Cholesterol And Atherosclerosis

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Stroke Genetics

Author : Hugh S. Markus
Publisher : Oxford Medical Publications
ISBN 13 : 0198515863
Total Pages : 362 pages
Book Rating : 4.1/5 (985 download)

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Book Synopsis Stroke Genetics by : Hugh S. Markus

Download or read book Stroke Genetics written by Hugh S. Markus and published by Oxford Medical Publications. This book was released on 2003 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke is a major cause of death and the major cause of adult neurological disability in most of the world. Despite its importance on a population basis, research into the genetics of stroke has lagged behind that of many other disorders. However, the situation is now changing. Anincreasing number of single gene disorders causing stroke are being described, and there is growing evidence that polygenic factors are important in the risk of apparently "sporadic" stroke.Stroke Genetics provides an up-to-date review of the area, suitable for clinicians treating stroke patients, and both clinical and non-clinical researchers in the field of cerebrovascular disease. The full range of monogenic stroke disorders causing cerebrovascular disease, including ischaemicstroke, intracerebral haemorrhage, aneurysms and arteriovenous malformations, are covered. For each, clinical features, diagnosis, and genetics are described. Increasing evidence suggest that genetic factors are also important for the much more common multifactorial stroke; this evidence isreviewed along with the results of genetic studies in this area. Optimal and novel strategies for investigating multifactorial stroke, including the use of intermediate phenotypes such as intima-media thickness and MRI detected small vessel disease are reviewed. The book concludes by describing apractical approach to investigating patients with stroke for underlying genetic disorders. Also included is a list of useful websites.

Coronary Primary Prevention Trial

Author :
Publisher :
ISBN 13 :
Total Pages : 2 pages
Book Rating : 4.:/5 (2 download)

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Book Synopsis Coronary Primary Prevention Trial by :

Download or read book Coronary Primary Prevention Trial written by and published by . This book was released on 1984 with total page 2 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Textbook of Vascular Medicine

Author : Rhian M. Touyz
Publisher : Springer
ISBN 13 : 3030164810
Total Pages : 503 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Textbook of Vascular Medicine by : Rhian M. Touyz

Download or read book Textbook of Vascular Medicine written by Rhian M. Touyz and published by Springer. This book was released on 2019-08-02 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook focuses on the vascular biology and physiology that underlie vascular disorders in clinical medicine. Vascular biomedicine is a rapidly growing field as new molecular mechanisms of vascular health and disease are unraveled. Many of the major cardiovascular diseases including coronary artery disease, heart failure, stroke and vascular dementia are diseases of the vasculature. In addition vascular injury underpins conditions like kidney failure and cardiovascular complications of diabetes. This field is truly multidisciplinary involving scientists in many domains such as molecular and vascular biology, cardiovascular physiology and pharmacology and immunology and inflammation. Clinically, specialists across multiple disciplines are involved in the management of patients with vascular disorders, including cardiologists, nephrologists, endocrinologists, neurologists and vascular surgeons. This book covers a wide range of topics and provides an overview of the discipline of vascular biomedicine without aiming at in-depth reviews, but rather offering up-to-date knowledge organized in concise and structured chapters, with key points and pertinent references. The structure of the content provides an integrative and translational approach from basic science (e.g. stem cells) to clinical medicine (e.g. cardiovascular disease). The content of this book is targeted to those who are new in the field of vascular biology and vascular medicine and is ideal for medical students, graduate and postgraduate students, clinical fellows and academic clinicians with an interest in the vascular biology and physiology of cardiovascular disease and related pathologies.

Mechanisms of Vascular Disease

Author : Robert Fitridge
Publisher : University of Adelaide Press
ISBN 13 : 1922064009
Total Pages : 589 pages
Book Rating : 4.9/5 (22 download)

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Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge

Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Cholesterol in Atherosclerosis and Coronary Heart Disease

Author : Jean P. Kovala
Publisher : Nova Publishers
ISBN 13 : 9781594543029
Total Pages : 282 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Cholesterol in Atherosclerosis and Coronary Heart Disease by : Jean P. Kovala

Download or read book Cholesterol in Atherosclerosis and Coronary Heart Disease written by Jean P. Kovala and published by Nova Publishers. This book was released on 2005 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cholesterol is a soft, waxy substance found among the lipids (fats) in the bloodstream and in all the body's cells. It's an important part of a healthy body because it's used to form cell membranes, some hormones and is needed for other functions. But a high level of cholesterol in the blood -- hypercholesterolemia -- is a major risk factor for coronary heart disease, which leads to heart attack. Cholesterol and other fats can't dissolve in the blood. They have to be transported to and from the cells by special carriers called lipoproteins. There are several kinds, but the key ones are low-density lipoprotein (LDL) and high-density lipoprotein (HDL) Low-density lipoprotein is the major cholesterol carrier in the blood. If too much LDL cholesterol circulates in the blood, it can slowly build up in the walls of the arteries feeding the heart and brain. Together with other substances it can form plaque, a thick, hard deposit that can clog those arteries. This field is alive with exciting new research in all areas including frontal advances in the areas of managing cholesterol as well as cholesterol lowering drugs. This new book focuses on cholesterol in atherosclerosis and coronary heart disease.

Atherosclerosis: Diet and Drugs

Author : Arnold Eckardstein
Publisher : Springer Science & Business Media
ISBN 13 : 3540276610
Total Pages : 808 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Atherosclerosis: Diet and Drugs by : Arnold Eckardstein

Download or read book Atherosclerosis: Diet and Drugs written by Arnold Eckardstein and published by Springer Science & Business Media. This book was released on 2005-11-02 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular diseases continue to be the leading cause of death in the - jority of industrialized countries. The most frequent underlying pathology, namely atherosclerosis, and its clinical sequelae, namely coronary heart d- ease, cerebrovascular disease and peripheral artery disease, remain common although for a long time we have been made aware of avoidable or mo- ?able etiological factors such as smoking, fat-rich diet or lack of exercise, and although these adverse lifestyle factors have been extensively addressed by population-wide primary prevention programs. Cardiovascular morbidity and mortality also remain high despite successful anti-hypertensive and lipid lowering drug therapies which help to reduce cardiovascular morbidity and mortality by about 30% in both secondary and tertiary prevention settings. This can partly be explained by the increasing life expectancy and growing p- portionofelderly people,especiallyinEuropeandNorthAmerica. Inaddition, the World Health Organization makes the alarming prediction that probably in response to the spreading of western dietary behavior and lack of exercise resulting in an increasing prevalence of diabetes, dyslipidemia and hypert- sion, cardiovascular diseases rather than infectious diseases will become the most frequent cause of death worldwide. This volume of the Handbook of Experimental Pharmacology entitled “Atherosclerosis” is divided into four parts and intends to give an overview on the pathogenesis of atherosclerosis, established treatment and prevention regimen, and of perspectives for the development of new treatment modalities.

The Cholesterol Wars

Author : Daniel Steinberg
Publisher : Elsevier
ISBN 13 : 0080556191
Total Pages : 253 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The Cholesterol Wars by : Daniel Steinberg

Download or read book The Cholesterol Wars written by Daniel Steinberg and published by Elsevier. This book was released on 2011-04-28 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today, in the era of the statins (cholesterol lowering drugs), there is no longer any doubt about the value of lowering blood cholesterol levels. The Cholesterol Wars chronicles the controversy that swirled around the 'lipid hypothesis' of atherosclerosis for so many years. In fact, 'the lower the better' is the position of many clinicians. However, getting to this point has been a long uphill battle marked by heated debate and sometimes violent disagreement. The history of this controversy is told here for its own sake and because remembering it may help us avoid similar mistakes in the future. - Dr. Steinberg and his colleagues have published over 400 papers relating to lipid and lipoprotein metabolism and atherosclerosis reflecting the prominence these authors have in the community - Chronicles the miraculous power of the statins to prevent heart attacks and save lives, of great interest to the many manufacturers of these drugs - Discusses new targets for intervention based on a better understanding of the molecular basis of atherosclerosis

Intestinal Lipid Metabolism

Author : Charles M. Mansbach
Publisher : Springer Science & Business Media
ISBN 13 : 9780306462412
Total Pages : 464 pages
Book Rating : 4.4/5 (624 download)

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Book Synopsis Intestinal Lipid Metabolism by : Charles M. Mansbach

Download or read book Intestinal Lipid Metabolism written by Charles M. Mansbach and published by Springer Science & Business Media. This book was released on 2000-11-30 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was stimulated by the enthusiasm shown by attendees at the meetings in Saxon River, VT, sponsored by the Federation ofAmerican Societies for Experimental Biology (FASEB), on the subject of the intestinal processing of lipids. When these meetings were first started in 1990, the original organizers, two of whom are editors ofthis volume (CMM and PT), had two major goals. The first was to bring together a diverse group ofinvestiga tors who had the common goal of gaining a better understanding of how the intestine ab sorbs lipids. The second was to stimulate the interest of younger individuals whom we wished to recruit into what we believed was an exciting and fruitful area ofresearch. Since that time, the field has opened up considerably with new questions being asked and new an swers obtained, suggesting that our original goals for the meetings were being met. In the same spirit, it occurred to us that there has not been a recentbook that draws to gethermuch ofthe informationavailableconcerninghow the intestineprocesses lipids. This book is intended to reach investigators with an interest in this area and their pre- and post doctoral students. The chapters are written by individuals who have a long-term interest in the areas about which they write, and many have been speakers at the subsequent FASEB conferences that have followed on the first.

Lipids and Atherosclerosis

Author : Chris J. Packard
Publisher : CRC Press
ISBN 13 : 1135401322
Total Pages : 311 pages
Book Rating : 4.1/5 (354 download)

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Book Synopsis Lipids and Atherosclerosis by : Chris J. Packard

Download or read book Lipids and Atherosclerosis written by Chris J. Packard and published by CRC Press. This book was released on 2005-09-08 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: New discoveries in genetics, molecular, and cell biology are not only enhancing our understanding of the etiology and progression of disease, but are finding applications in the development of new drugs or the implementation of new kinds of therapy. This book provides an in-depth review of emerging areas in biomedical research at the interface of s

The Cholesterol Controversy

Author : Gilbert R. Thompson
Publisher :
ISBN 13 : 9781853158025
Total Pages : 0 pages
Book Rating : 4.1/5 (58 download)

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Book Synopsis The Cholesterol Controversy by : Gilbert R. Thompson

Download or read book The Cholesterol Controversy written by Gilbert R. Thompson and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cholesterol Controversy recounts the long-running debate surrounding the relationship between cholesterol and coronary heart disease. Focusing primarily on events in the UK and the personalities involved, the story is unraveled here, from the origins of the controversy in the 1950s, to the discovery, development and trials of statins in the 1970s, 80s and 90s, culminating with recent concerns over the efficacy of ezetimibe and safety of torcetrapib.

Atherosclerosis and Cardiovascular Disease

Author : G.C. Descovich
Publisher : Springer Science & Business Media
ISBN 13 : 9400907311
Total Pages : 718 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Atherosclerosis and Cardiovascular Disease by : G.C. Descovich

Download or read book Atherosclerosis and Cardiovascular Disease written by G.C. Descovich and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advances in the field of atherosclerosis and cardiovascular disease continue at an increasingly rapid pace and it is an arduous task for those not directly involved to keep up with the latest developments. The papers presented at the 7th Meeting on Atherosclerosis and Cardiovascular Disease, held in Bologna, as part of the Ninth Centenary of the foundation of the University of Bologna, have been collected together here with the aim of providing all the latest information for doctors and research workers concerned with this important branch of medicine. We are pleased to be able to thank all those who joined us in celebrating the oldest university in the world. The scientific contributions, of the highest level, are valid proof of the tradition of exchanging experiences and of the continual up-dating of knowledge in the different sectors of lipid metabolism, genetics, physiopathology, pathological anatomy, bio chemical and clinical diagnosis, diet, pharmacological and non-pharmacological ther apy. The numerous contributions made by authors in the field of epidemiology and the prevention of atherosclerosis were also fundamental since not only research centres but also doctors all over the world are engaged in the battle which was defined by the WHO, twenty-five years ago, as the most important epidemic of the modern age.

Atherosclerosis, Arteriosclerosis and Arteriolosclerosis

Author : Luigi Gianturco
Publisher : BoD – Books on Demand
ISBN 13 : 1838803033
Total Pages : 86 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Atherosclerosis, Arteriosclerosis and Arteriolosclerosis by : Luigi Gianturco

Download or read book Atherosclerosis, Arteriosclerosis and Arteriolosclerosis written by Luigi Gianturco and published by BoD – Books on Demand. This book was released on 2020-05-20 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: With high morbidity and mortality rates, atherosclerosis (ATS) is a major concern worldwide. This book provides comprehensive information on ATS, including chapters on cardiovascular disease and obstructive sleep apnea, rheumatology and cardiovascular risk, and the differences of ATS among men and women. Let’s hope for the best and thank you to all my team for collaborating in this book production. In particular, thanks • to Bruno (my expert colleague) and Aurel (my secretary) for analyzing and reading with me all the texts • to Vincenzo, Stefano and Andrea for English evaluation • and finally to Rebecca (my future wife) for sustaining me in all professional activities giving me power in daily life!

The Great Cholesterol Myth, Revised and Expanded

Author : Jonny Bowden
Publisher : Fair Winds Press
ISBN 13 : 1592339336
Total Pages : 243 pages
Book Rating : 4.5/5 (923 download)

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Book Synopsis The Great Cholesterol Myth, Revised and Expanded by : Jonny Bowden

Download or read book The Great Cholesterol Myth, Revised and Expanded written by Jonny Bowden and published by Fair Winds Press. This book was released on 2020-08-04 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: The best-selling book on heart disease, updated with the latest research and clinical findings on high-fat/ketogenic diets, sugar, genetics, and other factors. Heart disease is the #1 killer. However, traditional heart disease protocols—with their emphasis on lowering cholesterol—have it all wrong. Emerging science is showing that cholesterol levels are a poor predictor of heart disease and that standard prescriptions for lowering it, such as ineffective low-fat/high-carb diets and serious, side-effect-causing statin drugs, obscure the real causes of heart disease. Even doctors at leading institutions have been misled for years based on creative reporting of research results from pharmaceutical companies intent on supporting the $31-billion-a-year cholesterol-lowering drug industry. The Great Cholesterol Myth reveals the real culprits of heart disease, including: inflammation, fibrinogen, triglycerides, homocysteine, belly fat, triglyceride to HDL ratios, and high glycemic levels. Best-selling health authors Jonny Bowden, PhD, and Stephen Sinatra, MD, give readers a four-part strategy based on the latest studies and clinical findings for effectively preventing, managing, and reversing heart disease, focusing on diet, exercise, supplements, and stress and anger management. Myths vs. Facts Myth: High cholesterol is the cause of heart disease. Fact: Cholesterol is only a minor player in the cascade of inflammation which is a cause of heart disease. Myth: Saturated fat is dangerous. Fact: Saturated fats are not dangerous. The killer fats are the transfats from partially hydrogenated oils. â?? Myth: The higher the cholesterol, the shorter the lifespan. Fact: Higher cholesterol protects you from gastrointestinal disease, pulmonary disease, and hemorrhagic stroke. Myth: High cholesterol is a predictor of heart attack. Fact: There is no correlation between cholesterol and heart attacks. Myth: Lowering cholesterol with statin drugs will prolong your life. Fact: There is no data to show that statins have a significant impact on longevity. Myth: Statin drugs are safe. Fact: Statin drugs can be extremely toxic including causing death. Myth: Statin drugs are useful in men, women, and the elderly. Fact: Statin drugs do the best job in middle-aged men with coronary disease. Myth: Statin drugs are useful in middle-aged men with coronary artery disease because of its impact on cholesterol. Fact: Statin drugs reduce inflammation and improve blood viscosity (thinning blood). Statins are extremely helpful in men with low HDL and coronary artery disease.

Vascular Diseases for the Non-Specialist

Author : Tulio Pinho Navarro
Publisher : Springer
ISBN 13 : 3319460595
Total Pages : 279 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Vascular Diseases for the Non-Specialist by : Tulio Pinho Navarro

Download or read book Vascular Diseases for the Non-Specialist written by Tulio Pinho Navarro and published by Springer. This book was released on 2017-01-03 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to provide non-specialist healthcare practitioners with current, focused and objective information on the most common vascular diseases encountered in daily clinical practice. In day-to-day clinical practice many healthcare practitioners do not have a working knowledge of the most common vascular diseases that frequently arise in patient care. Some of these topics include: aneurysms, peripheral arterial disease, diabetic foot, venous thromboembolism, cerebrovascular disease, aortic dissection, and acute limb ischemia. These commonly encountered vascular diseases are becoming public health issues due to their high morbidity and mortality as well as increasing healthcare costs. Since patients with vascular diseases are often referred to non-specialists, the general practitioner must know how to proper handle the most common vascular diseases encountered in daily clinical practice. For each disease the concept, epidemiology, natural history, diagnosis and treatment are described, followed by essential advice on what the non-specialist can do for the patient and when to refer the patient to a specialist.

Lipoproteins and Atherosclerosis

Author : Claude L. Malmendier
Publisher : Springer Science & Business Media
ISBN 13 : 146841268X
Total Pages : 248 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Lipoproteins and Atherosclerosis by : Claude L. Malmendier

Download or read book Lipoproteins and Atherosclerosis written by Claude L. Malmendier and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atherosclerosis which accounts in Western Europe for more than 40 % of deaths, is a generalized disease that develops slowly and is symptomless until lesions have become sufficiently severe to cause myocardial or cerebral infarction. Research on specific and precocious markers of atherosclerosis and the development of non invasive techniques for their early detection represent major challenges in biomedical field. We hope that this volume of edited papers, a consequence of the third international colloquium on atherosclerosis, conducted at the University of Brussels, Belgium through the support of the "Fondation de Recherche sur l' AtherosclE,rose" will contribute to this goal. Among the topics discussed the major ones were the mechanism of action of lipolytic enzymes, the deficiency or dysregulation of cellular receptors, the genetic deficiencies of apolipoproteins, and the panoply of external factors as diet, physical exercise, drugs, which mOdify the lipoprotein metabolism. Special interest was also devoted to potent techniques as kinetic analysis of metabolic tracers and use of monoclonal antibodies. Their contribution to the detection and treatment of atherosclerosis will be obviously essential in the future.

The Cholesterol Myths

Author : Uffe Ravnskov
Publisher : New Trends Publishing
ISBN 13 : 9780967089713
Total Pages : 0 pages
Book Rating : 4.0/5 (897 download)

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Book Synopsis The Cholesterol Myths by : Uffe Ravnskov

Download or read book The Cholesterol Myths written by Uffe Ravnskov and published by New Trends Publishing. This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

High Density Lipoproteins

Author : Arnold von Eckardstein
Publisher : Springer
ISBN 13 : 9783319096643
Total Pages : 0 pages
Book Rating : 4.0/5 (966 download)

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Book Synopsis High Density Lipoproteins by : Arnold von Eckardstein

Download or read book High Density Lipoproteins written by Arnold von Eckardstein and published by Springer. This book was released on 2015-01-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge on the structure, function, metabolism and regulation of HDL in health and several diseases as well as the status of past and ongoing attempts of therapeutic exploitation. The book is of interest to researchers in academia and industry focusing on lipoprotein metabolism, cardiovascular diseases and immunology as well as clinical pharmacologists, cardiologists, diabetologists, nephrologists and other clinicians interested in metabolic or inflammatory diseases.