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Author : William Waggoner
Publisher : CRC Press
ISBN 13 : 9780824779412
Total Pages : 350 pages
Book Rating : 4.7/5 (794 download)
Download or read book Clinical Safety and Efficacy Testing of Cosmetics written by William Waggoner and published by CRC Press. This book was released on 1989-11-27 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : P. Elsner
Publisher : Springer Science & Business Media
ISBN 13 : 3642598692
Total Pages : 325 pages
Book Rating : 4.6/5 (425 download)
Download or read book Cosmetics written by P. Elsner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: th Together with the 6 Amendment - Council Directive 93/35 EEC - to the Cosmetic Directive 76/768 EEC it was the first time that, according to Article 7b, special claims of efficacy could be legally attributed to cosmetic products but under the obligation to make evidence of the claimed effects; also an entirely new "controller" was introduced - the independent "safety assessor", This indeed means not only progress in reliable and honest marketing arguments but above all transparency as to the respective proof and thus protection of consumer's health. Such claims demand high standards in scientifi cally based methodology and their results in order to prove such demands evidently. There are also within the 6" Amendment to the Cosmetic Directive in Article 4a strict restrictions as to the further use of conventional animal testing for cosmetic pro ducts and their ingredients and especially for finished products. Without doubt there is a competition between the necessity and expectations on consumer health on the one hand and the requirements of acknowledged protection of animals as done in Council Directive 86/609 EEC on the other. But at least, based on the present state of knowledge, tests in human beings cannot replace animal testing in all instances. Not only ethical reasons alone prohibit or impede testing in humans but also very often the lack of knowledge on functional and/or biological processes underlaying observed effects with the consequence that suitable experimental methodologies are missing.
Author : Joachim W. Fluhr
Publisher : Springer Science & Business Media
ISBN 13 : 3642050670
Total Pages : 262 pages
Book Rating : 4.6/5 (42 download)
Download or read book Practical Aspects of Cosmetic Testing written by Joachim W. Fluhr and published by Springer Science & Business Media. This book was released on 2010-11-10 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Skin physiology assessment is moving rapidly from a descriptive approach to a deeper understanding of biophysical and biochemical processes in the stratum corneum, e.g. on stratum corneum barrier function as well on stratum corneum hydration. The research with bioengineering methods offers now reliable and reproducible approaches for product testing in the pharmaceutical and cosmetic industry as well as in basic research. This cookbook is intended to give basic information regarding skin physiology, the assessment of skin functions in controlled studies using non-invasive biophysical instruments. It provides basic knowledge on how to plan, perform and evaluate scientific studies. The authors are recognized expert in the field and provide comprehensive chapters with specific emphasis on the practical aspects of non-invasive measurements.
Author : Albert M. Kligman
Publisher : Saunders
ISBN 13 : 9780808915270
Total Pages : 411 pages
Book Rating : 4.9/5 (152 download)
Download or read book Safety and Efficacy of Topical Drugs and Cosmetics written by Albert M. Kligman and published by Saunders. This book was released on 1982 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Joachim W. Fluhr
Publisher : Springer Nature
ISBN 13 : 303044967X
Total Pages : 309 pages
Book Rating : 4.0/5 (34 download)
Download or read book Practical Aspects of Cosmetic Testing written by Joachim W. Fluhr and published by Springer Nature. This book was released on 2020-07-07 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Skin physiology assessment is moving from a descriptive approach to a deeper understanding of biophysical and biochemical processes in the stratum corneum, such as epidermal barrier function and stratum corneum hydration. New, non-invasive approaches offer reliable and reproducible methods for product testing in the pharmaceutical and cosmetic industry, as well as in basic research. While standard instruments focus on functional aspects, innovative devices offer a deeper understanding of underlying mechanisms. This book discusses the assessment of skin physiology and of skin functions in clinical studies using non-invasive biophysical instruments, offering readers a comprehensive guide to planning, performing and evaluating the results of scientific studies in skin measurement and the legal framework for these studies. Written by leading experts in the field, it focuses on practical aspects of non-invasive measurements. After introducing the legal aspects of the current framework for clinical cosmetic studies and basic research in cosmetology, it explores the technical practicalities of organizing a testing lab and the pre-requirements for planning a study. The third and main section addresses specific topics in cosmetic testing e.g. skin hydration, and also includes chapters on sensory aspects and in vivo skin structure vizualization. This new, updated edition of Practical Aspects of Cosmetic Testing is a valuable tool for researchers, students, and medical staff wanting to gain insights into how best to assess skin functions in controlled studies using non-invasive biophysical instruments.
Author : Harry Salem
Publisher : CRC Press
ISBN 13 : 9781560326236
Total Pages : 456 pages
Book Rating : 4.3/5 (262 download)
Download or read book Advances In Animal Alternatives For Safety And Efficacy Testing written by Harry Salem and published by CRC Press. This book was released on 1997-11-12 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents up-to-date concepts and approaches to the theory and practice of alternatives to animal testing and promotes technology transfer. The text addresses some of the ramifications of the National Institutes of Health Revitalization Act of 1993 which instructs the NIH to fund replacement, reduction and refinement alternatives. It also describes the likely impact of the European Union's Cosmetic Directive, which bans marketing of animal tested cosmetics in Europe after 1997 if alternatives are available. Contributions are grouped into five categories including: dermal toxicity; immunotoxicity; neurotoxicity; and oral/dermal/ocular validation.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309101174
Total Pages : 23 pages
Book Rating : 4.3/5 (91 download)
Download or read book Science, Medicine, and Animals written by National Research Council and published by National Academies Press. This book was released on 2006-02-19 with total page 23 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science, Medicine, and Animals explains the role that animals play in biomedical research and the ways in which scientists, governments, and citizens have tried to balance the experimental use of animals with a concern for all living creatures. An accompanying Teacher's Guide is available to help teachers of middle and high school students use Science, Medicine, and Animals in the classroom. As students examine the issues in Science, Medicine, and Animals, they will gain a greater understanding of the goals of biomedical research and the real-world practice of the scientific method in general. Science, Medicine, and Animals and the Teacher's Guide were written by the Institute for Laboratory Animal Research and published by the National Research Council of the National Academies. The report was reviewed by a committee made up of experts and scholars with diverse perspectives, including members of the U.S. Department of Agriculture, National Institutes of Health, the Humane Society of the United States, and the American Society for the Prevention of Cruelty to Animals. The Teacher's Guide was reviewed by members of the National Academies' Teacher Associates Network. Science, Medicine, and Animals is recommended by the National Science Teacher's Association NSTA Recommends.
Author : Vera Rogiers
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805586558
Total Pages : 235 pages
Book Rating : 4.8/5 (55 download)
Download or read book Safety Assessment of Cosmetics in Europe written by Vera Rogiers and published by Karger Medical and Scientific Publishers. This book was released on 2008 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Current Problems in Dermatology presents the reader with a portrait of the scientific background of the complex process of safety assessment of cosmetics as well as information on European cosmetic legislation. A practical approach to the search for toxicity data on cosmetic ingredients and a compilation of the legally required technical dossier of a finished cosmetic product as well as an in-depth analysis of the safety assessment of cosmetic ingredients performed at the EU level by the Scientific Committee on Consumer Products (SCCP) are available. The current status of 3R alternatives to animal testing and the extent to which they are implemented by the cosmetic industry and considered by the SCCP in the risk assessment process is discussed. As such, guidance is provided in relation to the manifold challenges cosmetic safety assessors are faced with in the current EU regulatory setting.In this valuable handbook, qualified cosmetic safety assessors, suppliers of raw materials, dermatologists and pharmacists, toxicologists as well as EU officials and administrators dealing with cosmetics will find relevant information on the European cosmetic legislation, the compilation of cosmetic technical dossiers, toxicological database searches, and the availability and use of alternative methods in the field of cosmetics.
Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309042860
Total Pages : 241 pages
Book Rating : 4.3/5 (9 download)
Download or read book Modern Methods of Clinical Investigation written by Institute of Medicine and published by National Academies Press. This book was released on 1990-02-01 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: The very rapid pace of advances in biomedical research promises us a wide range of new drugs, medical devices, and clinical procedures. The extent to which these discoveries will benefit the public, however, depends in large part on the methods we choose for developing and testing them. Modern Methods of Clinical Investigation focuses on strategies for clinical evaluation and their role in uncovering the actual benefits and risks of medical innovation. Essays explore differences in our current systems for evaluating drugs, medical devices, and clinical procedures; health insurance databases as a tool for assessing treatment outcomes; the role of the medical profession, the Food and Drug Administration, and industry in stimulating the use of evaluative methods; and more. This book will be of special interest to policymakers, regulators, executives in the medical industry, clinical researchers, and physicians.
Author : Ralph G. Harry
Publisher :
ISBN 13 : 9781258763527
Total Pages : 902 pages
Book Rating : 4.7/5 (635 download)
Download or read book Cosmetics written by Ralph G. Harry and published by . This book was released on 2013-06 with total page 902 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309038391
Total Pages : 113 pages
Book Rating : 4.3/5 (9 download)
Download or read book Use of Laboratory Animals in Biomedical and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.
Author : Louise Aust
Publisher : CRC Press
ISBN 13 : 1482234149
Total Pages : 281 pages
Book Rating : 4.4/5 (822 download)
Download or read book Cosmetic Claims Substantiation written by Louise Aust and published by CRC Press. This book was released on 1997-10-06 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shows how to validate scientifically the marketing claims of chemically stable and well-balanced products to withstand adequately the challenge of competitors and government regulators. The book describes techniques for substantiating properties, such as moisturization, mildness, conditioning and cleansing, as well as the performance of deodorants
Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309183642
Total Pages : 135 pages
Book Rating : 4.3/5 (91 download)
Download or read book Rational Therapeutics for Infants and Children written by Institute of Medicine and published by National Academies Press. This book was released on 2000-04-07 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Institute of Medicine's (IOM's) Roundtable on Research and Development of Drugs, Biologics, and Medical Devices evolved from the Forum on Drug Development, which was established in 1986. Sponsor representatives and IOM determined the importance of maintaining a neutral setting for discussions regarding long-term and politically sensitive issues justified the need to revise and enhance past efforts. The new Roundtable is intended to be a mechanism by which a broad group of experts from the public* and private sectors can be convened to conduct a dialogue and exchange information related to the development of drugs, biologics, and medical devices. Members have expertise in clinical medicine, pediatrics, clinical pharmacology, health policy, health insurance, industrial management, and product development; and they represent interests that address all facets of public policy issues. From time to time, the Roundtable requests that a workshop be conducted for the purpose of exploring a specific topic in detail and obtaining the views of additional experts. The first workshop for the Roundtable was held on April 14 and 15, 1998, and was entitled Assuring Data Quality and Validity in Clinical Trials for Regulatory Decision Making. The summary on that workshop is available from IOM. This workshop summary covers the second workshop, which was held on May 24 and 25, 1999, and which was aimed at facilitating the development and proper use of drugs, biologics, and medical devices for infants and children. It explores the scientific underpinnings and clinical needs, as well as the regulatory, legal, and ethical issues, raised by this area of research and development.
Author : André Barel
Publisher : CRC Press
ISBN 13 : 0849354838
Total Pages : 1034 pages
Book Rating : 4.8/5 (493 download)
Download or read book Handbook of Cosmetic Science and Technology written by André Barel and published by CRC Press. This book was released on 2005-11-04 with total page 1034 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ranging from studies on the structure and function of the skin to research on a wide array of cosmetic compounds, this Second Edition updates readers on the latest regulatory guidelines, new cosmetic ingredients, state-of-the-art safety assessment technologies, and anticipated trends in the market-keeping pace with rapid advancements in chemistry,
Author : Robert L. Rietschel
Publisher : CRC Press
ISBN 13 : 9780824782641
Total Pages : 258 pages
Book Rating : 4.7/5 (826 download)
Download or read book Methods for Cutaneous Investigation written by Robert L. Rietschel and published by CRC Press. This book was released on 1990-04-27 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Karl Laden
Publisher : CRC Press
ISBN 13 : 9780824717469
Total Pages : 430 pages
Book Rating : 4.7/5 (174 download)
Download or read book Antiperspirants and Deodorants, Second Edition, written by Karl Laden and published by CRC Press. This book was released on 1999-01-04 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a review of the most recent advances in the science and technology of controlling odour and wetness. This edition includes two new chapters on antiperspirant and deodorant formulations; two new chapters on relevant patent technologies of recent years; discussions on the chemistry of aluminium/zirconium antiperspirant salts; and a modernized chapter on the structure and function of the human eccrine sweat glands.
Author : Eric Jungermann
Publisher : Routledge
ISBN 13 : 135144459X
Total Pages : 477 pages
Book Rating : 4.3/5 (514 download)
Download or read book Glycerine written by Eric Jungermann and published by Routledge. This book was released on 2018-05-02 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively covers the chemical and physical properties and manufacturing and handling procedures of glycerine and the use of this material in cosmetic and personal care products and in other industrial areas such as testing laboratories and manufacturing and marketing sectors.
