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Clinical Pharmacology In Space
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Book Synopsis Space Pharmacology by : Virginia E. Wotring
Download or read book Space Pharmacology written by Virginia E. Wotring and published by Springer Science & Business Media. This book was released on 2012-03-18 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Space Pharmacology” is a review of the current knowledge regarding the use of pharmaceuticals during spaceflights. It is a comprehensive review of the literature, addressing each area of pharmacokinetics and each major physiological system in turn. Every section begins with a topic overview, and is followed by a discussion of published data from spaceflight, and from ground experiments meant to model the spaceflight situation. Includes a discussion looking forward to the new medical challenges we are likely to face on longer duration exploration missions. This book is a snapshot of our current knowledge that also highlights areas of unknown.
Download or read book Clinical pharmacology in space written by and published by . This book was released on 1991 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clinical Pharmacology in Space written by and published by . This book was released on 1991 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Clinical Pharmacology in Space by : American College of Clinical Pharmacology
Download or read book Clinical Pharmacology in Space written by American College of Clinical Pharmacology and published by . This book was released on 1991 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Space Physiology and Medicine by : Arnauld E. Nicogossian
Download or read book Space Physiology and Medicine written by Arnauld E. Nicogossian and published by . This book was released on 1982 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: 2009 life science book award from IAA.
Book Synopsis Handbook of Space Pharmaceuticals by : Yashwant V. Pathak
Download or read book Handbook of Space Pharmaceuticals written by Yashwant V. Pathak and published by Springer. This book was released on 2022-04-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook, directed at medical professionals and students who are involved in developing the space industry or are academicians doing research in this area, covers current pharmaceutical knowledge about the difference in medication efficacy in space versus on Earth and includes trial results and best practices for the space research and travel industry. The well-known contributors come from an interdisciplinary background and address all aspects of the subject, from the physiological impact of spaceflight to the effects of radiation. As the commercial space industry expands its operations in industry and tourism, the field of space pharmaceuticals is growing commensurately. Existing pharmacological research from space is thoroughly covered in this book, and Earth applications are also described. Potential pharmacological solutions are posed along with the known challenges and examples from existing studies, which are detailed at length. This major reference work is a comprehensive and important medical resource for all space industry players.
Book Synopsis Safe Passage by : Institute of Medicine
Download or read book Safe Passage written by Institute of Medicine and published by National Academies Press. This book was released on 2001-11-20 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Safe Passage: Astronaut Care for Exploration Missions sets forth a vision for space medicine as it applies to deep space voyage. As space missions increase in duration from months to years and extend well beyond Earth's orbit, so will the attendant risks of working in these extreme and isolated environmental conditions. Hazards to astronaut health range from greater radiation exposure and loss of bone and muscle density to intensified psychological stress from living with others in a confined space. Going beyond the body of biomedical research, the report examines existing space medicine clinical and behavioral research and health care data and the policies attendant to them. It describes why not enough is known today about the dangers of prolonged travel to enable humans to venture into deep space in a safe and sane manner. The report makes a number of recommendations concerning NASA's structure for clinical and behavioral research, on the need for a comprehensive astronaut health care system and on an approach to communicating health and safety risks to astronauts, their families, and the public.
Book Synopsis Space Physiology and Medicine by : Arnauld E. Nicogossian
Download or read book Space Physiology and Medicine written by Arnauld E. Nicogossian and published by Lippincott Williams & Wilkins. This book was released on 1994 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nicogossian, Arnauld E., Investigator, NASA Center: HQS; Huntoon, Carolyn Leach, Investigator, NASA Center: JSC; Pool, Sam L., Investigator, NASA Center: JSC.
Book Synopsis Space Physiology and Medicine by : Arnauld E. Nicogossian
Download or read book Space Physiology and Medicine written by Arnauld E. Nicogossian and published by Springer. This book was released on 2016-12-13 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: As space medicine evolved from the late 1950s onward, the need arose for a ready reference for students and practitioners on the basic concepts of this new specialty. Through three editions edited by leaders in the development of space medicine, this classic text has met the need. This fourth edition of Space Physiology and Medicine provides succinct, evidence-based summaries of the current knowledge base in space medicine and serves as a source of information on the space environment, responses, and practices. Additionally, there is extensive online material available for each chapter, featuring overviews and self-study questions.
Author :National Aeronautics and Space Administration (NASA) Publisher :Createspace Independent Publishing Platform ISBN 13 :9781720403364 Total Pages :30 pages Book Rating :4.4/5 (33 download)
Book Synopsis Bioavailability and Pharmacodynamics of Promethazine on Long Duration Missions to the International Space Station by : National Aeronautics and Space Administration (NASA)
Download or read book Bioavailability and Pharmacodynamics of Promethazine on Long Duration Missions to the International Space Station written by National Aeronautics and Space Administration (NASA) and published by Createspace Independent Publishing Platform. This book was released on 2018-05-29 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: Space motion sickness (SMS) is often treated in space with promethazine (PMZ). Common side effects of PMZ administration (50 mg intramuscular) on the ground are drowsiness and impaired cognitive performance. Anecdotal reports indicate that these effects are absent or less pronounced in space. This suggests that the availability of PMZ to the body (bioavailability) and/or the response of the body to PMZ (pharmacodynamics) may change during space flight. Opportunities for clinical research in space are limited. The study described here is our response to a NASA Research Announcement for proposals for flight-based research needed to improve, or answer specific questions about, diagnosis and therapy during space flight, and post-flight rehabilitation. We propose here to evaluate noninvasive methods for determining the bioavailability and pharmacodynamics of PMZ. The specific objectives of the proposed research are to 1) compare pharmacokinetic and pharmacodynamic parameters of PMZ, estimated from saliva and plasma levels after administration of PMZ, 2) estimate the relative bioavailability of the three dosage forms of PMZ that are often administered to control motion sickness symptoms in space, and 3) establish the dose-response relationship of PMZ. We will estimate the bioavailability of an intramuscular injection (IM), oral tablet, and rectal suppository of PMZ in noma1 subjects during ambulatory and antiorthostatic bed rest (ABR) conditions using novel stable isotope techniques. We will compare and contrast the bioavailability of PMZ during normal and microgravity conditions to examine changes in drug absorption and bioavailability during microgravit. Results of this study will validate methods for an approved in-flight investigation with this medication awaiting an opportunity for manifestation..Putcha, Lakshmi and Boyd, Jason L. and Cintron, Nitza and Berens, Kurt L.Johnson Space CenterAEROSPACE MEDICINE; DOSAGE; DRUGS; MOTION SICKNESS; SPACE ADAPTATION SYNDROME; I
Book Synopsis Human Health and Performance Risks of Space Exploration Missions by : Jancy C. McPhee
Download or read book Human Health and Performance Risks of Space Exploration Missions written by Jancy C. McPhee and published by U. S. National Aeronautics & Space Administration. This book was released on 2009 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Space Clinical Medicine by : D.E. Busby
Download or read book Space Clinical Medicine written by D.E. Busby and published by Springer. This book was released on 2011-10-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many real and potential hazards will face astronauts* during operations in space. Some of these hazards might be of little medical significance; others might produce serious medical problems. This book is an initial attempt to describe the characteristics and suggest the management of possible medical problems which might arise from hazards of space operations. Attention is not given here to the so-called 'naturally occurring' diseases. Writing is oriented to future interplanetary missions during which, due primarily to the time required to return to earth, the diagnosis and definitive or interim treatment of medical problems will have to be carried out in space. It is therefore assumed that suitable diagnostic and treatment facilities and medically trained personnel will be available on advanced spacecraft, in which large, multidisciplined crews will be living in a comfortable, 'shirt-sleeves' environment. To lay the groundwork of Space Clinical Medicine, a field in which very little has been written and essentially no experience gained to date, it was found necessary to consider clinical manifestations, diagnosis, and treatment of possible medical problems in space. Wherever necessary, various hazards of space operations are defined and analysed in order to determine their possible medical effects. The patho physiologic characteristics of medical problems are discussed, frequently in detail, to provide the rationale for their prevention and treatment.
Book Synopsis Principles of Clinical Pharmacology by : Arthur J. Atkinson Jr.
Download or read book Principles of Clinical Pharmacology written by Arthur J. Atkinson Jr. and published by Elsevier. This book was released on 2011-04-28 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists. - Unique breadth of coverage ranging from drug discovery and development to individualization and quality assessment of drug therapy - Unusual cohesive of presentation that stems from author participation in an ongoing popular NIH course - Instructive linkage of pharmacokinetic theory and applications with provision of sample problems for self-study - Wide-ranging perspective of authors drawn from the ranks of Federal agencies, academia and the pharmaceutical industry - Expanded coverage of pharmacogenetics - Expanded coverage of drug transporters and their role in interactions - Inclusion of new material on enzyme induction mechanisms in chapters on drug metabolism and drug interactions - A new chapter on drug discovery that focuses on oncologic agents - Inclusion of therapeutic antibodies in chapter on biotechnology products
Book Synopsis Introduction to Clinical Pharmacology - E-Book by : Constance G Visovsky
Download or read book Introduction to Clinical Pharmacology - E-Book written by Constance G Visovsky and published by Elsevier Health Sciences. This book was released on 2018-03-19 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: - NEW! Chapter on Eye and Ear Medications focuses on important glaucoma treatments. - NEW! Dosage ranges added to drug tables reinforce safe medication administration - NEW! Top tips for safety and clinical care provide you with advice from practicing nurses in applicable situations. - NEW! Expanded content on cultural considerations help you think about ethnic differences that may relate to each drug class. - NEW! Drug and IV calculation questions test your knowledge of dosages and calculations.
Book Synopsis Recapturing a Future for Space Exploration by : National Research Council
Download or read book Recapturing a Future for Space Exploration written by National Research Council and published by National Academies Press. This book was released on 2012-01-30 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than four decades have passed since a human first set foot on the Moon. Great strides have been made in our understanding of what is required to support an enduring human presence in space, as evidenced by progressively more advanced orbiting human outposts, culminating in the current International Space Station (ISS). However, of the more than 500 humans who have so far ventured into space, most have gone only as far as near-Earth orbit, and none have traveled beyond the orbit of the Moon. Achieving humans' further progress into the solar system had proved far more difficult than imagined in the heady days of the Apollo missions, but the potential rewards remain substantial. During its more than 50-year history, NASA's success in human space exploration has depended on the agency's ability to effectively address a wide range of biomedical, engineering, physical science, and related obstacles-an achievement made possible by NASA's strong and productive commitments to life and physical sciences research for human space exploration, and by its use of human space exploration infrastructures for scientific discovery. The Committee for the Decadal Survey of Biological and Physical Sciences acknowledges the many achievements of NASA, which are all the more remarkable given budgetary challenges and changing directions within the agency. In the past decade, however, a consequence of those challenges has been a life and physical sciences research program that was dramatically reduced in both scale and scope, with the result that the agency is poorly positioned to take full advantage of the scientific opportunities offered by the now fully equipped and staffed ISS laboratory, or to effectively pursue the scientific research needed to support the development of advanced human exploration capabilities. Although its review has left it deeply concerned about the current state of NASA's life and physical sciences research, the Committee for the Decadal Survey on Biological and Physical Sciences in Space is nevertheless convinced that a focused science and engineering program can achieve successes that will bring the space community, the U.S. public, and policymakers to an understanding that we are ready for the next significant phase of human space exploration. The goal of this report is to lay out steps and develop a forward-looking portfolio of research that will provide the basis for recapturing the excitement and value of human spaceflight-thereby enabling the U.S. space program to deliver on new exploration initiatives that serve the nation, excite the public, and place the United States again at the forefront of space exploration for the global good.
Book Synopsis Space Science in the Twenty-first Century by :
Download or read book Space Science in the Twenty-first Century written by and published by . This book was released on 1988 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bad Pharma written by Ben Goldacre and published by Macmillan. This book was released on 2014-04 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published in 2012, revised edition published in 2013, by Fourth Estate, Great Britain; Published in the United States in 2012, revised edition also, by Faber and Faber, Inc.
