Cirrhosis Hyperammonemia And Hepatic Encephalopathy

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Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy

Author : Santiago Grisolía
Publisher : Springer Science & Business Media
ISBN 13 : 1461524849
Total Pages : 150 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy by : Santiago Grisolía

Download or read book Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy written by Santiago Grisolía and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the papers presented in the International Summer Course on "Cirrhosis, Hyperammonemia and Hepatic Encephalopathy," which was one of the prestigious Summer Course, of the Complutense University of Madrid held in EI Escorial, Spain, during August 10-14, 1992. Liver cirrhosis is one of the main causes of death in western countries. In addition there is a series of liver dysfunctions including fulminant hepatic failure, Reye's syndrome and congenital defects of urea cycle enzymes that could lead to hepatic encephalopathy, coma and death. As a consequence of impaired liver function, the ability to detoxify ammonia by its incorporation into urea is diminshed, resulting in increased ammonia levels in blood and brain. Hyperammonemia is considered one of the main factors in the mediation of hepatic encephalopathy and the classical clinical treatments are directed towards reducing blood ammonia levels. A part of the book is therefore devoted to the study of certain aspects of ammonia metabolism such as the regulation of the urea cycle, the main mechanism of ammonia detoxification in mammals, which is located mainly in the liver. The metabolism of ammonia in other tissues, including brain, is also presented, as well as the effects of hyperammonemia on brain metabolism and function and on brain microtubules. The control of cerebral protein breakdown is reviewed. The classical and some recently proposed clinical treatments as well as nutritional considerations in the management of patients with liver failure are also discussed.

Hepatic Encephalopathy, Hyperammonemia, and Ammonia Toxicity

Author : Vicente Felipo
Publisher : Springer Science & Business Media
ISBN 13 : 1461519896
Total Pages : 215 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Hepatic Encephalopathy, Hyperammonemia, and Ammonia Toxicity by : Vicente Felipo

Download or read book Hepatic Encephalopathy, Hyperammonemia, and Ammonia Toxicity written by Vicente Felipo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the papers presented at the International Symposium on "Cirrhosis, Hyperammonemia and Hepatic Encephalopathy", held in Valencia, Spain, January 24th-27th, 1994. Liver cirrhosis and other hepatic dysfunctions such as fulminant hepatic failure and congenital defects of urea cycle enzymes can lead to hepatic encephalopathy, coma and death. Hepatic encephalopathy is one of the main causes of death in western countries. The ability to detoxify ammonia by its incorporation into urea is diminished by impaired liver function, resulting in increased ammonia levels in blood and brain. Hyperammonemia is considered one of the main factors in the mediation of hepatic encephalopathy and the classical clinical treatments are directed towards reducing blood ammonia levels. However, the molecular bases of the pathogenesis of hepatic encephalopathy and the role of hyperammonemia in this process remain unclear and several hypotheses have been proposed. To clarify the mechanisms involved in hepatic encephalopathy and hyperammonemia suitable animal models are necessary. The animal models available and the ideal features of an animal model are presented in the initial part of the book.

Advances in Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy

Author : Vicente Felipo
Publisher : Springer Science & Business Media
ISBN 13 : 1461559456
Total Pages : 280 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Advances in Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy by : Vicente Felipo

Download or read book Advances in Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy written by Vicente Felipo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of an international symposiu, held in Valencia, Spain, December 2-4, 1996

Hepatic Encephalopathy

Author : Kevin D. Mullen
Publisher : Springer Science & Business Media
ISBN 13 : 1617798363
Total Pages : 251 pages
Book Rating : 4.6/5 (177 download)

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Book Synopsis Hepatic Encephalopathy by : Kevin D. Mullen

Download or read book Hepatic Encephalopathy written by Kevin D. Mullen and published by Springer Science & Business Media. This book was released on 2012-05-30 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because of the increasing burden of hepatitis C and fatty liver disease, there is an explosion in the prevalence of chronic liver failure and hence its complications. The onset of Hepatic Encephalopathy (HE) in these patients has a significant impact on the quality of life, morbidity and mortality. Unfortunately, the approach observed by most clinicians to this complex disorder is minimalistic. This book provides a comprehensive review on pathophysiology and clinically important aspects in HE. Topics in basic physiology, nitrogen metabolism, new insights into pathogenesis and brain edema are covered in great detail. The authors have made a special effort by simplifying the complex aspects of pathogenesis and diagnosis so that it can be easily understood and applied clinically. This volume also focuses on recent developments regarding diagnoses of subtle forms of HE, also known as minimal or covert HE as well as on new treatments. Hepatic Encephalopathy will be of great value to gastroenterologists, hepatologists, pathologists, medical residents, fellows, internists and general practitioners who treat patients with hepatic encephalopathy.

Hepatic Encephalopathy

Author : Roger F. Butterworth
Publisher : Springer Science & Business Media
ISBN 13 : 1461245060
Total Pages : 614 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Hepatic Encephalopathy by : Roger F. Butterworth

Download or read book Hepatic Encephalopathy written by Roger F. Butterworth and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Encephalopathy and Nitrogen Metabolism in Liver Failure

Author : E. Anthony Jones
Publisher : Springer Science & Business Media
ISBN 13 : 9401001596
Total Pages : 454 pages
Book Rating : 4.4/5 (1 download)

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Book Synopsis Encephalopathy and Nitrogen Metabolism in Liver Failure by : E. Anthony Jones

Download or read book Encephalopathy and Nitrogen Metabolism in Liver Failure written by E. Anthony Jones and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encephalopathy and Nitrogen Metabolism in Liver Failure contains research reports and state-of-the-art reviews that were presented at the 11th International Symposium on Hepatic Encephalopathy and Nitrogen Metabolism in relation to liver disease, that was held in Amsterdam, The Netherlands from 30 May to 1 June, 2002. Themes covered include the metabolism of ammonia and amino acids in relation to liver disease, the assessment of hepatic encephalopathy (HE), minimal HE, animal models of HE, neuropsychiatric dysfunction in patients with chronic liver disease, the pathogenesis of HE, the astrocyte in liver disease, acute liver failure and cerebral edema, treatment of HE and artificial liver support systems. This volume provides an indispensable source of important new research findings and ideas for clinicians and biomedical scientists working in the field of HE and nitrogen metabolism in relation to liver disease.

Oxidative Stress

Author : Helmut Sies
Publisher : Academic Press
ISBN 13 : 0128196963
Total Pages : 876 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Oxidative Stress by : Helmut Sies

Download or read book Oxidative Stress written by Helmut Sies and published by Academic Press. This book was released on 2019-11-07 with total page 876 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative Stress: Eustress and Distress presents current knowledge on oxidative stress within the framework of redox biology and translational medicine. It describes eustress and distress in molecular terms and with novel imaging and chemogenetic approaches in four sections: A conceptual framework for studying oxidative stress. Processes and oxidative stress responses. Signaling in major enzyme systems (oxidative eustress), and damaging modification of biomolecules (oxidative distress). The exposome addresses lifelong exposure and impact on health, nutrient sensing, exercise and environmental pollution. Health and disease processes, including ischemia-reperfusion injury, developmental and psychological disorders, hepatic encephalopathy, skeletal muscle disorders, pulmonary disease, gut disease, organ fibrosis, and cancer. Oxidative Stress: Eustress and Distress is an informative resource useful for active researchers and students in biochemistry, molecular biology, medicinal chemistry, pharmaceutical science, nutrition, exercise physiology, analytical chemistry, cell biology, pharmacology, clinical medicine, and environmental science. Characterizes oxidative stress within the framework of redox biology, redox signaling, and medicine. Empowers researchers and students to quantify specific reactants noninvasively, identify redox biomarkers, and advance translational studies. Features contributions from international leaders in oxidative stress and redox biology research.

Cirrhosis, Hepatic Encephalopathy, and Ammonium Toxicity

Author : Santiago Grisolía
Publisher : Springer Science & Business Media
ISBN 13 : 1468458264
Total Pages : 277 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Cirrhosis, Hepatic Encephalopathy, and Ammonium Toxicity by : Santiago Grisolía

Download or read book Cirrhosis, Hepatic Encephalopathy, and Ammonium Toxicity written by Santiago Grisolía and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of an international symposium held in Valencia, Spain, November 27--29, 1989

Liver Disease and Surgery

Author : Georgios Tsoulfas
Publisher : BoD – Books on Demand
ISBN 13 : 1789850657
Total Pages : 250 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Liver Disease and Surgery by : Georgios Tsoulfas

Download or read book Liver Disease and Surgery written by Georgios Tsoulfas and published by BoD – Books on Demand. This book was released on 2019-11-27 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this book is to present a review of the different categories of liver disease, as well as address the role of surgery in managing these complex diseases. The book includes chapters written by international experts on the most current indications and guidelines regarding the diagnoses and management of liver diseases, as well as a variety of technical elements involved with the surgical procedures. Different surgical techniques involved in performing a hepatectomy will be discussed, including various instruments used, as well as the effect of modern technology as evidenced by novel procedures. An important focus of the book has been identifying the proper place of all these hepatectomy methods in the armamentarium of the experienced hepatobiliary surgeon, including the role of locoregional treatments such as ablation and embolization as adjuncts. Finally, the role of hepatectomy compared to orthotopic liver transplantation is discussed, so that the reader can have a well-rounded picture of the challenges and opportunities involved. Overall, this book has the potential to serve as an invaluable "tool" for both the hepatologist and the internist, as well as for the hepatic surgeon

Handbook of Liver Disease

Author : Lawrence Samuel Friedman
Publisher :
ISBN 13 : 9780443066337
Total Pages : 481 pages
Book Rating : 4.0/5 (663 download)

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Book Synopsis Handbook of Liver Disease by : Lawrence Samuel Friedman

Download or read book Handbook of Liver Disease written by Lawrence Samuel Friedman and published by . This book was released on 2004 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here's instant access to the symptoms, signs, differential diagnosis, and treatment for the full range of liver disorders. Written by an international 'who's who' of hepatology-and now in full color-this new 2nd Edition provides readers with top-notch, authoritative guidance they can count on! Discusses the hottest topics in the field, such as non-alcoholic steatohepatitis (NASH) and the latest information on liver transplantation. Includes expanded coverage of chronic hepatitis C, most notably the use of combination therapy with peginterferon and ribavirin and improvements in the management of the side effects of antiviral therapy. Offers the most recent therapeutic options for the management of chronic hepatitis B and advances in the understanding of the molecular biology of this virus. Updates the approach to the diagnosis of many liver diseases due to newer tests based on molecular techniques and advances in imaging. Features over 340 full-color illustrations. Uses a redesigned templated, outline format that makes reference a snap. Presents a concise, in-depth clinical summary-in an outline format-of the current practice of hepatology for each major disease entity. Provides a liberal use of tables, algorithms, and figures, rendering complex concepts understandable. Includes key point boxes at the beginning of each chapter, providing at-a-glance access to vital information. Includes alert symbols that highlight information that's critical to patient safety.

Chronic Liver Failure

Author : Pere Ginès
Publisher : Springer Science & Business Media
ISBN 13 : 1607618664
Total Pages : 583 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Chronic Liver Failure by : Pere Ginès

Download or read book Chronic Liver Failure written by Pere Ginès and published by Springer Science & Business Media. This book was released on 2010-11-03 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.

Biomarkers in Inborn Errors of Metabolism

Author : Uttam Garg
Publisher : Elsevier
ISBN 13 : 0128029188
Total Pages : 476 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Biomarkers in Inborn Errors of Metabolism by : Uttam Garg

Download or read book Biomarkers in Inborn Errors of Metabolism written by Uttam Garg and published by Elsevier. This book was released on 2017-06-07 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers of Inborn Errors in Metabolism: Clinical Aspects and Laboratory Determination is structured around the new reality that laboratory testing and biomarkers are an integral part in the diagnosis and treatment of inherited metabolic diseases. The book covers currently used biomarkers as well as markers that are in development. Because biomarkers used in the initial diagnosis of disease may be different than the follow-up markers, the book also covers biomarkers used in both the prognosis and treatment of inherited metabolic disorders. With the introduction of expanded new-born screening for inborn metabolic diseases, an increasing numbers of laboratories are involved in follow-up confirmatory testing. The book provides guidance on laboratory test selection and interpreting results in patients with suspected inherited metabolic diseases. The book provides comprehensive guidance on patient diagnosis and follow-up through its illustrative material on metabolic pathways, genetics and pathogenesis, treatment and prognosis of inherited metabolic diseases, along with essential information on clinical presentation. Each chapter is organized with a uniform, easy-to-follow format: a brief description of the disorder and pathway; a description of treatment; biomarkers for diagnosis; biomarkers followed for treatment efficacy; biomarkers followed for disease progression; confounding conditions that can either: affect biomarker expression or mimic IEMs; other biomarkers: less established, future. Provides comprehensive information on the tests/biomarkers selection in newborn screening and follow-up of newborn screens Categorizes biomarkers into diagnostic markers, disease follow-up markers, and prognostic biomarkers Covers confounding factors that can alter biomarkers in the absence of inborn errors of metabolism Offers guidance on how to distinguish acquired causes from inborn errors of metabolism

Hepatic Encephalopathy, An Issue of Clinics in Liver Disease

Author : Vinod Rustgi
Publisher : Elsevier Health Sciences
ISBN 13 : 0323683673
Total Pages : 185 pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Hepatic Encephalopathy, An Issue of Clinics in Liver Disease by : Vinod Rustgi

Download or read book Hepatic Encephalopathy, An Issue of Clinics in Liver Disease written by Vinod Rustgi and published by Elsevier Health Sciences. This book was released on 2020-05-11 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: In collaboration with Consulting Editor, Dr. Norman Gitlin, Dr. Vinod Rustgi has put together topics that provide a current clinical update on the treatment and management of patients with Hepatic Encephalopathy (HE). Experts in the field have contributetd clinical review articles on the following topics: Definition, Prevalence, and Epidemiology of HE; Pathophysiology of HE; Clinical Manifestations of HE; Laboratory Abnormalities of HE; Minimal or Subclinical HE; Prognosis of Prognosis of HE; Pharmacological Management of HE; Non-pharmacological Management of HE; Cost Burden of HE; Long-term management of HE: Modern Measures to Prevent Re-admission; Social Impact of HE; and Novel Therapies for HE. Readers will come away with the information they need to improve outcomes in patients with HE.

Advances in Hepatic Encephalopathy and Urea Cycle Diseases

Author : Gunter Kleinberger
Publisher : S. Karger AG (Switzerland)
ISBN 13 :
Total Pages : 792 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Advances in Hepatic Encephalopathy and Urea Cycle Diseases by : Gunter Kleinberger

Download or read book Advances in Hepatic Encephalopathy and Urea Cycle Diseases written by Gunter Kleinberger and published by S. Karger AG (Switzerland). This book was released on 1984 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Hepatic Encephalopathy

Author : Frederick Steigmann
Publisher :
ISBN 13 :
Total Pages : 224 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Hepatic Encephalopathy by : Frederick Steigmann

Download or read book Hepatic Encephalopathy written by Frederick Steigmann and published by . This book was released on 1971 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Liver Disease in Children

Author : Frederick J. Suchy
Publisher : Cambridge University Press
ISBN 13 : 1108911374
Total Pages : 875 pages
Book Rating : 4.1/5 (89 download)

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Book Synopsis Liver Disease in Children by : Frederick J. Suchy

Download or read book Liver Disease in Children written by Frederick J. Suchy and published by Cambridge University Press. This book was released on 2021-03-18 with total page 875 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver disease in children is increasing in prevalence, placing a huge burden on healthcare systems and often requiring long-term management. Offering an integrative approach to the science and clinical practice of pediatric hepatology, this is the definitive reference text for improved diagnosis and treatment strategies. In the new edition of this authoritative text, chapters have been thoroughly revised in line with major advances in the field, such as recognizing the increased frequency of fatty liver disease, and how genetic testing has the potential to establish earlier diagnoses for a variety of diseases. Disorders covered include cholestasis, metabolic disorders and hepatitis, with their presentation across the spectrum of infancy, childhood and adolescence discussed. The indications and surgical aspects of liver transplant are explained and post-transplant care is described in detail. This is a valuable resource for pediatricians, hepatologists, gastroenterologists and all clinicians involved in the care of children with liver diseases.

Bile Acids and Their Receptors

Author : Stefano Fiorucci
Publisher : Springer Nature
ISBN 13 : 3030220052
Total Pages : 378 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Bile Acids and Their Receptors by : Stefano Fiorucci

Download or read book Bile Acids and Their Receptors written by Stefano Fiorucci and published by Springer Nature. This book was released on 2019-09-03 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focusses on the latest results related to the field of bile acids as signaling molecules and describes how these receptors have become a major pharmacological target. It covers all major areas of research in this field, from genetics, chemistry, in silico modeling, molecular biology to clinical applications, offering a cross-country view of the functional role of bile acids as signaling molecules, virtually acting on all major areas of metabolism. While FXR and GPBAR1 are essential bile acid sensors that integrate the de novo bile acid synthesis with intestinal microbiota and liver metabolism, in a broader sense, BARs play a pathogenic role in the development of common human alignments including liver, intestinal and metabolic disorders, such as steatosis (NAFLD) and steato-hepatitis (NASH), diabetes, obesity and atherosclerosis.