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Carrier And Bioreactor Red Blood Cells For Drug Delivery And Targeting
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Book Synopsis Carrier and Bioreactor Red Blood Cells for Drug Delivery and Targeting by : John R. DeLoach
Download or read book Carrier and Bioreactor Red Blood Cells for Drug Delivery and Targeting written by John R. DeLoach and published by Pergamon Press. This book was released on 1994-01-01 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of research papers on erythrocyte encapsulation. It covers immunotargeting using erythrocyte carriers and should be useful to those exploring ways to improve drug delivery. It also covers biochemical studies on the erythrocyte and is relevant to studies of circulating bioreactors.
Book Synopsis Erythrocyte Engineering for Drug Delivery and Targeting by : Mauro Magnani
Download or read book Erythrocyte Engineering for Drug Delivery and Targeting written by Mauro Magnani and published by Springer Science & Business Media. This book was released on 2003-01-31 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Symposia on Plant Lipids, the 15th of which was held in Okazaki, Japan, in May 12-17, 2002, is held every two years and is the only international meeting in this field. The contributions from the symposium collected in this book represent the most up-to-date research results on plant lipids, including their structure, analysis, biosynthesis, regulation, physiological function, environmental aspects, and biotechnology, obtained world-wide during 2000-2002
Book Synopsis The Use of Resealed Erythrocytes as Carriers and Bioreactors by : Mauro Magnani
Download or read book The Use of Resealed Erythrocytes as Carriers and Bioreactors written by Mauro Magnani and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Until recently the only biomedical use of erythrocytes was in transfusion medicine to restore a normal oxygen delivery. The development of a technology that permits one to open and reseal erythrocytes has dramatically changed this perspective. Currently, a number of teams have shown that engineered erythrocytes can behave as circulating bioreactors for the degradation of toxic metabolites or the inactivation of xenobiotics, as drug delivery systems, as carriers of antigens of vaccinal interest, and in many others biomedical applications. The technology of opening and resealing the erythrocytes has also been used successfully to investigate several basic aspects of erythrocyte metabolism, survival, pathology, etc. Thus, researchers in this field have an extraordinary opportunity to specifically modify the erythrocytes by the introduction of enzymes that generate new metabolic abilities, antibodies that inactivate single metabolic steps, or metabolites that can influence oxygen delivery and/or other cell properties. Furthermore, the pharmacokinetics of any drug can be potentially manipulated by using the erythrocytes as a delivery system. This book, The Use of Resealed Erythrocytes, is based on the fourth meeting of the "International Society for the Use of Resealed Erythrocytes as Carriers and Bioreactors" (I. S. U. R. E. ), held in Urbino, Italy, in 1991, and examines the most recent applications and developments of this technology.
Book Synopsis Erythrocyte Engineering for Drug Delivery and Targeting by : Mauro Magnani
Download or read book Erythrocyte Engineering for Drug Delivery and Targeting written by Mauro Magnani and published by Eurekah.Com Incorporated. This book was released on 2003 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Red Blood Cells as Carriers for Drugs, Potential Therapeutic Applications by : C. Ropars
Download or read book Red Blood Cells as Carriers for Drugs, Potential Therapeutic Applications written by C. Ropars and published by Pergamon. This book was released on 1987 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hardbound. This book is a general survey of the present status of the encapsulation of xenobiotics in red blood cells and their potential therapeutic utilisation. The various participants have illustrated three general domains: 1) modification of autologous red blood cell oxygen transport properties; 2) encapsulation of enzymes and creation of circulating bioreactors; and 3) encapsulation of drugs, mainly for anticancer and antiparasitic therapy, and targeting on the reticulo-endothelial system.
Book Synopsis Erythrocytes as Drug Carriers in Medicine by : Ulrich Sprandel
Download or read book Erythrocytes as Drug Carriers in Medicine written by Ulrich Sprandel and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sixth meeting on the use of resealed annealed red blood cells was held in Irsee, Germany by the International Society for the Use of Resealed Erythrocytes (ISURE) on July 25-28, 1996. Although earlier meetings focused on the technology toward develop ment of methods and standardization for efficient, consistent encapsulation, most of the present studies now are directed toward the application use of these carrier blood cells. Basic studies now have been directed toward exploration of commercial applications. In deed, clinical trials were initiated to evaluate the dose-response curves employing L asparagenase in human patients. Also, studies have shown the use of thrombolytic agent in erythrocyte carriers with the use of human red blood cells to provide a new conceptual ap proach in thrombolytic therapy to prevent thrombosis in individuals with higher risk fac tors. For example, with the use of carrier red blood cells, the thrombolytic agents will have a greater potential of acting on clot formation without systemic activation and thus lower the risk of hemorrhage, which is always prevalent in the thrombolytic therapy.
Book Synopsis Development of Anionic Liposomal Carriers Containing Listeriolysin O and Red Blood Cell Ghosts as Plasmid DNA Delivery Platforms by : Gretchen Marie Larson
Download or read book Development of Anionic Liposomal Carriers Containing Listeriolysin O and Red Blood Cell Ghosts as Plasmid DNA Delivery Platforms written by Gretchen Marie Larson and published by . This book was released on 2004 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Polymeric Cryogels written by Oguz Okay and published by Springer. This book was released on 2014-06-02 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Brief History of Polymeric Cryogels Vladmir I. Lozinsky Basic Principles of Cryotropic Gelation Vladimir I. Lozinsky, Oguz Okay Synthesis, Structure-Property Relationships of Cryogels Oguz Okay, Vladimir I. Lozinsky Kinetic Analysis of Cryotropic Gelation of Poly(vinyl alcohol)/water Solutions by Small-Angle Neutron Scattering Claudio De Rosa, Finizia Auriemma, Rocco Di Girolamo Cryogels via UV Irradiation Technique Petar D. Petrov, Christo B. Tsvetanov Inorganic Cryogels Oleg A. Shlyakhtin Cryogels for Biotechnological Applications Bo Mattiasson Poly(vinyl alcohol) Cryogels for Biomedical Applications Wankei Wan, A. Dawn Bannerman, Lifang Yang, Helium Mak.
Book Synopsis Disposable Bioreactors by : Regine Eibl
Download or read book Disposable Bioreactors written by Regine Eibl and published by Springer. This book was released on 2009-12-02 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past five years, the immense financial pressure on the development and manufacturing of biopharmaceuticals has resulted in the increasing use and acce- ance of disposables, which are discarded after harvest and therefore intended only for single use. In fact, such disposables are implemented in all the main bioprocess production stages today and an even higher growth than those in the biopharmac- tical market is predicted (reaching double figures). Alongside disposable filter capsules, membrane chromatography units, tubing, connectors, flexible containers processing or containing fluids, freezer systems, mixers and pumps, and fully c- trolled disposable bioreactors of up to 2,000 L culture volume are already available on the market. Numerous studies highlight the advantages of disposable bioreactors and reveal their potential for simple, safe and fast seed inoculum production, process devel- ment and small as well as middle volume production (e.g. bioactive substances, viruses for vaccines and gene therapies etc.). They suggest that such disposable bioreactors (typically characterized by the cultivation chamber or bag from plastic materials) may be advantageous for plant, animal and microbial cells. Running industrial activities such as CFD-modelling, development of single-use process monitoring and control technology, and standardized film formulations are attempting to resolve the limitations of the current disposable bioreactors. These achievements, along with substantial improvements in product yield, will reduce the use of stainless steel in the biomanufacturing facilities of the future.
Book Synopsis Regenerative Pharmacology by : George J. Christ
Download or read book Regenerative Pharmacology written by George J. Christ and published by Cambridge University Press. This book was released on 2013-04-15 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: A state-of-the-art primer on the role of pharmacological sciences in regenerative medicine, for advanced students, postdoctoral fellows, and researchers.
Download or read book The Cumulative Book Index written by and published by . This book was released on 1996 with total page 2170 pages. Available in PDF, EPUB and Kindle. Book excerpt: A world list of books in the English language.
Book Synopsis Beyond the Molecular Frontier by : National Research Council
Download or read book Beyond the Molecular Frontier written by National Research Council and published by National Academies Press. This book was released on 2003-03-19 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemistry and chemical engineering have changed significantly in the last decade. They have broadened their scopeâ€"into biology, nanotechnology, materials science, computation, and advanced methods of process systems engineering and controlâ€"so much that the programs in most chemistry and chemical engineering departments now barely resemble the classical notion of chemistry. Beyond the Molecular Frontier brings together research, discovery, and invention across the entire spectrum of the chemical sciencesâ€"from fundamental, molecular-level chemistry to large-scale chemical processing technology. This reflects the way the field has evolved, the synergy at universities between research and education in chemistry and chemical engineering, and the way chemists and chemical engineers work together in industry. The astonishing developments in science and engineering during the 20th century have made it possible to dream of new goals that might previously have been considered unthinkable. This book identifies the key opportunities and challenges for the chemical sciences, from basic research to societal needs and from terrorism defense to environmental protection, and it looks at the ways in which chemists and chemical engineers can work together to contribute to an improved future.
Book Synopsis Concepts in Cell Biology - History and Evolution by : Vaidurya Pratap Sahi
Download or read book Concepts in Cell Biology - History and Evolution written by Vaidurya Pratap Sahi and published by Springer. This book was released on 2018-03-01 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses central concepts and theories in cell biology from the ancient past to the 21st century, based on the premise that understanding the works of scientists like Hooke, Hofmeister, Caspary, Strasburger, Sachs, Schleiden, Schwann, Mendel, Nemec, McClintock, etc. in the context of the latest advances in plant cell biology will help provide valuable new insights. Plants have been an object of study since the roots of the Greek, Chinese and Indian cultures. Since the term “cell” was first coined by Robert Hooke, 350 years ago in Micrographia, the study of plant cell biology has moved ahead at a tremendous pace. The field of cell biology owes its genesis to physics, which through microscopy has been a vital source for piquing scientists’ interest in the biology of the cell. Today, with the technical advances we have made in the field of optics, it is even possible to observe life on a nanoscale. From Hooke’s observations of cells and his inadvertent discovery of the cell wall, we have since moved forward to engineering plants with modified cell walls. Studies on the chloroplast have also gone from Julius von Sachs’ experiments with chloroplast, to using chloroplast engineering to deliver higher crop yields. Similarly, advances in fluorescent microscopy have made it far easier to observe organelles like chloroplast (once studied by Sachs) or actin (observed by Bohumil Nemec). If physics in the form of cell biology has been responsible for one half of this historical development, biochemistry has surely been the other.
Download or read book Corpuscles written by M. Bessis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: The shQpe of Qn erythrocyte is determined by Q delicQte equi librium of extrinsic Qnd intrinsic forces. It mQY chQnge during mQny PQtholog iCQI stQtes QS well QS du ri ng Q vQriety of ex perimentQI mQnipulQtions. Correct eVQluQtion of the fine detQi Is of the red cell shQpe thus provides i nformQtion of the g reQtest i mportQnce for the proper i nterpretQtion of the physi ology Qnd PQthophysiology of mQny Qnemic stQtes. In eXQmining red cells, the hemQtologist observes Q drop of blood spreQd on Q glQSS slide through the light microscope. This type of eXQminQtion is likely to remQin the routine tech nique of blood cytology for Q long time to come. Still, we should not forget thQt blood smeQrs Qre QrtifQcts. The smeQring flQt tens the cells completely, obliterQting mQny of their chQrQc teristics Qnd distorting others. It is therefore necessQry to conduct Q PQrQllel observQtion of cells in the I ivi ng stQte. The fundQmentQI vQlue of QII such observQtions remQins limited by the resolving power of the light microscope, which provides Q mQximum enlQrgement of one thousQnd times. To be sure, the trQnsm ission electron microscope CQn provide en IQrge ments of one mill ion times, but it IQcks penetrQti ng power, so thQt one hQS to section Q cell into five hundred slices before observi ng it. The recent Qdvent of the SCQn n i ng electron m icro scope hQS chQnged the situQtion rQd iCQlly.
Book Synopsis American Book Publishing Record by :
Download or read book American Book Publishing Record written by and published by . This book was released on 1995 with total page 1038 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Stem Cell Drugs - A New Generation of Biopharmaceuticals by : Phuc Van Pham
Download or read book Stem Cell Drugs - A New Generation of Biopharmaceuticals written by Phuc Van Pham and published by Springer. This book was released on 2018-10-25 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: This invaluable resource discusses the current revolution in stem cell-based drugs and their potential use in clinical applications. Each chapter is contributed by a pre-eminent scientist in the field. An introductory section presents current stem cell drugs and stem cell-based products and a discussion of production, quality control, mechanisms, and efficacy. Following sections include discussions on stem cell-derived microvesicles based products, and derived exosomes based products. Stem Cell Drugs - A New Generation of Biopharmaceuticals and the other books in the Stem Cells in Clinical Applications series are invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering. This groundbreaking volume is also essential reading for those researching or studying drug development or pharmaceutical science.
Book Synopsis Recent Development of Electrospinning for Drug Delivery by : Romána Zelkó
Download or read book Recent Development of Electrospinning for Drug Delivery written by Romána Zelkó and published by MDPI. This book was released on 2020-03-27 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several promising techniques have been developed to overcome the poor solubility and/or membrane permeability properties of new drug candidates, including different fiber formation methods. Electrospinning is one of the most commonly used spinning techniques for fiber formation, induced by the high voltage applied to the drug-loaded solution. With modifying the characteristics of the solution and the spinning parameters, the functionality-related properties of the formulated fibers can be finely tuned. The fiber properties (i.e., high specific surface area, porosity, and the possibility of controlling the crystalline–amorphous phase transitions of the loaded drugs) enable the improved rate and extent of solubility, causing a rapid onset of absorption. However, the enhanced molecular mobility of the amorphous drugs embedded into the fibers is also responsible for their physical–chemical instability. This Special Issue will address new developments in the area of electrospun nanofibers for drug delivery and wound healing applications, covering recent advantages and future directions in electrospun fiber formulations and scalability. Moreover, it serves to highlight and capture the contemporary progress in electrospinning techniques, with particular attention to the industrial feasibility of developing pharmaceutical dosage forms. All aspects of small molecule or biologics-loaded fibrous dosage forms, focusing on the processability, structures and functions, and stability issues, are included.
