Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic

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Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110526980
Total Pages : 640 pages
Book Rating : 4.1/5 (15 download)

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Book Synopsis Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic by : Peggy L. Carver

Download or read book Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic written by Peggy L. Carver and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-01-14 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 19, entitled Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic of the series Metal Ions in Life Sciences centers on the role of metal ions in clinical medicine. Metal ions are tightly regulated in human health: while essential to life, they can be toxic as well. Following an introductory chapter briefly discussing several important metal-related drugs and diseases and a chapter about drug development, the focus is fi rst on iron: its essentiality for pathogens and humans as well as its toxicity. Chelation therapy is addressed in the context of thalassemia, its relationship to neurodegenerative diseases and also the risks connected with iron administration are pointed out. A subject of intense debate is the essentiality of chromium and vanadium. For example, chromium(III) compounds are taken as a nutritional supplement by athletes and bodybuilders; in contrast, chromate, Cr(VI), is toxic and a carcinogen for humans. The benefi cial and toxic effects of manganese, cobalt, and copper on humans are discussed. The need for antiparasitic agents is emphasized as well as the clinical aspects of metal-containing antidotes for cyanide poisoning. In addition to the essential and possibly essential ones, also other metal ions play important roles in human health, causing harm (like the metalloid arsenic, lead or cadmium) or being used in diagnosis or treatment of human diseases, like gadolinium, gallium, lithium, gold, silver or platinum. The impact of this vibrant research area on metals in the clinic is provided in 14 stimulating chapters, written by internationally recognized experts from the Americas, Europe and China, and is manifested by approximately 2000 references, and about 90 illustrations and tables. Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic is an essential resource for scientists working in the wide range from pharmacology, enzymology, material sciences, analytical, organic, and inorganic biochemistry all the way through to medicine ... not forgetting that it also provides excellent information for teaching.

Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc

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Author :
Publisher : National Academies Press
ISBN 13 : 9780309072793
Total Pages : 804 pages
Book Rating : 4.0/5 (727 download)

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Book Synopsis Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc by : Institute of Medicine

Download or read book Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc written by Institute of Medicine and published by National Academies Press. This book was released on 2002-07-19 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the newest release in the authoritative series issued by the National Academy of Sciences on dietary reference intakes (DRIs). This series provides recommended intakes, such as Recommended Dietary Allowances (RDAs), for use in planning nutritionally adequate diets for individuals based on age and gender. In addition, a new reference intake, the Tolerable Upper Intake Level (UL), has also been established to assist an individual in knowing how much is "too much" of a nutrient. Based on the Institute of Medicine's review of the scientific literature regarding dietary micronutrients, recommendations have been formulated regarding vitamins A and K, iron, iodine, chromium, copper, manganese, molybdenum, zinc, and other potentially beneficial trace elements such as boron to determine the roles, if any, they play in health. The book also: Reviews selected components of food that may influence the bioavailability of these compounds. Develops estimates of dietary intake of these compounds that are compatible with good nutrition throughout the life span and that may decrease risk of chronic disease where data indicate they play a role. Determines Tolerable Upper Intake levels for each nutrient reviewed where adequate scientific data are available in specific population subgroups. Identifies research needed to improve knowledge of the role of these micronutrients in human health. This book will be important to professionals in nutrition research and education.

Interrelations between Essential Metal Ions and Human Diseases

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9400775008
Total Pages : 603 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Interrelations between Essential Metal Ions and Human Diseases by : Astrid Sigel

Download or read book Interrelations between Essential Metal Ions and Human Diseases written by Astrid Sigel and published by Springer Science & Business Media. This book was released on 2014-01-27 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: MILS-13 provides an up-to-date review on the relationships between essential metals and human diseases, covering 13 metals and 3 metalloids: The bulk metals sodium, potassium, magnesium, and calcium, plus the trace elements manganese, iron, cobalt, copper, zinc, molybdenum, and selenium, all of which are essential for life. Also covered are chromium, vanadium, nickel, silicon, and arsenic, which have been proposed as being essential for humans in the 2nd half of the last century. However, if at all, they are needed only in ultra-trace amounts, and because of their prevalence in the environment, it has been difficult to prove whether or not they are required. In any case, all these elements are toxic in higher concentrations and therefore, transport and cellular concentrations of at least the essential ones, are tightly controlled; hence, their homeostasis and role for life, including deficiency or overload, and their links to illnesses, including cancer and neurological disorders, are thoroughly discussed. Indeed, it is an old wisdom that metals are indispensable for life. Therefore, Volume 13 provides in an authoritative and timely manner in 16 stimulating chapters, written by 29 internationally recognized experts from 7 nations, and supported by more than 2750 references, and over 20 tables and 80 illustrations, many in color, a most up-to-date view on the vibrant research area of the Interrelations between Essential Metal Ions and Human Diseases.

The Bioinorganic Chemistry of Chromium

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Publisher : John Wiley & Sons
ISBN 13 : 1118458850
Total Pages : 259 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis The Bioinorganic Chemistry of Chromium by : John B. Vincent

Download or read book The Bioinorganic Chemistry of Chromium written by John B. Vincent and published by John Wiley & Sons. This book was released on 2012-10-04 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromium exists in nature as complexes of two stable oxidation states – trivalent chromium(III) and hexavalent chromium(VI). Although trivalent chromium is required in trace amounts for sugar and lipid metabolism in humans and its deficiency may cause a disease called chromium deficiency; hexavalent chromium is toxic and carcinogenic. As chromium compounds were used in dyes and paints and the tanning of leather, these compounds are often found in soil and groundwater at abandoned industrial sites, now needing environmental cleanup and remediation. The Bioinorganic Chemistry of Chromium: From Biochemistry to Environmental Toxicology takes a critical look at what the biochemical data indicate about chromium's role in the body and the biological mechanisms of its toxicology. Topics covered include: What do we know about the biochemical roles and mechanisms of chromium? Is chromium an essential element in the mammalian diet? Is chromium(III) effective as a nutraceutical, a therapeutic agent, and as a supplement in animal feed? What is the biochemistry behind the toxicology of chromium(III) and chromium(VI):the mechanisms of metabolism, genetic and epigenetic effects, and disruption of cell signalling? What are the current chromium(VI) policies and positions from regulatory agencies? The Bioinorganic Chemistry of Chromium: From Biochemistry to Environmental Toxicology is an important contribution to the bioinorganic and trace element biochemical fields which will find a place on the bookshelves of bioinorganic chemists, biochemists, inorganic chemists, toxicologists, nutritionists and regulatory affairs professionals.

Lifting Your Depression

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Publisher : Basic Health Publications, Inc.
ISBN 13 : 9781591202455
Total Pages : 228 pages
Book Rating : 4.2/5 (24 download)

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Book Synopsis Lifting Your Depression by : Malcolm N. McLeod

Download or read book Lifting Your Depression written by Malcolm N. McLeod and published by Basic Health Publications, Inc.. This book was released on 2009 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: If you have picked up this book, chances are that you or someone you care about struggles with depression. In addition to feeling depressed, or "down," or "blue," ask yourself the following questions: Do you crave sweets and other carbohydrates, or tend to gain weight? Are you exhausted or tired for no obvious reason? Do you have trouble concentrating or thinking clearly? Are your feelings easily hurt by rejection from others? If you answered "yes" to even one of these questions, you may be suffering from a particular type of depression that does not respond well to most antidepressant drugs. Take heart. There is hope, thanks to a major medical discovery made by longtime psychiatrist Malcolm McLeod of a connection between depression, resistance of the body to insulin, faulty glucose metabolism, and how the trace mineral chromium can dramatically lift depression. Moreover, chromium is a natural treatment that is safe, effective and free of unwanted side effects. Book jacket.

Dietary Supplements

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Publisher : National Academies Press
ISBN 13 : 0309091101
Total Pages : 527 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Dietary Supplements by : National Research Council

Download or read book Dietary Supplements written by National Research Council and published by National Academies Press. This book was released on 2005-01-03 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growing consumer interest in health and fitness has expanded the market for a wide range of products, from yoga mats to the multiple dietary supplements now on the market. Supplements are popular, but are they safe? Many dietary supplements are probably safe when used as recommended. However, since 1994 when Congress decided that they should be regulated as if they were foods, they are assumed to be safe unless the Food and Drug Administration can demonstrate that they pose a significant risk to the consumer. But there are many types of products that qualify as dietary supplements, and the distinctions can become muddled and vague. Manufacturers are not legally required to provide specific information about safety before marketing their products. And the sales of supplements have been steadily increasingâ€"all together, the various types now bring in almost $16 billion per year. Given these confounding factors, what kind of information can the Food and Drug Administration use to effectively regulate dietary supplements? This book provides a framework for evaluating dietary supplement safety and protecting the health of consumers.

The Vitamin Cure for Alcoholism

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Publisher : Basic Health Publications, Inc.
ISBN 13 : 9781591202547
Total Pages : 148 pages
Book Rating : 4.2/5 (25 download)

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Book Synopsis The Vitamin Cure for Alcoholism by : Abram Hoffer

Download or read book The Vitamin Cure for Alcoholism written by Abram Hoffer and published by Basic Health Publications, Inc.. This book was released on 2009 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcoholics suffer from a nutrient deficiency, especially vitamin B3. This work outlines the nutritional factors proven successful in treating alcoholism. It can help those who suffer from alcohol addiction, their friends and loved-ones, and those in the relevant helping professions.

The Fat Flush Plan

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Publisher : McGraw Hill Professional
ISBN 13 : 0071504435
Total Pages : 279 pages
Book Rating : 4.0/5 (715 download)

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Book Synopsis The Fat Flush Plan by : Ann Louise Gittleman

Download or read book The Fat Flush Plan written by Ann Louise Gittleman and published by McGraw Hill Professional. This book was released on 2001-12-27 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kiss cellulite goodbye! The Fat Flush® Plan melts fat from hips, waist, and thighs in just two weeks and re-shapes your body while detoxifying your system. The Fat Flush Plan is a groundbreaking low carb/detox diet and fitness program. Fat Flush is known as the only diet program that gets rid of bloat, supports the liver, cleans up the lymph, and helps to eliminate the appearance of cellulite – for good. An international best-seller with legions of devoted followers, The Fat Flush Plan has been featured on "The View," as well as in cover articles in Time, Glamour, Self, and many others. It is based upon essential fats (such as flax seed oil and flax seeds), balanced proteins (including eggs, meat, fish, and moderate soy) plus low-glycemic healthy carbs from fat flushing fruits and vegetables. The Plan also features “cleansing” tonics such as unsweetened cranberry juice and water, the “Long Life Cocktail,” and daily hot water and lemon juice as well as a delicious array of fat burning, water regulating, and insulin controlling herbs and spices (think cayenne, mustard, cilantro, parsley, cinnamon, and cloves).

Toxicological Profile for Chromium

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Author :
Publisher : Createspace Independent Publishing Platform
ISBN 13 : 9781495287336
Total Pages : 592 pages
Book Rating : 4.2/5 (873 download)

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Book Synopsis Toxicological Profile for Chromium by : U.s. Department of Health and Human Services

Download or read book Toxicological Profile for Chromium written by U.s. Department of Health and Human Services and published by Createspace Independent Publishing Platform. This book was released on 2014-01-22 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: This toxicological profile is prepared in accordance with guidelines developed by the Agency for Toxic Substances and Disease Registry (ATSDR) and the Environmental Protection Agency (EPA). The original guidelines were published in the Federal Register on April 17, 1987. Each profile will be revised and republished as necessary. The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects information for the toxic substances each profile describes. Each peer-reviewed profile identifies and reviews the key literature that describes a substance's toxicologic properties. Other pertinent literature is also presented but is described in less detail than the key studies. The profile is not intended to be an exhaustive document; however, more comprehensive sources of specialty information are referenced. The profiles focus on health and toxicologic information; therefore, each toxicological profile begins with a public health statement that describes, in nontechnical language, a substance's relevant toxicological properties. Following the public health statement is information concerning levels of significant human exposure and, where known, significant health effects. A health effects summary describes the adequacy of information to determine a substance's health effects. ATSDR identifies data needs that are significant to protection of public health. Each profile: (A) Examines, summarizes, and interprets available toxicologic information and epidemiologic evaluations on a toxic substance to ascertain the levels of significant human exposure for the substance and the associated acute, subacute, and chronic health effects; (B) Determines whether adequate information on the health effects of each substance is available or being developed to determine levels of exposure that present a significant risk to human health of acute, subacute, and chronic health effects; and (C) Where appropriate, identifies toxicologic testing needed to identify the types or levels of exposure that may present significant risk of adverse health effects in humans.

Trace Elements and Minerals in Health and Longevity

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Publisher : Springer
ISBN 13 : 3030037428
Total Pages : 332 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Trace Elements and Minerals in Health and Longevity by : Marco Malavolta

Download or read book Trace Elements and Minerals in Health and Longevity written by Marco Malavolta and published by Springer. This book was released on 2018-11-13 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the role of trace elements in health and longevity, pursuing a biogerontological approach. It offers essential information on the impact of trace elements on molecular and physiological processes of aging, and on their impact on health in connection with aging. The major topics covered in its 11 chapters, each dedicated to a specific trace element or mineral, are: a) Role of the element in species longevity, b) Recommended intake for longevity in animal species and in the elderly, c) Deficiency and age-related disease, d) Excess/toxicity and age-related disease, and e) Interactions with drugs prescribed in the elderly. Clinical, animal and other laboratory models of interest in aging are included, which enable a more in-depth analysis to be made. The respective chapters are a mixture of overviews and more in-depth reviews in which the mechanisms of aging are described from the point of view of their specific interactions with trace elements and minerals.

Mammals and Birds as Bioindicators of Trace Element Contaminations in Terrestrial Environments

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Publisher : Springer
ISBN 13 : 3030001210
Total Pages : 707 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Mammals and Birds as Bioindicators of Trace Element Contaminations in Terrestrial Environments by : Elżbieta Kalisińska

Download or read book Mammals and Birds as Bioindicators of Trace Element Contaminations in Terrestrial Environments written by Elżbieta Kalisińska and published by Springer. This book was released on 2019-03-01 with total page 707 pages. Available in PDF, EPUB and Kindle. Book excerpt: The population explosion that began in the 1960s has been accompanied by a decrease in the quality of the natural environment, e.g. pollution of the air, water and soil with essential and toxic trace elements. Numerous poisonings of people and animals with highly toxic anthropogenic Hg and Cd in the 20th century prompted the creation of the abiotic environment, mainly in developed countries. However, the system is insufficient for long-term exposure to low concentrations of various substances that are mainly ingested through food and water. This problem could be addressed by the monitoring of sentinels – organisms that accumulate trace elements and as such reflect the rate and degree of environmental pollution. Usually these are long-lived vertebrates – herbivorous, omnivorous and carnivorous birds and mammals, especially game species. This book describes the responses of the sentinels most commonly used in ecotoxicological studies to 17 trace elements.

Inorganic Chromium(III) Compounds

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Publisher : World Health Organization
ISBN 13 : 9241530766
Total Pages : 101 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Inorganic Chromium(III) Compounds by : Tiina Santonen

Download or read book Inorganic Chromium(III) Compounds written by Tiina Santonen and published by World Health Organization. This book was released on 2009 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document on inorganic chromium (III) compounds provides summaries of the relevant scientific information concerning the potential effects of these chemicals upon human health and/or the environment. Chemical safety cards on the most common inorganic trivalent chromium compounds are reproduced in this document.

Lipids and Cardiovascular Disease

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Publisher :
ISBN 13 :
Total Pages : 226 pages
Book Rating : 4.:/5 (636 download)

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Book Synopsis Lipids and Cardiovascular Disease by :

Download or read book Lipids and Cardiovascular Disease written by and published by . This book was released on 1990 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Prevention and Treatment of Cardiovascular Disease

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Publisher : Springer Nature
ISBN 13 : 3030781771
Total Pages : 279 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Prevention and Treatment of Cardiovascular Disease by : Michael J. Wilkinson

Download or read book Prevention and Treatment of Cardiovascular Disease written by Michael J. Wilkinson and published by Springer Nature. This book was released on 2021-08-13 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses all aspects of non-pharmacologic approaches to primary and secondary CVD prevention. It highlights the strength of evidence for particular diet styles in CVD prevention, including plant-based diets, the Mediterranean diet, the DASH diet, and low-carbohydrate diets. Chapters present evidence and future directions for diet and nutrition in diseases related to CVD, such as dyslipidemia, cardiometabolic disease (pre-diabetes, the metabolic syndrome, type-2 diabetes mellitus), and obesity. Finally, the book reviews novel and emerging aspects of dietary intervention in CVD prevention, such as dietary approaches to inflammation and the role of the microbiome in CVD. Up-to-date, evidence-based, and clinically oriented, Prevention and Treatment of Cardiovascular Disease: Nutritional and Dietary Approaches is an essential resource for physicians, residents, fellows, and medical students in cardiology, clinical nutrition, family medicine, endocrinology, and lipidology.

Guide to Nutritional Supplements

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Publisher : Academic Press
ISBN 13 : 0123756618
Total Pages : 565 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis Guide to Nutritional Supplements by :

Download or read book Guide to Nutritional Supplements written by and published by Academic Press. This book was released on 2009-09-02 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapidly expanding world of nutrition, functional foods and nutraceuticals, is increasingly complex. This Guide to Nutritional Supplements provides a concise and complete reference to the most common nutritionally significant elements. Including dietary guidelines, intake measurements and other contextual information, this Guide is the ideal reference for nutritionsts and dieticians facing an increasing public awareness of supplements and who many be augmenting their diets with OTC supplements. - Focused on the nutritional values, impacts and interactions of supplements - Provides a science-based approach to determining the appropriate selection and application of supplements for improved diet and nutrition

Trace Elements in Human Health and Disease: Zinc and copper

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Publisher :
ISBN 13 :
Total Pages : 504 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Trace Elements in Human Health and Disease: Zinc and copper by : Donald Oberleas

Download or read book Trace Elements in Human Health and Disease: Zinc and copper written by Donald Oberleas and published by . This book was released on 1976 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Trace Elements in Human Health and Disease is a collection of papers presented at an international symposium on trace elements held in Detroit, Michigan on July 10-12, 1974. The symposium provided a forum for discussing the role of essential and toxic elements in human health and disease. These two volumes bring together a vast amount of information on trace elements zinc and copper, magnesium, selenium, fluoride, cadmium, lead, and mercury. They will be of great value to physicians, nutritionists, and toxicologists. A particularly interesting section relates to the leaching of important trace metals by excess dietary fiber in some developing countries. These books are one of the important monograph series published by the American Nutrition Foundation.

Vitamins and Minerals Demystified

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Publisher : McGraw Hill Professional
ISBN 13 : 007159471X
Total Pages : 363 pages
Book Rating : 4.0/5 (715 download)

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Book Synopsis Vitamins and Minerals Demystified by : Steve Blake

Download or read book Vitamins and Minerals Demystified written by Steve Blake and published by McGraw Hill Professional. This book was released on 2007-10-16 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encapsulating the science behind vitamins and minerals Need to understand how vitamins and minerals work but find dense texts difficult to absorb? Here's your panacea! Vitamins & Minerals Demystified makes it easy to digest information on everything from A to zinc. Written by a holistic health doctor, this essential guide explains the crucial role vitamins and minerals play in nutrition and physiology. You'll find details on the type and amount required for survival and for increased disease resistance. The book outlines the food sources of different vitamins and minerals and covers the benefits and pitfalls of both natural and synthetic vitamins. Featuring end-of-chapter quizzes and a final exam, this book will fortify your knowledge of vitamins and minerals. This fast and easy guide offers: Numerous figures to illustrate key concepts Graphs indicating the foods rich in various vitamins and minerals Charts featuring U.S. Recommended Daily Allowances (USRDAs) Coverage of deficiency-related diseases Quick summaries of each vitamin and mineral reinforce learning Simple enough for a beginner, but challenging enough for an advanced student, Vitamins & Minerals Demystified is the perfect supplement for anyone studying or interested in this important health topic.