Cellular And Molecular Toxicology Of Nanoparticles

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Cellular and Molecular Toxicology of Nanoparticles

Author : Quaiser Saquib
Publisher : Springer
ISBN 13 : 3319720414
Total Pages : 346 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Cellular and Molecular Toxicology of Nanoparticles by : Quaiser Saquib

Download or read book Cellular and Molecular Toxicology of Nanoparticles written by Quaiser Saquib and published by Springer. This book was released on 2018-02-16 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited book is a compilation of findings on the molecular and cellular toxicity of nanoparticles (NPs) in animal cell, human cells, invertebrates. The varied selection of test models will provide better understanding about the horizon of NPs toxicity. Interaction of NPs with cells and its organelles can induce toxicological consequences, including transcriptional and translational alterations, DNA damage, cytotoxicity, oxidative stress, mitochondrial dysfunction and cell death. NPs can get internalized in cells through phagocytosis, macropinocytosis, receptor-mediated endocytosis and passive penetration, which can affect varied cell types. Readers will be benefited with the compilations on basic and molecular facet of NPs toxicity. The chapters will provide a comprehensive information on the state-of-the-art methodologies. The application of toxicogenomic approaches, which is already established in nanotoxicology, has been given special consideration to unravel the toxicodynamics of nanomaterials. Among these approaches, the high-throughput RNA sequencing (RNA-Seq), which is able to build a complete map of transcriptome across different cell types and perturbations upon NPs exposure has been included. The readers are also introduced to the less studied topic on the adsorption of biomolecules (mainly proteins) on the NPs surface, constituting the so-called “biomolecular corona”. The book has been designed for scientists engaged in NPs toxicity research. Nonetheless, it should be of interest to a variety of scientific disciplines including marine biology, environmental pollution, genetics, pharmacology, medicine, drug and food material sciences, consumer products. Also, the compilations will be of interest to the environmental watchdogs, federal regulators, risk assessors and the policy makers.

Toxicology of Nanomaterials

Author : Yuliang Zhao
Publisher : John Wiley & Sons
ISBN 13 : 352768915X
Total Pages : 432 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Toxicology of Nanomaterials by : Yuliang Zhao

Download or read book Toxicology of Nanomaterials written by Yuliang Zhao and published by John Wiley & Sons. This book was released on 2016-09-08 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with a comprehensive view of analytical methods for nanotoxicology studies. After an introduction to nanomaterials and toxicological studies, the book discusses various characterization methods of nanomaterials and continues with the detection of nanoparticles in vivo as well as in vitro. A variety of techniques in molecular toxicology of nanomaterials is presented, followed by a detailed explanation of interaction between nanoparticles and biomacromolecules, including the structure-toxicity relationships of nanomaterials. Finally, the book concludes with the advantages and challenges of the analytical methods for nanotoxicology.

Biological Responses to Nanoscale Particles

Author : Peter Gehr
Publisher : Springer
ISBN 13 : 3030124614
Total Pages : 344 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Biological Responses to Nanoscale Particles by : Peter Gehr

Download or read book Biological Responses to Nanoscale Particles written by Peter Gehr and published by Springer. This book was released on 2019-04-16 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book the recent progress accumulated in studies of the interaction of engineered nanoparticles with cells and cellular constituents is presented. The focus is on manufacturing and characterization of nanosized materials, their interactions with biological molecules such as proteins, the mechanisms of transport across biological membranes as well as their effects on biological functions. Fundamental molecular and cellular aspects are in the foreground of the book. A further particularity is the interdisciplinary approach, including fields such as preparatory and analytical chemistry, biophysics and the physics of colloids, advanced microscopy and spectroscopy for in-situ detection of nanoparticles, cellular toxicology and nanomedicine. Nanoscale particles are known to exhibit novel and unprecedented properties that make them different from their corresponding bulk materials. As our ability to control these properties is further advanced, a huge potential to create materials with novel properties and applications emerges. Although the technological and economic benefits of nanomaterials are indisputable, concerns have also been raised that nanoscale structuring of materials might also induce negative health effects. Unfortunately, such negative health effects cannot be deduced from the known toxicity of the corresponding macroscopic material. As a result, there is a major gap in the knowledge necessary for assessing their risk to human health.

Biochemical Toxicology

Author : Muharrem Ince
Publisher : BoD – Books on Demand
ISBN 13 : 178984696X
Total Pages : 232 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Biochemical Toxicology by : Muharrem Ince

Download or read book Biochemical Toxicology written by Muharrem Ince and published by BoD – Books on Demand. This book was released on 2020-07-29 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical Toxicology - Heavy Metals and Nanomaterials provides an overview of biochemical contamination, nanomaterials and toxic metals, and measurement techniques. It explains and clarifies important studies and compares and develops new and groundbreaking measurement techniques in the fields of organic and inorganic pollution and nanoscience. It is highly recommended for professionals and readers interested in the environment and human health.

Molecular Toxicology

Author : Nick Plant
Publisher : Taylor & Francis
ISBN 13 : 1000150216
Total Pages : 164 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Molecular Toxicology by : Nick Plant

Download or read book Molecular Toxicology written by Nick Plant and published by Taylor & Francis. This book was released on 2021-02-26 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Toxicology is a concise introduction to the subject, taking the reader through the theoretical principles of toxicology followed by specific examples. In the first section, the concepts behind possible mechanisms of toxicity are described (e.g. the specific enzyme or receptor system) using examples where appropriate. Following this a series of examples are used to show the extension of concept into the real world, in an organ specific manner. The book concludes with a section outlining toxicity assessment methods, where the impact of molecular biology is having a considerable impact, including DNA microarrays, proteomics and bioinformatics.

Advances in Molecular Toxicology

Author :
Publisher : Elsevier
ISBN 13 : 0444538658
Total Pages : 264 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis Advances in Molecular Toxicology by :

Download or read book Advances in Molecular Toxicology written by and published by Elsevier. This book was released on 2011-07-01 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Molecular Toxicology features the latest advances in all of the subspecialties of the broad area of molecular toxicology. Toxicology is the study of poisons, and this series details the study of the molecular basis by which a vast array of agents encountered in the human environment and produced by the human body itself manifest themselves as toxins. Not strictly limited to documenting these examples, the series is also concerned with the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field. Advances in Molecular Toxicology will report progress in all aspects of these rapidly evolving molecular aspects of toxicology with a view toward detailed elucidation of both progress on the molecular level and on advances in technological approaches employed. Cutting-edge reviews by leading workers in the discipline In-depth dissection of molecular aspects of interest to a broad range of scientists, physicians and any student in the allied disciplines Leading edge applications of technological innovations in chemistry, biochemistry and molecular medicine

Nanotoxicology

Author : Alok Dhawan
Publisher : Royal Society of Chemistry
ISBN 13 : 178262158X
Total Pages : 380 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Nanotoxicology by : Alok Dhawan

Download or read book Nanotoxicology written by Alok Dhawan and published by Royal Society of Chemistry. This book was released on 2017-11-13 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book fills the significant nanotoxicology and nanosafety knowledge gaps and covers a broad range of topics. It targets postgraduates, academics, and practicing industrialists.

Molecular and Cellular Mechanisms of Toxicity

Author : Lewis L. Smith
Publisher : CRC Press
ISBN 13 : 1000012824
Total Pages : 262 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Molecular and Cellular Mechanisms of Toxicity by : Lewis L. Smith

Download or read book Molecular and Cellular Mechanisms of Toxicity written by Lewis L. Smith and published by CRC Press. This book was released on 2019-06-04 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1995: Written by specialists in their fields, this book contains short reviews intended to highlight points of growing interest in mechanistic toxicology. The first section considers selected aspects of molecular mechanisms, including selectivity of toxic agents and repair processes in the nervous system, toxicity of oxygen, fibers and aflatoxins. The second section discusses the interactions of carcinogens with DNA, and other targets, and their relevance to both molecular dosimetry of exposure and development of cancer. The final part is concerned with cellular and genetic aspects and includes coverage of some of the most recent and rapidly developing problems in toxicology.

Toxicology of Nanoparticles: Insights from Drosophila

Author : Namita Agrawal
Publisher : Springer Nature
ISBN 13 : 9811555222
Total Pages : 128 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Toxicology of Nanoparticles: Insights from Drosophila by : Namita Agrawal

Download or read book Toxicology of Nanoparticles: Insights from Drosophila written by Namita Agrawal and published by Springer Nature. This book was released on 2020-08-24 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers an unparalleled source of information on in vivo assessment of nanoparticle toxicity by using Drosophila as a model organism. Nanoparticles have emerged as an useful tool for wide variety of biomedical, cosmetics, and industrial applications. However, our understanding of nanomaterial-mediated toxicity under in vivo condition remains limited. The book begins with a chapter on synthesis and characterization of nanoparticles used for various biological, medical and commercial purposes. The rest of the chapters deal with the impact of nanoparticles on different biological aspects like behavior, physiology and metabolic homoeostasis using Drosophila as a model organism. Lastly, the book summarizes how proper characterization and evaluation of safe dosage of nanoparticles can be a boon if incorporated in consumer goods and for biomedical applications. Overall, the book pursues an interdisciplinary approach by connecting nanotechnology and biology from various angles using Drosophila as a model system, so as to develop more efficient, safe and effective use of nanoparticles for human beings.

Handbook of Materials for Nanomedicine

Author : Vladimir Torchilin
Publisher : CRC Press
ISBN 13 : 1000067130
Total Pages : 294 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Handbook of Materials for Nanomedicine by : Vladimir Torchilin

Download or read book Handbook of Materials for Nanomedicine written by Vladimir Torchilin and published by CRC Press. This book was released on 2020-03-16 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the fast-developing field of nanomedicine, a broad variety of materials have been used for the development of advanced delivery systems for drugs, genes, and diagnostic agents. With the recent breakthroughs in the field, we are witnessing a new age of disease management, which is governed by precise regulation of dosage and delivery. This book presents the advances in the use of metal-based and other nanomaterials for medical imaging, diagnosis, theranostics, and drug delivery. It discusses silver, hybrid gold, and surface-modified magnetic nanoparticles, fluorescent quantum dots, lipid bubbles, and nanobubbles. It provides all available information about these materials and describes in detail their advantages and disadvantages and the areas where they could be utilized successfully. The text also covers topics such as improving bioactivity of poorly soluble actives, cellular and molecular toxicology of nanoparticles, and biofate of nanoemulsions.

Nanotoxicology in Humans and the Environment

Author : Jamie R. Lead
Publisher : Springer Nature
ISBN 13 : 3030798089
Total Pages : 263 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Nanotoxicology in Humans and the Environment by : Jamie R. Lead

Download or read book Nanotoxicology in Humans and the Environment written by Jamie R. Lead and published by Springer Nature. This book was released on 2021-12-13 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book covers the area of ‘Nanotoxicology’ but primarily from the point of view of nanotoxicology at the interface with other disciplines including human toxicology; environmental toxicology; characterization, dose and transformations; regulation; public and elite group perceptions; and interactions with innovation.Nanotoxicology in Humans and the Environment is written for researchers in nanotoxicology in academia, industry, government, and research students. Given the rapid development, the maturing of the discipline and its importance in current regulation and industry development (eg REACH, TSCA), the book is very timely.

Nanotoxicity

Author : Joshua Reineke
Publisher : Humana Press
ISBN 13 : 9781627030014
Total Pages : 0 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Nanotoxicity by : Joshua Reineke

Download or read book Nanotoxicity written by Joshua Reineke and published by Humana Press. This book was released on 2012-09-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of nanotechnology has developed very rapidly over the past decade lending great promise to medical applications in drug delivery, therapeutics, and biological imaging. Due to the great promise, rapid development, and broad application of nanomaterials, it is imperative that researchers from development through application seek a thorough understanding of nanotoxicity. Nanotoxicity: Methods and Protocols address the special considerations when applying toxicity studies to nanomaterials and detail newly developed methods for the study of nanotoxicity. These diverse methods span in vitro cell culture, model tissues, in situ exposure, in vivo models, analysis in plants, and mathematical modeling, proving to be relevant to pharmaceutical scientists, material scientists, bioengineers, toxicologists, environmentalists, immunologists, and cellular and molecular biologists, to name a few. As part of the highly successful Methods in Molecular BiologyTM, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Nanotoxicity: Methods and Protocols aims to diversify the capabilities of current researchers involved in nanotoxicology and to enable researchers in related fields to expand their knowledge of how nanomaterials interface with the biological environment.

Molecular and Biochemical Toxicology

Author : Robert C. Smart
Publisher : John Wiley & Sons
ISBN 13 : 1119042437
Total Pages : 1040 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Molecular and Biochemical Toxicology by : Robert C. Smart

Download or read book Molecular and Biochemical Toxicology written by Robert C. Smart and published by John Wiley & Sons. This book was released on 2017-11-06 with total page 1040 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written as an advanced text for toxicology students, this book is much more than an introduction and provides in-depth information describing the underlying mechanisms through which toxicants produce their adverse responses. • Links traditional toxicology to modern molecular techniques, important for teaching to graduate courses and professional studies • Uses a didactic approach with basic biological or theoretical background for the methodology presented • Brings together and comprehensively covers a range of dynamic aspects in biochemical and molecular toxicology • Guides student and professional toxicologists in comprehending a broad range of issues, compiled and authored by a diverse group of experts • “A good introductory textbook covering the biochemical toxicology of organic substances and the relevant methodology in some detail.... It offers good value for money and can be recommended as a textbook for appropriate courses” – BTS Newsletter review of the 4th edition

Toxicity of Nanomaterials

Author : Suresh C. Pillai
Publisher : CRC Press
ISBN 13 : 9780367779757
Total Pages : 246 pages
Book Rating : 4.7/5 (797 download)

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Book Synopsis Toxicity of Nanomaterials by : Suresh C. Pillai

Download or read book Toxicity of Nanomaterials written by Suresh C. Pillai and published by CRC Press. This book was released on 2021-03-31 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, edited by two leading experts in nanotoxicology with contributions from a global team of specialists, provides a comprehensive overview of the risks and environmental and health impacts assosciated with the toxicology of nanomaterials.

Clinical Applications of Magnetic Nanoparticles

Author : Nguyen TK Thanh
Publisher : CRC Press
ISBN 13 : 1351685422
Total Pages : 1408 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Clinical Applications of Magnetic Nanoparticles by : Nguyen TK Thanh

Download or read book Clinical Applications of Magnetic Nanoparticles written by Nguyen TK Thanh and published by CRC Press. This book was released on 2018-02-06 with total page 1408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering the latest information in magnetic nanoparticle (MNP) research, this book builds upon the success of the first volume and provides an updated and comprehensive review, from synthesis, characterization, and biofunctionalization to clinical applications of MNPs, including the diagnosis and treatment of cancers. The book captures some of emerging research area which was not available in the first volume. Good Manufacturing Practices and Commercialization of MNPs are also included. This volume, also written by some of the most qualified experts in the field, incorporates new developments in the literature, and continues to bridge the gaps between the different areas in this field.

Molecular, Clinical and Environmental Toxicology

Author : Andreas Luch
Publisher : Springer Science & Business Media
ISBN 13 : 3764383402
Total Pages : 574 pages
Book Rating : 4.7/5 (643 download)

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Book Synopsis Molecular, Clinical and Environmental Toxicology by : Andreas Luch

Download or read book Molecular, Clinical and Environmental Toxicology written by Andreas Luch and published by Springer Science & Business Media. This book was released on 2012-06-07 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Toxicology is the third volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals of daily life. By providing intriguing insights far down to the molecular level, this three-volume work covers the entire range of modern toxicology with special emphasis on recent developments and achievements. It is written for students and professionals in medicine, science, public health or engineering who are demanding reliable information on toxic or potentially harmful agents and their adverse effects on the human body.

Advances in Molecular Toxicology

Author :
Publisher : Elsevier
ISBN 13 : 0444633901
Total Pages : 278 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Advances in Molecular Toxicology by :

Download or read book Advances in Molecular Toxicology written by and published by Elsevier. This book was released on 2014-10-03 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Molecular Toxicology features the latest advances in all of the subspecialties of the broad area of molecular toxicology. Toxicology is the study of poisons, and this series details the study of the molecular basis by which a vast array of agents encountered in the human environment and produced by the human body itself manifest themselves as toxins. Not strictly limited to documenting these examples, the series is also concerned with the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field. Advances in Molecular Toxicology will report progress in all aspects of these rapidly evolving molecular aspects of toxicology with a view toward detailed elucidation of progress on the molecular level and on advances in technological approaches employed. Cutting-edge reviews by leading workers in the discipline In-depth dissection of molecular aspects of interest to a broad range of scientists, physicians and any student in the allied disciplines Leading edge applications of technological innovations in chemistry, biochemistry and molecular medicine