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Cell Cycle Checkpoint Control And Dna Repair In The Fission Yeast Schizosaccharomyces Pombe
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Book Synopsis Cell-cycle Checkpoint Control and DNA Repair in the Fission Yeast Schizosaccharomyces Pombe by : Gretchen Scheel Jimenez
Download or read book Cell-cycle Checkpoint Control and DNA Repair in the Fission Yeast Schizosaccharomyces Pombe written by Gretchen Scheel Jimenez and published by . This book was released on 1996 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Rad1-dependent Cell Cycle Checkpoint Control in the Fission Yeast Schizosaccharomyces Pombe by : Karen Elizabeth Knudsen
Download or read book Rad1-dependent Cell Cycle Checkpoint Control in the Fission Yeast Schizosaccharomyces Pombe written by Karen Elizabeth Knudsen and published by . This book was released on 1996 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Analysis of DNA Structure Dependent Checkpoints in Schizosaccharomyces Pombe by : Dominic John Finbar Griffiths
Download or read book Analysis of DNA Structure Dependent Checkpoints in Schizosaccharomyces Pombe written by Dominic John Finbar Griffiths and published by . This book was released on 1996 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Functional Characterization of Conserved Checkpoint Genes by : Gunilla Kanter Smoler
Download or read book Functional Characterization of Conserved Checkpoint Genes written by Gunilla Kanter Smoler and published by . This book was released on 1998 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Molecular Biology of Schizosaccharomyces pombe by : Richard Egel
Download or read book The Molecular Biology of Schizosaccharomyces pombe written by Richard Egel and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fission yeast Schizosaccharomyces pombe is the favoured tool of many productive research groups throughout the world, serving as a useful model for fundamental principles and mechanisms, such as genome organization, differential gene regulation, cell-cycle control, signal transduction, or cellular morphogenesis. This book collates the current state of knowledge derived from molecular studies in this simple eukaryotic microorganism. The entire sequence of its genome has been completed, emphasizing the comparative value and model status of this yeast. The individual chapters, highlighting up-to-date views on prominent aspects of molecular organization, were written by active research scientists, presenting the results of their investigations to other workers in neighbouring fields. This book intends to serve the fission yeast community as a handy source of reference for years to come. It will also be of particular value to the ever-increasing number of researchers starting to look into fission yeast affairs for comparative reasons from other platforms of molecular genetics and cell biology.
Book Synopsis Studies on DNA Repair and Replication Checkpoint Control in the Fission Yeast, Schizosaccharomyces Pombe by : K. Vijay Hegde
Download or read book Studies on DNA Repair and Replication Checkpoint Control in the Fission Yeast, Schizosaccharomyces Pombe written by K. Vijay Hegde and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Analysis of Checkpoints and Dependency Relationships in S. Pombe by : Fahad M. Alkhodairy
Download or read book Analysis of Checkpoints and Dependency Relationships in S. Pombe written by Fahad M. Alkhodairy and published by . This book was released on 1993 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Investigation of the Fission Yeast Response to DNA Damage by : Jacqueline Claire Willson
Download or read book Investigation of the Fission Yeast Response to DNA Damage written by Jacqueline Claire Willson and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cell Cycle Checkpoint Control Protocols by : Howard B. Lieberman
Download or read book Cell Cycle Checkpoint Control Protocols written by Howard B. Lieberman and published by Humana Press. This book was released on 2003-11-14 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of cell cycle regulation is based on the observation that the life cycle of a cell progresses through several distinct phases, G1, M, S, and G2, occurring in a well-defined temporal order. Details of the mechanisms involved are rapidly emerging and appear extraordinarily complex. Furthermore, not only is the order of the phases important, but in normal eukaryotic cells one phase will not begin unless the prior phase is completed successfully. Che- point control mechanisms are essentially surveillance systems that monitor the events in each phase, and assure that the cell does not progress prematurely to the next phase. If conditions are such that the cell is not ready to progress—for example, because of incomplete DNA replication in S or DNA damage that may interfere with chromosome segregation in M—a transient delay in cell cycle progression will occur. Once the inducing event is properly handled— for example, DNA replication is no longer blocked or damaged DNA is repaired—cell cycle progression continues. Checkpoint controls have recently been the focus of intense study by investigators interested in mechanisms that regulate the cell cycle. Furthermore, the relationship between checkpoint c- trol and carcinogenesis has additionally enhanced interest in these cell cycle regulatory pathways. It is clear that cancer cells often lack these checkpoints and exhibit genomic instability as a result. Moreover, several tumor suppressor genes participate in checkpoint control, and alterations in these genes are as- ciated with genomic instability as well as the development of cancer.
Book Synopsis Systems Biology of Cancer by : Sam Thiagalingam
Download or read book Systems Biology of Cancer written by Sam Thiagalingam and published by Cambridge University Press. This book was released on 2015-04-09 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.
Book Synopsis Study on the Rad3-Rad26 DNA Damage Checkpoint Protein Complex in Fission Yeast, Schizosaccharomyces Pombe by : Marius Ionica Poitelea
Download or read book Study on the Rad3-Rad26 DNA Damage Checkpoint Protein Complex in Fission Yeast, Schizosaccharomyces Pombe written by Marius Ionica Poitelea and published by . This book was released on 2005 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Regulation of Homologous Recombinational DNA Repair by DNA Damage and Replication Block Checkpoints in Saccharomyces Cerevisiae by : Edwin Haghnazari
Download or read book Regulation of Homologous Recombinational DNA Repair by DNA Damage and Replication Block Checkpoints in Saccharomyces Cerevisiae written by Edwin Haghnazari and published by . This book was released on 2004 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Nuclear and Cytoplasmic Control of the DNA Damage Checkpoint by : Farokh Dotiwala
Download or read book Nuclear and Cytoplasmic Control of the DNA Damage Checkpoint written by Farokh Dotiwala and published by LAP Lambert Academic Publishing. This book was released on 2009-06-11 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell cycle checkpoints are the means by which cells maintain their genomic integrity and resist factors that are potentially mutagenic. It is well known that there are different checkpoints for different stresses a cell could face, one of them being the DNA damage checkpoint. For long the activity of this checkpoint was thought to be limited to the nucleus. In this and other emerging studies it has now been established that the DNA damage checkpoint can regulate cell cycle arrest, nuclear positioning and movement by controlling cytoplasmic factors and events. This study establishes a novel regulatory mechanism of the DNA damage checkpoint involving vesicular transport system and cytoplasmic, non-proteosomal protein degradation. The study also focuses on the connection between the spindle assembly checkpoint (SAC) and the DNA damage checkpoint. To study this we generate an acentric chromosome with a single DNA double strand break on it. We find that budding yeast cells that have one chromosome with conditional GAL1-Cen centromere turned off cannot activate the SAC and both the sister chromatids of this chromosome get preferentially segregated to the mother cell.
Book Synopsis Cellular Responses to DNA Double-strand Breaks and Impaired Replication Fork Progression in the Fission Yeast Schizosaccharaomyces Pombe by : Sevil Aydanova Sofueva
Download or read book Cellular Responses to DNA Double-strand Breaks and Impaired Replication Fork Progression in the Fission Yeast Schizosaccharaomyces Pombe written by Sevil Aydanova Sofueva and published by . This book was released on 2010 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: Checkpoint signaling and DNA repair are closely connected processes that protect the cell's genetic material from exogenous and endogenous stress and are collectively referred to as the DNA damage response (DDR). Relocalization of checkpoint proteins to chromatin flanking DNA double-strand breaks (DSBs) is critical for DDR. Schizosaccharomyces pombe Crb2, which mediates Chk1 activation by Rad3 ATR, forms ionizing radiation-induced nuclear foci (IRIF) at DSBs. Crb2 C-terminal BRCT domains (BRCT 2 ) bind histone H2A phosphorylated by Tel1 ATM and Rad3 ATR ([gamma]-H2A). This work proposes that cooperative phosphate interactions in the BRCT 2 [gamma]-H2A-binding pocket of Crb2, coupled with Tudor domain interactions with lysine-20 dimethylation of histone H4, facilitate stable recruitment of Crb2 DSBs, which in turn mediates efficient phosphorylation of Chk1. This mechanism of cooperative interactions with the [gamma]-H2A/X phosphate is likely conserved in S. pombe Brc1 and human MDC1 genome maintenance proteins.
Download or read book DNA Replication written by Sonya Vengrova and published by Humana. This book was released on 2016-10-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated and revised, this thorough volume covers a range of methods focusing on systems, including mammalian, yeast, bacterial and archaeal. This second edition of DNA Replication: Methods and Protocols describes approaches to analyze whole genomes to single molecules, as well as both in vivo and in vitro experiments. As a volume in the highly successful Methods in Molecular Biology series, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, DNA Replication: Methods and Protocols, Second Edition provides a collections of methods intended for newcomers to this research field and for established laboratories.
Book Synopsis DNA Repair and Cell Cycle Control by :
Download or read book DNA Repair and Cell Cycle Control written by and published by . This book was released on 2006 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Analysis of the Schizosaccharomyces Pombe DNA Structure Dependent Checkpoint Gene Rad26 by : Rhian Jane Davies
Download or read book Analysis of the Schizosaccharomyces Pombe DNA Structure Dependent Checkpoint Gene Rad26 written by Rhian Jane Davies and published by . This book was released on 1999 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
