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Cholesterol Autoxidation
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Book Synopsis Cholesterol Autoxidation by : Leland L. Smith
Download or read book Cholesterol Autoxidation written by Leland L. Smith and published by Springer Science & Business Media. This book was released on 2013-11-22 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most components of the biosphere are continuously ex posed to oxygen from the atmosphere. Accordingly, the inex orable deterioration of all organic compounds by the slow attack of oxygen must occur. Despite this eventuality, a definitive treatment of oxygen-dependent decomposition of any single important natural product has not heretofore been made. The instant monograph attempts to provide a complete description of the autoxidation of one such impor tantnatural product, cholesterol, as the matter is currently understood. The autoxidation of cholesterol in Nature has been a matter of interest to others since the close of the nine teenth century and to me for the past three decades. In this monograph I present aspects of what I have learned about cholesterol autoxidation during that interval. Be cause of the diffuse ann troublesoae nature of the subject I have selected to cite references to the literature rather fully, so that all items discussed may be properly evaluated by the interested reader. Though such extensive citation of references makes for labored reading, I hope the text will serve as a definitive treatment of the subject from which other studies may be engendered without extensive recourse to the older material. An .attempt has been made to include much related in formation so that a detailed awareness of the interrelation ships between cholesterol autoxidation and other aspects of chemistry, metabolism, and toxicology may be had. I risk teaching more on the subject than any reader care to learn.
Book Synopsis Autoxidation in Food and Biological Systems by : M.G. Simic
Download or read book Autoxidation in Food and Biological Systems written by M.G. Simic and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: The material presented in this book deals with basic mechanisms of free radical reactions in autoxidation processes and anitoxidant suppression of autoxidation of foods, biochemical models and biologi cal systems. Autoxidation in foods and corresponding biological effects are usually approached separately although recent mechanistic developments in the biochemistry and free radical chemistry of per oxides and their precursors tend to bring these two fields closer. Apparent ability of antioxidants in diets to reduce the inci dence of cancer has resulted in scrutiny of autoxidized products and their precursors as possibly toxic, mutagenic and carcinogenic agents. Mechanisms of any of these effects have been barely ad dressed. Yet we know now that free radicals, as esoteric as they were only a few decades ago, are being discovered in foods, biochem ical and biological systems and do play a role in the above-mentioned causalities. The purpose of the Workshop and the resulting book was to give a unifying approach towards study of beneficial and deleterious effects of autoxidation, based on rigorous scientific considerations. It is our hope that the material presented in this book will not only provide a review of the "state of the art" of autoxidation and anti oxidants, but also reflect the interaction which occurred during the Workshop between workers using model sytems, and food and biological systems.
Book Synopsis Biological Effects of Cholesterol Oxides by : Shi-Kaung Peng
Download or read book Biological Effects of Cholesterol Oxides written by Shi-Kaung Peng and published by CRC Press. This book was released on 1991-11-22 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, researchers have accumulated a growing body of evidence linking cholesterol oxides with human diseases such as atherosclerosis and cancer. This book presents what is presently known about the biological activities of cholesterol oxides and is intended to stimulate thinking in new areas of diet-heart or diet-cancer research. Topics discussed include the oxidation of cholesterol, methods of analysis of cholesterol oxides, cholesterol oxide content in foods, effects of cholesterol oxides on cell membranes, and cytotoxicity of cholesterol oxides. The book will be an essential reference source for researchers working directly with cholesterol and cholesterol oxides, as well as researchers concerned with the wider aspects of chemistry, biology, and medicine.
Book Synopsis Autoxidation of Unsaturated Lipids by : H. W.-S. Chan
Download or read book Autoxidation of Unsaturated Lipids written by H. W.-S. Chan and published by . This book was released on 1987 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Lipid Oxidation by : Edwin N. Frankel
Download or read book Lipid Oxidation written by Edwin N. Frankel and published by Elsevier. This book was released on 2014-01-23 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this second edition, Edwin Frankel has updated and extended his now well-known book Lipid oxidation which has come to be regarded as the standard work on the subject since the publication of the first edition seven years previously. His main objective is to develop the background necessary for a better understanding of what factors should be considered, and what methods and lipid systems should be employed, to achieve suitable evaluation and control of lipid oxidation in complex foods and biological systems. The oxidation of unsaturated fatty acids is one of the most fundamental reactions in lipid chemistry. When unsaturated lipids are exposed to air, the complex, volatile oxidation compounds that are formed cause rancidity. This decreases the quality of foods that contain natural lipid components as well as foods in which oils are used as ingredients. Furthermore, products of lipid oxidation have been implicated in many vital biological reactions, and evidence has accumulated to show that free radicals and reactive oxygen species participate in tissue injuries and in degenerative disease. Although there have been many significant advances in this challenging field, many important problems remain unsolved. This second edition of Lipid oxidation follows the example of the first edition in offering a summary of the many unsolved problems that need further research. The need to understand lipid oxidation is greater than ever with the increased interest in long-chain polyunsaturated fatty acids, the reformulation of oils to avoid hydrogenation and trans fatty acids, and the enormous attention given to natural phenolic antioxidants, including flavonoids and other phytochemicals.
Book Synopsis Measuring Oxidants and Oxidative Stress in Biological Systems by : Lawrence J. Berliner
Download or read book Measuring Oxidants and Oxidative Stress in Biological Systems written by Lawrence J. Berliner and published by Springer Nature. This book was released on 2020-08-08 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the methods of analysis and determination of oxidants and oxidative stress in biological systems. Reviews and protocols on select methods of analysis of ROS, RNS, oxygen, redox status, and oxidative stress in biological systems are described in detail. It is an essential resource for both novices and experts in the field of oxidant and oxidative stress biology.
Author :Francesc Guardiola Publisher :The American Oil Chemists Society ISBN 13 :9781893997349 Total Pages :408 pages Book Rating :4.9/5 (973 download)
Book Synopsis Cholesterol and Phytosterol Oxidation Products by : Francesc Guardiola
Download or read book Cholesterol and Phytosterol Oxidation Products written by Francesc Guardiola and published by The American Oil Chemists Society. This book was released on 2002-07-30 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively reviews several aspects of cholesterol oxidation products: cholesterol oxidation mechanisms, analytical determination, origin and content of these compounds in foods and biological samples, and their biological effects, with an emphasis on recent advances in these fields. Information on different aspects of phytosterol oxidation is reviewed. Little research has been conducted on the analysis of mixed sterol oxidation products. Mixed diets containing both cholesterol and phytosterols can contain a complex array of oxidation products generated from these sterols. Research into the problem of analyzing these complex mixtures of compounds is highlighted.
Book Synopsis Lipid Chromatographic Analysis by : Takayuki Shibamoto
Download or read book Lipid Chromatographic Analysis written by Takayuki Shibamoto and published by CRC Press. This book was released on 1993-12-14 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on state-of-the-art gas chromatography (GC) and high-performance liquid chromatography, this guide discusses the theories behind, and applications of, the latest developments in chromatographic techniques - assessing the strengths and limitations of each methodology.;Presenting many detection methods for the first time, Lipid Chromatographic Analysis: provides a review of conventional column and thin-layer chromatography; examines a new GC technique to detect plasmalogen phospholipids; outlines a supercritical fluid chromatography for lipids; details the first systematic description of a microanalytical procedure for cholesterol and related compounds; explains a GC analysis of lipid breakdown products for monitoring biological processes such as ageing, carcinogenesis and mutagenesis; and describes techniques that allow for the simultaneous analysis of non-polar and polar lipids.
Book Synopsis Autoxidation Products of Cholesterol in Aerated Sols and Irradiated Spray-dried Egg Yolk by : Etzer Chicoye
Download or read book Autoxidation Products of Cholesterol in Aerated Sols and Irradiated Spray-dried Egg Yolk written by Etzer Chicoye and published by . This book was released on 1968 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Lipid Peroxides in Biology and Medicine by : Kunio Yagi
Download or read book Lipid Peroxides in Biology and Medicine written by Kunio Yagi and published by Elsevier. This book was released on 2012-12-02 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lipid Peroxides in Biology and Medicine emphasizes the importance of the control of lipid peroxides in the body for the prevention and treatment of degenerative diseases. This book discusses the production of free radicals in vivo from the action of xenobiotics, and comparative aspects of several model lipid peroxidation systems. The lipid peroxidation and membrane alterations in erythrocyte survival, and lipid peroxidations of cholesterol are also deliberated. This text likewise covers the mechanism of protection against membrane peroxidation, lipid peroxides as a cause of vascular diseases, and peroxide-mediated metabolic activation of carcinogens. Other topics include lipid peroxide in aging process and production of ethane and pentane during lipid peroxidation. This publication is valuable to biologists, medical practitioners, and clinicians researching on lipid peroxides.
Book Synopsis Radically Different—A Themed Issue in Honor of Professor Bernd Giese on the Occasion of His 80th Birthday by : Katharina M. Fromm
Download or read book Radically Different—A Themed Issue in Honor of Professor Bernd Giese on the Occasion of His 80th Birthday written by Katharina M. Fromm and published by MDPI. This book was released on 2020-12-02 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue came together thanks to contributions from friends and colleagues of Prof. Bernd Giese on behalf of his 80th birthday on 2 June 2020. Reflecting on the varied interests of Bernd in all areas of chemistry, this issue contains work, including historical work, on inorganic coordination chemistry, nanomaterials, theory, and organic and radical chemistry—Bernd’s core expertise. It is wonderful that so many different publications came together from all over the world, as both review articles and original contributions, making this Special Issue worthwhile reading.
Book Synopsis Oxygen Radicals in Biological Systems by : Lester Packer
Download or read book Oxygen Radicals in Biological Systems written by Lester Packer and published by Elsevier. This book was released on 1994 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since biological tissues are unstable in an oxygen atmosphere, a great deal of effort is expended by organisms to metabolically limit or repair oxidative tissue damage. This volume of Methods in Enzymology and its companion Volume 234 present methods developed to investigate the roles of oxygen radicals and antioxidants in disease. Key Features* Generation, detection, and characterization of oxygen radicals, chemistry, biochemistry, and intermediate states of reductio* Isolation, characterization, and assay of enzymes or substrates involved in formation or removal of oxygen radical* Methods for assessing molecular, cell, and tissue damage; assays and repair of oxidative damage.
Book Synopsis Bioactive Natural Products (Part E) by : Atta-ur Rahman
Download or read book Bioactive Natural Products (Part E) written by Atta-ur Rahman and published by Elsevier. This book was released on 2000-12-22 with total page 1171 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. The significance, therefore, of the Studies in Natural Product Chemistry series, edited by Professor Atta-ur-Rahman, cannot be overestimated. This volume, in accordance with previous volumes, presents us with cutting-edge contributions of great importance.
Book Synopsis Free Radicals, Lipoproteins, and Membrane Lipids by : A. Crastes de Paulet
Download or read book Free Radicals, Lipoproteins, and Membrane Lipids written by A. Crastes de Paulet and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the proceedings of the ARW NATO Conference on "Action of Free Radicals and Active Forms of Oxygen on Lipoproteins and Membrane Lipids: Cellular Interactions and Atherogenesis", held in Bendor, France, October 5-8,1988. Since the pioneer work of Mc Cord and Fridovitch, growing interest has been focused on the study of the role of oxyradicals role in pathology. This interest is reflected in the exponential increase in the number of papers on free radicals, the success of specialized journals and books on this theme, and the organization of national and international meetings. These meetings have discussed, from.a broad point of view, the problems concerning the mechanisms of production of free radicals, their effects on cell CO!1$tituants (lipids, proteins, nucleic acids) and cell function, the methods of analysis of these phenomena, the pathological states in which free radicals may be involved, natural biological defense systems, and the design of "antiradical" therapies. But it is now well established that the most common target of oxy free radicals are membrane lipids because of their chemical nature (cholesterol in saturation, malonic linkage of polyunsaturated fatty acids (PUFA» and of their regular structural arrangement (monolayers in lipoproteins, bilayers in cell membranes). Thus the analysis of the products resulting from the action of oxy free radicals on PUFA is considered the best tool to indirectly evaluate the effects of tissue peroxidations, although the analytical basis for doing so is very questionable.
Book Synopsis Lipid Analysis in Oils and Fats by : R.J. Hamilton
Download or read book Lipid Analysis in Oils and Fats written by R.J. Hamilton and published by Springer Science & Business Media. This book was released on 1998 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the developments in the field of lipid analysis, providing an up-to-date review of the analytical techniques available to chemists and technologists to identify complex molecules. The requisite theoretical background will be provided for individual techniques, together with their strengths and weaknesses, and a guide to the enormous range of commercial applications. It will be an invaluable reference source to all sectors of the oils and fats industry where accurate labeling of foods, food contamination and adulteration are issues of increasing interest and concern.
Book Synopsis Biomarkers for Antioxidant Defense and Oxidative Damage by : Giancarlo Aldini
Download or read book Biomarkers for Antioxidant Defense and Oxidative Damage written by Giancarlo Aldini and published by John Wiley & Sons. This book was released on 2011-06-09 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers for Antioxidant Defense and Oxidative Damage: Principles and Practical Applications critically evaluates the basic concepts and methodologies of conventional biomarkers as well as current state-of-the-art assays for measuring antioxidant activity/oxidative stress and their practical applications. . Biomarkers for Antioxidant Defense and Oxidative Damage: Principles and Practical Applications will be of a great interest to scientists who are involved in basic research on oxidation, applied scientists evaluating the effects of nutraceuticals or pharmaceutical compounds on antioxidant activity/oxidative stress, and physicians who want to understand the degree of oxidative damage in patients with certain chronic diseases. Discovering sensitive and specific biomarkers for systemic oxidative damage is essential to understand the role of oxidative stress in human disease. Once these roles are clearly understood, we are able to identify novel drug and nutraceutical targets. This volume goes beyond conventional analytical methods of measuring overall antioxidant activity and provides insight to the discovery of biomarkers that reveal information on specific areas of oxidative stress. Contributed by an international list of experts, Biomarkers for Antioxidant Defense and Oxidative Damage: Principles and Practical Applications describes both conventional biomarkers and recent developments in this area. Special Features: Discusses conventional biomarkers as well as recent advances for measuring antioxidants and oxidative stress Biomarkers for lipid peroxidation: isoprostane, hydroxyloctadecaenoic acid, oxysterols, and reactive carbonyl species from lipid peroxidation Biomarkers for protein oxidation: carbonylation, tyrosine oxidation, ubiquitin-conjugation Biomarkers for DNA oxidative damage: comet assay, hydroxylated nucleotides, and exocylcic DNA adducts Recently developed biomarkers from cutting-edge technology
Book Synopsis Impact of Processing on Food Safety by : Lauren S. Jackson
Download or read book Impact of Processing on Food Safety written by Lauren S. Jackson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contents of this book are the proceedings of the ACS symposium, "Impact of Processing on Food Safety," which was held April 16-17, 1997, at the American Chemical Society National Meeting in San Francisco, CA. This symposium brought together re searchers from diverse backgrounds in academia, government, and industry. Twenty speakers discussed topics ranging from the regulatory aspects of food processing to the microbiological and chemical changes in food during processing. The main goal of food processing is to improve the microbial safety of food by de stroying pathogenic and spoilage organisms. Food processing can also improve food safety by destroying or eliminating naturally occurring toxins, chemical contaminants, and antinutritive factors. Unfortunately, processing can also cause chemical changes that result in the formation of toxic or antinutritive factors. The purpose of this book is to summarize our knowledge of both the beneficial and deleterious effects of processing. Chapter I con siders the consumer's perceptions about food contaminants and food processing. Chapter 2 summarizes the effects of traditional and nontraditional processing methods on microor ganisms in food. Chapters 3-6 review the effects of processing on lipids (fatty acids and cholesterol) in food. Changes in the nutritive value of vitamins and minerals as a result of processing are discussed in chapter 7. Chapter 8 concentrates on how processing reduces the allergenicity of some foods.
