Clinician's Guide to Common Drug Interactions in Primary Care

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Publisher :
ISBN 13 : 9781651812181
Total Pages : 232 pages
Book Rating : 4.8/5 (121 download)

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Book Synopsis Clinician's Guide to Common Drug Interactions in Primary Care by : Eric Christianson

Download or read book Clinician's Guide to Common Drug Interactions in Primary Care written by Eric Christianson and published by . This book was released on 2020-02-05 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many, drug interactions are one of the most frustrating challenges in family medicine, geriatrics, and ambulatory care practice. Even if one is up to speed on what drugs interact with one another, it is often unknown how to manage that specific interaction. Throughout the book, I share some of my management tips and pearls to help you feel more comfortable with managing drug interactions. This book is a perfect piece of education for pharmacists, nurse practitioners, physicians, physician assistants, and nurses who are looking to pick up clinical, real-world practice pearls.

Meded101 Guide to Drug Food Interactions

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Publisher :
ISBN 13 :
Total Pages : 308 pages
Book Rating : 4.6/5 (649 download)

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Book Synopsis Meded101 Guide to Drug Food Interactions by : Eric Christianson

Download or read book Meded101 Guide to Drug Food Interactions written by Eric Christianson and published by . This book was released on 2020-07-16 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the perfect book for clinical rounds and internships! Food can significantly alter the concentrations of some medications. Alternatively, medications can contribute to nutritional deficiencies and other dietary complications. In this reference book, we lay out over 500 of the most commonly used medications and how they impact diet or how diet can alter the effects of drugs. This guide is designed to highlight important food and drug interactions with the most commonly used medications in clinical practice. In addition to highlighting potential food medication interactions, we have also laid out common adverse effects, indications, clinical pearls, mechanisms of action, and monitoring parameters that are critical for each medication. This is meant to be a quick reference for healthcare professionals and students who work in healthcare as dietitians, pharmacists, nurses, nurse practitioners, physicians, physician assistants, and others.

Drug Actions and Interactions

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Publisher : McGraw Hill Professional
ISBN 13 : 0071769455
Total Pages : 770 pages
Book Rating : 4.0/5 (717 download)

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Book Synopsis Drug Actions and Interactions by : Jae Y. Choe

Download or read book Drug Actions and Interactions written by Jae Y. Choe and published by McGraw Hill Professional. This book was released on 2011-03-04 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: The quick reference guide you need to avoid harmful interactions between prescription drugs, over-the-counter medications, and dietary supplements Drug Actions and Interactions is a handy easy-to-access guide to understanding what major drugs are available for specific diseases, how selected drugs produce therapeutic benefits, side effects that may occur when taking these drugs, and which drugs and supplements should not be taken in combination with each other. Applying the 300 most often prescribed drugs in the United States to more than 80 common disorders, Drug Actions and Interactions discusses each drug’s mechanism of action, side effects, and drug interactions. Molecular structures of medications are also included to help you understand their mechanisms of action. Coverage includes drugs that act on the major systems (cardiovascular, respiratory, gastrointestinal, genitourinary, endocrine, neuronal); bone, muscle, skin, and joints; and general health. You will also find an appendix listing major drugs currently in use in each therapeutic classification. Thirty-two additional appendices detail interaction between a therapeutic group of drugs and an individual drug or group of drugs, such as interactions of beta-blockers, alpha-blockers, calcium-blockers, etc.

Drug Interactions in Infectious Diseases

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Publisher : Springer Science & Business Media
ISBN 13 : 1617792136
Total Pages : 698 pages
Book Rating : 4.6/5 (177 download)

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Book Synopsis Drug Interactions in Infectious Diseases by : Stephen C. Piscitelli

Download or read book Drug Interactions in Infectious Diseases written by Stephen C. Piscitelli and published by Springer Science & Business Media. This book was released on 2011-09-08 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt: The revised and up-to-date third edition of Drug Interactions in Infectious Diseases delivers a text that will enhance your clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The third edition features five new chapters that cover material not addressed in previous editions. These new chapters describe interactions with a number of drug classes such as non-HIV antiviral, antimalarial, antiparasitic, antihelmintic, macrolide, azalide and ketolide agents. A novel chapter on probe cocktail studies has been included to highlight an important research tool for drug development. These chapters address material that cannot be retrieved easily in the medical literature. The highly acclaimed food-drug interactions as well as the study design and analysis chapters remain definitive references. The newly written drug-cytokine interaction highlights the need for our improved understanding of the complex interrelationship of acute infection, inflammation, and the risk of drug interactions. Informative tables on specific drug-drug interactions are provided throughout the chapters as a quick clinical resource. The Third Edition of Drug Interactions in Infectious Diseases is a distillation of relevant drug interactions associated with antimicrobials, infection, and inflammation. This concise review of the mechanisms and strategies to manage drug interactions should be valuable to all health care practitioners. Features • Definitive reference source of up-to-date information on antimicrobial drug interactions • Informative tables on the degree of interaction for specific antimicrobial agents • In-depth discussion of mechanisms and potential mechanistic pathways of interaction • New chapters on non-HIV antiviral, antimalarial, antiparasitic, and macrolide, azalide and ketolide agents • New chapter on probe-cocktail studies as a research tool to study drug-drug interactions • Inclusion of new antimicrobial agents and their associated drug interactions • First rate chapters on study design and analysis, and drug-food interactions • A fresh perspective on drug-cytokine interactions • Authoritative chapter on regulatory considerations of drug interactions during drug development

A Guide to Substance Abuse Services for Primary Care Clinicians

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Publisher :
ISBN 13 :
Total Pages : 194 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis A Guide to Substance Abuse Services for Primary Care Clinicians by : Eleanor J. Sullivan

Download or read book A Guide to Substance Abuse Services for Primary Care Clinicians written by Eleanor J. Sullivan and published by . This book was released on 1997 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: EXECUTIVE SUMMARY AND RECOMMENDATIONS: The goal of this TIP is to recommend guidelines for primary care clinicians to follow in caring for patients with alcohol and other drug use disorders. These guidelines were developed by a Consensus Panel of clinicians, researchers, and educators who work on the prevention and treatment of substance use disorders. Protocols are based partly on research evidence, partly on Panel members' clinical experience. The algorithm to the left follows a patient with substance use problems who presents in a primary care setting. The chart will serve as a guide or road map through screening, brief assessment, brief intervention, assessment, referral, specialized treatment, and followup care as they are detailed in the TIP. Since substance use disorders are often chronic conditions that progress slowly over time, primary care clinicians, through their regular, long-term contact with patients, are in an ideal position to screen for alcohol and drug problems and monitor each patient's status. Futhermore, studies have found that primary care clinicians can actually help many patients decrease alcohol consumption and its harmful consequences through office-based interventions that take only 10 to 15 minutes (Kahan et al., 1995; Wallace et al., 1988). This potential, however, is largely untapped: Saitz and colleagues found that of a sample of patients seeking substance abuse treatment, 45 percent reported that their primary care physician was unaware of their substance abuse (Saitz et al., in press). Yet even though screening and limited treatment of substance use disorders do not require a large time investment, the Consensus Panel that developed this TIP recognized that many primary care clinicians are already overwhelmed by the demands imposed by expanded gatekeeper functions. The Panel realized that a practical approach to addressing patients' substance abuse problems was needed: one that recognized the time and resource limitations inherent in primary care practice and offered a series of graduates approaches that could be incorporated into a normal clinic or office routine. Biological, medical, and genetic factors as well as psychological, social, familial, cultural, and other environmental features all bear on substance abuse. Addressing the condition effectively requires a team effort, especially when it has progressed beyond the early stage. For this reason, in addition to screening and intervention treatment options, these guidelines include information about viable referral for assessment and treatment, as well as followup. Readers will notice that the TIP contains more information on alcohol use and abuse than on use of illicit drugs. This reflects both the scope of the problems and the research literature available about them. It is estimated that about 18 million people with alcohol use problems and 5 million users of illicit drugs need treatment. Although the Panel recognizes that tobacco is an addictive substance with a major public health impact, it is not included in this TIP because the topic falls outside CSAT's purview. Readers are referred to "Smoking Cessation: a Guide for Primary Care Clinicians," published by the Agency for Health Care Policy and Research (Agency for Health Care Policy and Research, 1996). The Consensus Panel's recommendations are based on a combination of clinical experience and research-based evidence. In the list below, the summary guidelines supported by the research literature are followed by (1); clinically based recommendations are marked (2). Citations supporting the former are referenced in the body of the document. Screening and assessment instruments mentioned below are reproduced and discussed in Chapters 2 and 4 and Appendix C. The guidelines are presented in more detail in Chapter 6.

Handbook of Drug-Nutrient Interactions

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Publisher : Springer Science & Business Media
ISBN 13 : 160327362X
Total Pages : 823 pages
Book Rating : 4.6/5 (32 download)

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Book Synopsis Handbook of Drug-Nutrient Interactions by : Joseph I. Boullata

Download or read book Handbook of Drug-Nutrient Interactions written by Joseph I. Boullata and published by Springer Science & Business Media. This book was released on 2010-03-17 with total page 823 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Drug-Nutrient Interactions, Second Edition is an essential new work that provides a scientific look behind many drug-nutrient interactions, examines their relevance, offers recommendations, and suggests research questions to be explored. In the five years since publication of the first edition of the Handbook of Drug-Nutrient Interactions new perspectives have emerged and new data have been generated on the subject matter. Providing both the scientific basis and clinical relevance with appropriate recommendations for many interactions, the topic of drug-nutrient interactions is significant for clinicians and researchers alike. For clinicians in particular, the book offers a guide for understanding, identifying or predicting, and ultimately preventing or managing drug-nutrient interactions to optimize patient care. Divided into six sections all chapters have been revised or are new to this edition. Chapters balance the most technical information with practical discussions and include outlines that reflect the content; discussion questions that can guide the reader to the critical areas covered in each chapter, complete definitions of terms with the abbreviation fully defined and consistent use of terms between chapters. The editors have performed an outstanding service to clinical pharmacology and pharmaco-nutrition by bringing together a multi-disciplinary group of authors. Handbook of Drug-Nutrient Interactions, Second Edition is a comprehensive up-to-date text for the total management of patients on drug and/or nutrition therapy but also an insight into the recent developments in drug-nutrition interactions which will act as a reliable reference for clinicians and students for many years to come.

Advances in Patient Safety

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ISBN 13 :
Total Pages : 526 pages
Book Rating : 4.7/5 (54 download)

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Book Synopsis Advances in Patient Safety by : Kerm Henriksen

Download or read book Advances in Patient Safety written by Kerm Henriksen and published by . This book was released on 2005 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: v. 1. Research findings -- v. 2. Concepts and methodology -- v. 3. Implementation issues -- v. 4. Programs, tools and products.

Medication Therapy Management, Second Edition

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Publisher : McGraw Hill Professional
ISBN 13 : 1260143694
Total Pages : 654 pages
Book Rating : 4.2/5 (61 download)

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Book Synopsis Medication Therapy Management, Second Edition by : Karen Lynn Whalen

Download or read book Medication Therapy Management, Second Edition written by Karen Lynn Whalen and published by McGraw Hill Professional. This book was released on 2018-04-05 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Discover the medication therapy management solution—with this definitive, up-to-date sourcebook The need to improve the use of medications has major implications for the nation’s healthcare system. Burdened by high costs and an ineffective process of providing medication therapy, the current prescription drug environment poses considerable risks to patient safety. Medication therapy management (MTM) is designed to address these deficiencies—and this essential text gives pharmacists all the right MTM tools to identify and eliminate drug-related problems that can cause potentially severe adverse events. Medication Therapy Management delivers the most relevant insights into MTM—a vital service that is gaining momentum due to the rapid growth of patient-centered care, healthcare information technology, new practice models (e.g., Patient Centered Medical Home), and new payment methods. Cohesively organized, this expert-authored guide begins with an introduction to data sets for MTM, covering essential topics such as establishing quality and performance improvement, the payer perspective, conducting the comprehensive medication review, and reimbursement. The second part of Medication Therapy Management reviews MTM data sets for a wide spectrum of disorders, from asthma and atrial fibrillation to HIV and heart disease. Enhanced by the latest perspectives on therapeutics, including completely up-to-date tables throughout, Medication Therapy Management is a practical, skill-building roadmap for optimizing drug therapy and enhancing patient outcomes. Features • Everything you need to provide successful MTM services and empower patients to take an active role in their medication and overall healthcare • Turnkey disease-based data sets help you apply proven MTM principles to common disorders • Helpful appendices cover therapy management characteristics and answers to key questions; the MTM practice model and training survey; and the Medicare Part D MTM program standardized format

Top 300 Drugs Pocket Reference Guide (2024 Edition)

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Publisher : Coventry House Publishing
ISBN 13 :
Total Pages : 307 pages
Book Rating : 4./5 ( download)

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Book Synopsis Top 300 Drugs Pocket Reference Guide (2024 Edition) by : Coventry House Publishing

Download or read book Top 300 Drugs Pocket Reference Guide (2024 Edition) written by Coventry House Publishing and published by Coventry House Publishing. This book was released on 2024-07-23 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Top 300 Drugs Pocket Reference Guide serves as a portable reference to learn the essential information for the most commonly prescribed drugs. This on-the-go resource details the brand name, pharmacologic class, mechanism of action, dosage form, common use, and other clinical details for each drug. Whether you’re a pharmacy student or healthcare professional, this guide will serve as an effective resource to learn the basic characteristics of the most popular drugs. Drug details include: • Brand Names • Pharmacologic Classes • Mechanisms of Action • Common Uses • Dosage Forms • Dosing Information • Administration Methods • Monitoring Guidelines • Contraindications • Drug Interactions • Adverse Effects • Black Box Warnings

CDC Yellow Book 2018: Health Information for International Travel

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Publisher : Oxford University Press
ISBN 13 : 0190628634
Total Pages : 705 pages
Book Rating : 4.1/5 (96 download)

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Book Synopsis CDC Yellow Book 2018: Health Information for International Travel by : Centers for Disease Control and Prevention CDC

Download or read book CDC Yellow Book 2018: Health Information for International Travel written by Centers for Disease Control and Prevention CDC and published by Oxford University Press. This book was released on 2017-04-17 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.

Pharmacotherapy

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Publisher : Createspace Independent Publishing Platform
ISBN 13 : 9781514760697
Total Pages : 0 pages
Book Rating : 4.7/5 (66 download)

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Book Synopsis Pharmacotherapy by : Eric Christianson

Download or read book Pharmacotherapy written by Eric Christianson and published by Createspace Independent Publishing Platform. This book was released on 2015-06-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experience is the best teacher. Learn from someone who's been there. In this book, I share my real world experiences and scenarios as a clinical pharmacist to help you get a better grasp on medication management. I've been acknowledged in the Wall Street Journal, American Journal of Nursing, National Association Directors of Nursing, Pharmacy Times, and Pharmacy Today. My goal is to teach you clinical common sense when it comes to medications. If you are a healthcare professional (pharmacist, nurse, primary provider etc.) involved in medication management, this is a book full of clinical pearls, case studies, and medication mistakes that every healthcare professional should know. If you're passionate about learning more about polypharmacy, drug interactions, medication therapy management and common medication mistakes, you're going to love this book. Eric Christianson, PharmD, BCPS, CGP - Founder of meded101.com

Adverse Drug Interactions

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Publisher : CRC Press
ISBN 13 : 0429586337
Total Pages : 660 pages
Book Rating : 4.4/5 (295 download)

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Book Synopsis Adverse Drug Interactions by : Lakshman Delgoda Karalliedde

Download or read book Adverse Drug Interactions written by Lakshman Delgoda Karalliedde and published by CRC Press. This book was released on 2016-04-05 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adverse Drug Interactions: A Handbook for Prescribers assists clinicians by providing key information on potential adverse effects that can result from prescribing two or more drugs for simultaneous use. Interactions that are likely to give rise to life-threatening conditions, and which must therefore be completely avoided, are clearly highlighted.

The Thrill of the Case

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Publisher : Createspace Independent Publishing Platform
ISBN 13 : 9781721218899
Total Pages : 234 pages
Book Rating : 4.2/5 (188 download)

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Book Synopsis The Thrill of the Case by : Eric Christianson

Download or read book The Thrill of the Case written by Eric Christianson and published by Createspace Independent Publishing Platform. This book was released on 2018-06-30 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical pharmacology is often one of the most challenging topics for healthcare professionals. This is a compilation of my favorite case scenarios, drug interactions and clinical pearls from my practice as a clinical pharmacist. This book is a perfect piece of education for pharmacists, nurse practitioners, physicians, physician assistants, and nurses who are looking to pick up clinical practice pearls about medication management. It is ideal for the new professional or student trying to gain more confidence when it comes to medication management.

Frequently Prescribed Medications

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Publisher : Jones & Bartlett Learning
ISBN 13 : 0763781177
Total Pages : 272 pages
Book Rating : 4.7/5 (637 download)

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Book Synopsis Frequently Prescribed Medications by : Michael Mancano

Download or read book Frequently Prescribed Medications written by Michael Mancano and published by Jones & Bartlett Learning. This book was released on 2010-11-12 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Health Sciences & Professions

The Top 100 Drugs

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Publisher : Elsevier
ISBN 13 : 9780323834452
Total Pages : 336 pages
Book Rating : 4.8/5 (344 download)

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Book Synopsis The Top 100 Drugs by : Andrew Hitchings

Download or read book The Top 100 Drugs written by Andrew Hitchings and published by Elsevier. This book was released on 2022-11 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its third edition, this small and accessible guide contains essential information for the safe prescribing of the most commonly used drugs in the NHS. The Top 100 Drugs combines the best elements of a students' textbook with those of a prescribers' manual. It gives equal weight to essential information on the science of pharmacology as well as the real-world practicalities of prescribing, all in an accessible and clear format. Written by leaders in the field of clinical pharmacology, this popular book has been fully revised and updated to include the drugs used today, including monoclonal antibodies and antiviral drugs for COVID-19. With common indications, mechanism of action, adverse effects, important interactions and a clinical tip for each drug as well as questions to test knowledge, this book is key to helping students understand everything they need to know about the drugs they are likely to use in practice. Compact and easy to follow - can be carried around on the wards Logically ordered - offers multiple ways to find the drug you are looking for A Clinical Tip for each drug, drawn from the authors' experience 100 self-assessment questions to encourage integration and revision of knowledge and understanding Fully updated to include the most commonly prescribed drugs today, based on original research led by the authors of over 1 billion community prescriptions and approximately 1 million hospital prescriptions All drug monographs extensively reviewed and updated Dedicated section emergency drugs Updated self-assessment material, now including calculation and prescription-writing questions, in addition to single-best-answer questions

Clinical Handbook of Psychotropic Drugs for Children and Adolescents

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Publisher :
ISBN 13 : 9780889375505
Total Pages : 362 pages
Book Rating : 4.3/5 (755 download)

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Book Synopsis Clinical Handbook of Psychotropic Drugs for Children and Adolescents by : Dean Elbe

Download or read book Clinical Handbook of Psychotropic Drugs for Children and Adolescents written by Dean Elbe and published by . This book was released on 2019-01-21 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: New in this edition:¿ Drugs for ADHD thoroughly revised and updated¿ Antipsychotics with many changes and additions, including fully revised lab tests/monitoring¿ Antidepressants fully revised, including new sections on irreversible MAO-B inhibitor and serotonin modulator and stimulator (SMS), revised frequency of adverse effects table and switching strategies recommendations¿ Hypnotics completely revised¿ Mood stabilizers fully revised and a new toxicity comparison table added¿ Drugs of abuse and treatment of substance use disorder comprehensively revised¿ New unapproved treatments with significant updates, including: anti-inflammatories and NMDA agents in anxiety/OCD, cannabis use, and irritability of autism¿ New agents include: brexpiprazole, cariprazine, hypnotic suvorexant, tasimelteon, vortioxetine¿ New formulations and trade names include: Adasuve, Alprazolam Intensol, Aptensio XR, Aristada, Belbuca, Belsomra, Brintellix, Bunavail, Cotempla XR-ODT, Dyanavel XR, Eldepryl, EMSAM, Evekeo, Hemangeol, Hetlioz, Innopran XL, Invega Trinza, Khedezla, Metadol-D, Mydayis, NyQuil, Quillichew ER, Quillivant XR, Rexulti, Som-Pam, Tegretol (liquid), Trintellix, Versacolz, Vraylar, Vyvanse, Zelapar, ZenzediThe Clinical Handbook of Psychotropic Drugs for Children and Adolescents has become a standard reference and working tool for psychiatrists, pediatricians, psychologists, physicians, pharmacists, nurses, and other mental health professionals.¿ Packed with unique, easy-to-read comparison charts and tables (dosages, side effects, pharmacokinetics, interactions¿) for a quick overview of treatment options¿ Succinct, bulleted information on all classes of medication: on- and off-label indications, side effects, interactions, pharmacodynamics, nursing implications, and much more - all you need to know for each class of drug¿ Potential interactions and side effects summarized in comparison charts¿ With instantly recognizable icons and in full color throughout, allowing you to find at a glance all the information you seek¿ Clearly written patient and caregiver information sheets for download as printable PDF filesThis book is a must for all mental health professionals working with children and adolescents who need an up-to-date, easy-to use, comprehensive summary of all the most relevant information about psychotropic drugs.

Pain Management and the Opioid Epidemic

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Author :
Publisher : National Academies Press
ISBN 13 : 0309459575
Total Pages : 483 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Pain Management and the Opioid Epidemic by : National Academies of Sciences, Engineering, and Medicine

Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.