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Chalcogenopyrylium Dyes
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Book Synopsis Tellurium-Containing Heterocycles, Volume 53 by : Michael R. Detty
Download or read book Tellurium-Containing Heterocycles, Volume 53 written by Michael R. Detty and published by John Wiley & Sons. This book was released on 2009-09-17 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.
Book Synopsis Chalcogenopyrylium Dyes by : Peter R. Virkler
Download or read book Chalcogenopyrylium Dyes written by Peter R. Virkler and published by . This book was released on 2001 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Chalcogenopyrylium Dyes with Anchors to Nanoparticle and Semiconductor Surfaces by : Matthew Allen Bedics
Download or read book Chalcogenopyrylium Dyes with Anchors to Nanoparticle and Semiconductor Surfaces written by Matthew Allen Bedics and published by . This book was released on 2015 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface enhanced Raman scattering (SERS) has gained widespread attention as a biomedical imaging technique due to its multiplexing capabilities and the low limits of detection (LODs) of SERS-nanoprobes. The library of available reporter molecules, which are used to generate unique SERS spectra, was previously limited to commercially available dyes or a small group of cyanine reporters. Herein, the design and synthesis of a novel group of chalcogenopyrylium SERS reporters is described. These dyes have a high affinity for Au and absorption maxima that range into the NIR region. These reporter molecules enabled the use of the 1280 nm laser, which was previously incompatible with SERS imaging. Also, nanoprobe LODs using these dyes as reporters are lower than any previously documented systems, with a 100 aM LOD using a 785 nm excitation and multiple examples of fM to pM LODs using a 1064 nm or 1280 nm excitation source. Nanoprobes functionalized with these compounds have also been successfully utilized in vivo, and produce more intense SERS spectra as compared to a commonly used cyanine reporter. Dye sensitized solar cells (DSSCs) have produced considerable interest as an alternative to conventionally used Si-based solar cells. Specifically, DSSCs that use metal-free organic dyes as sensitizers are important due to the lower cost and the use of earth abundant materials as starting materials. Herein, a group of chalcogenopyrylium dyes were appended with an anchoring group to TiO2, which enables the use of these dyes as sensitizers. Structural modifications were used to extend absorption maxima into the near-infrared region of the light spectrum and to evaluate the effect that dye aggregation has on device performance. The monomethine dyes successfully produced a photocurrent, with incident photon to current efficiency values as high as 20%. Aggregation was found to benefit these systems due to the spectral broadening of aggregated dyes, and consequent increased range of wavelengths that produce a photocurrent.
Book Synopsis Advances in Heterocyclic Chemistry by :
Download or read book Advances in Heterocyclic Chemistry written by and published by Academic Press. This book was released on 1994-10-05 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area-one of great importance to organic chemists, polymer chemists, and most biological scientists. Volume 60 contains a cumulative subject index covering Volumes 55 through 60.
Book Synopsis Synthesis of Novel Chalcogenopyrylium Dyes for Dye-sensitised Solar Cells by : Chi Wing Szeto
Download or read book Synthesis of Novel Chalcogenopyrylium Dyes for Dye-sensitised Solar Cells written by Chi Wing Szeto and published by . This book was released on 2015 with total page 45 pages. Available in PDF, EPUB and Kindle. Book excerpt: Novel chalcogenopyrylium dyes for dye-sensitized solar cells were synthesized, including monomethine dyes with different chalcogenopyrylium cores, dyes with phosphonate or symmetrical carboxylic acid anchoring groups, and dyes with electron-donating triphenylamine and N, N-dimethylphenylamine moieties. The synthetic strategy for chalcogenopyrylium dyes is to generate the key chalcogenopyranone intermediate initially, followed by condensation with 4-methylpyrylium dyes. The reactive anchoring carboxylic acid group was protected in the synthesis by an ethyl ester and the deprotection method of these dyes is developed in this thesis.
Book Synopsis Chemistry of Heterocyclic Compounds by : Michael R. Detty
Download or read book Chemistry of Heterocyclic Compounds written by Michael R. Detty and published by . This book was released on 1950 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Design and Synthesis of Novel Chalcogenopyrylium Dyes as Agents for Photodynamic Therapy by : Kristi Anne Leonard
Download or read book The Design and Synthesis of Novel Chalcogenopyrylium Dyes as Agents for Photodynamic Therapy written by Kristi Anne Leonard and published by . This book was released on 2000 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Design and Synthesis of Novel Chalcogenopyrylium Dyes for Use as Therapeutic Sensitizers in Photodynamic Therapy by : Nancy Kristin Brennan
Download or read book The Design and Synthesis of Novel Chalcogenopyrylium Dyes for Use as Therapeutic Sensitizers in Photodynamic Therapy written by Nancy Kristin Brennan and published by . This book was released on 2002 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advances in Physical Organic Chemistry by :
Download or read book Advances in Physical Organic Chemistry written by and published by Elsevier. This book was released on 2004-10-06 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Physical Organic Chemistry provides the chemical community with authoritative and critical assessments of the many aspects of physical organic chemistry. The field is a rapidly developing one, with results and methodologies finding application from biology to solid state physics.
Book Synopsis Next Generation Point-of-care Biomedical Sensors Technologies for Cancer Diagnosis by : Pranjal Chandra
Download or read book Next Generation Point-of-care Biomedical Sensors Technologies for Cancer Diagnosis written by Pranjal Chandra and published by Springer. This book was released on 2017-12-30 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents recent research on cancer detection methods based on nanobiosensors, which offer ultrasensitive point-of-care diagnosis. Several methods for diagnosing cancer have been discovered and many more are currently being developed. Conventional clinical approaches to detecting cancers are based on a biopsy followed by histopathology, or on the use of biomarkers (protein levels or nucleic acid content). Biopsy is the most widely used technique; however, it is an invasive technique and is not always applicable. Furthermore, biomarker-based detection cannot be relied on when the biomarkers are present in an extremely low concentration in the body fluids and in malignant tissues. Thus, in recent years highly sensitive and robust new cancer diagnosis techniques have been developed for clinical application, and may offer an alternative strategy for cancer diagnosis. As such, this book gathers the latest point-of-care cancer diagnostic methods and protocols based on biomedical sensors, microfluidics, and integrated systems engineering. It also discusses recent developments and diagnostics tests that can be conducted outside the laboratory in remote areas. These technologies include electrochemical sensors, paper-based microfluidics, and other kit-based diagnostic methods that can be adapted to bring cancer detection and diagnostics to more remote settings around the globe. Overall, the book provides students, researchers, and clinicians alike a comprehensive overview of interdisciplinary approaches to cancer diagnosis.
Book Synopsis Organic Reaction Mechanisms 1998 by : A. C. Knipe
Download or read book Organic Reaction Mechanisms 1998 written by A. C. Knipe and published by John Wiley & Sons. This book was released on 2003-09-12 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: 34th volume in this highly successful series, Organic Reaction Mechanisms Provides the most recent developments in organic chemistry Compiled by well-respected editors with many years of relevant experience
Book Synopsis Photosensitisers in Biomedicine by : Mark Wainwright
Download or read book Photosensitisers in Biomedicine written by Mark Wainwright and published by John Wiley & Sons. This book was released on 2009-03-25 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Photosensitisers in Biomedicine offers clear and comprehensive coverage of the many different photosensitiser types, including information on their many applications that now extend beyond anticancer therapy. These applications now include photoantimicrobial treatments not only in microbial disease, but also in the microbial resistance to conventional drugs, which is circumvented by photomicrobial action. The application of photoantimicrobials in biological fluids is also of considerable importance in the current era of HIV and is discussed in the book. This text offers the most up-to-date coverage of photodynamic therapy including information on how photosensitisers have evolved within the field of cancer therapy and more recently antimicrobial research. There are few books on the market that take the approach of this text, as many are either conference based or focus on the chemistry of photosensitisers. Photosensitisers in Biomedicine is clearly defined into three distinct parts beginning with a clear introduction to the various types of photosensitisers. The book then moves on to discuss the chemistry of photosensitisers and closes with their numerous applications, for example, photodynamic therapy, photodiagnosis, photodynamic antimicrobial chemotherapy (PACT) and other non-oncological applications such as optical, arterial plaques and stents.
Download or read book Hybrid Nanomaterials written by Weibo Cai and published by CRC Press. This book was released on 2017-05-25 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, an unprecedented expansion in the field of nanomedicine has resulted in the development of new nanomaterials for diagnosis and therapy of various diseases such as cancer. This book covers the design, synthesis and applications of various functionally-hybridized nanomaterials for biomedical applications. It includes strategies for design and synthesis of hybrid nanomaterials, surface engineering of various nanoparticle-based hybrid nanosystems for cancer imaging and therapy, toxicity aspects of nanomaterials and the challenges in translation research of hybrid nanomaterials.
Book Synopsis Surface-Enhanced Raman Spectroscopy by : Marek Prochazka
Download or read book Surface-Enhanced Raman Spectroscopy written by Marek Prochazka and published by Springer. This book was released on 2015-12-12 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an overview of recent developments in RS and SERS for sensing and biosensing considering also limitations, possibilities and prospects of this technique. Raman scattering (RS) is a widely used vibrational technique providing highly specific molecular spectral patterns. A severe limitation for the application of this spectroscopic technique lies in the low cross section of RS. Surface-enhanced Raman scattering (SERS) spectroscopy overcomes this problem by 6-11 orders of magnitude enhancement compared with the standard RS for molecules in the close vicinity of certain rough metal surfaces. Thus, SERS combines molecular fingerprint specificity with potential single-molecule sensitivity. Due to the recent development of new SERS-active substrates, labeling and derivatization chemistry as well as new instrumentations, SERS became a very promising tool for many varied applications, including bioanalytical studies and sensing. Both intrinsic and extrinsic SERS biosensing schemes have been employed to detect and identify small molecules, nucleic acids and proteins, and also for cellular and in vivo sensing.
Book Synopsis Smart Nanodevices for Point-of-Care Applications by : Suvardhan Kanchi
Download or read book Smart Nanodevices for Point-of-Care Applications written by Suvardhan Kanchi and published by CRC Press. This book was released on 2022-06-23 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smart Nanodevices for Point-of-Care Applications examines the latest trends on the capabilities of nanomaterials for point-of-care (PoC) diagnostics and explains how these materials can help to strengthen, miniaturize, and improve the quality of diagnostic devices. A thorough explanation of all-in-one nanosmart devices is included, incorporating all of the applications and fundamentals of these smart devices. This book provides practical information on the following: novel and effective smart materials, better-quality health management, effective management of a disease, potential point-of-care devices, and mobile nanosensors. Additional Features Includes in-depth research based collation of the latest trends of smart devices Provides practical information on all-in-one nanosmart devices Explains how nanomaterials can help to strengthen and improve the quality of diagnostic devices Emphasizes the development of smart nanodevices, especially the miniaturization aspect
Author :Tadeusz Marek Krygowski Publisher :Springer Science & Business Media ISBN 13 :3540683291 Total Pages :355 pages Book Rating :4.5/5 (46 download)
Book Synopsis Aromaticity in Heterocyclic Compounds by : Tadeusz Marek Krygowski
Download or read book Aromaticity in Heterocyclic Compounds written by Tadeusz Marek Krygowski and published by Springer Science & Business Media. This book was released on 2009-01-30 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterocyclic chemistry is the biggest branch of chemistry covering two-thirds of the chemical literature. Aromaticity in Heterocyclic Compounds covers hot topics of frontier research summarized by reputed scientists in the field.
Book Synopsis Novel Chalcogenopyrylium Dyes as Modulators of ATP-binding Cassette Transporters℗ by : Sean Philip Ebert
Download or read book Novel Chalcogenopyrylium Dyes as Modulators of ATP-binding Cassette Transporters℗ written by Sean Philip Ebert and published by . This book was released on 2012 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Detty group has made recent advances in the area of P-glycoprotein (P-gp) inhibition. After receiving promising results regarding the effect of amide/thioamide chalcogenorhodamine dyes on P-gp activity, a library of chalcogenopyrylium amide/thioamide dyes was synthesized to probe their effect on P-gp inhibition and transport. The thiopyrylium compounds underwent studies by the University of Toronto and Eli Lilly for stimulation, inhibition, and transport. Furthermore, this very set of dyes was also tested by Queens University for activity regarding Multidrug Resistance-associated Protein 1 (MRP1). The synthesis of this particular set of dyes and their results are described throughout. The synthesis of the thiopyrylium dyes involved varying substituents at the 2-, 4-, and 6-positions. These compounds were examined for their ability to stimulate the ATPase activity of and their affinity for purified human P-glycoprotein (P-gp)-His10, and to promote uptake of Calcein-AM and the efflux of vinblastine in multidrug-resistant, P-gp-overexpressing MDCKII-MDR1 cells. Furthermore, they were examined for their effect on human MRP1-mediated uptake of tritiated estradiol glucuronide ([3H]E217 & beta;G) into inside-out membrane vesicles. After analysis, derivatives with thioamide functionality in the 4-position were more active against MRP1 than derivatives with amide functionality in the 4-position. Conversely, amides were more active against P-gp than thioamides. Although determined to be micromolar modulators of both transporters, the potential exists for use of these compounds as photosensitizers for the treatment of MRP1- and P-gp-expressing cells by photodynamic therapy (PDT). Through inactivation of either efflux pump by PDT, a dual cancer treatment regimen involving both PDT and conventional chemotherapy may be on the horizon.
