Cellular Rhythms and Networks

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Publisher : Springer
ISBN 13 : 3319228196
Total Pages : 97 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Cellular Rhythms and Networks by : Qing Yan

Download or read book Cellular Rhythms and Networks written by Qing Yan and published by Springer. This book was released on 2015-10-27 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​This book provides an overview of circadian rhythms and cellular networks in their relation to biological systems and dynamical medicine. Six concise chapters explore circadian cell rhythms and biomarkers in inflammation, cardiovascular disease, cancer, depression, and more in causing and treating these ailments. The final chapter discusses optimization of drug delivery and individualized treatment systems using chronotherapy and chronobiology-based biomarkers as a general system of medicine. Succinct yet comprehensive, Cellular Rhythms and Networks, part of SpringerBriefs in Cell Biology presents a novel framework for clinical applications in personalized and systems medicine. It is invaluable reading for researchers and clinicians in cell biology, mood disorders, and systems medicine.

Biochemical Oscillations and Cellular Rhythms

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Publisher : Cambridge University Press
ISBN 13 : 9780521599467
Total Pages : 632 pages
Book Rating : 4.5/5 (994 download)

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Book Synopsis Biochemical Oscillations and Cellular Rhythms by : Albert Goldbeter

Download or read book Biochemical Oscillations and Cellular Rhythms written by Albert Goldbeter and published by Cambridge University Press. This book was released on 1997-04-03 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the molecular bases of some of the most important biochemical rhythms known at the cellular level. The approach rests on the analysis of theoretical models closely related to experimental observations. Among the main rhythms considered are glycolytic oscillations observed in yeast and muscle, oscillations of cyclic AMP in Dictyostelium amoebae, intracellular calcium oscillation observed in a variety of cell types, the mitotic oscillator that drives the cell division cycle in eukaryotes, pulsatile hormone signaling, and circadian rhythms in Drosophila. This book will be of interest to life scientists such as biochemists, cell biologists, chronobiologists, medical scientists and pharmacologists. In addition, it will appeal to scientists studying nonlinear phenomena, including oscillations and chaos, in chemistry, physics, mathematics and theoretical biology.

Circadian Rhythm

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1789233380
Total Pages : 168 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Circadian Rhythm by : Mohamed A. El-Esawi

Download or read book Circadian Rhythm written by Mohamed A. El-Esawi and published by BoD – Books on Demand. This book was released on 2018-07-04 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Circadian clocks are endogenous and temperature-compensating timekeepers that provide temporal organization of biological processes in living organisms. Circadian rhythms allow living organisms to adapt to the daily light cycles associated with Earth's rotation and to anticipate and prepare for precise and regular environmental changes. This book discusses the fundamental advances of how the circadian clock regulates critical biological functions as well as the cellular and molecular mechanisms controlling circadian rhythm in living organisms. It also provides new insights into and sheds new light on the current research trends and future research directions related to circadian rhythm. This book provokes interest in many readers, researchers and scientists, who can find this information useful for the advancement of their research works towards a better understanding of circadian rhythm regulatory mechanisms.

The Cellular Aspects of Biorhythms

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Publisher : Springer Science & Business Media
ISBN 13 : 364288394X
Total Pages : 205 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis The Cellular Aspects of Biorhythms by : Heinz v. Mayersbach

Download or read book The Cellular Aspects of Biorhythms written by Heinz v. Mayersbach and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although in the past the Swedish anatomical schools gave one of the first impulses to the study of biorhythms, this subject has never been a favourite matter of mor phological investigations. The proposal of the organizing committee at the 8th Inter national Anatomical Congress to organize a symposium on rhythmic research was willingly accepted. It was felt that as morphology is growing to be more and more an experimental discipline, biorhythms should be considered. It is gratefully acknowledged that investigators with great experience in biologic rhythms were prepared to take part in this symposium. Their different fields of research, physiology, biology, embryology and clinical, indicate the importance of rhythmic variations and mathematicians show how results gained have to be treated in a correct statistical fashion. There are the processes of cell multiplication, regeneration and growth, which have been proved to be rhythmic. The analyses of mitoses show to what extent such strong interventions as adrenalectomy, hypophysectomy etc. have been misinterpreted and delivered severally contradictory results when the rhythmic variations are not considered. The observation of tissues collected throughout 24 hours contributes to the much debated problem of "Amitosis" and also revealed a definite rhythm of DNA. In connection with this is the uptake and incorporation of DNA-precursors which occur rhythmically. In the vast number of precursor experiments which frequently vary strongly in their results, circadian changes have hardly been considered until now.

Biochemical Oscillations and Cellular Rhythms

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Publisher : Cambridge University Press
ISBN 13 : 0521403073
Total Pages : 632 pages
Book Rating : 4.5/5 (214 download)

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Book Synopsis Biochemical Oscillations and Cellular Rhythms by : A. Goldbeter

Download or read book Biochemical Oscillations and Cellular Rhythms written by A. Goldbeter and published by Cambridge University Press. This book was released on 1996-01-26 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the molecular bases of some of the most important biochemical rhythms known at the cellular level. Clarifying the mechanism of these oscillatory phenomena is of key importance for understanding the origin as well as the physiological function of these rhythms, and the conditions in which simple periodic behaviour transforms into complex oscillations, including bursting and chaos. The approach rests on the analysis of theoretical models closely related to experimental observations. Among the main rhythms considered are glycolytic oscillations observed in yeast and muscle, oscillations of cyclic AMP in Dictyostelium amoebae, intracellular calcium oscillations observed in a variety of cell types, the mitotic oscillator that drives the cell division cycle in eukaryotes, and circadian oscillations of the period protein (PER) in Drosophila. For each of these phenomena, experimental facts are reviewed and mathematical models presented.

Cellular and Molecular Bases of Biological Clocks

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Publisher : Springer Science & Business Media
ISBN 13 : 1461237424
Total Pages : 513 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Cellular and Molecular Bases of Biological Clocks by : Leland N. Jr. Edmunds

Download or read book Cellular and Molecular Bases of Biological Clocks written by Leland N. Jr. Edmunds and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: An intriguing class of biological periodicity consists of rhythms with about 24-hour periods occurring at every level of eukaryotic organization. Progress is being made in understanding these rhythms. The six chapters of this work include a brief introduction to circadian (24-hour) rhythms, a survey of circadian organization at the cellular level, and a description of the important microorganisms that have served as experimental models for biochemical analysis. Also considered are relations between cell division cycles and circadian oscillators, as well as some general and theoretical aspects. Where appropriate, parallels are drawn to neuronal oscillators. This volume will introduce and critically appraise modern chronobiology; its extensive illustrations and comprehensive up-to-date bibliography will make it an authoritative reference.

Military Strategies for Sustainment of Nutrition and Immune Function in the Field

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Author :
Publisher : National Academies Press
ISBN 13 : 0309173183
Total Pages : 722 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Military Strategies for Sustainment of Nutrition and Immune Function in the Field by : Institute of Medicine

Download or read book Military Strategies for Sustainment of Nutrition and Immune Function in the Field written by Institute of Medicine and published by National Academies Press. This book was released on 1999-05-13 with total page 722 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every aspect of immune function and host defense is dependent upon a proper supply and balance of nutrients. Severe malnutrition can cause significant alteration in immune response, but even subclinical deficits may be associated with an impaired immune response, and an increased risk of infection. Infectious diseases have accounted for more off-duty days during major wars than combat wounds or nonbattle injuries. Combined stressors may reduce the normal ability of soldiers to resist pathogens, increase their susceptibility to biological warfare agents, and reduce the effectiveness of vaccines intended to protect them. There is also a concern with the inappropriate use of dietary supplements. This book, one of a series, examines the impact of various types of stressors and the role of specific dietary nutrients in maintaining immune function of military personnel in the field. It reviews the impact of compromised nutrition status on immune function; the interaction of health, exercise, and stress (both physical and psychological) in immune function; and the role of nutritional supplements and newer biotechnology methods reported to enhance immune function. The first part of the book contains the committee's workshop summary and evaluation of ongoing research by Army scientists on immune status in special forces troops, responses to the Army's questions, conclusions, and recommendations. The rest of the book contains papers contributed by workshop speakers, grouped under such broad topics as an introduction to what is known about immune function, the assessment of immune function, the effect of nutrition, and the relation between the many and varied stresses encountered by military personnel and their effect on health.

Human Circadian Physiology

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Publisher :
ISBN 13 :
Total Pages : 692 pages
Book Rating : 4.:/5 (84 download)

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Book Synopsis Human Circadian Physiology by : Charles A. Czeisler

Download or read book Human Circadian Physiology written by Charles A. Czeisler and published by . This book was released on 1978 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biological Clocks, Rhythms, and Oscillations

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Author :
Publisher : MIT Press
ISBN 13 : 0262552817
Total Pages : 369 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Biological Clocks, Rhythms, and Oscillations by : Daniel B. Forger

Download or read book Biological Clocks, Rhythms, and Oscillations written by Daniel B. Forger and published by MIT Press. This book was released on 2024-08-06 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the mathematical, computational, and analytical techniques used for modeling biological rhythms, presenting tools from many disciplines and example applications. All areas of biology and medicine contain rhythms, and these behaviors are best understood through mathematical tools and techniques. This book offers a survey of mathematical, computational, and analytical techniques used for modeling biological rhythms, gathering these methods for the first time in one volume. Drawing on material from such disciplines as mathematical biology, nonlinear dynamics, physics, statistics, and engineering, it presents practical advice and techniques for studying biological rhythms, with a common language. The chapters proceed with increasing mathematical abstraction. Part I, on models, highlights the implicit assumptions and common pitfalls of modeling, and is accessible to readers with basic knowledge of differential equations and linear algebra. Part II, on behaviors, focuses on simpler models, describing common properties of biological rhythms that range from the firing properties of squid giant axon to human circadian rhythms. Part III, on mathematical techniques, guides readers who have specific models or goals in mind. Sections on “frontiers” present the latest research; “theory” sections present interesting mathematical results using more accessible approaches than can be found elsewhere. Each chapter offers exercises. Commented MATLAB code is provided to help readers get practical experience. The book, by an expert in the field, can be used as a textbook for undergraduate courses in mathematical biology or graduate courses in modeling biological rhythms and as a reference for researchers.

Biochemical Oscillations and Cellular Rhythms

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Author :
Publisher : Cambridge University Press
ISBN 13 : 9780521599467
Total Pages : 632 pages
Book Rating : 4.5/5 (994 download)

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Book Synopsis Biochemical Oscillations and Cellular Rhythms by : Albert Goldbeter

Download or read book Biochemical Oscillations and Cellular Rhythms written by Albert Goldbeter and published by Cambridge University Press. This book was released on 1997-04-03 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the molecular bases of some of the most important biochemical rhythms known at the cellular level. The approach rests on the analysis of theoretical models closely related to experimental observations. Among the main rhythms considered are glycolytic oscillations observed in yeast and muscle, oscillations of cyclic AMP in Dictyostelium amoebae, intracellular calcium oscillation observed in a variety of cell types, the mitotic oscillator that drives the cell division cycle in eukaryotes, pulsatile hormone signaling, and circadian rhythms in Drosophila. This book will be of interest to life scientists such as biochemists, cell biologists, chronobiologists, medical scientists and pharmacologists. In addition, it will appeal to scientists studying nonlinear phenomena, including oscillations and chaos, in chemistry, physics, mathematics and theoretical biology.

Stochasticity and Synchrony in the Mammalian Circadian Network

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Author :
Publisher :
ISBN 13 : 9781339218670
Total Pages : 70 pages
Book Rating : 4.2/5 (186 download)

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Book Synopsis Stochasticity and Synchrony in the Mammalian Circadian Network by : John H. Abel

Download or read book Stochasticity and Synchrony in the Mammalian Circadian Network written by John H. Abel and published by . This book was released on 2015 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: A vast majority of life on Earth exists in an environment where resource availability and environmental conditions are temporally periodic. There is therefore an evolutionary advantage for organisms to partition behavior into certain times of day. Circadian rhythms, endogenous near-24 hour oscillations in gene expression, perform this task. These rhythms exert control over a large fraction of biological processes, and as such are implicated in a wide range of diseases, especially metabolic and mental disorders. Circadian rhythms are generated at a single-cell level through a complex set of interlocked genetic feedback loops. Individual components of the circadian network are considered "sloppy" due to stochastic noise, and it is only through the interaction of cellular oscillators at a network level that precise rhythms are generated. Medically treating or reverse-engineering this complicated genetic architecture necessitates mathematical understanding at multiple physical scales, from cells to tissue.

The Biological Clock

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Publisher : Academic Press
ISBN 13 : 1483282287
Total Pages : 103 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis The Biological Clock by : Frank A. Brown

Download or read book The Biological Clock written by Frank A. Brown and published by Academic Press. This book was released on 2014-06-28 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Biological Clock describes the rhythmic processes in a great variety of plants and animals. This book is an outgrowth of the 1969 James Arthur Lecture Series on "Time and its Mysteries" held at New York University. This three-chapter work begins with the basic principles of biological rhythms and clocks, along with various diagrams to illustrate some aspects of circadian rhythms in animals. The second chapter discusses the hypothesis of environmental timing of the clock. This chapter explores numerous research studies on phenomenon of biological rhythms, the nature of the rhythmic mechanism, and hormonal regulation. The third chapter examines the cellular-biochemical clock hypothesis and its contribution in the progress of understanding the complexity of biological rhythm. This book is intended primarily for biologists, behaviorists, and researchers.

The Neurobiology of Circadian Timing

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Author :
Publisher : Elsevier
ISBN 13 : 044459454X
Total Pages : 513 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis The Neurobiology of Circadian Timing by :

Download or read book The Neurobiology of Circadian Timing written by and published by Elsevier. This book was released on 2012-12-06 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future researchChapters are extensively referenced to provide readers with a comprehensive list of resources on the topics coveredAll chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist - Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research - Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered - All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

The Circadian Clock

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1441912622
Total Pages : 306 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis The Circadian Clock by : Urs Albrecht

Download or read book The Circadian Clock written by Urs Albrecht and published by Springer Science & Business Media. This book was released on 2010-01-23 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the invitation to edit this volume, I wanted to take the opportunity to assemble reviews on different aspects of circadian clocks and rhythms. Although most c- tributions in this volume focus on mammalian circadian clocks, the historical int- duction and comparative clocks section illustrate the importance of various other organisms in deciphering the mechanisms and principles of circadian biology. Circadian rhythms have been studied for centuries, but only recently, a mole- lar understanding of this process has emerged. This has taken research on circadian clocks from mystic phenomenology to a mechanistic level; chains of molecular events can describe phenomena with remarkable accuracy. Nevertheless, current models of the functioning of circadian clocks are still rudimentary. This is not due to the faultiness of discovered mechanisms, but due to the lack of undiscovered processes involved in contributing to circadian rhythmicity. We know for example, that the general circadian mechanism is not regulated equally in all tissues of m- mals. Hence, a lot still needs to be discovered to get a full understanding of cir- dian rhythms at the systems level. In this respect, technology has advanced at high speed in the last years and provided us with data illustrating the sheer complexity of regulation of physiological processes in organisms. To handle this information, computer aided integration of the results is of utmost importance in order to d- cover novel concepts that ultimately need to be tested experimentally.

Circadian Rhythms and Metabolism

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889452824
Total Pages : 190 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Circadian Rhythms and Metabolism by : Etienne Challet

Download or read book Circadian Rhythms and Metabolism written by Etienne Challet and published by Frontiers Media SA. This book was released on 2017-09-18 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major breakthroughs of the last decade in the understanding of energy homeostasis is the identification of a reciprocal control between circadian rhythmicity and cellular metabolism. Circadian rhythmicity is a fundamental endogenous process of almost every organism living on Earth. For instance, the alternation of hunger and satiety is not continuous over 24 h, but is instead structured in time along the light/dark cycle. In mammals, the temporal organization of metabolism, physiology and behavior around 24 h is controlled by a network of multiple cellular clocks, synchronized via neuronal and hormonal signals by a master clock located in the suprachiasmatic nuclei of the hypothalamus. This central circadian conductor in the brain is mainly reset by ambient light perceived by the retina, while secondary circadian clocks in other brain areas and peripheral organs can be reset by meal timing. Chronic disruption of circadian rhythms, as seen in human shift-workers (up to 20% of the active population), has been associated with the development of a number of adverse mental and metabolic conditions. Understanding of the functional links between circadian desynchronization and overall health in animal models and humans, however, is still scarce. Interactions between circadian clocks and metabolism can occur at different levels: the molecular clockwork, internal synchronization via neuro-hormonal signals, or external synchronization via photic or feeding cues. This Research Topic comprises a number of reviews as well as research and methods articles that feature recent advancements in the mechanisms linking circadian clocks with energy metabolism, and the pathophysiological implications of these interactions for metabolic health.

Chronobiology and Chronomedicine

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Publisher : Royal Society of Chemistry
ISBN 13 : 1839167564
Total Pages : 535 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis Chronobiology and Chronomedicine by : Germaine Cornelissen

Download or read book Chronobiology and Chronomedicine written by Germaine Cornelissen and published by Royal Society of Chemistry. This book was released on 2024-02-23 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: Circadian rhythms have been shown to be ubiquitous and critically important in the experimental laboratory, accounting for the difference between life and death in response to identical stimulus. The partly endogenous nature of circadian rhythms has been well documented and methods for their characterisation have been developed enabling the cellular and molecular mechanisms to be understood. Chronobiology and Chronomedicine aims to provide a review of these mechanisms underlying circadian rhythms and illustrate the role of the brain’s suprachiasmatic nuclei in the ‘pace-making’ process and the effects caused by ‘clock genes’ present in almost all cells. Beyond the mechanisms involved, the book discusses the relationship between body systems, disease, and proper circadian function; in particular, how disruption of the circadian rhythm is associated with ill health and disease status from observations made at the organismic level. The book is organised to be an ideal introduction for the postgraduate in various fields, reviewing developments and outlining methods to show the depth and breadth of chronobiology and chronomedicine, as well as an invaluable companion to researchers and healthcare professionals working in the field with an interest in developing novel therapeutic approaches.

Development of Circadian Clock Functions, volume II

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Publisher : Frontiers Media SA
ISBN 13 : 2832552285
Total Pages : 124 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Development of Circadian Clock Functions, volume II by : Daisuke Ono

Download or read book Development of Circadian Clock Functions, volume II written by Daisuke Ono and published by Frontiers Media SA. This book was released on 2024-07-31 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: The temporal order of physiological functions such as sleep/wakefulness is regulated by the circadian clock. This intrinsic clock starts ticking in the embryo and matures during development, with attenuation of the clock function in the elderly, illustrated by attenuation of synchrony, entrainment, and outputs of cellular circadian rhythms in the SCN. This age-related diminution can contribute to the emergence of diseases, such as sleep disorders, infertility, diabetes, mental disorders etc. Over the course of our lives, a variety of internal and external factors are under the influence of the circadian clock. This inherent developmental plasticity of the circadian system is critical for the establishment of normal bodily functions to adapt to the changing environment on earth. In mammals, the central circadian clock is located in the suprachiasmatic nucleus (SCN) of the hypothalamus. Circadian rhythms in the SCN are observed during the embryonic period, and input and output pathways from the SCN are formed after birth. During postnatal development, functions of neurotransmitters in the SCN are changed, which have an influence on special temporal patterns of circadian rhythms in the SCN and outputs signals to the outside of the SCN. During postnatal development properties of circadian rhythms in the SCN and its inputs and outputs can be modulated by environmental light conditions. Recent optical manipulation and imaging techniques have revealed that cell type specific functions for circadian rhythms. However, it remains unclear which cell types or networks in the brain are modulated during postnatal development, and how these cells regulate circadian rhythms depending on postnatal period.