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Author : Chung-Yih Wang
Publisher :
ISBN 13 :
Total Pages : 366 pages
Book Rating : 4.3/5 (91 download)
Download or read book Characterization of a Novel Ets Transcription Factor, Elf-1 written by Chung-Yih Wang and published by . This book was released on 1993 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kyungmin Benjamin Hahm
Publisher :
ISBN 13 :
Total Pages : 382 pages
Book Rating : 4.:/5 ( download)
Download or read book Characterization of Transcription Factor LyF-1/Ikaros written by Kyungmin Benjamin Hahm and published by . This book was released on 1997 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Tao Liang
Publisher :
ISBN 13 :
Total Pages : 290 pages
Book Rating : 4.:/5 (16 download)
Download or read book Characterization of a Novel Transcription Factor written by Tao Liang and published by . This book was released on 1995 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : M.E. Gershwin
Publisher : Elsevier
ISBN 13 : 0080528457
Total Pages : 467 pages
Book Rating : 4.0/5 (85 download)
Download or read book Cancer and Autoimmunity written by M.E. Gershwin and published by Elsevier. This book was released on 2000-03-27 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of the two disciplines in parallel development for two decades, tumor immunology and transplantation immunology, the latter has thrived and has led to some of the most critical discoveries in immunobiology. The former continues to thwart both scientists and clinicians alike.The goal of immunologists in modern day research is to develop a simple and effective means to manipulate cancer in vivo, possibly encompassing several venues: identifying a phenotypic marker and the use of either active or passive immunization; include the use of passive reagents carrying "warheads" to selectively destroy cancer cells; or altering the basic process of cell survival.This excellent multidiscipline-authored volume presents a theme which has not been well described before. The papers include both basic and clinical science and range from sophisticated molecular biology to little more than phenomenology (e.g. the increased association of cancer in some autoimmune diseases and increased presentation of autoimmune phenomena in malignant condition). This, however, is state-of-the-art.This collection of themes will be of use not only to bench scientists, but also to clinicians who treat patients. The book represents progress at the cutting edge of this discipline, and points the way to further developments in the "black box" of immunology.
Author :
Publisher :
ISBN 13 :
Total Pages : 176 pages
Book Rating : 4.:/5 (327 download)
Download or read book AIDS Bibliography written by and published by . This book was released on 1995-04 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Katya Ravid
Publisher : John Wiley & Sons
ISBN 13 : 0471461067
Total Pages : 640 pages
Book Rating : 4.4/5 (714 download)
Download or read book Transcription Factors written by Katya Ravid and published by John Wiley & Sons. This book was released on 2003-11-04 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transcription Factors Normal and Malignant Development of Blood Cells Katya Ravid and Jonathan Licht The role of transcription factors in activating specific genes in blood cells is an important facet of hematopoiesis. Equally important, however, is the pursuit of genes rearranged and aberrantly activated in leukemias (blood malignancies). Transcription Factors: Normal and Malignant Development of Blood Cells focuses on those major transcription factors involved in activation of lineage-specific gene expression during normal versus malignant development of specific blood lineages, as revealed from gene promoter studies, knockout of transcription factors in mice models, and the identification and characterization of chromosomal rearrangement in human blood leukemias. This complete digest of current transcription factor data offers comprehensive coverage of the myriad of transcription factors in blood cell development, composed by established experts in the field. In addition to updating the reader on the connection between chromosomal translocations involving transcription factors and cellular transformation leading to leukemia, Transcription Factors also reviews such subjects as: * Transcription factors and the megakaryocytic, myeloid, and erythroid lineages * Leukemias due to chromosomal translocations involving gene encoding transcription factors * Oncogenesis and hematopoiesis * In vivo studies of transcription factors implicated in hematopoiesis * And much more Appealing to both the researcher and the clinician in the field of hematology, Transcription Factors is a timely presentation of cell lineage development and sheds light on the processes involved in the development of specific leukemias. Providing insight into the study of transcription factors, readers will gain an understanding of mechanisms that lead to normal lineage commitment and terminal differentiation.
Author : Moshe Yaniv
Publisher : Springer Science & Business Media
ISBN 13 : 9783764354862
Total Pages : 276 pages
Book Rating : 4.3/5 (548 download)
Download or read book Oncogenes as Transcriptional Regulators written by Moshe Yaniv and published by Springer Science & Business Media. This book was released on 1997 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1 Myc Structure and Function.- 2 The ETS Family of Transcriptional Regulators.- 3 myb Proto-Oncogene Product as a Transcriptional Regulator.- 4 The v-erbA Oncogene.- 5 Rel Proteins and Their Inhibitors: A Balancing Act.- 6 Structure/Function and Oncogenic Conversion of Fos and Jun.
Author :
Publisher :
ISBN 13 :
Total Pages : 1764 pages
Book Rating : 4.3/5 (243 download)
Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1764 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : P.A. Baeuerle
Publisher : Springer Science & Business Media
ISBN 13 : 1468468405
Total Pages : 294 pages
Book Rating : 4.4/5 (684 download)
Download or read book Inducible Gene Expression, Volume 1 written by P.A. Baeuerle and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells have evolved multiple strategies to adapt the composition and quality of their protein equipment to needs imposed by changes in intra- and extracellular conditions. The appearance of pro teins transmit ting novel functional properties to cells can be controlled at a transcrip tional, posttranscriptional, translational or posttranslational level. Extensive research over the past 15 years has shown that transcriptional regulation is used as the predominant strategy to control the production of new proteins in response to extracellular stimuli. At the level of gene transcription, the initiation ofmRNA synthesis is used most frequently to govern gene expression. The key elements controlling transcription initiation in eukaryotes are activator proteins (transactivators) that bind in a sequence-specific manner to short DNA sequences in the of genes. The activator binding sites are elements of larger proximity control units, ca lied promoters and enhancers, which bind many distinct proteins. These may synergize or negatively cooperate with the activators. The do novo binding of an activator to DNA or, if already bound to DNA, its functional activation is what ultimately turns on a high-level expression of genes. The activity of transactivators is controlled by signalling pathways and, in some cases, transactivators actively partici pate in signal transduction by moving from the cytoplasm into the nuc1eus. In this first volume of Inducible Gene Expression, leading scientists in the field review six eukaryotic transactivators that allow cells to respond to various extracellular stimuli by the expression of new proteins.
Author :
Publisher :
ISBN 13 :
Total Pages : 846 pages
Book Rating : 4.F/5 ( download)
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2000 with total page 846 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : John A. Mol
Publisher : Springer Science & Business Media
ISBN 13 : 0306468328
Total Pages : 309 pages
Book Rating : 4.3/5 (64 download)
Download or read book Biology of the Mammary Gland written by John A. Mol and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the European Cooperation in the Field of Scientific and Technical Research (COST 825) Symposium on Mammary Gland Biology, held September 16-18, 1999, in Tours, France. It is difficult to overstate the evolutionary and functional significance of mammary tissue in biology. Substantial progress has been made by researchers in various disciplines, particularly over the last fifteen years, towards realizing the potential of this tissue to yield powerful experimental models for morphogenesis and tissue development; for cellular differentiation; for the biosynthesis and secretion of proteins, lipids, small molecules and inorganic salts; and for the coordination and regulation of these processes. More recently, the possibility of exploiting the secretory epithelial cells of mammary tissue as `cell factories' has become a reality and the recombinant production by lactating animals of an increasing number of proteins, valuable both in the pharmaceutical and `nutraceutical' fields, is in progress or under development. Also in this sphere of agricultural production, genetic as well as nutritional technologies are under investigation and exploitation to optimize milk composition for various end-uses - for instance in food process and manufacture. The possibilities of deriving health benefit from the bioactive properties of some of the minor constituents of milk are emerging to counter the highly-publicized negative health impact of excessive consumption of saturated animal fats. In human nutrition and medicine, the mammary gland is both a source of nutrition to the neonate and a potential health threat to the adult female - breast cancer remains the major single cause of female mortality in most developed countries. This volume provides a unique glimpse into our understanding, at the cutting edge of a variety of disciplines, of this versatile and extraordinary tissue, at the birth of the twenty-first century.
Author : David Abraham
Publisher : Springer Science & Business Media
ISBN 13 : 184628919X
Total Pages : 256 pages
Book Rating : 4.8/5 (462 download)
Download or read book Vascular Complications in Human Disease written by David Abraham and published by Springer Science & Business Media. This book was released on 2008-10-14 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, there have been several major advances in our understanding of the causes of diseases affecting the heart, lungs, kidneys, skin and blood vessels. This book offers a concise and carefully composed collection of reviews on vascular biology. Each chapter is written by an internationally respected authority in the field and is a state of the art review of important parts of basic and clinical science.
Author :
Publisher :
ISBN 13 :
Total Pages : 1180 pages
Book Rating : 4.:/5 ( download)
Download or read book Anticancer Research written by and published by . This book was released on 2003 with total page 1180 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (793 download)
Download or read book Tumors of the Central Nervous System written by and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 448 pages
Book Rating : 4.X/5 (6 download)
Download or read book Nucleic Acids Abstracts written by and published by . This book was released on 1997 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 1810 pages
Book Rating : 4.:/5 (319 download)
Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 1810 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Author : Daniel J. Wallace
Publisher : Oxford University Press
ISBN 13 : 0190876220
Total Pages : 364 pages
Book Rating : 4.1/5 (98 download)
Download or read book The Lupus Book written by Daniel J. Wallace and published by Oxford University Press. This book was released on 2019-02-01 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lupus, a disease of the immune system, can be quite deadly, claiming the lives of thousands of patients yearly. Dr. Daniel J. Wallace is one of the world's leading authorities on this disorder, an eminent clinician who has treated over 3,000 lupus patients, the largest such practice in America. His The Lupus Book, originally published in 1995, immediately established itself as the most readable and helpful book on the disease. Now Dr. Wallace has once again completely revised The Lupus Book, incorporating a wealth of new information. This Sixth Edition discusses new drug information and newly discovered information about the pathology of the diseaseâall laid out in user-friendly language that any patient could understand. In particular, Wallace discusses the first drug for lupus to be approved by the FDA--belimumab (Benlysta)--as well as other drugs in clinical trials. Readers will also discover fully updated sections on the science of lupus and breakthroughs in research including: genetics, microbiome, and clinical trial methodology. And as in past editions, the book provides absolutely lucid answers to such questions as: What causes lupus? How and where is the body affected? Can a woman with lupus have a baby? And how can one manage this disease? Indeed, Dr. Wallace has distilled his extensive experience, providing the most up-to-date information on causes, prevention, cure, exercise, diet, and many other important topics. There is also a glossary of terms and an appendix of lupus resource materials compiled by Dr. Wallace. Over 1.5 million Americans have lupus. The new Sixth Edition offers these patients and their families an abundance of reliable, information that will help them manage the disease and live a happier life.
