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Cardiovascular Toxicity And Therapeutic Modalities Targeting Cardio Oncology
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Book Synopsis Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-oncology by : Imteyaz Qamar
Download or read book Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-oncology written by Imteyaz Qamar and published by Academic Press. This book was released on 2022-05-26 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-Oncology: From Basic Research to Advanced Study analyzes the emerging the field of cardio-oncology, reviewing recent advancements in the field, discussing how to monitor and treat cancer survivors for cardiotoxicity, and identifying potential cardiac side effects in novel cancer therapies. By adopting a translational approach, the book first comprehensively covers the basic science, mechanisms and concepts, which is followed by advanced state-of-art of cardio-oncology. Other sections cover tyrosine kinase inhibitors, Anthracyclines, and biomarkers in cardiotoxicity induced by chemotherapeutic drugs, noninvasive cardiovascular imaging techniques, radiotherapy induced cardiovascular, and more. Anti-cancer treatment is associated with serious cardiovascular adverse events, including arterial and pulmonary hypertension, supraventricular and ventricular arrhythmias, systolic and diastolic cardiac dysfunction and coronary artery disease. Progress in cancer therapy over the past decades improved long-term survival but increased cancer therapy-related cardiotoxicity. Both traditional chemotherapeutic agents and newer therapies have demonstrated profound cardiovascular toxicities. It is important to understand the mechanisms of these toxicities to establish strategies for the prevention and management of complications—arrhythmias, heart failure, and even death. Adopts a translational approach and comprehensively covers the basic science, mechanisms and concepts of cardio-oncology Outlines the current knowledge of biomarkers in cancer therapy-related cardiotoxicity Provides an understanding of the mechanisms of cardiovascular toxicity of various therapies that may lead to the identification of novel targets to reduce vascular complications
Book Synopsis Practical Cardio-Oncology by : Susan F. Dent
Download or read book Practical Cardio-Oncology written by Susan F. Dent and published by CRC Press. This book was released on 2019-08-30 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book takes a holistic view of the treatment of cardio-oncology patients, from evaluating those at high risk of developing cardio-toxicity, guidance for monitoring and managing patients during therapy to cardiac care of cancer survivors. Throughout, this book utilizes the latest research and guidance to offer advice on treatment strategy as well as practical elements of such as training, cardio-oncology nursing, patient education and how to establish a cardio-oncology unit. This book focuses on the practical knowledge and skills key to successful collaboration between cardiologists and oncologists to achieve the optimum cardiac care for cancer patients. Key Features Focuses on the practical elements of cardio-oncology care Outlines the importance and process of setting up a cardio-oncology unit and cardio-oncology fellowships Provides advice and guidance on the set up and common pit falls of coordinating care for cardio-oncology patients Outlines current guidelines and potential future directions for the field of cardio-oncology
Book Synopsis Cardio-Oncology by : Roberta A. Gottlieb
Download or read book Cardio-Oncology written by Roberta A. Gottlieb and published by Academic Press. This book was released on 2016-11-26 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardio-Oncology: Principles, Prevention and Management is a clinical volume that focuses on the basic science of cardio-oncology, addresses cardiotoxicity as a consequence of cancer therapy, and discusses prevention, diagnosis and management of cardiovascular disease in patients with cancer. This comprehensive volume presents unique perspectives ranging from basic science to clinical medicine in the field of cardio-oncology. It would be a valuable resource for cardiologists, oncologists, internists, and pediatricians caring for patients with cancer who have cardiovascular risk factors, as well as for cardio-oncology researchers. Covers basic science of cardio-oncology to provide readers with the necessary background Addresses cardiotoxicity related to current cancer therapeutic modalities Discusses diagnostic and management approaches of patients with underlying cardiac risk factors as well as otherwise healthy cancer patients
Book Synopsis Hot topics in Cardio-Oncology by : Valentina Mercurio
Download or read book Hot topics in Cardio-Oncology written by Valentina Mercurio and published by CRC Press. This book was released on 2022-09-01 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last years, thanks to growing advances in the field of cancer therapies, a considerable decrease in cancer mortality has been observed. Unfortunately, such therapies have shown a wide spectrum of cardiotoxicities. This book provides the readers with the latest advances and insights in the ever-expanding field of Cardio-Oncology. Specific topics discussed in the book include the potential role of inflammation in Cardio-Oncology and the description of the different manifestations of cardiotoxicities (including vascular toxicity, systemic hypertension, arrhythmias), analyzing the complex relationships between cancer and heart failure, two conditions whose prevalence increases with ageing. Furthermore, the role of biomarkers and imaging in cardio-oncology is discussed.
Book Synopsis Translational Research in Cardio-Oncology, An Issue of Heart Failure Clinics by : Ragavendra R. Baliga
Download or read book Translational Research in Cardio-Oncology, An Issue of Heart Failure Clinics written by Ragavendra R. Baliga and published by Elsevier Health Sciences. This book was released on 2022-06-23 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Heart Failure Clinics, guest editors Drs. Ragavendra R Baliga and George A. Mensah bring their considerable expertise to the topic of Translational Research in Cardio-Oncology. Top experts in the field cover key topics such as radiation-induced cardiac dysfunction; training and career development; cardiovascular imaging; CAR-T cell therapy and cardiovascular disease; and more. Contains 12 relevant, practice-oriented topics including cardio-protection of high-risk individuals; myocardial metabolism; amyloidosis; arrhythmic complications associated with cancer therapies; and more. Provides in-depth clinical reviews on translational research in cardio-oncology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Book Synopsis Cardio-Oncology by : Gretchen G. Kimmick
Download or read book Cardio-Oncology written by Gretchen G. Kimmick and published by Springer. This book was released on 2017-04-11 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Co-edited and written by an interdisciplinary team of experts in oncology and cardiology, this book is a clinically useful resource on these overlapping topics: • Cardiac complications in patients receiving cancer therapy • The treatment of cancer in patients with cardiovascular disease • The treatment of cardiovascular disease in patients with cancer When relevant to medical practice, epidemiology and basic science are also included in the discussion and each chapter is written by an oncologist and a cardiologist. Additionally, the chapters follow a similar format to make the book truly interdisciplinary, user-friendly, and clinically applicable to specialists and non-specialists who care for patients with both cancer and cardiovascular disease.
Download or read book Cardio-Oncology written by Antonio Russo and published by Springer Nature. This book was released on 2022-08-09 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of immunotherapy in oncology field has revolutionized the prognosis of many types of cancer. The immune checkpoint inhibitors target receptors whose inhibition increases the activity of immune system cells against tumor cells. In recent years, new immunotherapies have been studied and approved in a growing number of tumors including melanoma, non-small cell lung cancer (NSCLC), and renal cell cancer (RCC). This volume provides a complete and updated state-of-art review regarding the management of cardiovascular toxicities from new immunotherapies. The manuscript is divided into different sections starting from the relationship between cancer and immune system to let the reader understand the new molecular concepts under immunotherapy development. Subsequent chapters describe specifically the immunotherapy options in solid tumor treatment and the main features of the immuno-related cardiovascular complications. This volume is written by experts in the oncological and cardiovascular fields and aims to provide to clinicians who approach current cancer patients a useful tool to move through the paths of modern cardio-oncology. An important section would afford the most relevant interventions needed to manage the cardiac events, suggesting how to reduce their impact and effects on oncological outcomes. The text concludes by addressing future perspectives in the cardio-immunology field, discussing many aspects such as the early detection of cardiovascular damage and the potential role of liquid biopsy in new damage-related biomarkers discovery.
Book Synopsis Cardiovascular Complications in Cancer Therapy by : Antonio Russo
Download or read book Cardiovascular Complications in Cancer Therapy written by Antonio Russo and published by Springer. This book was released on 2018-10-04 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: This proposed text is designed to provide a useful and comprehensive resource and state-of-the-art overview to readers about vascular damage potentially induced by antineoplastic drugs. Thanks to more and more effective antineoplastic treatments the survival of cancer patients is enormously increasing, but at the same time it is increasing the burden of related cardiovascular complications that affect morbidity and mortality. On this basis a new branch of cardiology has been developed, that is Cardio-Oncology. The aim is to prevent cardiovascular complications related to cancer therapy and to facilitate and avoid interruption of antineoplastic drugs due to the occurrence of cardiovascular damage. An increasing attention has been given to cardiac damage, while, until today, vascular complications have been poorly evaluated. The aim of this book is to focus on vascular complications related to cancer treatment, to guide the clinician at facing, during his every day practice, cardiovascular toxicity in cancer and hematologic patients. The proposed sections of the book have been structured to review the molecular mechanisms underlying vascular damage induced by new and old treatments, to describe the various manifestations of vascular disease that may range from artery to venous disease (including coronary artery disease, peripheral arterial disease, venous thromboembolism and pulmonary hypertension), and to provide advice to monitor patients undergoing onco-hematologic treatments in order to prevent and eventually manage vascular damage.This book will address resident and fellow physicians, medical oncologists, cardiologists, general practitioners and all those who take care of these patients.All invited authors will be recognized experts in their field, and leading international researchers on these topics. The editor has worked with these expert colleagues on a variety of other projects. The authors will provide their manuscript according to current literature and clinical research studies. The book does not seek to duplicate or replace other current resources. Rather, it will create a comprehensive yet concise resource on this emerging topic that is not adequately covered by any current literature.
Book Synopsis Cardio-Oncology: From Bench to Bedside by : Jun-ichi Abe
Download or read book Cardio-Oncology: From Bench to Bedside written by Jun-ichi Abe and published by Frontiers Media SA. This book was released on 2019-05-17 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardio-oncology is a medical subspecialty concerned with the diagnosis and treatment of cardiovascular disease (CVD) and organ failure mediated by micro- to macro-circulation defects in cancer patients and survivors. The risk of CVD in cancer survivors is eight times higher than the general population, and the relative risk of coronary artery disease and heart failure (HF) is 10 times and 15 times higher, respectively, compared to their siblings without cancer. It is important to note that cancer treatments including chemotherapy and radiation can lead to both short- (< 1 year) and long-term (> 5 years) cardiovascular complications. Previously, Dr. Edward T.H. Yeh initiated the MD Anderson Practice (MAP) project, and published 16 MAPs to provide the current best practice we considered at UT MD Anderson. As shown in these MAPs, one of the key issues of cardio-oncology practice and science is how we can allow cancer patients to receive maximum and uninterrupted treatments for cancer while protecting them from cancer therapy-mediated cardiovascular complications. Therefore, it is crucial to understand not only pathophysiology of CVD, but also mechanistic insights of how each cancer treatment can control cancer growth and metastasis. Without having the profound knowledge in the pathophysiological, clinical and epidemiologic aspects of cardiovascular complications of existing cancer therapy, it is impossible to establish the strong evidence-based strategies and approaches for both short- and long-term cardiovascular complications after cancer treatment. In addition, we believe that cardio-oncology science should not be restricted to deal with the side effects of each specific cancer drug, because many common cardiovascular phenotypes among the different cancer treatments are also observed. This Research Topic provides a comprehensive overview from both of the current research and practice, and a platform for obtaining the logical and up-to-date treatment and prevention of CVD in cancer patients and survivors.
Book Synopsis Cardio-Oncology, An Issue of Cardiology Clinics by : Monika Jacquelin Leja
Download or read book Cardio-Oncology, An Issue of Cardiology Clinics written by Monika Jacquelin Leja and published by Elsevier Health Sciences. This book was released on 2019-10-11 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Cardiology Clinics, guest edited by Dr. Monika Jacquelina Leja, will focus on Cardio-Oncology. Topics include, but are not limited to, Anthracycline Cardiomyopathy in Cancer Patients, Common Vascular Toxicities of Cancer Therapies, Cardiotoxicity of Immune Therapy, 5 FU Related Cardiotoxicity, Trastuzumab Induced Cardiotoxicity, Echocardiography Imaging of Cardiotoxicity, MRI Imaging of Cardiotoxicity, Cardiomyopathy Prevention in Cancer Patients, Radiation Related Cardiovascular Disease, Electrophysiology in Cardio-Oncology, Cardiac Interventional Procedures in Cardio-Oncology Patients, Diagnosis and Treatment of Amyloid Related to Myeloid Dyscrasias, Carcinoid Heart Disease, Cardiac Tumors, Cardiovascular Toxicities in Pediatric Cancer Survivors, and Developing a Cardio-Oncology Practice Nuts and Bolts: Coding and Billing.
Book Synopsis Cardiovascular Toxicities of Breast Cancer Treatment: Emerging Issues in Cardio-Oncology by : Sharad Goyal
Download or read book Cardiovascular Toxicities of Breast Cancer Treatment: Emerging Issues in Cardio-Oncology written by Sharad Goyal and published by Frontiers Media SA. This book was released on 2016-05-20 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer and cardiovascular disease (CVD) are the two most common causes of mortality and morbidity worldwide. The incidence of both cancer and cardiovascular disease increases with age. With increased life expectancy, the burden of both these diseases will increase substantially in coming years. Patients with CVD share multiple common risk factors and lifestyle behaviors in addition to frequently suffering from multiple comorbid conditions. Tobacco use, hypertension, high cholesterol, diabetes, physical inactivity, and poor nutrition are all established risk factors of heart disease. Patients with diseases such as breast cancer may develop CVD from treatment, such as use of chemotherapy and RT. Effects on the heart are a potentially significant and serious clinical problem in radiation therapy treatment of breast cancer. Over the course of the past 50 years, there have been great advances in the delivery of RT due to the development of new techniques, beam energy, improvement in imaging modalities, and development of image registration strategies. It is hypothesized that cardiac damage from RT is correlated to the dose absorbed by the heart and differs between left- and right-breast radiotherapy. The damage to cardiac micro- and macro-vasculature is the pathophysiological cause of RT-related heart disease. Given the growing clinical relevance of cardio-oncology, this Frontiers in Oncology Research Topic provides a venue for disseminating focused reviews and cutting edge research in this quickly growing field. We encourage submission of original papers and reviews dealing with cardiac toxicity after breast cancer treatment, motion management to reduce cardiac exposure, imaging to evaluate potential cardiac toxicities and primary prevention of cardiac disease in the breast cancer patient.
Book Synopsis Anticancer Treatments and Cardiotoxicity by : Patrizio Lancellotti
Download or read book Anticancer Treatments and Cardiotoxicity written by Patrizio Lancellotti and published by Academic Press. This book was released on 2016-11-11 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anticancer Treatments and Cardiotoxicity: Mechanisms, Diagnostic and Therapeutic Interventions presents cutting edge research on the adverse cardiac effects of both radiotherapy and chemotherapy, brought together by leaders in the field. Cancer treatment-related cardiotoxicity is the leading cause of treatment-associated mortality in cancer survivors and is one of the most common post-treatment issues among survivors of adult cancer. Early detection of the patients prone to developing cardiotoxicity, taking in to account the type of treatment, history and other risk factors, is essential in the fight to decrease cardiotoxic mortality. This illustrated reference describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment. In addition, new guidelines on imaging for the screening and monitoring of these patients are also presented. Anticancer Treatments and Cardiotoxicity is an essential reference for those involved in the research and treatment of cardiovascular toxicity. Provides algorithms essential for the use of imaging, and biomarkers for the screening and monitoring of patients Written by world-leading experts in the field of cardiotoxicity Includes high-quality images, case studies, and test questions Describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment
Book Synopsis Clinical Cardio-oncology E-Book by : Joerg Herrmann
Download or read book Clinical Cardio-oncology E-Book written by Joerg Herrmann and published by Elsevier Health Sciences. This book was released on 2016-10-19 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Cardio-oncology is a comprehensive, clinically focused title for cardiologists, oncologists, and specialists in cardio-oncology programs who need up-to-date knowledge about the cardiovascular effects of cancer treatment, especially on long-term cancer survivors. This brand-new resource covers the implementation of cardio-oncology into your practice, while a strong focus on patient management offers helpful information on coordinating care before, during, and after therapy. Its highly organized four-section format allows readers to quickly and easily locate relevant information. Comprised of four sections for quick and easy reference: Oncology and Hematology Principles; Cardiac Complications from Cancer Therapy; Coordination of Care; and Cardio-oncology in Practice. Provides expert wisdom from cardio-oncology authorities around the world, as well as consultation and perspectives from pioneers in the field of oncology. Highlights the principles of cancer therapies, including radiation and tumor therapy, as well as pre-, intra-, and post-therapy cardiology evaluation. Boasts chapters on implementing cardio-oncology into practice: primary cancer centers, comprehensive referral centers, group practices, and educational needs and goals for fellowship programs. Advises on how to coordinate care for the patient at every stage of treatment (pre-therapy, during therapy, after therapy, and end-of-life). Presents detailed information on various cardiac complications from cancer therapy, such as cardiomyopathy, vascular disease, arrhythmias, and hypertension. Teaches the principles of oncology and hematology with coverage of different therapy types and cardiac tumors. Includes a comprehensive drug guide.
Book Synopsis Cardiac Management of Oncology Patients by : Gonzalo Baron Esquivias
Download or read book Cardiac Management of Oncology Patients written by Gonzalo Baron Esquivias and published by Springer. This book was released on 2015-05-25 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed for clinical cardiologists and other physicians working with cardiac patients, where specific specialized teams of cardio-oncologists are not available and who are called to perform a clinical consultation to evaluate both the cardiac condition and the eligibility for chemotherapy or radiotherapy treatment, and to evaluate if a cancer treatment produces toxic effects on a patient treated with chemo or radiotherapy and if appearance of new symptoms is due to this treatment. In recent years, progress in oncologic therapy has resulted in important developments and the prognostic improvement of patients with malignancy. The cornerstone of chemotherapy are the anthracyclines (and the analogue Mitoxantrone), that are direct cellular toxic agents and that are among the most powerful anti-neoplastic drugs, but their cardiac toxicity is well known. Significant breakthroughs in cancer therapy have also been achieved with the introduction of signalling inhibitors, such as VEGF inhibitors, HERB2 inhibitors or TK inhibitors used alone or in combination with direct cellular toxic drugs. However, these signalling inhibitors may interact also with cardiovascular signalling and therefore may have functional or structural effects on the myocardium. This can be permanent or reversible, with impairment of the global conditions and important side effects, and increase both morbidity and mortality and worsening of quality of life. Chemotherapy and radiotherapy can have acute detrimental effects that can be present for years after treatment and that can lead to cardiac consequences also after long periods of no clinic sequelae. Patient numbers with cancer problems will dramatically increase in the next years and thus every cardiologist will need to have the correct information and the skills to manage these situations in the correct way. This book will provide these tools for them.
Book Synopsis The Washington Manual of Cardio-Oncology by : Daniel J Lenihan
Download or read book The Washington Manual of Cardio-Oncology written by Daniel J Lenihan and published by Lippincott Williams & Wilkins. This book was released on 2021-12-09 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experts in cardiovascular disease, hematology, and oncology, The Washington Manual® of Cardio-Oncology: A Practical Guide for Improved Cancer Survivorship is a clinically relevant, easy-to-use primer on the detection, management, and improved cardiovascular-based patient outcomes in adults undergoing treatment for cancer or who have previously survived cancer therapy. Edited by Drs. Daniel J. Lenihan, Joshua D. Mitchell, and Kathleen W. Zhang, this concise yet comprehensive manual provides high-yield information that reflects today’s advances in risk stratification, early diagnosis, and treatment of cardiovascular disease—all in an easy-access, concisely bulleted format for on-the-go reference.
Book Synopsis Manual of Cardio-oncology by : Chiara Lestuzzi
Download or read book Manual of Cardio-oncology written by Chiara Lestuzzi and published by Springer. This book was released on 2017-10-13 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise and handy manual provides straightforward, up-to-date guidance for cardiologists and other practitioners on the management of cancer patients with cardiac problems, whether they be due to the cancer itself or to antineoplastic treatment. Detailed attention is devoted to the various forms of cardiotoxicity associated with chemotherapy and radiotherapy. The drugs commonly responsible for each toxicity are identified and clear advice is offered on monitoring techniques and treatment approaches. In addition, the issue of cardiotoxicity due to cancer treatment in particular patient groups – children, the elderly, and those with pre-existing cardiac disease – is addressed separately, with guidance on when and how antineoplastic (and/or cardiological) treatments should be modified. Further sections describe the correct responses to cardiac problems secondary to the cancer itself, including thromboembolic disorders and electrolyte imbalances, and the diagnosis, treatment, and follow-up of cardiac tumors. A closing section considers how to improve cooperation between oncologists, cardiologists, and general practitioners to ensure that cancer patients’ cardiovascular needs are met in a multidisciplinary approach.
Book Synopsis Cardio-oncology Related to Heart Failure, An Issue of Heart Failure Clinics, E-Book by : Daniel J. Lenihan
Download or read book Cardio-oncology Related to Heart Failure, An Issue of Heart Failure Clinics, E-Book written by Daniel J. Lenihan and published by Elsevier Health Sciences. This book was released on 2017-03-11 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of the Heart Failure Clinics of North America, guest edited by Drs. Daniel Lenihan and Douglas Sawyer, will cover several aspects of Cardio-oncology Related to Heart Failure. Subjects discussed in the volume include, but are not limited to: Proteasome Inhibitors as a potential cause of Heart Failure; EGFR target based therapy; Amyloidosis; How to manage Heart Failure in a patient with cancer; Advanced HF/Txp; Epidemiology and common risk factors; Pediatric Considerations; Alternative biomarkers for combined biology; How to develop a Cardio-Oncology Clinic; and How to structure a Cardio-Oncology fellowship program, among others.
