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Publisher : Government Printing Office
ISBN 13 : 1587634236
Total Pages : 236 pages
Book Rating : 4.5/5 (876 download)

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Book Synopsis Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide by : Agency for Health Care Research and Quality (U.S.)

Download or read book Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide written by Agency for Health Care Research and Quality (U.S.) and published by Government Printing Office. This book was released on 2013-02-21 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)

Age-Period-Cohort Analysis

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Publisher : CRC Press
ISBN 13 : 1466507535
Total Pages : 352 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Age-Period-Cohort Analysis by : Yang Yang

Download or read book Age-Period-Cohort Analysis written by Yang Yang and published by CRC Press. This book was released on 2016-04-19 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the ways in which statistical models, methods, and research designs can be used to open new possibilities for APC analysis. Within a single, consistent HAPC-GLMM statistical modeling framework, the authors synthesize APC models and methods for three research designs: age-by-time period tables of population rates or proportions, repeated cross-section sample surveys, and accelerated longitudinal panel studies. They show how the empirical application of the models to various problems leads to many fascinating findings on how outcome variables develop along the age, period, and cohort dimensions.

Cohort Analysis in Social Research

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Publisher : Springer Science & Business Media
ISBN 13 : 1461385369
Total Pages : 402 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Cohort Analysis in Social Research by : W.M. Mason

Download or read book Cohort Analysis in Social Research written by W.M. Mason and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: The existence of the present volume can be traced to methodological concerns about cohort analysis, all of which were evident throughout most of the social sciences by the late 1970s. For some social scientists, they became part of a broader discussion concerning the need for new analytical techniques for research based on longitudinal data. In 1976, the Social Science Research Council (SSRC), with funds from the National Institute of Education, established a Committee on the Methodology of Longitudinal Research. (The scholars who comprised this committee are listed at the front of this volume. ) As part of the efforts of this Committee, an interdisciplinary conference on cohort analysis was held in the summer of 1979, in Snowmass, Colorado. Much of the work presented here stems from that conference, the purpose of which was to promote the development of general methodological tools for the study of social change. The conference included five major presentations by (1) William Mason and Herbert Smith, (2) Karl J6reskog and Dag S6rbom, (3) Gregory Markus, (4) John Hobcraft, Jane Menken and Samuel Preston, and (5) Stephen Fienberg and William Mason. The formal presentations were each followed by extensive discussion, which involved as participants: Paul Baltes, William Butz, Philip Converse, Otis Dudley Duncan, David Freedman, William Meredith, John Nesselroade, Daniel Price, Thomas Pullum, Peter Read, Matilda White Riley, Norman Ryder, Warren Sanderson, Warner Schaie, Burton Singer, Nancy Tuma, Harrison White, and Halliman Winsborough.

A Unified Model of Cohort Mortality for Economic Analysis

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Publisher : International Monetary Fund
ISBN 13 : 151356949X
Total Pages : 67 pages
Book Rating : 4.5/5 (135 download)

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Book Synopsis A Unified Model of Cohort Mortality for Economic Analysis by : Adriana Lleras-Muney

Download or read book A Unified Model of Cohort Mortality for Economic Analysis written by Adriana Lleras-Muney and published by International Monetary Fund. This book was released on 2021-02-12 with total page 67 pages. Available in PDF, EPUB and Kindle. Book excerpt: We propose a dynamic production function of population health and mortality from birth onwards. Our parsimonious model provides an excellent fit for the mortality and survival curves for both primate and human populations since 1816. The model sheds light on the dynamics behind many phenomena documented in the literature, including (i) the existence and evolution of mortality gradients across socio-economic statuses, (ii) non-monotonic dynamic effects of in-utero shocks, (iii) persistent or “scarring” effects of wars and (iv) mortality displacement after large temporary shocks such as extreme weather.

Critical Appraisal of Epidemiological Studies and Clinical Trials

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Publisher : OUP Oxford
ISBN 13 : 0191004944
Total Pages : 615 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis Critical Appraisal of Epidemiological Studies and Clinical Trials by : Mark Elwood

Download or read book Critical Appraisal of Epidemiological Studies and Clinical Trials written by Mark Elwood and published by OUP Oxford. This book was released on 2007-02-22 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a logical system of critical appraisal, to allow readers to evaluate studies and to carry out their own studies more effectively. This system emphasizes the central importance of cause and effect relationships. Its great strength is that it is applicable to a wide range of issues, and both to intervention trials and observational studies. This system unifies the often different approaches used in epidemiology, health services research, clinical trials, and evidence-based medicine, starting from a logical consideration of cause and effect. The author's approach to the issues of study design, selection of subjects, bias, confounding, and the place of statistical methods has been praised for its clarity and interest. Systematic reviews, meta-analysis, and the applications of this logic to evidence-based medicine, knowledge-based health care, and health practice and policy are discussed. Current and often controversial examples are used, including screening for prostate cancer, publication bias in psychiatry, public health issues in developing countries, and conflicts between observational studies and randomized trials. Statistical issues are explained clearly without complex mathematics, and the most useful methods are summarized in the appendix. The final chapters give six applications of the critical appraisal of major studies: randomized trials of medical treatment and prevention, a prospective and a retrospective cohort study, a small matched case-control study, and a large case-control study. In these chapters, sections of the original papers are reproduced and the original studies placed in context by a summary of current developments.

Epidemiology and Biostatistics

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Publisher : Springer
ISBN 13 : 3319974335
Total Pages : 99 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Epidemiology and Biostatistics by : Bryan Kestenbaum

Download or read book Epidemiology and Biostatistics written by Bryan Kestenbaum and published by Springer. This book was released on 2018-10-12 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: This workbook is designed to teach the major fundamental concepts in Epidemiology, Biostatistics, and clinical research design alongside the textbook "Epidemiology and Biostatistics, 2nd Edition". It is written in concise and organized fashion with many examples to illustrate the concepts deriving from a collection of written materials created to teach Epidemiology and Biostatistics to medical students. The major differences from related titles include a “story” based approach toward teaching the material, relative brevity while maintaining focus on key concepts, and taking the perspective of first-time learners (avoiding and/or clearly defining jargon, using clear common-sense language). It features a variety of questions: long, short, and multiple choice questions. The workbook is made to provide students with the tools necessary to form their own informed conclusions from the clinical research literature.

Public Health Research Methods

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Publisher : SAGE
ISBN 13 : 1452241333
Total Pages : 833 pages
Book Rating : 4.4/5 (522 download)

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Book Synopsis Public Health Research Methods by : Greg Guest

Download or read book Public Health Research Methods written by Greg Guest and published by SAGE. This book was released on 2015 with total page 833 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a comprehensive foundation for planning, executing, and monitoring public health research of all types, this book goes beyond traditional epidemiologic research designs to cover technology-based approaches emerging in the new public health landscape.

Cohort Analysis

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Publisher : SAGE
ISBN 13 : 9780761922155
Total Pages : 76 pages
Book Rating : 4.9/5 (221 download)

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Book Synopsis Cohort Analysis by : Norval D. Glenn

Download or read book Cohort Analysis written by Norval D. Glenn and published by SAGE. This book was released on 2005-01-10 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: A method for studying changes in group patterns -- particularly groups based on age -- cohort analysis seeks to isolate changes attributable to alterations in behaviour or attitudes within an age group; as an example of behaviour change, the pattern of consumption of alcohol within a cohort is analyzed.

The Life Project

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Publisher : Penguin UK
ISBN 13 : 0141976624
Total Pages : 376 pages
Book Rating : 4.1/5 (419 download)

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Book Synopsis The Life Project by : Helen Pearson

Download or read book The Life Project written by Helen Pearson and published by Penguin UK. This book was released on 2016-02-25 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: LONGLISTED FOR THE 2017 ORWELL PRIZE The remarkable story of a unique series of studies that have touched the lives of almost everyone in Britain today On 3rd March 1946 a survey began that is, today, the longest-running study of human development in the world, growing to encompass six generations of children, 150,000 individuals and some of the best-studied people on the planet. The simple act of observing human life has changed the way we are born, schooled, parent and die, irrevocably altering our understanding of inequality and health. This is the tale of these studies; the scientists who created and sustain them, the remarkable discoveries that have come from them. The envy of scientists around the world, they are one of Britain's best-kept secrets.

Drug Epidemiology and Post-Marketing Surveillance

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Publisher : Springer Science & Business Media
ISBN 13 : 1489925872
Total Pages : 171 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Drug Epidemiology and Post-Marketing Surveillance by : Brian L. Strom

Download or read book Drug Epidemiology and Post-Marketing Surveillance written by Brian L. Strom and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a summary of material presented in the course given in the International School of Phannacology on "Drug Epidemiology and Post-Marketing Surveillance" between September 27 and October 8, 1990, at the "Ettore Majorana Center for Scientific Culture" in Erice, Sicily. The course, which was a NATO Advanced Study Institute, included lectures and workshops presented by experts in the new field of phannacoepidemiology. The material covered includes various approaches to spontaneous reporting of adverse drug reactions, including aggregate approaches, such as those used in France, and detailed analyses of individual reports, such as that done in The Netherlands and in Sweden. Also, included are studies using traditional epidemiology methods. In addition, modern pharmacoepidemiology makes considerable use of automated databases. As such, information is presented on their use as well. Phannacoepidemiology started in hospitals and some of the newest work in the field is returning to the hospital as a site for studies. Material on these topics was presented as well. Finally, selected new methodologic developments were outlined in specific examples presented that were of regulatory and commercial importance. This new field of phannacoepidemiology is exploding in interest internationally. Evidence of this is the increasing development of pharmacoepidemiology programs in industry, medical schools, pharmacy schools, and schools of public health. Also, there is a new International Society ofPhannacoepidemiology. Practitioners in this field tend to specialize in either analyses of spontaneous reporting or the use of formal epidemiologic techniques.

Registries for Evaluating Patient Outcomes

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Publisher : Government Printing Office
ISBN 13 : 1587634333
Total Pages : 385 pages
Book Rating : 4.5/5 (876 download)

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Book Synopsis Registries for Evaluating Patient Outcomes by : Agency for Healthcare Research and Quality/AHRQ

Download or read book Registries for Evaluating Patient Outcomes written by Agency for Healthcare Research and Quality/AHRQ and published by Government Printing Office. This book was released on 2014-04-01 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.

Analysis of Cancer Risks in Populations Near Nuclear Facilities

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Author :
Publisher : National Academies Press
ISBN 13 : 0309255716
Total Pages : 424 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Analysis of Cancer Risks in Populations Near Nuclear Facilities by : National Research Council

Download or read book Analysis of Cancer Risks in Populations Near Nuclear Facilities written by National Research Council and published by National Academies Press. This book was released on 2012-06-29 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the late 1980s, the National Cancer Institute initiated an investigation of cancer risks in populations near 52 commercial nuclear power plants and 10 Department of Energy nuclear facilities (including research and nuclear weapons production facilities and one reprocessing plant) in the United States. The results of the NCI investigation were used a primary resource for communicating with the public about the cancer risks near the nuclear facilities. However, this study is now over 20 years old. The U.S. Nuclear Regulatory Commission requested that the National Academy of Sciences provide an updated assessment of cancer risks in populations near USNRC-licensed nuclear facilities that utilize or process uranium for the production of electricity. Analysis of Cancer Risks in Populations near Nuclear Facilities: Phase 1 focuses on identifying scientifically sound approaches for carrying out an assessment of cancer risks associated with living near a nuclear facility, judgments about the strengths and weaknesses of various statistical power, ability to assess potential confounding factors, possible biases, and required effort. The results from this Phase 1 study will be used to inform the design of cancer risk assessment, which will be carried out in Phase 2. This report is beneficial for the general public, communities near nuclear facilities, stakeholders, healthcare providers, policy makers, state and local officials, community leaders, and the media.

Cancer Epidemiology

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Author :
Publisher : IARC
ISBN 13 : 9789283204053
Total Pages : 466 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Cancer Epidemiology by : Isabel dos Santos Silva

Download or read book Cancer Epidemiology written by Isabel dos Santos Silva and published by IARC. This book was released on 1999 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: A basic textbook addressed to medical and public health students, clinicians, health professionals, and all others seeking to understand the principles and methods used in cancer epidemiology. Written by a prominent epidemiologist and experienced teacher at the London School of Hygiene and Tropical Medicine, the text aims to help readers become competent in the use of basic epidemiological tools and capable of exercising critical judgment when assessing results reported by others. Throughout the text, a lively writing style and numerous illustrative examples, often using real research data, facilitate an easy understanding of basic concepts and methods. Information ranges from an entertaining account of the origins of epidemiology, through advice on how to overcome some of the limitations of survival analysis, to a checklist of questions to ask when considering sources of bias. Although statistical concepts and formulae are presented, the emphasis is consistently on the interpretation of the data rather than on the actual calculations. The text has 18 chapters. The first six introduce the basic principles of epidemiology and statistics. Chapters 7-13 deal in more depth with each of the study designs and interpretation of their findings. Two chapters, concerned with the problems of confounding and study size, cover more complex statistical concepts and are included for advanced study. A chapter on methodological issues in cancer prevention gives examples of epidemiology's contribution to primary prevention, screening and other activities for early detection, and tertiary prevention. The concluding chapters review the role of cancer registries and discuss practical considerations that should be taken into account in the design, planning, and conduct of any type of epidemiological research.

Assessment of Cancer Screening

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Author :
Publisher : Springer Nature
ISBN 13 : 3030945774
Total Pages : 138 pages
Book Rating : 4.0/5 (39 download)

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Book Synopsis Assessment of Cancer Screening by : Pamela M. Marcus

Download or read book Assessment of Cancer Screening written by Pamela M. Marcus and published by Springer Nature. This book was released on 2022 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer screening is a prominent strategy in cancer control in the United States, yet the ability to correctly interpret cancer screening data eludes many researchers, clinicians, and policy makers. This open access primer rectifies that situation by teaching readers, in simple language and with straightforward examples, why and how the population-level cancer burden changes when screening is implemented, and how we assess whether that change is of benefit. This book provides an in-depth look at the many aspects of cancer screening and its assessment, including screening phenomena, performance measures, population-level outcomes, research designs, and other important and timely topics. Concise, accessible, and focused, Assessment of Cancer Screening: A Primer is best suited to those with education or experience in clinical research or public health in the United States - no previous knowledge of cancer screening assessment is necessary. This is the first text dedicated to cancer screening theory and methodology to be published in 20 years.