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Central Nervous System Radiotracer Development Bench To Bedside
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Book Synopsis Central Nervous System Radiotracer Development: Bench to Bedside by : International Atomic Energy Agency
Download or read book Central Nervous System Radiotracer Development: Bench to Bedside written by International Atomic Energy Agency and published by . This book was released on 2024-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication provides an overview of central nervous system (CNS) radiotracer development, discussing different aspects and stages of development. Non-invasive neuroimaging with radiotracers can provide functional information at the cellular level and contributes substantially to understanding the complex mechanisms of the functioning and pathophysiological processes in the human brain and is useful in certain diseases for patient stratification, treatment response monitoring and as an aided technique for drug development. The success of the development of clinically significant radiotracers depends on many factors such as the selected biological target, specificity and affinity of the radio ligand, pharmacokinetics of radiotracer and others. The information provided in the document will be useful to researchers, students and professionals engaged in the development and deployment of CNS radiotracers for clinical, research or drug development applications
Book Synopsis PET/CT Atlas on Quality Control and Image Artefacts by : International Atomic Energy Agency
Download or read book PET/CT Atlas on Quality Control and Image Artefacts written by International Atomic Energy Agency and published by . This book was released on 2014 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: Positron emission tomography/computed tomography (PET/CT), as any other imaging modality, is acceptable for routine clinical and research applications only if technical pitfalls can be avoided. Artefacts from incorrect or sub-optimal acquisition procedures should be recognized and, if possible, corrected retrospectively and the resulting image information interpreted correctly, which entails an appreciation of variants of the represented image information. This publication provides guidance on the physics and technical aspects behind PET and PET/CT image distortions. Cases are presented to provide nuclear medicine and radiology professionals with an assortment of examples of possible image distortions and errors in order to support a correct image interpretation. Nearly 70 typical PET and PET/CT cases, comprising image sets and cases, have been collected in this volume, all catalogued and augmented with explanations as to the causes of, and solutions to, each individual image problem. The atlas will prove useful to physicists, physicians, technologists, and service engineers in the clinical field.
Book Synopsis Gene Therapy of the Central Nervous System: From Bench to Bedside by : Michael G. Kaplitt
Download or read book Gene Therapy of the Central Nervous System: From Bench to Bedside written by Michael G. Kaplitt and published by Gulf Professional Publishing. This book was released on 2006 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Few areas of biomedical research provide greater opportunities to capitalize upon the revolution in genomics and molecular biology than gene therapy. This is particularly true for the brain and nervous system, where gene transfer has become a key technology for basic research and has recently been translated to human therapy in several landmark clinical trials. Gene Therapy in the Brain: From Bench to Bedside represents the definitive volume on this subject. Edited by two pioneers of neurological gene therapy, this volume contains contributions by leaders who helped to create the field as well as those who are expanding the promise of gene therapy for the future of basic and clinical neuroscience. Drawing upon this extensive collective experience, this book provides clear and informative reviews on a variety of subjects which would be of interest to anyone who is currently using or contemplating exploring gene therapy for neurobiological applications. Basic gene transfer technologies are discussed, with particular emphases upon novel vehicles, immunological issues and the role of gene therapy in stem cells. Numerous research applications are reviewed, particularly in complex fields such as behavioral neurobiology. Several preclinical areas are also covered which are likely to translate into clinical studies in the near future, including epilepsy, pain and amyotrophic lateral sclerosis. Among the most exciting advances in recent years has been the use of neurological gene therapy in human clinical trials, including Parkinson's disease, Canavan disease and Batten disease. Finally, readers will find "insider" information on technological and regulatory issues which can often limit effective translation of even the most promising idea into clinical use. This work provides up-to-date information and key insights into those gene therapy issues which are important to both scientists and clinicians focusing upon the brain and central nervous system.
Book Synopsis Advancing Nuclear Medicine Through Innovation by : National Research Council
Download or read book Advancing Nuclear Medicine Through Innovation written by National Research Council and published by National Academies Press. This book was released on 2007-09-11 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.
Author :International Atomic Energy Agency Publisher :International Atomic Energy Agency ISBN 13 :9789201040190 Total Pages : pages Book Rating :4.0/5 (41 download)
Book Synopsis Nuclear Medicine Resources Manual by : International Atomic Energy Agency
Download or read book Nuclear Medicine Resources Manual written by International Atomic Energy Agency and published by International Atomic Energy Agency. This book was released on 2021-03-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical imaging is crucial in a variety of medical settings and at all levels of health care. In public health and preventive medicine as well as in both curative and palliative care, effective decisions depend on correct diagnoses. This edition addresses the most current needs and offers guidance on clinical practice, radiation safety and patient protection, human resource development and training required for the overall practice of nuclear medicine.
Book Synopsis Spet/CT Atlas on Quality Control and Image Artefacts by : International Atomic Energy Agency
Download or read book Spet/CT Atlas on Quality Control and Image Artefacts written by International Atomic Energy Agency and published by . This book was released on 2019-12-31 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: SPECT/CT Atlas of Quality Control and Image Artefacts
Book Synopsis Nuclear Oncology by : H. William Strauss
Download or read book Nuclear Oncology written by H. William Strauss and published by Springer Science & Business Media. This book was released on 2012-11-27 with total page 873 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with a comprehensive understanding of both the basic principles and the clinical applications of nuclear oncology imaging techniques. The authors have assembled a distinguished group of leaders in the field who provide valuable insight on the subject. The book also includes major chapters on the cancer patient and the pathophysiology of abnormal tissue, the evaluation of co-existing disease, and the diagnosis and therapy of specific tumors using functional imaging studies. Each chapter is heavily illustrated to assist the reader in understanding the clinical role of nuclear oncology in cancer disease therapy and management.
Book Synopsis Diagnostic Radiology Physics by : International Atomic Energy Agency
Download or read book Diagnostic Radiology Physics written by International Atomic Energy Agency and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication is aimed at students and teachers involved in programmes that train medical physicists for work in diagnostic radiology. It provides a comprehensive overview of the basic medical physics knowledge required in the form of a syllabus for the practice of modern diagnostic radiology. This makes it particularly useful for graduate students and residents in medical physics programmes. The material presented in the publication has been endorsed by the major international organizations and is the foundation for academic and clinical courses in both diagnostic radiology physics and in emerging areas such as imaging in radiotherapy.
Book Synopsis Clinical PET and PET/CT by : H. Jadvar
Download or read book Clinical PET and PET/CT written by H. Jadvar and published by Springer Science & Business Media. This book was released on 2006-01-20 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical manual covering the full spectrum of PET and PET/CT imaging, now in common clinical practice, this book includes images of normal variants, artifacts, and pathologic conditions. Indications for and the relative clinical value of PET in the armamentarium of diagnostic medical imaging are reviewed. The information in the book is organized to be brief, concise, easy-to-understand and readily accessed. This book is intended for all health practitioners who need a concise reference and review of PET imaging indications, protocols and clinical applications. It will be useful to radiologists, nuclear medicine physicians, and clinicians who refer their patients to PET Centers for diagnostic imaging, including neurologists, neurosurgeons, psychiatrists, cardiologists, internists, and oncologists. Radiologic and nuclear medicine technologists, and physicians in training will also benefit from this work.
Book Synopsis Cardiac CT, PET and MR by : Vasken Dilsizian
Download or read book Cardiac CT, PET and MR written by Vasken Dilsizian and published by John Wiley & Sons. This book was released on 2011-09-14 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This careful revision keeps pace with developments in the field, with new chapters on PET Metabolism, CT and MRI in the Emergency Department, Image-Guided Electrophysiology Mapping and Ablation, and Identification of Vulnerable Atherosclerotic Plaque by Radionuclide and CT techniques, plus the introduction of new contributors Udo Hoffman and Stephan Achenbach. Praised in its previous edition as a concise source of essential information, this new edition presents the most recent information in an accessible format and serves as an excellent reference source for all cardiologists, radiologists and nuclear medicine physicians.
Book Synopsis Production and Quality Control of Fluorine-18 Labelled Radiopharmaceuticals by : International Atomic Energy Agency
Download or read book Production and Quality Control of Fluorine-18 Labelled Radiopharmaceuticals written by International Atomic Energy Agency and published by . This book was released on 2021-10-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since their clinical use initiation in the 1970's, Fluorine-18 (F-18) radiopharmaceuticals continue to play an important role in nuclear medicine. It is therefore essential to make available broad information on practical production routes and optimal quality control for F- 18 tracers, to achieve the best possible products in high quantity and quality for clinical applications while fulfilling all regulatory requirements. This publication describes the chemical and biological properties of F-18 radiopharmaceuticals. This includes aspects relating to F-18 target production and radiofluorination methods, with focus on the applied techniques. The publication presents a disease oriented approach, describing F-18 radiopharmaceuticals, ranging from the physiological/biological aspects to dedicated radiopharmaceutical development approaches and provides readers with clear guidelines and methods for the production of F-18 radiopharmaceuticals.
Book Synopsis Targets, Tracers and Translation – Novel Radiopharmaceuticals Boost Nuclear Medicine by : Gerald Reischl
Download or read book Targets, Tracers and Translation – Novel Radiopharmaceuticals Boost Nuclear Medicine written by Gerald Reischl and published by MDPI. This book was released on 2019-09-20 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the fourth Special Issue in Pharmaceuticals within the last six years dealing with aspects of radiopharmaceutical sciences. It demonstrates the significant interest and increasing relevance to ameliorate nuclear medicine imaging with PET or SPECT, and also radiotherapeutical procedures.Numerous targets and mechanisms have been identified and have been under investigation over the previous years, covering many fields of medical and clinical research. This development is well illustrated by the articles in the present issue, including 13 original research papers and one review, covering a broad range of actual research topics in the field of radiopharmaceutical sciences.
Book Synopsis Atlas of Non-FDG PET-CT in Diagnostic Oncology by : International Atomic Energy Agency
Download or read book Atlas of Non-FDG PET-CT in Diagnostic Oncology written by International Atomic Energy Agency and published by . This book was released on 2021-12-31 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluorodeoxyglucose (FDG) has proven benefits as a positron emission tomography (PET) radiopharmaceutical in oncology.
Book Synopsis Basic Science of PET Imaging by : Magdy M. Khalil
Download or read book Basic Science of PET Imaging written by Magdy M. Khalil and published by Springer. This book was released on 2016-11-07 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.
Book Synopsis Yttrium-90 and Rhenium-188 Radiopharmaceuticals for Radionuclide Therapy by :
Download or read book Yttrium-90 and Rhenium-188 Radiopharmaceuticals for Radionuclide Therapy written by and published by . This book was released on 2015 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A key requirement for the effective implementation of the therapeutic approach, based on the intravenous administration of radiolabelled compounds (radionuclide therapy), is the sufficient availability of radionuclides with appropriate physical characteristics. Based on their nuclear properties, 188Re and 90Y are considered among the most interesting radionuclides for therapy. Furthermore, they are produced through portable generators, which provide a crucial advantage toward ensuring a worldwide distribution of these radionuclides. This publication illustrates recent studies aimed at investigating efficient quality control methods to ensure both the radionuclidic purity of generator eluates, and the proper preparation of new target specific 188Re and 90Y radiopharmaceuticals for various clinical applications."--Publisher's description.
Book Synopsis Production, Quality Control and Clinical Applications of Radiosynovectomy Agents by : International Atomic Energy Agency
Download or read book Production, Quality Control and Clinical Applications of Radiosynovectomy Agents written by International Atomic Energy Agency and published by . This book was released on 2021-08-31 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: Therapeutic radiopharmaceuticals play a major role in today's nuclear medicine with a positive impact on the diagnosis and treatment of diseases. One area of application is radiation synovectomy (RSV).
Book Synopsis Industrial Applications of Sealed Radioactive Sources by : International Atomic Energy Agency
Download or read book Industrial Applications of Sealed Radioactive Sources written by International Atomic Energy Agency and published by . This book was released on 2021-01-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In industrial processes, it is useful to have a range of non-intrusive techniques that can effectively 'look' through vessel and pipe walls to measure process parameters and to identify plant problems. Sealed radioactive sources, specifically those that emit gamma radiation and neutron particles, are ideally suited for these purposes and have been used for industrial applications for many years. This publication describes several available techniques with sealed radioactive sources, by showing examples of their use in industrial applications and by demonstrating how they can be used to improve process efficiency and to save money. The focus of the publication corresponds to two major techniques with sealed radioactive sources: gamma scanning and neutron backscattering, which are largely applied for diagnosis and troubleshooting in processing vessels, columns and in pipes.
