Good Cascade Impactor Practices, AIM and EDA for Orally Inhaled Products

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Publisher : Springer Science & Business Media
ISBN 13 : 1461462967
Total Pages : 443 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Good Cascade Impactor Practices, AIM and EDA for Orally Inhaled Products by : Terrence P. Tougas

Download or read book Good Cascade Impactor Practices, AIM and EDA for Orally Inhaled Products written by Terrence P. Tougas and published by Springer Science & Business Media. This book was released on 2013-04-10 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this publication is to introduce a new, simpler and more effective way in which to interpret pharmaceutical aerosol particle size data from orally inhaled products (OIPs). Currently, the compendial and regulatory requirements dictate the need for measurements by full resolution multi-stage cascade impactor (CI), a process that is demanding for the operator, time consuming, prone to experimental error, and challenging for method transfers from one laboratory to another. Furthermore, we shall show that the current practice of reducing information from mass-weighted aerodynamic particle size distribution (APSD) measurements through the use of CI stage groupings is not the most effective decision-making tool for OIP quality control (QC) in comparison with newly introduced, mutually-independent efficient data analysis (EDA) metrics that can be derived either from full resolution or abbreviated impactor measurements (AIM).

A Cascade Impactor for Determining the Drop-size Distribution of Fuel Mists

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Publisher :
ISBN 13 :
Total Pages : 76 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis A Cascade Impactor for Determining the Drop-size Distribution of Fuel Mists by : J. L. Harp

Download or read book A Cascade Impactor for Determining the Drop-size Distribution of Fuel Mists written by J. L. Harp and published by . This book was released on 1955 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Public Health Consequences of E-Cigarettes

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Publisher : National Academies Press
ISBN 13 : 030946837X
Total Pages : 775 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Public Health Consequences of E-Cigarettes by : National Academies of Sciences, Engineering, and Medicine

Download or read book Public Health Consequences of E-Cigarettes written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-05-18 with total page 775 pages. Available in PDF, EPUB and Kindle. Book excerpt: Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes. Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research.

Radioactive Aerosols

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Publisher : Elsevier
ISBN 13 : 0080555985
Total Pages : 187 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Radioactive Aerosols by : Constantin Papastefanou

Download or read book Radioactive Aerosols written by Constantin Papastefanou and published by Elsevier. This book was released on 2011-07-28 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whenever radioactivity is released to the atmosphere, for example by the detonation of nuclear weapons or the testing of nuclear weapons or from nuclear reactor accidents that fraction of it which remains airborne for more than a few hours is liable to be attached to aerosol particles. The resulting radioactive aerosols are carried by atmospheric mixing processes until they settle out or are scavenged by precipitation. The radiation exposure pathway of maximum concern to humans is by inhalation of aerosols and their deposition in the respiratory tract. In this context, it is important to note that radioactive aerosols are commonly of natural origin alos. In particular, the associated radionuclides can be of natural terrestrial origin, such as the decay products of radon gas, or they can e cosmogenic, such as beryllium-7. The exposure of miners of uranium and other ores and minerals to radon and its aerosol-borne decay products is of major significance. The book describes the formation of aerosols, their aerodynamic size distribution, their atmospheric residence time, their sampling and measurement, the range of radioactive aerosols found and studied thus far, including man-made nuclides and radon decay products and their interaction with man, including deposition in the lung and subsequent health effects. - Advanced level science handbook for researchers, scientists and academics - Covers all aspects of radiation exposure in humans, including subsequent health implications - Presents the latest findings and analysis in this highly topical area

Air Monitoring for Toxic Exposures

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Publisher : John Wiley & Sons
ISBN 13 : 047167057X
Total Pages : 702 pages
Book Rating : 4.4/5 (716 download)

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Book Synopsis Air Monitoring for Toxic Exposures by : Henry J. McDermott

Download or read book Air Monitoring for Toxic Exposures written by Henry J. McDermott and published by John Wiley & Sons. This book was released on 2004-10-12 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get the Latest from the Field This book offers ready-to-use information for measuring a wide variety of airborne hazardous materials including chemicals, radon, and bioaerosols. It provides the latest procedures for air sampling, collecting biological and bulk samples, evaluating dermal exposures, and determining the advantages and limitations of a given air monitoring method.

Instrumentation for Fluid Particle Flow

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Publisher : Univ. Press of Mississippi
ISBN 13 : 0080946690
Total Pages : 431 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Instrumentation for Fluid Particle Flow by : S.L. Soo

Download or read book Instrumentation for Fluid Particle Flow written by S.L. Soo and published by Univ. Press of Mississippi. This book was released on 2013-01-15 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: A focus on methods of measurement and options for engineers and scientists performing research and evaluation of particle-fluid flow systems. Improved instrumentation for measurement in this field is an essential element in the progress of research and engineering of multi-phase flow systems. Some of the most original and productive research specialists in the field of particle-fluid flow systems are assembled in this book, which is an important and current reference volume.--[Source inconnue].

Aerosol Science

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Publisher : John Wiley & Sons
ISBN 13 : 1119977924
Total Pages : 522 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Aerosol Science by : Ian Colbeck

Download or read book Aerosol Science written by Ian Colbeck and published by John Wiley & Sons. This book was released on 2014-02-03 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: AEROSOL SCIENCE TECHNOLOGY AND APPLICATIONS Aerosols influence many areas of our daily life. They are at the core of environmental problems such as global warming, photochemical smog and poor air quality. They can also have diverse effects on human health, where exposure occurs in both outdoor and indoor environments. However, aerosols can have beneficial effects too; the delivery of drugs to the lungs, the delivery of fuels for combustion and the production of nanomaterials all rely on aerosols. Advances in particle measurement technologies have made it possible to take advantage of rapid changes in both particle size and concentration. Likewise, aerosols can now be produced in a controlled fashion. Reviewing many technological applications together with the current scientific status of aerosol modelling and measurements, this book includes: Satellite aerosol remote sensing The effects of aerosols on climate change Air pollution and health Pharmaceutical aerosols and pulmonary drug delivery Bioaerosols and hospital infections Particle emissions from vehicles The safety of emerging nanomaterials Radioactive aerosols: tracers of atmospheric processes With the importance of this topic brought to the public's attention after the eruption of the Icelandic volcano Eyjafjallajökull, this book provides a timely, concise and accessible overview of the many facets of aerosol science.

Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents

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Publisher : National Academies Press
ISBN 13 : 0309102111
Total Pages : 87 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents by : National Research Council

Download or read book Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents written by National Research Council and published by National Academies Press. This book was released on 2006-09-07 with total page 87 pages. Available in PDF, EPUB and Kindle. Book excerpt: The National Institute of Allergy and Infectious Diseases (NIAID) gives the highest priority to developing countermeasures against bioterrorism agents that are highly infective when dispersed in aerosol form. Developing drugs to prevent or treat illnesses caused by bioterrorism agents requires testing their effectiveness in animals since human clinical trials would be unethical. At the request of NIAID, the National Academies conducted a study to examine how such testing could be improved. Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents provides recommendations to researchers on selecting the kinds of animal models, aerosol generators, and bioterrorism agent doses that would produce conditions that most closely mimic the disease process in humans. It also urges researchers to fully document experimental parameters in the literature so that studies can be reproduced and compared. The book recommends that all unclassified data on bioterrorism agent studies-including unclassified, unpublished data from U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID)-be published in the open literature. The book also calls on the U.S. Food and Drug Administration to improve the process by which bioterrorism countermeasures are approved based on the results of animal studies.

WADC Technical Report

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Publisher :
ISBN 13 :
Total Pages : 1746 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis WADC Technical Report by : United States. Wright Air Development Division

Download or read book WADC Technical Report written by United States. Wright Air Development Division and published by . This book was released on 1956 with total page 1746 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Aerosol Measurement

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Publisher : John Wiley & Sons
ISBN 13 : 0470387416
Total Pages : 920 pages
Book Rating : 4.4/5 (73 download)

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Book Synopsis Aerosol Measurement by : Pramod Kulkarni

Download or read book Aerosol Measurement written by Pramod Kulkarni and published by John Wiley & Sons. This book was released on 2011-07-12 with total page 920 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aerosol Measurement: Principles, Techniques, and Applications Third Edition is the most detailed treatment available of the latest aerosol measurement methods. Drawing on the know-how of numerous expert contributors; it provides a solid grasp of measurement fundamentals and practices a wide variety of aerosol applications. This new edition is updated to address new and developing applications of aerosol measurement, including applications in environmental health, atmospheric science, climate change, air pollution, public health, nanotechnology, particle and powder technology, pharmaceutical research and development, clean room technology (integrated circuit manufacture), and nuclear waste management.

Nanomaterials

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Publisher : Springer Science & Business Media
ISBN 13 : 1402094914
Total Pages : 459 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Nanomaterials by : Igor Linkov

Download or read book Nanomaterials written by Igor Linkov and published by Springer Science & Business Media. This book was released on 2008-12-26 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential questions regarding the risks associated with the development and use of wide-ranging technologies enabled through engineered nanomaterials. For example, with over 600 consumer products available globally, what information exists that describes their risk to human health and the environment? What en- neering or use controls can be deployed to minimize the potential environmental health and safety impacts of nanomaterials throughout the manufacturing and product lifecycles? How can the potential environmental and health benefits of nanotechnology be realized and maximized? The idea for this book was conceived at the NATO Advanced Research Workshop (ARW) on “Nanomaterials: Environmental Risks and Benefits and Emerging Consumer Products. ” This meeting – held in Algarve, Portugal, in April 2008 – started with building a foundation to harmonize risks and benefits associated with nanomaterials to develop risk management approaches and policies. More than 70 experts, from 19 countries, in the fields of risk assessment, decision-analysis, and security discussed the current state-of-knowledge with regard to nanomaterial risk and benefits. The discussion focused on the adequacy of available risk assessment tools to guide nanomaterial applications in industry and risk governance. The workshop had five primary purposes: Describe the potential benefits of nanotechnology enabled commercial products. Identify and describe what is known about environmental and human health risks of nanomaterials and approaches to assess their safety. Assess the suitability of multicriteria decision analysis for reconciling the benefits and risks of nanotechnology.

NACA Research Memorandum

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Publisher :
ISBN 13 :
Total Pages : 44 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis NACA Research Memorandum by :

Download or read book NACA Research Memorandum written by and published by . This book was released on 19?? with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Injection and Combustion of Liquid Fuels

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Publisher :
ISBN 13 :
Total Pages : 1584 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Injection and Combustion of Liquid Fuels by : A. A. Putnam

Download or read book Injection and Combustion of Liquid Fuels written by A. A. Putnam and published by . This book was released on 1957 with total page 1584 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Atmospheric Aerosols

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Publisher : CRC Press
ISBN 13 : 1498750745
Total Pages : 295 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Atmospheric Aerosols by : S Ramachandran

Download or read book Atmospheric Aerosols written by S Ramachandran and published by CRC Press. This book was released on 2018-09-03 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book includes basic knowledge and understanding on the characteristics of aerosols over the continent and oceanic regions, their composition, residence times, sinks and size distributions, and their effects in the radiative transfer and climate of Earth.

Aulton's Pharmaceutics

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Publisher : Elsevier Health Sciences
ISBN 13 : 0702042900
Total Pages : 909 pages
Book Rating : 4.7/5 (2 download)

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Book Synopsis Aulton's Pharmaceutics by : Michael E. Aulton

Download or read book Aulton's Pharmaceutics written by Michael E. Aulton and published by Elsevier Health Sciences. This book was released on 2013 with total page 909 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Pharmaceutics is the art of pharmaceutical preparations. It encompasses design of drugs, their manufacture and the elimination of micro-organisms from the products. This book encompasses all of these areas."--Provided by publisher.

Inhalation Carcinogenesis

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Publisher :
ISBN 13 :
Total Pages : 556 pages
Book Rating : 4.:/5 (43 download)

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Book Synopsis Inhalation Carcinogenesis by : J. R. Gilbert

Download or read book Inhalation Carcinogenesis written by J. R. Gilbert and published by . This book was released on 1970 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Radioactivity Analysis

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Publisher : Academic Press
ISBN 13 : 0123848733
Total Pages : 1420 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Handbook of Radioactivity Analysis by : Michael F. L'Annunziata

Download or read book Handbook of Radioactivity Analysis written by Michael F. L'Annunziata and published by Academic Press. This book was released on 2012-08-16 with total page 1420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authoritative reference providing the principles, practical techniques, and procedures for the accurate measurement of radioactivity.