Cross-over Trials in Clinical Research

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Publisher : John Wiley & Sons
ISBN 13 : 0470854588
Total Pages : 364 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis Cross-over Trials in Clinical Research by : Stephen S. Senn

Download or read book Cross-over Trials in Clinical Research written by Stephen S. Senn and published by John Wiley & Sons. This book was released on 2003-07-25 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cross-over trials are an important class of design used in the pharmaceutical industry and medical research, and their use continues to grow. Cross-over Trials in Clinical Research, Second Edition has been fully updated to include the latest methodology used in the design and analysis of cross-over trials. It includes more background material, greater coverage of important statistical techniques, including Bayesian methods, and discussion of analysis using a number of statistical software packages. * Comprehensive coverage of the design and analysis of cross-over trials. * Each technique is carefully explained and the mathematics is kept to a minimum. * Features many real and original examples, taken from the author's vast experience. * Includes discussion of analysis using SAS, S-Plus and, GenStat, StatXact and Excel. * Written in a style suitable for statisticians and physicians alike. * Computer programs to accompany the examples in the book can be downloaded from the Web Primarily aimed at statisticians and researchers working in the pharmaceutical industry, the book will also appeal to physicians involved in clinical research and students of medical statistics.

Women and Health Research

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Author :
Publisher : National Academies Press
ISBN 13 : 030904992X
Total Pages : 286 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Women and Health Research by : Institute of Medicine

Download or read book Women and Health Research written by Institute of Medicine and published by National Academies Press. This book was released on 1994-02-01 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the nineteenth century some scientists argued that women should not be educated because thinking would use energy needed by the uterus for reproduction. The proof? Educated women had a lower birth rate. Today's researchers can only shake their heads at such reasoning. Yet professional journals and the popular press are increasingly criticizing medical research for ignoring women's health issues. Women and Health Research examines the facts behind the public's perceptions about women participating as subjects in medical research. With the goal of increasing researchers' awareness of this important topic, the book explores issues related to maintaining justice (in its ethical sense) in clinical studies. Leading experts present general principles for the ethical conduct of research on womenâ€"principles that are especially important in the light of recent changes in federal policy on the inclusion of women in clinical research. Women and Health Research documents the historical shift from a paternalistic approach by researchers toward women and a disproportionate reliance on certain groups for research to one that emphasizes proper access for women as subjects in clinical studies in order to ensure that women receive the benefits of research. The book addresses present-day challenges to equity in four areas: Scientificâ€"Do practical aspects of scientific research work at cross-purposes to gender equity? Focusing on drug trials, the authors identify rationales for excluding people from research based on demographics. Social and Ethicalâ€"The authors offer compelling discussions on subjectivity in science, the evidence for male bias, and issues related to race and ethnicity, as well as the recruitment, retention, and protection of research participants. Legalâ€"Women and Health Research reviews federal research policies that affect the inclusion of women and evaluates the basis for researchers' fears about liability, citing court cases. Riskâ€"The authors focus on risks to reproduction and offspring in clinical drug trials, exploring how risks can be identified for study participants, who should make the assessment of risk and benefit for participation in a clinical study, and how legal implications could be addressed. This landmark study will be of immediate use to the research community, policymakers, women's health advocates, attorneys, and individuals.

Clinical Studies, Vol. 2

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Publisher : Forgotten Books
ISBN 13 : 9780364411575
Total Pages : 588 pages
Book Rating : 4.4/5 (115 download)

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Book Synopsis Clinical Studies, Vol. 2 by : John Rose Cormack

Download or read book Clinical Studies, Vol. 2 written by John Rose Cormack and published by Forgotten Books. This book was released on 2018-03-12 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: Excerpt from Clinical Studies, Vol. 2: Illustrated by Cases Observed in Hospital and Private Practice On the Cause of the Entrance of Air into Veins divided during operation; with some Considerations on the Means most likely to Avert Death in such cases. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.

Women and Health Research

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Publisher :
ISBN 13 :
Total Pages : 268 pages
Book Rating : 4.3/5 (97 download)

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Book Synopsis Women and Health Research by : Anna C. Mastroianni

Download or read book Women and Health Research written by Anna C. Mastroianni and published by . This book was released on 1994 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Women and Health Research

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Author :
Publisher : National Academies Press
ISBN 13 : 0309050405
Total Pages : 262 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Women and Health Research by : Institute of Medicine

Download or read book Women and Health Research written by Institute of Medicine and published by National Academies Press. This book was released on 1994-02-01 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a growing perception that biomedical research has focused more on the health problems of men relative to those of women and that women have been denied access to advances in medical diagnosis and therapy as a result of being excluded from clinical studies. Women and Health Research, Volume 2, addresses issues connected with women's participation in clinical studies: ethical issues related to recruitment, retention, and the inclusion of pregnant women and other women of childbearing age; legal issues such as liability, compensation for injury, constitutional concerns, and federal regulations; and health consequences associated with exclusion or underrepresentation. The commissioned papers focus on the research participation of women from specific racial and ethnic groups and on whether women have been underrepresented in biomedical research, based on a systematic survey of clinical studies reported in a prominent medical journal.

Women and Health Research

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Author :
Publisher : National Academies Press
ISBN 13 : 030958650X
Total Pages : 262 pages
Book Rating : 4.3/5 (95 download)

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Book Synopsis Women and Health Research by : Committee on the Ethical and Legal Issues Relating to the Inclusion of Women in Clinical Studies

Download or read book Women and Health Research written by Committee on the Ethical and Legal Issues Relating to the Inclusion of Women in Clinical Studies and published by National Academies Press. This book was released on 1994-01-15 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a growing perception that biomedical research has focused more on the health problems of men relative to those of women and that women have been denied access to advances in medical diagnosis and therapy as a result of being excluded from clinical studies. Women and Health Research, Volume 2, addresses issues connected with women's participation in clinical studies: ethical issues related to recruitment, retention, and the inclusion of pregnant women and other women of childbearing age; legal issues such as liability, compensation for injury, constitutional concerns, and federal regulations; and health consequences associated with exclusion or underrepresentation. The commissioned papers focus on the research participation of women from specific racial and ethnic groups and on whether women have been underrepresented in biomedical research, based on a systematic survey of clinical studies reported in a prominent medical journal.

Bayesian Adaptive Methods for Clinical Trials

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Publisher : CRC Press
ISBN 13 : 1439825513
Total Pages : 316 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Bayesian Adaptive Methods for Clinical Trials by : Scott M. Berry

Download or read book Bayesian Adaptive Methods for Clinical Trials written by Scott M. Berry and published by CRC Press. This book was released on 2010-07-19 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Already popular in the analysis of medical device trials, adaptive Bayesian designs are increasingly being used in drug development for a wide variety of diseases and conditions, from Alzheimer's disease and multiple sclerosis to obesity, diabetes, hepatitis C, and HIV. Written by leading pioneers of Bayesian clinical trial designs, Bayesian Adapti

Bayesian Approaches to Clinical Trials and Health-Care Evaluation

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Publisher : John Wiley & Sons
ISBN 13 : 9780471499756
Total Pages : 416 pages
Book Rating : 4.4/5 (997 download)

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Book Synopsis Bayesian Approaches to Clinical Trials and Health-Care Evaluation by : David J. Spiegelhalter

Download or read book Bayesian Approaches to Clinical Trials and Health-Care Evaluation written by David J. Spiegelhalter and published by John Wiley & Sons. This book was released on 2004-01-16 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: READ ALL ABOUT IT! David Spiegelhalter has recently joined the ranks of Isaac Newton, Charles Darwin and Stephen Hawking by becoming a fellow of the Royal Society. Originating from the Medical Research Council’s biostatistics unit, David has played a leading role in the Bristol heart surgery and Harold Shipman inquiries. Order a copy of this author’s comprehensive text TODAY! The Bayesian approach involves synthesising data and judgement in order to reach conclusions about unknown quantities and make predictions. Bayesian methods have become increasingly popular in recent years, notably in medical research, and although there are a number of books on Bayesian analysis, few cover clinical trials and biostatistical applications in any detail. Bayesian Approaches to Clinical Trials and Health-Care Evaluation provides a valuable overview of this rapidly evolving field, including basic Bayesian ideas, prior distributions, clinical trials, observational studies, evidence synthesis and cost-effectiveness analysis. Covers a broad array of essential topics, building from the basics to more advanced techniques. Illustrated throughout by detailed case studies and worked examples Includes exercises in all chapters Accessible to anyone with a basic knowledge of statistics Authors are at the forefront of research into Bayesian methods in medical research Accompanied by a Web site featuring data sets and worked examples using Excel and WinBUGS - the most widely used Bayesian modelling package Bayesian Approaches to Clinical Trials and Health-Care Evaluation is suitable for students and researchers in medical statistics, statisticians in the pharmaceutical industry, and anyone involved in conducting clinical trials and assessment of health-care technology.

Missing Data in Clinical Studies

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Publisher : John Wiley & Sons
ISBN 13 : 9780470510438
Total Pages : 526 pages
Book Rating : 4.5/5 (14 download)

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Book Synopsis Missing Data in Clinical Studies by : Geert Molenberghs

Download or read book Missing Data in Clinical Studies written by Geert Molenberghs and published by John Wiley & Sons. This book was released on 2007-04-04 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Missing Data in Clinical Studies provides a comprehensive account of the problems arising when data from clinical and related studies are incomplete, and presents the reader with approaches to effectively address them. The text provides a critique of conventional and simple methods before moving on to discuss more advanced approaches. The authors focus on practical and modeling concepts, providing an extensive set of case studies to illustrate the problems described. Provides a practical guide to the analysis of clinical trials and related studies with missing data. Examines the problems caused by missing data, enabling a complete understanding of how to overcome them. Presents conventional, simple methods to tackle these problems, before addressing more advanced approaches, including sensitivity analysis, and the MAR missingness mechanism. Illustrated throughout with real-life case studies and worked examples from clinical trials. Details the use and implementation of the necessary statistical software, primarily SAS. Missing Data in Clinical Studies has been developed through a series of courses and lectures. Its practical approach will appeal to applied statisticians and biomedical researchers, in particular those in the biopharmaceutical industry, medical and public health organisations. Graduate students of biostatistics will also find much of benefit.

Advances in Patient Safety

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Publisher :
ISBN 13 :
Total Pages : 526 pages
Book Rating : 4.7/5 (54 download)

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Book Synopsis Advances in Patient Safety by : Kerm Henriksen

Download or read book Advances in Patient Safety written by Kerm Henriksen and published by . This book was released on 2005 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: v. 1. Research findings -- v. 2. Concepts and methodology -- v. 3. Implementation issues -- v. 4. Programs, tools and products.

Adults: A Sourcebook

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Publisher : Simon and Schuster
ISBN 13 : 0029066867
Total Pages : 776 pages
Book Rating : 4.0/5 (29 download)

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Book Synopsis Adults: A Sourcebook by : Joel Fischer

Download or read book Adults: A Sourcebook written by Joel Fischer and published by Simon and Schuster. This book was released on 1994 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now, this updated and expanded two-volume edition of Fischer and Corcoran's standard reference enables professionals to gather this vital information easily and effectively. In Measures for Clinical Practice, Volume 1: Couples, Families and Children and Volume 2: Adults, Joel Fischer and Kevin Corcoran provide an extensive collection of over 320 "rapid assessment instruments" (RAIs), including questionnaires and scales, which assess virtually any problem commonly encountered in clinical practice. All instruments are actually reprinted in the book, and are critiqued by the authors to aid in their selection. The instruments included are brief and easy to administer and will be useful for all types of practice and all theoretical orientations.

Fundamental Concepts in Clinical Research Vol- 2

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Publisher :
ISBN 13 :
Total Pages : 196 pages
Book Rating : 4.6/5 (891 download)

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Book Synopsis Fundamental Concepts in Clinical Research Vol- 2 by : Priyadarsh Vasanthan

Download or read book Fundamental Concepts in Clinical Research Vol- 2 written by Priyadarsh Vasanthan and published by . This book was released on 2020-09-22 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook is written specifically for medical students and first-time learners of clinical research methods. Alongside the textbook is the workbook that is designed to teach the major fundamental concepts of clinical data management, role of statistics in clinical trials, medical writing and regulatory submission, drug safety and pharmacovigilance. It is written in concise and organized fashion with many examples to illustrate the concepts deriving from a collection of written materials created to teach students in easy manner. The textbook is made to provide students with the tools necessary to form their own informed conclusions from the clinical research literature.This easy-to-read guide is available to help students develop a good study design and present evidence of a sound academic practice, which will make obtaining fundamental more likely to be time-efficient. Getting started early in research and developing a solid, gradual understanding of clinical research through using this approachable book will be of huge benefit to students.

Publishing Your Medical Research

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1496353870
Total Pages : 392 pages
Book Rating : 4.4/5 (963 download)

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Book Synopsis Publishing Your Medical Research by : Daniel W. Byrne

Download or read book Publishing Your Medical Research written by Daniel W. Byrne and published by Lippincott Williams & Wilkins. This book was released on 2016-08-03 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publishing Your Medical Research is the second edition of the award-winning book that provides practical information on how to write a publishable paper. This edition includes additional details to help medical researchers succeed in the competitive “publish or perish” world. Using a direct and highly informative style, it does more than help you write a paper; it presents the technical information, invaluable modern advice, and practical tips you need to get your paper accepted for publication. A singular source for the beginning and experienced researcher alike, Publishing Your Medical Research is a must for any physician, fellow, resident, medical scientist, graduate student, or biostatistician seeking to be published.

Textbook of Clinical Trials

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Publisher : John Wiley & Sons
ISBN 13 : 0470010150
Total Pages : 784 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Textbook of Clinical Trials by : David Machin

Download or read book Textbook of Clinical Trials written by David Machin and published by John Wiley & Sons. This book was released on 2007-01-11 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now published in its Second Edition, the Textbook of Clinical Trials offers detailed coverage of trial methodology in diverse areas of medicine in a single comprehensive volume. Praise for the First Edition: "... very useful as an introduction to clinical research, or for those planning specific studies within therapeutic or disease areas." BRITISH JOURNAL OF SURGERY, Vol. 92, No. 2, February 2005 The book’s main concept is to describe the impact of clinical trials on the practice of medicine. It separates the information by therapeutic area because the impact of clinical trials, the problems encountered, and the numbers of trials in existence vary tremendously from specialty to specialty. The sections provide a background to the disease area and general clinical trial methodology before concentrating on particular problems experienced in that area. Specific examples are used throughout to address these issues. The Textbook of Clinical Trials, Second Edition: Highlights the various ways clinical trials have influenced the practice of medicine in many therapeutic areas Describes the challenges posed by those conducting clinical trials over a range of medical specialities and allied fields Additional therapeutic areas are included in this Second Edition to fill gaps in the First Edition as the number and complexity of trials increases in this rapidly developing area Newly covered or updated in the Second Edition: general surgery, plastic surgery, aesthetic surgery, palliative care, primary care, anaesthesia and pain, transfusion, wound healing, maternal and perinatal health, early termination, organ transplants, ophthalmology, epilepsy, infectious disease, neuro-oncology, adrenal, thyroid and urological cancers, as well as a chapter on the Cochrane network An invaluable resource for pharmaceutical companies, the Textbook of Clinical Trials, Second Edition appeals to those working in contract research organizations, medical departments and in the area of public health and health science alike.

Clinical Studies in Extracorporeal Circulation

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Publisher :
ISBN 13 : 9780964323315
Total Pages : 240 pages
Book Rating : 4.3/5 (233 download)

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Book Synopsis Clinical Studies in Extracorporeal Circulation by : J.M. Toomasian

Download or read book Clinical Studies in Extracorporeal Circulation written by J.M. Toomasian and published by . This book was released on 1996 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Natural Products in Clinical Trials: Volume 2

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Publisher : Bentham Science Publishers
ISBN 13 : 9811425752
Total Pages : 280 pages
Book Rating : 4.8/5 (114 download)

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Book Synopsis Natural Products in Clinical Trials: Volume 2 by : Atta-ur-Rahman

Download or read book Natural Products in Clinical Trials: Volume 2 written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2020-08-20 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural compounds continue to play a key role in drug development. Many clinically approved drugs are either unmodified natural products or their semi-synthetic derivatives. This book series presents reviews of exciting new bioactive natural products that have huge potential as drugs. Each volume presents comprehensive chapters contributed by eminent scientists. The volumes focus on drug candidates which are in the later stages of drug development and are being evaluated in clinical trials. The series, therefore, highlights the importance of natural products in our lives. The second volume covers the following topics: - A review of recent patents and natural products in clinical trials to treat schistosomiasis - Natural products: the new intervention regimen for metabolic disorders - Fluorine-containing drugs and drug candidates derived from natural products - Natural products for the management of cardiovascular diseases - Implication of natural compounds for the prevention of ocular diseases.

APA Handbook of Clinical Psychology

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Publisher :
ISBN 13 : 9781433821325
Total Pages : pages
Book Rating : 4.8/5 (213 download)

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Book Synopsis APA Handbook of Clinical Psychology by : John C. Norcross

Download or read book APA Handbook of Clinical Psychology written by John C. Norcross and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: