Cardiac Ischemia From Injury To Protection

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Cardiac Ischemia: From Injury to Protection

Author : Bohuslav Ost'ádal
Publisher : Springer Science & Business Media
ISBN 13 : 147573025X
Total Pages : 198 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Cardiac Ischemia: From Injury to Protection by : Bohuslav Ost'ádal

Download or read book Cardiac Ischemia: From Injury to Protection written by Bohuslav Ost'ádal and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac Ischemia: From Injury to Protection has been divided into six parts. The first part describes the differences between hypoxia and ischemia, animal models, the effects of ischemia on myocardial function and metabolism, and the electrophysiological consequences of ischemia. The second part deals with the mechanisms of cardiomyocyte death in ischemia, structural aspects of irreversible ischemic injury, necrosis and apoptosis of cardiac cells, the role of calcium, and the concept of calcium antagonism. The third chapter is a brief description of reperfusion injury, its clinical relevance, and possible prevention. The fourth part summarizes changes in myocardial vasculature during ischemia and reperfusion. The fifth part is the survey of two main possibilities for increasing cardiac resistance to ischemia and hypoxia, i.e. long-lasting adaptation to chronic hypoxia and short-lasting preconditioning. The last part of the book deals with comparative and ontogenetic aspects of cardiac sensitivity to oxygen deprivation; this chapter also summarizes the ontogenetic differences and limitations in endogenous and exogenous protection of the ischemic/hypoxic heart.

Cardiac Ischemia: From Injury to Protection

Author : Bohuslav Ost'ádal
Publisher : Springer
ISBN 13 : 9781441951052
Total Pages : 173 pages
Book Rating : 4.9/5 (51 download)

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Book Synopsis Cardiac Ischemia: From Injury to Protection by : Bohuslav Ost'ádal

Download or read book Cardiac Ischemia: From Injury to Protection written by Bohuslav Ost'ádal and published by Springer. This book was released on 2010-12-02 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac Ischemia: From Injury to Protection has been divided into six parts. The first part describes the differences between hypoxia and ischemia, animal models, the effects of ischemia on myocardial function and metabolism, and the electrophysiological consequences of ischemia. The second part deals with the mechanisms of cardiomyocyte death in ischemia, structural aspects of irreversible ischemic injury, necrosis and apoptosis of cardiac cells, the role of calcium, and the concept of calcium antagonism. The third chapter is a brief description of reperfusion injury, its clinical relevance, and possible prevention. The fourth part summarizes changes in myocardial vasculature during ischemia and reperfusion. The fifth part is the survey of two main possibilities for increasing cardiac resistance to ischemia and hypoxia, i.e. long-lasting adaptation to chronic hypoxia and short-lasting preconditioning. The last part of the book deals with comparative and ontogenetic aspects of cardiac sensitivity to oxygen deprivation; this chapter also summarizes the ontogenetic differences and limitations in endogenous and exogenous protection of the ischemic/hypoxic heart.

Myocardial Protection

Author : Tomas A. Salerno
Publisher : John Wiley & Sons
ISBN 13 : 1405178434
Total Pages : 344 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Myocardial Protection by : Tomas A. Salerno

Download or read book Myocardial Protection written by Tomas A. Salerno and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myocardial protection is regarded as one of the most important, yet also most controversial aspects of cardiac surgery. There has been considerable improvement in myocardial protection strategies over recent years, utilising a variety of new approaches to treat cardiac diseases, and this text is intended to embrace the state of the art in this field. The book summarises the state of knowledge on all aspects of myocardial protection, including the latest in the treatment of cardiac diseases, robotics, pediatric surgery and the treatment of cardiac failure. Robotic surgery, valvular surgery, pediatric surgery and coronary surgery are all covered by renowned experts, producing a comprehensive, forward-looking view of the field of myocardial protection. This book should function to update physicians and surgeons interested in the field of cardiac surgery on the current state of knowledge on myocardial protection.

Ischemic Myocardial Injury and Protection: From Bench to Bedside

Author : Hui Gong
Publisher : Frontiers Media SA
ISBN 13 : 2889763587
Total Pages : 155 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Ischemic Myocardial Injury and Protection: From Bench to Bedside by : Hui Gong

Download or read book Ischemic Myocardial Injury and Protection: From Bench to Bedside written by Hui Gong and published by Frontiers Media SA. This book was released on 2022-06-07 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Myocardial Ischemia: Mechanisms, Reperfusion, Protection

Author : Morris Karmazyn
Publisher : Birkhäuser
ISBN 13 : 3034889887
Total Pages : 508 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Myocardial Ischemia: Mechanisms, Reperfusion, Protection by : Morris Karmazyn

Download or read book Myocardial Ischemia: Mechanisms, Reperfusion, Protection written by Morris Karmazyn and published by Birkhäuser. This book was released on 2013-03-12 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myocardial ischemia and subsequent reperfusion of the ischemic myocardium represent complex phenomena encompassing numerous physiological processes. This book aims at enhancing our understanding of these processes and stresses recent important developments in this very active area of research. The concise, state-of-the-art reviews cover recent advances in many fields important to the area of myocardial ischemia and reperfusion including physiology, pathology, pharmacology, biochemistry and molecular biology with reference to clinical relevance and applicability of these findings. Major areas which are highlighted include vascular mechanisms resulting in myocardial ischemia, cellular events in the ischemic, postinfarcted and reperfused myocardium as well as new exciting developments in cardiac protection that involve both novel pharmacological approaches as well as endogenous cardioprotective mechanisms such as preconditioning. Aimed at both the basic and clinical cardiovascular investigator, the book comprehensively reviews the rapid progress made in recent years in understanding the etiology of myocardial ischemia and reperfusion. It will further serve as an authoritative reference for all those interested in learning about the important developments in the treatment of myocardial ischemic and reperfusion disorders.

The Ischemic Heart

Author : Seibu Mochizuki
Publisher : Springer
ISBN 13 : 0585398445
Total Pages : 601 pages
Book Rating : 4.5/5 (853 download)

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Book Synopsis The Ischemic Heart by : Seibu Mochizuki

Download or read book The Ischemic Heart written by Seibu Mochizuki and published by Springer. This book was released on 2007-11-23 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past three decades, impressive progress in the field of pathogenesis, prevention and therapy of ischemic heart disease has resulted in a marked decline in mortality in the Western World. However, the incidence of this devastating disease is on the rise in developing countries. The Ischemic Heart is based upon a recent symposium in Tokyo on the subject. This volume is organized into two sections: (i) Pathophysiologic Mechanisms of Ischemia-Reperfusion Injury and (ii) Preconditioning and Protection of Ischemia-Reperfusion Injury, and contains up-to-date information concerning the current concepts of ischemia-reperfusion injury, the sequence of events resulting in the loss of contractile dysfunction, and mechanisms of cardioprotection by several drugs as well as the role of ischemic preconditioning in attenuating problems associated with ischemia-reperfusion injury.

Handbook of Cardiac Anatomy, Physiology, and Devices

Author : Paul A. Iaizzo
Publisher : Springer
ISBN 13 : 331919464X
Total Pages : 817 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Handbook of Cardiac Anatomy, Physiology, and Devices by : Paul A. Iaizzo

Download or read book Handbook of Cardiac Anatomy, Physiology, and Devices written by Paul A. Iaizzo and published by Springer. This book was released on 2015-11-13 with total page 817 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow’s generation of life-saving cardiac devices.

Myocardial Ischemia and Preconditioning

Author : Naranjan S. Dhalla
Publisher : Springer Science & Business Media
ISBN 13 : 1461503558
Total Pages : 564 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Myocardial Ischemia and Preconditioning by : Naranjan S. Dhalla

Download or read book Myocardial Ischemia and Preconditioning written by Naranjan S. Dhalla and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current evidence suggests that the ischemic preconditioning response is a multi-factorial process consisting of an initial early trigger, an intermediate mediator, and an end effector. Each of these steps in is now its own intense area of investigation. The need to render the heart ischemic for a brief period to invoke the preconditioning response is currently the major factor limiting clinical application of this powerful cardioprotective strategy. Recent research efforts have utilized brief exposures to pharmacological agents, in lieu of a brief preconditioning ischemia, to trigger/mimic the ischemic preconditioning-induced response. The World Heart Congress held in Winnipeg in July 2001 provided a forum for the presentation of new insights into the basic mechanisms of ischemia and reperfusion injury, as well as novel strategies to protect the heart from cell death, ventricular arrhythmias, and contractile dysfunction. Many pioneers in the fields of ischemia-reperfusion injury and preconditioning-induced protection presented there and the chapters in this book represent selected papers from these symposia.

Interactive Phenomena in the Cardiac System

Author : S. Sideman
Publisher : Springer Science & Business Media
ISBN 13 : 1461529468
Total Pages : 417 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Interactive Phenomena in the Cardiac System by : S. Sideman

Download or read book Interactive Phenomena in the Cardiac System written by S. Sideman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cardiac system represents one of the most exciting challenges to human ingenuity. Critical to our survival, it consists of a tantalizing array of interacting phenomena, from ionic transport, membrane channels and receptors through cellular metabolism, energy production to fiber mechanics, microcirculation, electrical activation to the global, clinically observed, function, which is measured by pressure, volume, coronary flow, heart rate, shape changes and responds to imposed loads and pharmaceutical challenges. It is a complex interdisciplinary system requiring the joint efforts of the life sciences, the exact sciences, engineering and technology to understand and control the pathologies involved. The Henry Goldberg Workshops were set up to address these multivariable, multidisciplinary challenges. Briefly, our goals are: To encourage international cooperation and foster interdisciplinary interaction between scientists from the different areas of cardiology; to relate microscale cellular phenomena to the global, clinically manifested cardiac function; to relate conceptual modeling and quantitative analysis to experimental and clinical data; to gain an integrated view of the various interacting parameters, identify missing links, catalyze new questions, and lead to better understanding of the cardiac system. The outstanding success of past workshops has encouraged their continuation. The first Henry Goldberg Workshop, held in Haifa in 1984, introduced the concept of interaction between mechanics, electrical activation, perfusion and metabolism, emphasizing imaging in the clinical environment. The second Workshop, in 1985, discussed the same parameters with a slant towards the control aspects.

Cardioprotection

Author : Derek Hausenloy
Publisher : OUP Oxford
ISBN 13 : 0191575488
Total Pages : 144 pages
Book Rating : 4.1/5 (915 download)

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Book Synopsis Cardioprotection by : Derek Hausenloy

Download or read book Cardioprotection written by Derek Hausenloy and published by OUP Oxford. This book was released on 2009-08-20 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronary heart disease (CHD) is the leading cause of death worldwide with 3.8 million men and 3.4 million women dying each year. Cardioprotection refers to the prevention of CHD and the clinical improvement in patients suffering from cardiovascular problems. This book focuses on the role of cardioprotection in surgery and the use of pharmacological therapies such as ACE-inhibitors, statins and beta-blockers in order to reduce the myocardial injury sustained by the patient and the significant risk of morbidity and mortality. It includes new cardioprotective strategies aimed at improving the clinical outcomes of patients in these settings, as well as current well-established methods for reducing myocardial injury in acute coronary syndrome patients.

Cardiac Diseases

Author : David C. Gaze
Publisher : BoD – Books on Demand
ISBN 13 : 1839681616
Total Pages : 356 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Cardiac Diseases by : David C. Gaze

Download or read book Cardiac Diseases written by David C. Gaze and published by BoD – Books on Demand. This book was released on 2021-07-28 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the latest book in a series of cardiovascular-related texts from IntechOpen Publishing. The present volume considers general aspects of cardiac disease and is divided into three distinct sections covering cardiac risk, cardiorenal pathology, and novel interventional surgical techniques. The chapters offer insight into the current state of the art with respect to the risks of developing cardiovascular diseases, maintenance of patent vascular access in patients with the cardiorenal syndrome, and a plethora of novel interventional technologies all aimed at salvaging damaged tissue and improving prognosis and reducing mortality. This volume of 18 chapters is intended for general medical and biomedical students at both undergraduate and postgraduate level. It also offers insightful updates on recent advances in the understanding of the pathophysiology of cardiac diseases and the new techniques added to the medical armamentarium to improve the outcomes and prevent mortality and would be of interest to those working in academia and healthcare science.

Mechanisms of Vascular Disease

Author : Robert Fitridge
Publisher : University of Adelaide Press
ISBN 13 : 1922064009
Total Pages : 589 pages
Book Rating : 4.9/5 (22 download)

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Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge

Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Myocardial Protection

Author : Derek M. Yellon
Publisher :
ISBN 13 :
Total Pages : 232 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Myocardial Protection by : Derek M. Yellon

Download or read book Myocardial Protection written by Derek M. Yellon and published by . This book was released on 1992 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: An insight into the theories and controversies regarding myocardial reperfusion and reperfusion-induced injury. The ideas presented advance the understanding of the relationship of reperfusion injury to the beneficial effects of restoring coronary flow to the myocardium after an ischemic insult.

Ischemia-Reperfusion Injury in Cardiac Surgery

Author : Friedhelm Beyersdorf
Publisher : CRC Press
ISBN 13 :
Total Pages : 250 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Ischemia-Reperfusion Injury in Cardiac Surgery by : Friedhelm Beyersdorf

Download or read book Ischemia-Reperfusion Injury in Cardiac Surgery written by Friedhelm Beyersdorf and published by CRC Press. This book was released on 2001 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac surgery is associated with ischemia and reperfusion injury for most of the operations performed. During the last decades, major improvements have been done in reducing both ischemic and reperfusion injury and therefore improving the quality of the operation. This book summarizes the newest developments in this field. In addition, specific comments are made concerning the surgical application of the fields in all kinds of operation, including routine cases as well as complex procedures. The reader will gain a detailed insight regarding how to protect patients best during routine cardiac procedures (coronary artery revascularization and valve replacement) as well as prolonged, technically demanding operations

Myocardial Ischemia

Author : Dennis V. P. Cokkinos
Publisher : Springer Science & Business Media
ISBN 13 : 9780387286570
Total Pages : 228 pages
Book Rating : 4.2/5 (865 download)

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Book Synopsis Myocardial Ischemia by : Dennis V. P. Cokkinos

Download or read book Myocardial Ischemia written by Dennis V. P. Cokkinos and published by Springer Science & Business Media. This book was released on 2006 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tremendous progress has been made in understanding the pathophysiology of ischemic heart disease. As a result, new therapeutic approaches for protecting the heart from ischemic injury are in development. This volume will highlight issues concerning basic mechanisms of ischemia-reperfusion injury in relation to potential therapeutic strategies.

Myocardial Ischemia: New Insights for the Healthcare Professional: 2012 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464975116
Total Pages : 60 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Myocardial Ischemia: New Insights for the Healthcare Professional: 2012 Edition by :

Download or read book Myocardial Ischemia: New Insights for the Healthcare Professional: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-10 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myocardial Ischemia: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Myocardial Ischemia in a concise format. The editors have built Myocardial Ischemia: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Myocardial Ischemia in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Myocardial Ischemia: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Management of Myocardial Reperfusion Injury

Author : Juan Carlos Kaski
Publisher : Springer Science & Business Media
ISBN 13 : 1849960194
Total Pages : 311 pages
Book Rating : 4.8/5 (499 download)

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Book Synopsis Management of Myocardial Reperfusion Injury by : Juan Carlos Kaski

Download or read book Management of Myocardial Reperfusion Injury written by Juan Carlos Kaski and published by Springer Science & Business Media. This book was released on 2012-07-20 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Much has been written about reperfusion injury in the past decade but unfortunately the information has been generally presented in the form of original specialist papers and little if any integral publication exists on the topic, summarising and analysing the clinical impact of the condition and its management. The pathophysiology and molecular mechanisms of reperfusion injury are complex and, regarding diagnosis, individual diagnostic techniques have been proposed but without a proper assessment of the relative values of these methods. A publication dealing with integral diagnostic strategies would be welcome by the managing physician. Management of the condition is also problematic, as strategies that appear to work in the experimental models do not translate into beneficial interventions in patients. There is a need for these issues to be addressed and discussed in a monographic fashion. Management of Myocardial Reperfusion Injury will tackle these issues in a modern and systematic way and the information will be delivered in a fashion that will be appealing to the reader.