Carbonic Anhydrase Inhibitor Anticonvulsants—Advances in Research and Application: 2012 Edition

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Publisher : ScholarlyEditions
ISBN 13 : 1481631071
Total Pages : 26 pages
Book Rating : 4.4/5 (816 download)

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Book Synopsis Carbonic Anhydrase Inhibitor Anticonvulsants—Advances in Research and Application: 2012 Edition by :

Download or read book Carbonic Anhydrase Inhibitor Anticonvulsants—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 26 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbonic Anhydrase Inhibitor Anticonvulsants—Advances in Research and Application: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Carbonic Anhydrase Inhibitor Anticonvul in a compact format. The editors have built Carbonic Anhydrase Inhibitor Anticonvulsants—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Carbonic Anhydrase Inhibitor Anticonvul in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Carbonic Anhydrase Inhibitor Anticonvulsants—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Carbonic Anhydrase Inhibitor Anticonvulsants—Advances in Research and Application: 2012 Edition

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Publisher : ScholarlyEditions
ISBN 13 : 1481631063
Total Pages : 34 pages
Book Rating : 4.4/5 (816 download)

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Book Synopsis Carbonic Anhydrase Inhibitor Anticonvulsants—Advances in Research and Application: 2012 Edition by :

Download or read book Carbonic Anhydrase Inhibitor Anticonvulsants—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbonic Anhydrase Inhibitor Anticonvulsants—Advances in Research and Application: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Carbonic Anhydrase Inhibitor Anticonvul in a compact format. The editors have built Carbonic Anhydrase Inhibitor Anticonvulsants—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Carbonic Anhydrase Inhibitor Anticonvul in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Carbonic Anhydrase Inhibitor Anticonvulsants—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Hydro-Lyases—Advances in Research and Application: 2012 Edition

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Publisher : ScholarlyEditions
ISBN 13 : 1464999163
Total Pages : 174 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Hydro-Lyases—Advances in Research and Application: 2012 Edition by :

Download or read book Hydro-Lyases—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hydro-Lyases—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Hydro-Lyases. The editors have built Hydro-Lyases—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Hydro-Lyases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Hydro-Lyases—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Lyases: Advances in Research and Application: 2011 Edition

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Publisher : ScholarlyEditions
ISBN 13 : 1464939594
Total Pages : 49 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Lyases: Advances in Research and Application: 2011 Edition by :

Download or read book Lyases: Advances in Research and Application: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 49 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lyases: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Lyases in a concise format. The editors have built Lyases: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Lyases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Lyases: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Advances in Blood Research and Application: 2013 Edition

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Publisher : ScholarlyEditions
ISBN 13 : 1481681850
Total Pages : 636 pages
Book Rating : 4.4/5 (816 download)

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Book Synopsis Advances in Blood Research and Application: 2013 Edition by :

Download or read book Advances in Blood Research and Application: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Blood Research and Application / 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Plasma. The editors have built Advances in Blood Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Plasma in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Blood Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

In-cell NMR Spectroscopy

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Publisher : Royal Society of Chemistry
ISBN 13 : 1839160934
Total Pages : 322 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis In-cell NMR Spectroscopy by : Yutaka Ito

Download or read book In-cell NMR Spectroscopy written by Yutaka Ito and published by Royal Society of Chemistry. This book was released on 2019-12-09 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: In-cell NMR spectroscopy is a relatively new field. Despite its short history, recent in-cell NMR-related publications in major journals indicate that this method is receiving significant general attention. This book provides the first informative work specifically focused on in-cell NMR. It details the historical background of in-cell NMR, host cells for in-cell NMR studies, methods for in-cell biological techniques and NMR spectroscopy, applications, and future perspectives. Researchers in biochemistry, biophysics, molecular biology, cell biology, structural biology as well as NMR analysts interested in biological applications will all find this book valuable reading.

Carbonic Anhydrase

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Publisher : CRC Press
ISBN 13 : 1134400152
Total Pages : 588 pages
Book Rating : 4.1/5 (344 download)

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Book Synopsis Carbonic Anhydrase by : Claudiu T. Supuran

Download or read book Carbonic Anhydrase written by Claudiu T. Supuran and published by CRC Press. This book was released on 2004-05-27 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbonic Anhydrase: Its Inhibitors and Activators provides a state-of-the-art overview of the latest developments and challenges in carbonic anhydrase research. Authors describe the mechanisms of action of specific inhibitors in relation to physiological function, and present previously unpublished research on CA activators. Written by a team of in

Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications

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Publisher : Springer Science & Business Media
ISBN 13 : 9400773595
Total Pages : 429 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications by : Susan C. Frost

Download or read book Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications written by Susan C. Frost and published by Springer Science & Business Media. This book was released on 2013-10-22 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of carbonic anhydrase has spanned multiple generations of scientists. Carbonic anhydrase was first discovered in 1932 by Meldrum and Roughton. Inhibition by sulfanilamide was shown in 1940 by Mann and Keilin. Even Hans Krebs contributed to early studies with a paper in 1948 showing the relationship of 25 different sulfonamides to CA inhibition. It was he who pointed out the importance of both the charged and uncharged character of these compounds for physiological experiments. The field of study that focuses on carbonic anhydrase (CA) has exploded in recent years with the identification of new families and isoforms. The CAs are metalloenzymes which are comprised of 5 structurally different families: the alpha, beta, gamma, and delta, and epsilon classes. The alpha class is found primarily in animals with several isoforms associated with human disease. The beta CAs are expressed primarily in plants and are the most divergent. The gamma CAs are the most ancient. These are structurally related to the beta CAs, but have a mechanism more similar to the alpha CAs. The delta CAs are found in marine algae and diflagellates. The epsilon class is found in prokaryotes in which it is part of the carboxysome shell perhaps supplying RuBisCO with CO2 for carbon fixation. With the excitement surrounding the discovery of disease-related CAs, scientists have redoubled their efforts to better understand structure-function relationships, to design high affinity, isotype-specific inhibitors, and to delineate signaling systems that play regulatory roles over expression and activity. We have designed the book to cover basic information of mechanism, structure, and function of the CA families. The authors included in this book bring to light the newest data with regard to the role of CA in physiology and pathology, across phylums, and in unique environmental niches.

Drug-Induced Liver Injury

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Publisher : Academic Press
ISBN 13 : 0128173173
Total Pages : 288 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Drug-Induced Liver Injury by :

Download or read book Drug-Induced Liver Injury written by and published by Academic Press. This book was released on 2019-07-13 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series

Concepts and Principles of Pharmacology

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Publisher : Springer Nature
ISBN 13 : 3030353621
Total Pages : 466 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Concepts and Principles of Pharmacology by : James E. Barrett

Download or read book Concepts and Principles of Pharmacology written by James E. Barrett and published by Springer Nature. This book was released on 2019-12-24 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.

New Antiepileptic Drugs

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Publisher : Elsevier Publishing Company
ISBN 13 :
Total Pages : 216 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis New Antiepileptic Drugs by : Francesco Pisani

Download or read book New Antiepileptic Drugs written by Francesco Pisani and published by Elsevier Publishing Company. This book was released on 1991 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pharmacological fight against epilepsy began many centuries ago when Hippocrates discovered that the cause of epilepsy is natural, as opposed to supernatural and, as a consequence, must be treated with a natural remedy. Even though science has significantly progressed since that era, the challenge to find remedies for epilepsy is ever present. The aim of this particular volume is to offer an up-to-date review of the most recent advances in antiepileptic drug development, considered from various viewpoints: (i) general, by taking into account the size of refractory epilepsy and its related problems; (ii) experimental, by exploring the mechanisms of epileptogenesis and the possiblility of influencing it through drugs, and (iii) clinical, by describing the results obtained with compounds currently at an advanced stage of testing.

Epilepsy Across the Spectrum

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Publisher : National Academies Press
ISBN 13 : 0309259533
Total Pages : 568 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Epilepsy Across the Spectrum by : Institute of Medicine

Download or read book Epilepsy Across the Spectrum written by Institute of Medicine and published by National Academies Press. This book was released on 2012-07-29 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although epilepsy is one of the nation's most common neurological disorders, public understanding of it is limited. Many people do not know the causes of epilepsy or what they should do if they see someone having a seizure. Epilepsy is a complex spectrum of disorders that affects an estimated 2.2 million Americans in a variety of ways, and is characterized by unpredictable seizures that differ in type, cause, and severity. Yet living with epilepsy is about much more than just seizures; the disorder is often defined in practical terms, such as challenges in school, uncertainties about social situations and employment, limitations on driving, and questions about independent living. The Institute of Medicine was asked to examine the public health dimensions of the epilepsies, focusing on public health surveillance and data collection; population and public health research; health policy, health care, and human services; and education for people with the disorder and their families, health care providers, and the public. In Epilepsy Across the Spectrum, the IOM makes recommendations ranging from the expansion of collaborative epilepsy surveillance efforts, to the coordination of public awareness efforts, to the engagement of people with epilepsy and their families in education, dissemination, and advocacy for improved care and services. Taking action across multiple dimensions will improve the lives of people with epilepsy and their families. The realistic, feasible, and action-oriented recommendations in this report can help enable short- and long-term improvements for people with epilepsy. For all epilepsy organizations and advocates, local, state, and federal agencies, researchers, health care professionals, people with epilepsy, as well as the public, Epilepsy Across the Spectrum is an essential resource.

Polypharmacology in Drug Discovery

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Publisher : John Wiley & Sons
ISBN 13 : 0470590904
Total Pages : 542 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Polypharmacology in Drug Discovery by : Jens-Uwe Peters

Download or read book Polypharmacology in Drug Discovery written by Jens-Uwe Peters and published by John Wiley & Sons. This book was released on 2012-03-13 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential outline of the main facets of polypharmacology in drug discovery research Extending drug discovery opportunities beyond the "one drug, one target" philosophy, a polypharmacological approach to the treatment of complex diseases is emerging as a hot topic in both industry and academic research. Polypharmacology in Drug Discovery presents an overview of the various facets of polypharmacology and how it can be applied as an innovative concept for developing medicines for treating bacterial infections, epilepsy, cancer, psychiatric disorders, and more. Filled with a collection of instructive case studies that reinforce the material and illuminate the subject, this practical guide: Covers the two-sided nature of polypharmacology—its contribution to adverse drug reactions and its benefit in certain therapeutic drug classes Addresses the important topic of polypharmacology in drug discovery, a subject that has not been thoroughly covered outside of scattered journal articles Overviews state-of-the-art approaches and developments to help readers understand concepts and issues related to polypharmacology Fosters interdisciplinary drug discovery research by embracing computational, synthetic, in vitro and in vivo pharmacological and clinical aspects of polypharmacology A clear road map for helping readers successfully navigate around the problems involved with promiscuous ligands and targets, Polypharmacology in Drug Discovery provides real examples, in-depth explanations and discussions, and detailed reviews and opinions to spark inspiration for new drug discovery projects.

Basic and Clinical Pharmacology

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Publisher :
ISBN 13 : 9780071179683
Total Pages : 1217 pages
Book Rating : 4.1/5 (796 download)

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Book Synopsis Basic and Clinical Pharmacology by : Bertram G. Katzung

Download or read book Basic and Clinical Pharmacology written by Bertram G. Katzung and published by . This book was released on 2001 with total page 1217 pages. Available in PDF, EPUB and Kindle. Book excerpt: This best selling book delivers the most current, complete, and authoritative pharmacology information to students and practitioners. All sections are updated with new drug information and references. New! Many new figures and diagrams, along with boxes of highlighted material explaining the "how and why" behind the facts.

The Carbonic Anhydrases

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Publisher : Birkhäuser
ISBN 13 : 303488446X
Total Pages : 614 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis The Carbonic Anhydrases by : W.R. Chegwidden

Download or read book The Carbonic Anhydrases written by W.R. Chegwidden and published by Birkhäuser. This book was released on 2013-11-11 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbonic anhydrase (CA) is a seemingly ubiquitous enzyme of profound physiological importance, which plays essential roles in respiration, acid-base homeostasis, bone resorption, calcification, photosynthesis, several biosynthetic pathways and a variety of processes involving ion, gas and fluid transfer. This enzyme, which is present in at least three gene families (a, ß, ?), has found favour as a model for the study of evolution of gene families and for site-directed mutagenesis in structure/function relationships, for protein folding and for transgenic and gene target studies. Since the early use of CA inhibitors as diuretics and in treating congestive heart failure, the enzyme has been target of considerable clinical attention. Much of this is now focused on endeavours to produce a new generation of such drugs for the effective treatment of glaucoma and other potential applications. Recent data, suggesting links between CA and various disease processes, including cancer, have stimulated further...

Iminosugars

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Publisher : John Wiley & Sons
ISBN 13 : 9780470517444
Total Pages : 482 pages
Book Rating : 4.5/5 (174 download)

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Book Synopsis Iminosugars by : Philippe Compain

Download or read book Iminosugars written by Philippe Compain and published by John Wiley & Sons. This book was released on 2007-10-22 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Iminosugars form undoubtedly the most attractive of carbohydrate mimics reported so far. In these structures, the substitution of the endocyclic oxygen of sugars by a basic nitrogen atom leads to remarkable biological properties and raises many challenges in organic synthesis. Since the discovery of their biological activity as glycosidase inhibitors in the 1970’s, these polyvalent molecules have progressively made their way from the laboratory to the clinic. The impressive series of discoveries in the field over the past ten years indicates clearly that it is “a boom time” for iminosugar chemistry and biology. The scope of their profile as inhibitors has been extended to a number of enzymes such as phosphorylases, glycosyltransferases or metalloproteinases, and iminosugars now constitute lead compounds for the development of new therapeutic agents for a wide range of diseases including diabetes, viral infections, lysosomal storage disorders and tumor metastasis. Latest developments, from iminosugar synthesis to their use in clinical studies, are presented in this book, which contains contributions from over fifteen of the major chemists, biochemists and drug developers in this rapidly expanding field. An extensive table correlating the structures of more than 600 iminosugars of therapeutic interest with their biological activities is also included in the book and should prove particularly useful to aid with the design and the discovery of novel bioactive substances. Iminosugars: From Synthesis to Therapeutic Application provides a unique resource for academic and industrial researchers working in the field of iminosugars and glycomimetics of biological and/or therapeutic interest: organic chemists, medicinal chemists, carbohydrate chemists and medical scientists.

Frequently Prescribed Medications

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Publisher : Jones & Bartlett Learning
ISBN 13 : 0763781177
Total Pages : 272 pages
Book Rating : 4.7/5 (637 download)

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Book Synopsis Frequently Prescribed Medications by : Michael Mancano

Download or read book Frequently Prescribed Medications written by Michael Mancano and published by Jones & Bartlett Learning. This book was released on 2010-11-12 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Health Sciences & Professions