Chiral Separations And Stereochemical Elucidation

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Chiral Separations and Stereochemical Elucidation

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Author : Quezia Bezerra Cass
Publisher : John Wiley & Sons
ISBN 13 : 1119802253
Total Pages : 644 pages
Book Rating : 4.1/5 (198 download)

Book Synopsis Chiral Separations and Stereochemical Elucidation by : Quezia Bezerra Cass

Download or read book Chiral Separations and Stereochemical Elucidation written by Quezia Bezerra Cass and published by John Wiley & Sons. This book was released on 2023-05-09 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: An expert resource for chemists using stereochemical analysis methods In Chiral Separations and Stereochemical Elucidation: Fundamentals, Methods, and Applications, a team of distinguished researchers delivers a robust and authoritative discussion of the theoretical fundamentals of chiral separation, the most commonly used chiral selectors, and stereochemical elucidation methods. The book offers expert discussions of a variety of chiral separation methods by gas chromatography (GC), supercritical fluid chromatography (SFC), capillary electrophoresis (CE), and liquid chromatography (LC). The authors also describe several methods for stereochemical elucidation, including X-ray crystallography, nuclear magnetic resonance spectroscopy, and chiroptical methods. The explored material is ideal for practicing chemists seeking a resource to help them guide method development and optimization or to explain quality control-complements during target compound production. Readers will also find: A thorough introduction to the most important advances and applications in LC, GC, CE, SFC, and preparative chromatography Comprehensive explorations of the role of 2D-LC for chiral separation methods development and applications Practical discussions of the design, mechanisms, and applications of the most commonly used chiral selectors Fulsome treatments of the theoretical backgrounds, advantages, limitations, and applications of stereochemical elucidation methods Perfect for academic and industrial chemists specially in organic, analytical chemistry and pharmaceutical analysis. Chiral Separations and Stereochemical Elucidation: Fundamentals, Methods, and Applications will also benefit biochemists, environmental analysts, forensic and medicinal chemists as well as natural product chemists and those involved with stereochemistry or structural elucidation.

Chiral Separation Techniques

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Author : G. Subramanian
Publisher : Wiley-VCH
ISBN 13 :
Total Pages : 376 pages
Book Rating : 4.3/5 (91 download)

Book Synopsis Chiral Separation Techniques by : G. Subramanian

Download or read book Chiral Separation Techniques written by G. Subramanian and published by Wiley-VCH. This book was released on 2001 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a completely revised and updated sequel to 'A Practical Approach to Chiral Separations by Liquid Chromatography' by the same editor. The scope has been extended to further chiral separation techniques like electrophoresis, membrane separations, or biological assays. More emphasis is put on preparative separation techniques. From reviews of the previous edition: 'A team of experts from academic and industrial laboratories throughout the world have compiled their findings and experience to make this book an exceptionally timely and unique contribution to the field' European Journal of Drug Metabolism 'The dense mass of information contained in this book will make it a valuable resource ...' Chemical Engineering Research '... this is a worthwhile addition to the expanding chiral literature and the book should be of value to those working in this field' The Analyst

Chiral Separations

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Author : D. Stevenson
Publisher : Springer Science & Business Media
ISBN 13 : 1461566347
Total Pages : 203 pages
Book Rating : 4.4/5 (615 download)

Book Synopsis Chiral Separations by : D. Stevenson

Download or read book Chiral Separations written by D. Stevenson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents the proceedings of a two-day international meeting on chiral chromatography held at the University of Surrey between 3-4 September 1987. The meeting was jointly organized by the Chromatographic SOCiety and the Robens Institute of the University of Surrey in response to the burgeoning interest in this rapid maturing field of chromatography. Nowhere is this interest more evident than in the agrochemical and pharmaceutical industries where the implications of different pharmacological and toxicological activity for the individual enantiomers present in a racemic drug ol" insecticide is an increasing area of concern. Developments in the area of chiral separations are at last beginning to provide SCientists with the necessary tools to study how animals and man handle racemates and relate their obseIVations to the obseIVed biological effects of these substances. The development of robust and Simple methods for the separation of enantiomers will therefore have a profound Impact on safety evaluation and drug design. The meeting proved to be very successful. with over 160 delegates from thirteen countries in Europe and America present to learn from the experiences of experts in the field of chiral chromatography and to hear about the latest developments. Hopefully. in future symposia on chiral separations at the University of Surrey.

Chiral Separation Techniques

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Author : Ganapathy Subramanian
Publisher : Wiley-VCH
ISBN 13 : 9783527600366
Total Pages : 368 pages
Book Rating : 4.6/5 (3 download)

Book Synopsis Chiral Separation Techniques by : Ganapathy Subramanian

Download or read book Chiral Separation Techniques written by Ganapathy Subramanian and published by Wiley-VCH. This book was released on 2001-10-18 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a completely revised and updated sequel to 'A Practical Approach to Chiral Separations by Liquid Chromatography' by the same editor. The scope has been extended to further chiral separation techniques like electrophoresis, membrane separations, or biological assays. More emphasis is put on preparative separation techniques. From reviews of the previous edition: 'A team of experts from academic and industrial laboratories throughout the world have compiled their findings and experience to make this book an exceptionally timely and unique contribution to the field' European Journal of Drug Metabolism 'The dense mass of information contained in this book will make it a valuable resource ...' Chemical Engineering Research '... this is a worthwhile addition to the expanding chiral literature and the book should be of value to those working in this field' The Analyst

Stereochemistry of Organic Compounds

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Author : Ernest L. Eliel
Publisher : John Wiley & Sons
ISBN 13 : 0471016705
Total Pages : 1296 pages
Book Rating : 4.4/5 (71 download)

Book Synopsis Stereochemistry of Organic Compounds by : Ernest L. Eliel

Download or read book Stereochemistry of Organic Compounds written by Ernest L. Eliel and published by John Wiley & Sons. This book was released on 1994-09-28 with total page 1296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereochemistry of Organic Compounds The first fully referenced, comprehensive book on this subject in more than thirty years, Stereochemistry of Organic Compounds contains up-to-date coverage and insightful exposition of all important new concepts, developments, and tools in the rapidly advancing field of stereochemistry, including: * Asymmetric and diastereoselective synthesis * Conformational analysis * Properties of enantiomers and racemates * Separation and analysis of enantiomers and diastereoisomers * Developments in spectroscopy (including NMR), chromatography, and molecular mechanics as applied to stereochemistry * Prostereoisomerism * Conceptual foundations of stereochemistry, including terminology and symmetry concepts * Chiroptical properties Written by the leading authorities in the field, the text includes more than 4,000 references, 1,000 illustrations, and a glossary of stereochemical terms.

Chromatographic Chiral Separations

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Author : Morris Zief
Publisher : CRC Press
ISBN 13 : 9780824777869
Total Pages : 432 pages
Book Rating : 4.7/5 (778 download)

Book Synopsis Chromatographic Chiral Separations by : Morris Zief

Download or read book Chromatographic Chiral Separations written by Morris Zief and published by CRC Press. This book was released on 1987-10-02 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chiral Recognition in Separation Methods

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Author : Alain Berthod
Publisher : Springer Science & Business Media
ISBN 13 : 3642124453
Total Pages : 349 pages
Book Rating : 4.6/5 (421 download)

Book Synopsis Chiral Recognition in Separation Methods by : Alain Berthod

Download or read book Chiral Recognition in Separation Methods written by Alain Berthod and published by Springer Science & Business Media. This book was released on 2010-06-16 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: What drives a scientist to edit a book on a speci c scienti c subject such as chiral mechanisms in separation methods? Until December 2005, the journal Analytical Chemistry of the American Chemical Society (Washington, DC) had an A-page section that was dedicated to simple and clear presentations of the most recent te- niques or the state of the art in a particular eld or topic. The “A-page” section was prepared for a broad audience of chemists including industrial professionals, s- dents as well as academics looking for information outside their eld of expertise. 1 Daniel W. Armstrong, one of the editors of this journal and a twenty-year+ long friend, invited me to present my view on chiral recognition mechanisms in a simple and clear way in an “A-page” article. In 2006, the “A-page” section was maintained as the rst articles at the beginning of each rst bi-monthly issue but the pagination was no longer page distinguished from the regular research articles published by the journal. During the time between the invitation and the submission, the A-page section was integrated into the rest of the journal and the article appeared as (2006) Anal Chem (78):2093–2099.

Chiral Separations by Liquid Chromatography

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Author :
Publisher :
ISBN 13 :
Total Pages : 239 pages
Book Rating : 4.:/5 (641 download)

Book Synopsis Chiral Separations by Liquid Chromatography by :

Download or read book Chiral Separations by Liquid Chromatography written by and published by . This book was released on 1991 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Recent Advances in Chiral Separations

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Author : D. Stevenson
Publisher :
ISBN 13 : 9781468482836
Total Pages : 244 pages
Book Rating : 4.4/5 (828 download)

Book Synopsis Recent Advances in Chiral Separations by : D. Stevenson

Download or read book Recent Advances in Chiral Separations written by D. Stevenson and published by . This book was released on 1991-03-31 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chiral Separation Methods for Pharmaceutical and Biotechnological Products

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Author : Satinder Ahuja
Publisher : John Wiley & Sons
ISBN 13 : 1118097750
Total Pages : 474 pages
Book Rating : 4.1/5 (18 download)

Book Synopsis Chiral Separation Methods for Pharmaceutical and Biotechnological Products by : Satinder Ahuja

Download or read book Chiral Separation Methods for Pharmaceutical and Biotechnological Products written by Satinder Ahuja and published by John Wiley & Sons. This book was released on 2011-03-31 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses chiral separations and offers guidance for selecting the optimum method for desired results Chiral separations represent the most intriguing and, by some measures, most difficultseparations of chemical compounds. This book provides researchers and students an under-standing of chiral separations and offers a convenient route to selecting the best separation method, saving considerable time and cost in product development. Considering chiral separations in the biotechnological and pharmaceutical industries, as well as for food applications, Dr. Ahuja provides insights into a broad range of topics. Opening with a broad overview of chiral separations, regulatory considerations in drug product development, and basic issues in method development, the book: Covers a variety of modern methods such as gas chromatography, high performance liquid chromatography, supercritical fluid chromatography, and capillary electrophoresis Deals with the impact of chirality on the biological activity of small and large molecules Provides detailed information on useful chiral stationary phases (CSPs) for HPLC Includes handy information on selection of an appropriate CSP, including mechanistic studies Offers strategies for fast method development with HPLC, SFC, and CE Discusses preparatory methods utilized in the pharmaceutical industry With in-depth discussions of the current state of the field as well as suggestions to assist future developments, Chiral Separation Methods for Pharmaceutical and Biotechnological Products is an essential text for laboratory investigators, managers, and regulators who are involved in chiral separations in the pharmaceutical industry, as well as students preparing for careers in these fields.

Stereochemistry

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Author : Anil V. Karnik
Publisher : Elsevier
ISBN 13 : 012821063X
Total Pages : 622 pages
Book Rating : 4.1/5 (282 download)

Book Synopsis Stereochemistry by : Anil V. Karnik

Download or read book Stereochemistry written by Anil V. Karnik and published by Elsevier. This book was released on 2021-07-21 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereochemistry: A Three-Dimensional Insight draws on the knowledge of its expert authors, providing a systematic treatment on the fundamental aspects of stereochemistry, covering conformational aspects, configurational aspects, effects of bulkiness, stereoelectronic effects on properties of molecules, and the genesis of enantiomerism, among other topics. Visuals and exercises are included to consolidate the principles learned, and the contents are carefully structured to prepare readers for predicting and organizing reaction components to obtain desired stereochemical outcomes. This book is an indispensable guide for all those exploring stereochemistry within their work. The principles of stereochemistry are fundamental to understanding chemical behavior and can provide insights into a whole range of problems, from unusual selectivity and unexpected behaviors, to abnormally fast reactions and surprising biochemical preferences. However, understanding and exploring these 3D effects can be difficult within a 2D medium. This book has been designed to address this problem, providing foundational guidance on the principles and applications of stereochemistry that are fully supported by multimedia visuals. Combines foundational concepts and definitions with examples of stereochemistry in practice Highlights the conformational and configurational impact of atomic arrangement on chemical behavior Outlines methods of analysis Provides practical exercises and detailed multimedia visuals to support learning

Dynamic Stereochemistry of Chiral Compounds

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Author : Christian Wolf
Publisher : Royal Society of Chemistry
ISBN 13 : 0854042466
Total Pages : 534 pages
Book Rating : 4.8/5 (54 download)

Book Synopsis Dynamic Stereochemistry of Chiral Compounds by : Christian Wolf

Download or read book Dynamic Stereochemistry of Chiral Compounds written by Christian Wolf and published by Royal Society of Chemistry. This book was released on 2008 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview of fundamental concepts of asymmetric synthesis along with in-depth discussion. Recent developments that address important synthetic challenges are presented and highlighted with hundreds of examples.

Chiral Separations

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Author : Derek Stevenson
Publisher : Springer
ISBN 13 : 9781461566359
Total Pages : 206 pages
Book Rating : 4.5/5 (663 download)

Book Synopsis Chiral Separations by : Derek Stevenson

Download or read book Chiral Separations written by Derek Stevenson and published by Springer. This book was released on 2012-12-22 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents the proceedings of a two-day international meeting on chiral chromatography held at the University of Surrey between 3-4 September 1987. The meeting was jointly organized by the Chromatographic SOCiety and the Robens Institute of the University of Surrey in response to the burgeoning interest in this rapid maturing field of chromatography. Nowhere is this interest more evident than in the agrochemical and pharmaceutical industries where the implications of different pharmacological and toxicological activity for the individual enantiomers present in a racemic drug ol" insecticide is an increasing area of concern. Developments in the area of chiral separations are at last beginning to provide SCientists with the necessary tools to study how animals and man handle racemates and relate their obseIVations to the obseIVed biological effects of these substances. The development of robust and Simple methods for the separation of enantiomers will therefore have a profound Impact on safety evaluation and drug design. The meeting proved to be very successful. with over 160 delegates from thirteen countries in Europe and America present to learn from the experiences of experts in the field of chiral chromatography and to hear about the latest developments. Hopefully. in future symposia on chiral separations at the University of Surrey.

Enantioselective Synthesis, Enantiomeric Separations and Chiral Recognition

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Author : Maria Elizabeth Tiritan
Publisher : MDPI
ISBN 13 : 3039362380
Total Pages : 346 pages
Book Rating : 4.0/5 (393 download)

Book Synopsis Enantioselective Synthesis, Enantiomeric Separations and Chiral Recognition by : Maria Elizabeth Tiritan

Download or read book Enantioselective Synthesis, Enantiomeric Separations and Chiral Recognition written by Maria Elizabeth Tiritan and published by MDPI. This book was released on 2020-11-13 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book includes both fundamental studies and applications in a multidisciplinary research field involving a high diversity of chiral compounds, including commercial substances with industrial applications, pharmaceuticals, and new chiral compounds with promising biological activities.

The Practice of Enantiomer Separation by Capillary Gas Chromatography

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Author : Wilfried A. König
Publisher :
ISBN 13 :
Total Pages : 128 pages
Book Rating : 4.3/5 (91 download)

Book Synopsis The Practice of Enantiomer Separation by Capillary Gas Chromatography by : Wilfried A. König

Download or read book The Practice of Enantiomer Separation by Capillary Gas Chromatography written by Wilfried A. König and published by . This book was released on 1987 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chiral Separations

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Author : Satinder Ahuja
Publisher :
ISBN 13 :
Total Pages : 376 pages
Book Rating : 4.3/5 (91 download)

Book Synopsis Chiral Separations by : Satinder Ahuja

Download or read book Chiral Separations written by Satinder Ahuja and published by . This book was released on 1997 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Asymmetric synthesis resolution, the basic approaches to obtaining chiral compounds, are discussed in a variety of innovative contexts, including enantioselective reactions and additions, enzyme-catalyzed reactions, chromatographic methods with various chiral stationary phases or chiral discriminators, and enantioselective membrane transport.

Chiral Separations Using B-cyclodextrin with Capillary Zone Electrophoresis

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Author : William Lowery Duncan (Jr.)
Publisher :
ISBN 13 :
Total Pages : 29 pages
Book Rating : 4.:/5 (65 download)

Book Synopsis Chiral Separations Using B-cyclodextrin with Capillary Zone Electrophoresis by : William Lowery Duncan (Jr.)

Download or read book Chiral Separations Using B-cyclodextrin with Capillary Zone Electrophoresis written by William Lowery Duncan (Jr.) and published by . This book was released on 1993 with total page 29 pages. Available in PDF, EPUB and Kindle. Book excerpt: