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Author :
Publisher : Elsevier
ISBN 13 : 0080858511
Total Pages : 415 pages
Book Rating : 4.0/5 (88 download)
Download or read book Biological Roles and Function of Modification written by and published by Elsevier. This book was released on 1989-12-13 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Roles and Function of Modification
Author :
Publisher : Elsevier
ISBN 13 : 0080858503
Total Pages : 455 pages
Book Rating : 4.0/5 (88 download)
Download or read book Analytical Methods for Major and Modified Nucleosides - HPLC, GC, MS, NMR, UV and FT-IR written by and published by Elsevier. This book was released on 1989-12-13 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analytical Methods for Major and Modified Nucleosides - HPLC, GC, MS, NMR, UV and FT-IR
Author : Henri Grosjean
Publisher : Springer
ISBN 13 : 3540314547
Total Pages : 0 pages
Book Rating : 4.5/5 (43 download)
Download or read book Fine-Tuning of RNA Functions by Modification and Editing written by Henri Grosjean and published by Springer. This book was released on 2005-05-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Naturally occurring RNA always contains numerous biochemically altered nucleotides. They are formed by enzymatic modification of the primary transcripts during the complex RNA maturation process designated RNA modification. A large number of enzymes catalyzing the formation of these modified nucleosides or converting one canonical base into another at the posttranscriptional level have been studied for many years, but only recently have systematic and comparative studies begun. The functions of individual enzymes and/or the modified/edited nucleosides in RNA, however, have remained largely ignored. This book provides advance information on RNA modification, including the associated editing machinery, while offering the reader some perspective on the significance of such modifications in fine-tuning the structure and functions of mature RNA molecules and hence the ability to influence the efficiency and accuracy of genetic expression. Outstanding scientists who are actively working on RNA modification/editing processes have provided up-to-date information on these intriguing cellular processes that have been generated over the course of millions of years in all living organisms. Each review has been written and illustrated for a large audience of readers, not only specialists in the field, but also for advanced students or researchers who want to learn more about recent progress in RNA modification and editing.
Author : Kazuhiko Nakatani
Publisher : Springer
ISBN 13 : 3319271113
Total Pages : 280 pages
Book Rating : 4.3/5 (192 download)
Download or read book Modified Nucleic Acids written by Kazuhiko Nakatani and published by Springer. This book was released on 2016-04-04 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases. Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs. This unique book addresses new developments and is designed for graduate level and professional research purposes.
Author : Jeannine Yon-Kahn
Publisher : Springer Science & Business Media
ISBN 13 : 3642012299
Total Pages : 809 pages
Book Rating : 4.6/5 (42 download)
Download or read book Molecular and Cellular Enzymology written by Jeannine Yon-Kahn and published by Springer Science & Business Media. This book was released on 2011-07-23 with total page 809 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular and Cellular Enzymology addresses not only experienced enzymologists but also students, teachers and academic and industrial researchers who are confronted with enzymological problems during their fundamental or applied research. In this field there is an urgent need for training in order to meet the requirements of both research and industrial endeavours. This book consists of several levels. Practical aspects and elementary explanations are given for the benefit of non-specialists’ and students’ understanding. In order to facilitate the task of students, two typographies have been adopted. The main text corresponds to basic knowledge, whereas text in a smaller font provides more specialised information. Specialists will also find topics more deeply expounded with the principal bibliographic references cited. The bibliography, however, is not exhaustive; the choice includes general books and review articles as well as some specialised articles. In this book, for the first time, the different molecular and cellular aspects of enzymology are presented together. Until now, there has been no book available in which these different aspects are treated in the same volume. In addition, besides the theoretical developments, this book provides a wealth of practical information for experimentalists.
Author : Henri Grosjean
Publisher : CRC Press
ISBN 13 : 1498713157
Total Pages : 682 pages
Book Rating : 4.4/5 (987 download)
Download or read book DNA and RNA Modification Enzymes written by Henri Grosjean and published by CRC Press. This book was released on 2009-06-11 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a timely and comprehensive description of the many facets of DNA and RNA modification-editing processes and to some extent repair mechanisms. Each chapter offers fundamental principles as well as up to date information on recent advances in the field (up to end 2008). They ended by a shortconclusion and future prospect' section and
Author : I. Mikšík
Publisher : Elsevier
ISBN 13 : 0080858686
Total Pages : 1149 pages
Book Rating : 4.0/5 (88 download)
Download or read book Advanced Chromatographic and Electromigration Methods in BioSciences written by I. Mikšík and published by Elsevier. This book was released on 1998-09-28 with total page 1149 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with chromatographic and electrophoretic methods applied for the separation (quantitation and identification) of biologically relevant compounds. It is assumed that the potential reader is familiar with the basics of chromatographic and electromigration methods. Individual separation modes are dealt with to an extent which follows their applicability for biomedical purposes: liquid chromatography and electromigration methods are therefore highlighted.Each chapter is completed with a list of recent literature covering the 1987-1997 period, which can be used for further guidance of the reader in his/her own field. The chapters have been written by specialists in a particular area and with an emphasis on applications to the biomedical field. This implies that theoretical and instrumental aspects are kept to a minimum which allows the reader to understand the text. Considerable attention is paid to method selection, detection and derivatization procedures and troubleshooting. The majority of examples given represent the analyses of typical naturally-occurring mixtures. Adequate attention is paid to the role of the biological matrix and sample pretreatment, and special attention is given to forensic, toxicological and clinical applications. The book is completed with an extensive Index of Compounds Separated.
Author :
Publisher : Elsevier
ISBN 13 : 008085852X
Total Pages : 509 pages
Book Rating : 4.0/5 (88 download)
Download or read book Modified Nucleosides in Cancer and Normal Metabolism - Methods and Applications written by and published by Elsevier. This book was released on 1990-05-02 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modified Nucleosides in Cancer and Normal Metabolism - Methods and Applications
Author : S.C. Moldoveanu
Publisher : Elsevier
ISBN 13 : 0080540708
Total Pages : 949 pages
Book Rating : 4.0/5 (85 download)
Download or read book Sample Preparation in Chromatography written by S.C. Moldoveanu and published by Elsevier. This book was released on 2002-05-08 with total page 949 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sample preparation is an essential step in many analyses. This book approaches the topic of sample preparation in chromatography in a methodical way, viewing it as a logical connection between sample collection and analytical chromatography. Providing a guide for choosing the appropriate sample preparation for a given analysis, this book describes various ways to process the sample, explaining the principle, discussing the advantages and disadvantages, describing the applicability to different types of samples, and showing the fitness to specific chromatographic determinations. The first part of the book contains an overview of sample preparation showing its relation to sample collection and to the core chromatographic analysis. The second part covers procedures that do not use chemical modifications of the analyte and includes methods for sample dissolution, concentration and cleanup designed mainly for modifying the initial matrix of the sample. This part starts with conventional separations such as filtration and distillation and finishes with more advanced techniques such as solid phase extraction and electroseparations. The third part gives a description of the chemical modifications that can be performed on a sample either for fractionation purposes or to improve a specific property of the analyte. This part includes derivatizations, polymer chemical degradations, and pyrolysis.
Author :
Publisher : Elsevier
ISBN 13 : 0080858589
Total Pages : 589 pages
Book Rating : 4.0/5 (88 download)
Download or read book Fundamentals and Techniques written by and published by Elsevier. This book was released on 1991-11-26 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals and Techniques
Author : Jonatha M. Gott
Publisher : Springer Science & Business Media
ISBN 13 : 1592597750
Total Pages : 437 pages
Book Rating : 4.5/5 (925 download)
Download or read book RNA Interference, Editing, and Modification written by Jonatha M. Gott and published by Springer Science & Business Media. This book was released on 2008-02-05 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents a comprehensive collection of cuttingedge methods for elucidating the function of new genes and altering gene expression. These readily reproducible techniques can be used either in transient and stable gene splicing applied to worms, flies, trypanosomes, mammals, and plants, or in studying RNA editing mechanisms in a wide range of organisms, including systems that involve the conversion of one base to another and insertion/deletion editing. Topics of interest include stable and transient RNA interference, gene silencing, RNA editing, bioinformatics, small noncoding RNAs, and RNomics. Special attention is given to methods for the identification and characterization of small RNAs involved in RNA interference or modification. Readily reproducible protocols for discovering new genes or altering gene expression.
Author : V. Betina
Publisher : Elsevier
ISBN 13 : 0080858627
Total Pages : 455 pages
Book Rating : 4.0/5 (88 download)
Download or read book Chromatography of Mycotoxins written by V. Betina and published by Elsevier. This book was released on 1993-05-28 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work comprises two parts, Part A: Techniques and Part B: Applications. In Part A the most important principles of sample preparation, extraction, clean-up, and of established and prospective chromatographic techniques are discussed in relation to mycotoxins. In Part B the most important data, scattered in the literature, on thin-layer, liquid, and gas chromatography of mycotoxins have been compiled. Mycotoxins are mostly arranged according to families, such as aflatoxins, trichothecenes, lactones etc. Chromatography of individual important mycotoxins and multi-mycotoxin chromatographic analyses are also included. Applications are presented in three chapters devoted to thin-layer, liquid, and gas chromatography of mycotoxins.
Author :
Publisher : Elsevier
ISBN 13 : 0080550916
Total Pages : 476 pages
Book Rating : 4.0/5 (85 download)
Download or read book RNA Modification written by and published by Elsevier. This book was released on 2007-09-13 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: The presence of modified nucleotides in cellular RNAs has been known for decades and over 100 distinct RNA modifications have been characterized to date. While the exact role of many of these modifications is still unclear, many are highly conserved across evolution and most contribute to the overall fitness of the organism. In recent years, new methods and bioinformatics approaches have been developed for the dissection of modification pathways and functions. These methods intersect a number of related fields, ranging from RNA processing to comparative genomics and systems biology. In addition, many of the techniques described in this volume have broad applicability, particularly in regards to the isolation, characterization, and reconstitution of ribonucleoprotein complexes, expanding the experimental repertoire available to all RNA researchers.
Author : J. Turková
Publisher : Elsevier
ISBN 13 : 0080858635
Total Pages : 819 pages
Book Rating : 4.0/5 (88 download)
Download or read book Bioaffinity Chromatography written by J. Turková and published by Elsevier. This book was released on 1993-09-14 with total page 819 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioaffinity chromatography is now the preferred choice for the purification, determination or removal of many biologically active substances. The book includes information on biologically active substances with their affinants, solid supports and methods of coupling, summarized in tables covering classical, high-performance liquid and large-scale bioaffinity chromatography.Optimization of the preparation and the use of highly active and stable biospecific adsorbents is discussed in several chapters. Following a chapter dealing with the choice of affinity ligands, affinity-sorbent bonding is described in detail. Other chapters give information on solid supports, the most common coupling procedures and a general discussion of sorption and elution. Several applications of bioaffinity chromatography are described, e.g. quantitative evaluation of biospecific complexes and many applications in medicine and in the biotechnology industry.
Author : Dolph L. Hatfield
Publisher : CRC Press
ISBN 13 : 1351085840
Total Pages : 446 pages
Book Rating : 4.3/5 (51 download)
Download or read book Transfer RNA in Protein Synthesis written by Dolph L. Hatfield and published by CRC Press. This book was released on 2018-01-10 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transfer RNA in Protein Synthesis is a comprehensive volume focusing on important aspects of codon usage, selection, and discrimination in the genetic code. The many different functions of tRNA and the specialized roles of the corresponding codewords in protein synthesis from initiation through termination are thoroughly discussed. Variations that occur in the initiation process, in reading the genetic code, and in the selection of codons are discussed in detail. The book also examines the role of modified nucleosides in tRNA interactions, tRNA discrimination in aminoacylation, codon discrimination in translation, and selective use of termination codons. Other topics covered include the adaptation of the tRNA population to codon usage in cells and cellular organelles, the occurence of UGA as a codon for selenocysteine in the universal genetic code, new insights into translational context effects and in codon bias, and the molecular biology of tRNA in retroviruses. The contributions of outstanding molecular biologists engaged in tRNA research and prominent investigators from other scientific disciplines, specifically retroviral research, make Transfer RNA in Protein Synthesis an essential reference work for microbiologists, biochemists, molecular biologists, geneticists, and other researchers involved in protein synthesis research.
Author :
Publisher : Elsevier
ISBN 13 : 0080858597
Total Pages : 663 pages
Book Rating : 4.0/5 (88 download)
Download or read book Applications written by and published by Elsevier. This book was released on 1991-11-26 with total page 663 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications
Author : Z. El Rassi
Publisher : Elsevier
ISBN 13 : 008085866X
Total Pages : 693 pages
Book Rating : 4.0/5 (88 download)
Download or read book Carbohydrate Analysis written by Z. El Rassi and published by Elsevier. This book was released on 1994-11-11 with total page 693 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrates and glycoconjugates play an important role in several life processes. The wide variety of carbohydrate species and their inherent polydispersity and heterogeneity require separation techniques of high resolving power and high selectivity such as high performance liquid chromatography (HPLC) and capillary electrophoresis (HPCE). In the last decade HPLC, and recently HPCE methods have been developed for the high resolution and reproducible quantitation of carbohydrates. Despite the importance of these two column separation technologies in the area of carbohydrates, no previous book describes specialized methods for the separation, purification and detection of carbohydrates and glycoconjugates by HPLC and HPCE.Therefore, the objective of the present book is to provide a comprehensive review of carbohydrate analysis by HPLC and HPCE by covering analytical and preparative separation techniques for all classes of carbohydrates including mono- and disaccharides; linear and cyclic oligosaccharides; branched heterooligosaccharides (e.g., glycans, plant-derived oligosaccharides); glycoconjugates (e.g., glycolipids, glycoproteins); carbohydrates in food and beverage; compositional carbohydrates of polysaccharides; carbohydrates in biomass degradation; etc.The book will be of interest to a wide audience, including analytical chemists and biochemists, carbohydrate, glycoprotein and glycolipid chemists, molecular biologists, biotechnologists, etc. It will also be a useful reference work for both the experienced analyst and the newcomer as well as for users of HPLC and HPCE, graduates and postdoctoral students.
