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Chromatographic Processes
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Book Synopsis Principles and Practice of Modern Chromatographic Methods by : Kevin Robards
Download or read book Principles and Practice of Modern Chromatographic Methods written by Kevin Robards and published by Academic Press. This book was released on 2021-12-03 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Practice of Modern Chromatographic Methods, Second Edition takes a comprehensive, unified approach in its presentation of chromatographic techniques. Like the first edition, the book provides a scientifically rigid, but easy-to-follow presentation of chromatography concepts that begins with the purpose and intent of chromatographic theory - the “what and why that are left out of other books attempting to cover these principles. This fully revised second edition brings the content up-to-date, covering recent developments in several new sections and an additional chapter on composite methods. New topics include sample profiling, sample preparation, sustainable green chemistry, 2D chromatography, miniaturization/nano-LC, HILIC, and more. Contains thorough chapters that begin with an updated schematic overview and a visual representation of the content Avoids the obfuscation of different terminologies and classification systems that are prevalent in the area, such as the relationship between liquid chromatography and column chromatography Provides integrated and comprehensive topic coverage based on chromatographic bibliometrics and survey reports on the relative usage of chromatographic techniques
Book Synopsis Chromatographic Processes by : Roger-Marc Nicoud
Download or read book Chromatographic Processes written by Roger-Marc Nicoud and published by Cambridge University Press. This book was released on 2015-04-20 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: A result-oriented, practical guide to key approaches, methodologies and tools for designing, modelling and simulating chromatographic processes.
Book Synopsis Validating Chromatographic Methods by : David M. Bliesner
Download or read book Validating Chromatographic Methods written by David M. Bliesner and published by John Wiley & Sons. This book was released on 2006-09-11 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: All the information and tools needed to set up a successful method validation system Validating Chromatographic Methods brings order and Current Good Manufacturing Practices to the often chaotic process of chromatographic method validation. It provides readers with both the practical information and the tools necessary to successfully set up a new validation system or upgrade a current system to fully comply with government safety and quality regulations. The net results are validated and transferable analytical methods that will serve for extended periods of time with minimal or no complications. This guide focuses on high-performance liquid chromatographic methods validation; however, the concepts are generally applicable to the validation of other analytical techniques as well. Following an overview of analytical method validation and a discussion of its various components, the author dedicates a complete chapter to each step of validation: Method evaluation and further method development Final method development and trial method validation Formal method validation and report generation Formal data review and report issuance Templates and examples for Methods Validation Standard Operating Procedures, Standard Test Methods, Methods Validation Protocols, and Methods Validation Reports are all provided. Moreover, the guide features detailed flowcharts and checklists that lead readers through every stage of method validation to ensure success. All of the templates are also included on a supplementary support site, enabling readers to easily work with and customize them. For scientists and technicians new to method validation, this guide provides all the information and tools needed to develop a top-quality system. For those experienced with method validation, the guide helps to upgrade and improve existing systems.
Book Synopsis Chromatographic Methods in Metabolomics by : Tuulia Hyotylainen
Download or read book Chromatographic Methods in Metabolomics written by Tuulia Hyotylainen and published by Royal Society of Chemistry. This book was released on 2013-09-06 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of a metabolic profile was introduced in 1971, when gas chromatography demonstrated a range of compounds present in human samples. Now termed metabolomics, the field is still emerging, and chromatography remains an essential tool for determining metabolites in a living system. This is the first book to present the chromatographic techniques used in metabolomics in a fundamental way. Sample preparation and quality control are described in detail, and all forms of chromatography applied to metabolomics are included. The editors present guidelines on selecting the most appropriate methodology, making the book an accessible guide to anyone entering the field. Handling data and applications are also described. This is an essential handbook for any laboratory looking to embark on a metabolomics research programme and includes the fundamentals of chromatography alongside the latest developments in the field.
Book Synopsis Chromatographic Methods in Clinical Chemistry and Toxicology by : Roger Bertholf
Download or read book Chromatographic Methods in Clinical Chemistry and Toxicology written by Roger Bertholf and published by John Wiley & Sons. This book was released on 2007-01-30 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to fill the gap that exists between theoretical treatments of chromatography, and clinical chemistry and toxicology texts, which focus almost exclusively on clinical relevance and applications. Chromatography has a vast array of clinical applications, and though the chromatographic methods were first introduced decades ago, new applications of this technology are being used to explore previously inaccessible frontiers in clinical diagnostics and toxicological testing. An up-to-date book devoted to clinical and toxicological applications of chromatographic methods will serve as an instructional and reference text, useful to students, laboratory technicians, and researchers.
Book Synopsis Preparative Chromatography by : H. Schmidt-Traub
Download or read book Preparative Chromatography written by H. Schmidt-Traub and published by John Wiley & Sons. This book was released on 2012-09-27 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and substantially extended to reflect the developments in this fast-changing field. It retains the interdisciplinary approach that elegantly combines the chemistry and engineering involved to describe the conception and improvement of chromatographic processes. It also covers recent advances in preparative chromatographic processes for the separation of "smaller" molecules using standard laboratory equipment as well as the detailed conception of industrial chemical plants. The increase in biopharmaceutical substances is reflected by new and revised chapters on different modifications of continuous chromatography as well as ion-exchange chromatography and other separation principles widely used in biochromatography. Following an introductory section on the history of chromatography, the current state of research and the design of chromatographic processes, the book goes on to define the general terminology. There then follow sections on stationary phases, selection of chromatographic systems and process concepts. A completely new chapter deals with engineering and operation of chromatographic equipment. Final chapters on modeling and determination of model parameters as well as model based design, optimization and control of preparative chromatographic processes allow for optimal selection of chromatographic processes. Essential for chemists and chemical engineers in the chemical, pharmaceutical, and food industries.
Book Synopsis Protein Chromatography by : Giorgio Carta
Download or read book Protein Chromatography written by Giorgio Carta and published by John Wiley & Sons. This book was released on 2020-06-02 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: An all-in-one practical guide on how to efficiently use chromatographic separation methods Based on a training course that teaches the theoretical as well as practical aspects of protein bioseparation to bioprocess professionals, this fully updated and revised new edition offers comprehensive coverage of continuous chromatography and provides readers with many relevant examples from the biopharmaceutical industry. Divided into two large parts, Protein Chromatography: Process Development and Scale-Up, Second Edition presents all the necessary knowledge for effective process development in chromatographic bioseparation, both on small and large scale. The first part introduces chromatographic theory, including process design principles, to enable the reader to rationalize the set-up of a bioseparation process. The second part illustrates by way of case studies and sample protocols how the theory learned in the first part may be applied to real-life problems. Chapters look at: Downstream Processing of Biotechnology Products; Chromatography Media; Laboratory and Process Columns and Equipment; Adsorption Equilibrium; Rate Processes; and Dynamics of Chromatography Columns. The book closes with chapters on: Effects of Dispersion and Rate Processes on Column Performance; Gradient Elution Chromatography; and Chromatographic Column Design and Optimization. -Presents the most pertinent examples from the biopharmaceutical industry, including monoclonal antibodies -Provides an overview of the field along with design tools and examples illustrating the advantages of continuous processing in biopharmaceutical productions -Focuses on process development and large-scale bioseparation tasks, making it an ideal guide for the professional bioengineer in the biotech and pharma industries -Offers field-tested information based on decades of training courses for biotech and chemical engineers in Europe and the U.S. Protein Chromatography: Process Development and Scale-Up, Second Edition will appeal to biotechnologists, analytical chemists, chromatographers, chemical engineers, pharmaceutical industry, biotechnological industry, and biochemists.
Book Synopsis Chromatographic Processes by : Roger-Marc Nicoud
Download or read book Chromatographic Processes written by Roger-Marc Nicoud and published by Cambridge University Press. This book was released on 2015-04-20 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addressing all aspects of the design, modeling and simulation of chromatographic processes, this result-oriented primer provides a practical guide to all the necessary approaches, methodologies and tools. Beginning with key definitions and concepts, it builds up from the most simple to the most complex situations, including multicomponent systems, non-uniform velocity profiles, bed instability, particle size distributions, and the influence of complex environments on chromatographic process design. In addition to covering classical approaches, it introduces efficient tools for investigating chromatographic processes, such as the 'Russian-Lego' approach for linear systems, phenomenological models, and specific shortcuts for deriving the key properties of industrial processes. With an emphasis on real-world problems and applications, step-by step modeling design guidelines, and detailed exercises for self-assessment, this is a must-have guide for practitioners and researchers working in chemical, biochemical, food and pharmaceutical engineering.
Book Synopsis Chromatographic Methods by : A. Braithwaite
Download or read book Chromatographic Methods written by A. Braithwaite and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a unified and balanced introduction to the general theory of chromatography, followed by a detailed treatment of the principles and practice of all the major techniques currently employed in the industrial and academic sectors. It is written as a broad introduction to the subject for mid to advanced undergraduates in chemistry, pharmacy, biochemistry, and is suitable for students following the now quite numerous Masters degrees in instrumental analysis. The book has been updated to incorporate advances of the last ten years, and it contains around 50% new or revised material.
Book Synopsis Handbook of Process Chromatography by : Gunter Jagschies
Download or read book Handbook of Process Chromatography written by Gunter Jagschies and published by Elsevier. This book was released on 2007-12-08 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will update the original edition published in 1997. Since the publication of the first edition, the biotechnology and biologics industries have gained extensive knowledge and experience in downstream processing using chromatography and other technologies associated with recovery and purification unit operations. This book will tie that experience together for the next generation of readers. Updates include: - sources and productivity - types of products made today - experiences in clinical and licensed products - economics - current status of validation - illustrations and tables - automated column packing - automated systems New topics include: - the use of disposables - multiproduct versus dedicated production - design principles for chromatography media and filters - ultrafiltration principles and optimization - risk assessments - characterization studies - design space - platform technologies - process analytical technologies (PATs) - biogenerics - comparability assessments Key Features: - new approaches to process optimiaztion - use of patform technologies - applying risk assessment to process design
Book Synopsis Chromatographic and Membrane Processes in Biotechnology by : C.A. Costa
Download or read book Chromatographic and Membrane Processes in Biotechnology written by C.A. Costa and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Separation processes in biotechnology are of increasing industrial importance since they entail the major costs of bioprocessing especially when high purity is required. Chromatography and membranes are two of the most important technologies used for direct treatment of fermentation broths as well as for high resolution steps in product purification. The theoretical foundations of chromatographic and membrane processes are well understood for the case of small molecules. Nevertheless there is a need to adapt and further develop that knowledge to the processing of large biological molecules. This is being achieved with the contribution of other areas like molecular biology and materials science. The objective of this NATO Advanced Study Institute is to present an updated treatment of the fundamentals of chromatographic and membrane processes with special relevance in bioprocessing.This volume collects the lectures presented at this Institute. The lectures are arranged in five chapters. Chapter I deals with chromatographic processes covering topics like equilibrium, kinetics and contacting devices. Membrane processes and some applications in biotechnology are treated in chapter 2. Chapter 3 is devoted to affinity chromatographic and membrane processes. Chapter 4 considers the current developments on chromatographic supports and membranes both from the constitutive materials and form points of view. Scale-up, optimization and reaction/separation integration are the topics covered in chapter 5. We are very grateful to all lecturers and participants that made possible this Institute. Financial support from NATO Scientific Affairs Division, INIC, JNICT, FLAD, University of Ac;ores and DRT Ac;ores is gratefully acknowledged.
Download or read book Chromatography written by and published by Elsevier. This book was released on 2011-08-26 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromatography
Book Synopsis Handbook of Thin-Layer Chromatography by : Joseph Sherma
Download or read book Handbook of Thin-Layer Chromatography written by Joseph Sherma and published by CRC Press. This book was released on 2003-04-18 with total page 1356 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this third edition, more than 40 renowned authorities introduce and update chapters on the theory, fundamentals, techniques, and instrumentation of thin-layer chromatography (TLC) and high-performance thin-layer chromatography (HPTLC), highlighting the latest procedures and applications of TLC to 19 important compound classes and coverage of TLC applications by compound type. Easily adaptable to industrial scenarios , the Handbook of Thin-Layer Chromatography, Third Edition supports practical research strategies with extensive tables of data, offers numerous figures that illustrate techniques and chromatograms, and includes a glossary as well as a directory of equipment suppliers.
Book Synopsis Chromatographic Methods Development by : Gregory K. Webster
Download or read book Chromatographic Methods Development written by Gregory K. Webster and published by CRC Press. This book was released on 2019-10-28 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive compilation of modern and cutting-edge chromatographic techniques written by pharmaceutical industry experts, academics, and vendors in the field. This book is an inclusive guide to developing all chromatographic methods (such as liquid chromatography and gas chromatography). It covers modern techniques for developing methods using chromatographic development software, requirements for validations, discussion on orthogonality, and how to transfer methods from HPLC to UHPLC. The text introduces some newer techniques that are heavily employed by chemists analyzing proteins and RNAi, as well as novel techniques such as counter current chromatography. This book is valuable for both the novice starting out in undergraduate labs and those who are new to the pharmaceutical industry and is a useful reference for seasoned analysts.
Book Synopsis Preparative Chromatography by : H. Schmidt-Traub
Download or read book Preparative Chromatography written by H. Schmidt-Traub and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: This interdisciplinary approach combines the chemistry and engineering involved to describe the conception and improvement of chromatographic processes. The book covers recent developments in preparative chromatographic processes for the separation of "smaller" molecules using standard laboratory equipment as well as the detailed conception of industrial chemical plants. Following an introductory section on the history of chromatography, the current state of research and the design of chromatographic processes, the book goes on to define the general terminology. There then follow sections on solid materials and packed columns process concepts. Final chapters on modeling and determination of model parameters, the design and optimization of preparative chromatographic processes and chromatographic reactors allow for the optimum selection of chromatographic systems. Essential for chemists and engineers working in the chemicals and pharmaceutical industries as well as for food technologies, due to the interdisciplinary nature of these processes.
Book Synopsis Sample Preparation in Chromatography by : S.C. Moldoveanu
Download or read book Sample Preparation in Chromatography written by S.C. Moldoveanu and published by Elsevier. This book was released on 2002-05-08 with total page 949 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sample preparation is an essential step in many analyses. This book approaches the topic of sample preparation in chromatography in a methodical way, viewing it as a logical connection between sample collection and analytical chromatography. Providing a guide for choosing the appropriate sample preparation for a given analysis, this book describes various ways to process the sample, explaining the principle, discussing the advantages and disadvantages, describing the applicability to different types of samples, and showing the fitness to specific chromatographic determinations. The first part of the book contains an overview of sample preparation showing its relation to sample collection and to the core chromatographic analysis. The second part covers procedures that do not use chemical modifications of the analyte and includes methods for sample dissolution, concentration and cleanup designed mainly for modifying the initial matrix of the sample. This part starts with conventional separations such as filtration and distillation and finishes with more advanced techniques such as solid phase extraction and electroseparations. The third part gives a description of the chemical modifications that can be performed on a sample either for fractionation purposes or to improve a specific property of the analyte. This part includes derivatizations, polymer chemical degradations, and pyrolysis.
Book Synopsis Techniques and Practice of Chromatography by : Raymond P.W. Scott
Download or read book Techniques and Practice of Chromatography written by Raymond P.W. Scott and published by CRC Press. This book was released on 2020-01-29 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work introduces scientists of all disciplines to the chromatographic process and how it functions. The basic principles of chromatographic separation and specific chromatographic procedures, including gas, liquid and thin-layer chromatography, are covered. For each separation method the book details its characteristics, the instrumentation required, the procedures necessary for effective use, areas of application and examples of its use.;This work is intended for analytical chemists, laboratory technicians, and upper-level undergraduate and graduate students in analytical chemistry or separation science courses.
