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Cell Therapy For Brain Injury
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Book Synopsis Cell Therapy for Brain Injury by : David C. Hess
Download or read book Cell Therapy for Brain Injury written by David C. Hess and published by Springer. This book was released on 2015-05-15 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Therapy for Brain Injury is a thorough examination of using state-of-the-art cell therapy in the treatment of strokes and other traumatic brain injuries. This invaluable book covers this niche topic in depth from basic stem cell biology and principles of cell therapy through proposed mechanisms of action of cell therapy in stroke, pre-clinical data in stroke models, ongoing clinical trials, imaging and tracking of cells with MRI, neural stem cells in stroke and the "big pharma" perspective of cell therapy. Each chapter is written by well-known leaders in each field, thus providing a wealth of expertise. The breadth of this book makes it essential reading for neuroscientists, stem cell biologists, researchers or clinical trialists at pharmaceutical or biotechnology companies. It also serves as a thorough introduction for graduate students or post-doctoral fellows who hope to work in these fields.
Book Synopsis Cellular Therapy for Neurological Injury by : Jr., Charles S. Cox
Download or read book Cellular Therapy for Neurological Injury written by Jr., Charles S. Cox and published by CRC Press. This book was released on 2016-04-06 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular Therapy for Neurological Injury discusses the current status of cellular therapy for neurological disorders. The primary areas of focus include traumatic brain injury, stroke (ischemic and hemorrhagic), and spinal cord injury. The book explores cell therapy approaches to these and other conditions, while discussing current advances and a l
Book Synopsis Cell Therapy, Stem Cells and Brain Repair by : Cyndy D. Davis
Download or read book Cell Therapy, Stem Cells and Brain Repair written by Cyndy D. Davis and published by Springer Science & Business Media. This book was released on 2007-11-09 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: As our world continues to evolve, the field of regenerative medicine f- lows suit. Although many modern day therapies focus on synthetic and na- ral medicinal treatments for brain repair, many of these treatments and prescriptions lack adequate results or only have the ability to slow the p- gression of neurological disease or injury. Cell therapy, however, remains the most compelling treatment for neurodegenerative diseases, disorders, and injuries, including Parkinson’s disease, Huntington’s disease, traumatic brain injury, and stroke, which is expanded upon in more detail in Chapter 1 by Snyder and colleagues. Cell therapy is also unique in that it is the only therapeutic strategy that strives to replace lost, damaged, or dysfunctional cells with healthy ones. This repair and replacement may be due to an administration of exogenous cells itself or the activation of the body’s own endogenous reparative cells by a trophic, immune, or inflammatory response to cell transplantation. However, the precise mechanism of how cell therapy works remains elusive and is c- tinuing to be investigated in terms of molecular and cellular responses, in particular. Moreover, Chapter 11 by Emerich and associates, discusses some of the possibilities of cell immunoisolation and the potential for treating central nervous system diseases.
Book Synopsis Progenitor Cell Therapy for Neurological Injury by : Charles S. Cox, Jr.
Download or read book Progenitor Cell Therapy for Neurological Injury written by Charles S. Cox, Jr. and published by Springer Science & Business Media. This book was released on 2010-11-25 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are currently no reparative therapies for severe neurological injury, including brain injury, spinal cord injury and stroke. Actually, most treatments are designed simply to limit secondary damage. However, pre-clinical data supports the idea that exogenous stem and progenitor cells have the potential to promote a reparative response to severe neurological injuries. Progenitor Cell Therapy for Neurological Injury is a compilation of seminal essays that explore many unique aspects of neurological injury, focusing on the critical translational issues of cell delivery. Specifically, it discusses routes of administration, types of progenitor cells (alone and/or in combinations), timing of delivery and adjuncts to promote cell engraftment, survival and effectiveness. In addition, many chapters address measuring the effects of transplanted cells and cell tracking. The paradigms of how cell-based therapeutics affect neurological injury is changing rapidly. The developments in this field may ultimately offer realistic hope for improvement in patients with severe injuries. This book is a vital key toward unlocking those future treatments.
Book Synopsis Translational Research in Traumatic Brain Injury by : Daniel Laskowitz
Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2015-12-01 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.
Book Synopsis Cell Therapy for Perinatal Brain Injury by : Haruo Shintaku
Download or read book Cell Therapy for Perinatal Brain Injury written by Haruo Shintaku and published by Springer. This book was released on 2018-03-01 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a wealth of insights, advances and new perspectives on cell therapy for different types of neonatal ischemic disease, such as Hypoxic-Ischemic Encephalopathy (HIE), Periventricular Leukomalacia (PVL) and neonatal infarction. These diseases pose serious challenges for neonatologists and neurologists, because the severe sequelae lead to decreasing QOL for patients and their families. Accordingly, new treatments for neonatal ischemic diseases are needed all over the world. The book develops new effective therapies combined with hypothermia therapy, an established treatment for HIE. After reviewing past approaches, it presents cutting-edge topics in cell therapy, one of the most promising candidates for treating neonatal ischemic disease. Cell Therapy for Neonatal Ischemic Disease will offer readers a better understanding of the current state of the art in this field from bench to bedside, and inspire researchers and physicians to further explore this evolving therapy.
Book Synopsis Neurological Regeneration by : Phuc Van Pham
Download or read book Neurological Regeneration written by Phuc Van Pham and published by Springer. This book was released on 2018-07-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This invaluable resource explores the regenerative potential of stem cells in the nervous system, with a focus on clinical applications. The expertly authored chapters discuss cell-based therapies for spinal cord injury and regeneration, traumatic brain injury, glioblastoma, Parkinson's Disease, ischemic stroke, cell banking, human embryonic stem cells and related concerns, harvesting of adipose tissue, and more. These topics are contextualized within a discussion of future directions of these therapies. Neurological Regeneration, part of Springer’s Stem Cells in Clinical Applications series, is essential reading for scientists, researchers, advanced students and clinicians working in stem cells, neurology, regenerative medicine or tissue engineering.
Book Synopsis Cellular Therapy for Stroke and CNS Injuries by : Li-Ru Zhao
Download or read book Cellular Therapy for Stroke and CNS Injuries written by Li-Ru Zhao and published by Springer. This book was released on 2014-11-24 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular therapy for stroke and neural trauma has gained worldwide attention during the last decade and has shown some promising results. Various cells, including neural stem cells, bone marrow stem cells, endothelial progenitor cells, and many others have had protective or regenerative effects in animal models. The proposed book will address recent research on all relevant cell types. In addition, it will provide information on cell isolation and culture skills, transplantation methods, and neurological functional evaluations. This is the first book to focus on cellular therapy for stroke and other CNS injuries.
Book Synopsis Progenitor Cell Therapy for Neurological Injury by : Charles S. Cox, Jr.
Download or read book Progenitor Cell Therapy for Neurological Injury written by Charles S. Cox, Jr. and published by Humana Press. This book was released on 2011-07-21 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are currently no reparative therapies for severe neurological injury, including brain injury, spinal cord injury and stroke. Actually, most treatments are designed simply to limit secondary damage. However, pre-clinical data supports the idea that exogenous stem and progenitor cells have the potential to promote a reparative response to severe neurological injuries. Progenitor Cell Therapy for Neurological Injury is a compilation of seminal essays that explore many unique aspects of neurological injury, focusing on the critical translational issues of cell delivery. Specifically, it discusses routes of administration, types of progenitor cells (alone and/or in combinations), timing of delivery and adjuncts to promote cell engraftment, survival and effectiveness. In addition, many chapters address measuring the effects of transplanted cells and cell tracking. The paradigms of how cell-based therapeutics affect neurological injury is changing rapidly. The developments in this field may ultimately offer realistic hope for improvement in patients with severe injuries. This book is a vital key toward unlocking those future treatments.
Book Synopsis Brain Neurotrauma by : Firas H. Kobeissy
Download or read book Brain Neurotrauma written by Firas H. Kobeissy and published by CRC Press. This book was released on 2015-02-25 with total page 725 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every year, an estimated 1.7 million Americans sustain brain injury. Long-term disabilities impact nearly half of moderate brain injury survivors and nearly 50,000 of these cases result in death. Brain Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma, including brain injury pathophysiology, biomarker research, experimental models of CNS injury, diagnostic methods, and neurotherapeutic interventions as well as neurorehabilitation strategies in the field of neurotraum research. The book includes several sections on neurotrauma mechanisms, biomarker discovery, neurocognitive/neurobehavioral deficits, and neurorehabilitation and treatment approaches. It also contains a section devoted to models of mild CNS injury, including blast and sport-related injuries. Over the last decade, the field of neurotrauma has witnessed significant advances, especially at the molecular, cellular, and behavioral levels. This progress is largely due to the introduction of novel techniques, as well as the development of new animal models of central nervous system (CNS) injury. This book, with its diverse coherent content, gives you insight into the diverse and heterogeneous aspects of CNS pathology and/or rehabilitation needs.
Book Synopsis Cell-based Therapies for Stroke: Promising Solution or Dead End? by : Paulo Henrique Rosado-de-Castro
Download or read book Cell-based Therapies for Stroke: Promising Solution or Dead End? written by Paulo Henrique Rosado-de-Castro and published by Frontiers Media SA. This book was released on 2020-05-22 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Mesenchymal Stem Cell Derived Exosomes by : Yaoliang Tang
Download or read book Mesenchymal Stem Cell Derived Exosomes written by Yaoliang Tang and published by Academic Press. This book was released on 2015-09-02 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. Introduces the MSC-exosome mediated cell-cell communication Covers the major functional benefits in current MSC-derived exosome studies Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies
Book Synopsis The Incidence and Economic Burden of Injuries in the United States by : Eric Finkelstein
Download or read book The Incidence and Economic Burden of Injuries in the United States written by Eric Finkelstein and published by Oxford University Press, USA. This book was released on 2006 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Useful for public health practitioners, researchers and students, this book provides a look at the incidence and economic burden of injuries. Chapter topics include incidence by detailed categorisations, lifetime medical costs and productivity losses as a result of injuries, and a discussion of trends.
Book Synopsis Cell Therapy Against Cerebral Stroke by : Kiyohiro Houkin
Download or read book Cell Therapy Against Cerebral Stroke written by Kiyohiro Houkin and published by Springer. This book was released on 2017-01-06 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents comprehensive reviews for both translational research and clinical trials on cell therapy for stroke. Cerebral stroke is still a leading cause of death and disability. However, despite intensive research, few treatment options are available. The therapeutic potential of cell transplantation has been studied for various pathological conditions of the central nervous system (CNS) including traumatic brain injury, traumatic spinal cord injury, degenerative disease, demyelinating disease and ischemic stroke, as the injured neural tissue in the CNS has only a limited regenerative capacity. Recently, a growing body of evidence in this field suggests that cell transplantation holds great potential as a form of stroke therapy. The authors, who are experts in the field of neurosurgery, review and discuss optimal cell sources and various issues involved in translational research; further, they outline ongoing clinical trials in Japan.
Book Synopsis Developing Successful Neuroprotective Treatments for TBI: Translational Approaches, Novel Directions, Opportunities and Challenges by : Stefania Mondello
Download or read book Developing Successful Neuroprotective Treatments for TBI: Translational Approaches, Novel Directions, Opportunities and Challenges written by Stefania Mondello and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Book Synopsis Neurological Regeneration by : Phuc Van Pham
Download or read book Neurological Regeneration written by Phuc Van Pham and published by Springer. This book was released on 2017-01-16 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This invaluable resource explores the regenerative potential of stem cells in the nervous system, with a focus on clinical applications. The expertly authored chapters discuss cell-based therapies for spinal cord injury and regeneration, traumatic brain injury, glioblastoma, Parkinson's Disease, ischemic stroke, cell banking, human embryonic stem cells and related concerns, harvesting of adipose tissue, and more. These topics are contextualized within a discussion of future directions of these therapies. Neurological Regeneration, part of Springer’s Stem Cells in Clinical Applications series, is essential reading for scientists, researchers, advanced students and clinicians working in stem cells, neurology, regenerative medicine or tissue engineering.
Book Synopsis Regenerative Medicine and Brain Repair by : Philip V. Peplow
Download or read book Regenerative Medicine and Brain Repair written by Philip V. Peplow and published by Springer Nature. This book was released on with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt:
