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Calcul Efficace De La Structure Des Proteines A Partir De Contacts Evolutifs
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Book Synopsis Calcul efficace de la structure des protéines à partir de contacts évolutifs by : Fabrice Allain
Download or read book Calcul efficace de la structure des protéines à partir de contacts évolutifs written by Fabrice Allain and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Les méthodes de prédiction structurale constituent une alternative relativement efficace aux approches expérimentales pour donner un premier aperçu du repliement natif d'une protéine. L'écart entre le nombre de structures et de séquences protéiques disponibles dans les bases de données ne cesse en effet de croître depuis l'arrivée des technologies de séquençage à haut débit. Cette forte croissance des informations génomiques a remis à l'ordre du jour des techniques modélisant les données capturées au cours de l'évolution. La conservation d'une fonction protéique impose de fortes contraintes sur les contacts impliqués dans le repliement et la fonction se traduisant par une trajectoire évolutive commune. Une fois détectées, ces interactions peuvent aider à modéliser la conformation d'une protéine. Les méthodes résolvant la structure tridimensionnelle des protéines à partir des données évolutives présentent encore plusieurs limitations notamment pour la détection des contacts faux positifs. Ces problèmes restent similaires à ceux rencontrés en détermination de structure par spectrométrie de Résonnance Magnétique Nucléaire où l'intégration des données est un processus clairement établit et en grande partie automatisé. Le logiciel ARIA (Ambiguous Restraints for Iterative Assignment) utilise le concept de contraintes de distances ambiguës et suit un processus itératif afin d'attribuer et d'affiner la liste des noyaux proches dans l'espace pour calculer un ensemble de modèles structuraux en accord avec les données. Ce travail a pour objectif d'adapter cette approche pour prédire de novo la structure d'une protéine en utilisant l'information évolutive.
Book Synopsis The Tree of Life by : Guillaume Lecointre
Download or read book The Tree of Life written by Guillaume Lecointre and published by Harvard University Press. This book was released on 2006 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Did you know that you are more closely related to a mushroom than to a daisy? That dinosaurs are still among us? That the terms "fish" and "invertebrates" do not indicate scientific groupings? All this is the result of major changes in classification. This book diagrams the tree of life according to the most recent methods of this system.
Download or read book Terra 2008 written by Leslie Rainer and published by Getty Publications. This book was released on 2011-06-14 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Earthen architecture constitutes one of the most diverse forms of cultural heritage and one of the most challenging to preserve. It dates from all periods and is found on all continents but is particularly prevalent in Africa, where it has been a building tradition for centuries. Sites range from ancestral cities in Mali to the palaces of Abomey in Benin, from monuments and mosques in Iran and Buddhist temples on the Silk Road to Spanish missions in California. This volume's sixty-four papers address such themes as earthen architecture in Mali, the conservation of living sites, local knowledge systems and intangible aspects, seismic and other natural forces, the conservation and management of archaeological sites, research advances, and training.
Author :Food and Agriculture Organization of the United Nations Publisher :Food & Agriculture Org. ISBN 13 :9789251045411 Total Pages :20 pages Book Rating :4.0/5 (454 download)
Book Synopsis What is the Code of Conduct for Responsible Fisheries? by : Food and Agriculture Organization of the United Nations
Download or read book What is the Code of Conduct for Responsible Fisheries? written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2001 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: The actual Code of conduct is also available (1996) (ISBN 9251038341).
Book Synopsis Numerical Methods for Partial Differential Equations by : Sandip Mazumder
Download or read book Numerical Methods for Partial Differential Equations written by Sandip Mazumder and published by Academic Press. This book was released on 2015-12-01 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Numerical Methods for Partial Differential Equations: Finite Difference and Finite Volume Methods focuses on two popular deterministic methods for solving partial differential equations (PDEs), namely finite difference and finite volume methods. The solution of PDEs can be very challenging, depending on the type of equation, the number of independent variables, the boundary, and initial conditions, and other factors. These two methods have been traditionally used to solve problems involving fluid flow. For practical reasons, the finite element method, used more often for solving problems in solid mechanics, and covered extensively in various other texts, has been excluded. The book is intended for beginning graduate students and early career professionals, although advanced undergraduate students may find it equally useful. The material is meant to serve as a prerequisite for students who might go on to take additional courses in computational mechanics, computational fluid dynamics, or computational electromagnetics. The notations, language, and technical jargon used in the book can be easily understood by scientists and engineers who may not have had graduate-level applied mathematics or computer science courses. Presents one of the few available resources that comprehensively describes and demonstrates the finite volume method for unstructured mesh used frequently by practicing code developers in industry Includes step-by-step algorithms and code snippets in each chapter that enables the reader to make the transition from equations on the page to working codes Includes 51 worked out examples that comprehensively demonstrate important mathematical steps, algorithms, and coding practices required to numerically solve PDEs, as well as how to interpret the results from both physical and mathematic perspectives
Book Synopsis Faecal Sludge Management by : Linda Strande
Download or read book Faecal Sludge Management written by Linda Strande and published by IWA Publishing. This book was released on 2014-08-15 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is estimated that literally billions of residents in urban and peri-urban areas of Africa, Asia, and Latin America are served by onsite sanitation systems (e.g. various types of latrines and septic tanks). Until recently, the management of faecal sludge from these onsite systems has been grossly neglected, partially as a result of them being considered temporary solutions until sewer-based systems could be implemented. However, the perception of onsite or decentralized sanitation technologies for urban areas is gradually changing, and is increasingly being considered as long-term, sustainable options in urban areas, especially in low- and middle-income countries that lack sewer infrastructures. This is the first book dedicated to faecal sludge management. It compiles the current state of knowledge of the rapidly evolving field of faecal sludge management, and presents an integrated approach that includes technology, management, and planning based on Sandecs 20 years of experience in the field. Faecal Sludge Management: Systems Approach for Implementation and Operation addresses the organization of the entire faecal sludge management service chain, from the collection and transport of sludge, and the current state of knowledge of treatment options, to the final end use or disposal of treated sludge. The book also presents important factors to consider when evaluating and upscaling new treatment technology options. The book is designed for undergraduate and graduate students, and engineers and practitioners in the field who have some basic knowledge of environmental and/or wastewater engineering.
Book Synopsis Mammals of Algeria by : Kazimierz Kowalski
Download or read book Mammals of Algeria written by Kazimierz Kowalski and published by . This book was released on 1991 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :Food and Agriculture Organization of the United Nations Publisher :Food & Agriculture Org. ISBN 13 :9789251039717 Total Pages :52 pages Book Rating :4.0/5 (397 download)
Book Synopsis Aquaculture Development by : Food and Agriculture Organization of the United Nations
Download or read book Aquaculture Development written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 1997 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides annotations to the Principles of Article 9 of the Code of Conduct for Responsible Fisheries. These annotations are meant to serve as general guidance, and should be taken as suggestions or observations intended to assist those interested in identifying their own criteria and options for actions, as well as partners for collaboration, in support of sustainable aquaculture development.
Book Synopsis Symbolic Economies by : Jean-Joseph Goux
Download or read book Symbolic Economies written by Jean-Joseph Goux and published by Cornell University Press. This book was released on 1990 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: A major participant in the influential Tel Quel group in France, Jean-Joseph Goux here offers a bold reevaluation of both the Marxist economic model and the Freudian concept of the unconscious. Symbolic Economies makes available for the first time in English generous selections from Goux's Freud, Marx: Economie et symbolique (1973) and Les iconoclastes (1978). Goux brings the theories of historical materialism and of psychoanalysis into play to illuminate and enrich each other, and undertakes a compelling integration of the contributions of structuralism and post-structuralism. Looking closely at the work of such major figures as Lacan, Derrida, and Nietzsche, Goux extends the implications of Marxism and Freudianism to an interdisciplinary semiotics of value and proposes a radical concept of exchange. Literary theorists, philosophers, social scientists, cultural historians, and feminist critics alike will welcome this important and provocative work.
Book Synopsis Ecritures digitales by : Claire Clivaz
Download or read book Ecritures digitales written by Claire Clivaz and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecritures digitales aims to demonstrate how digital writing, as new technology, contributes to the emergence of a reconfigured relationship between the human body and the machines, and how this transition influences the Jewish-Christian textual corpus referred to as "the Scriptures". Ecritures digitales souhaite démontrer de quelle manière l'écriture digitale, en tant que nouvelle technologie, contribue à l'émergence d'une relation innovante entre le corps humain et les machines, et influence le corpus textuel judéo-chrétien désigné comme «les Ecritures».
Book Synopsis Lipid Oxidation by : Edwin N. Frankel
Download or read book Lipid Oxidation written by Edwin N. Frankel and published by Elsevier. This book was released on 2014-01-23 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this second edition, Edwin Frankel has updated and extended his now well-known book Lipid oxidation which has come to be regarded as the standard work on the subject since the publication of the first edition seven years previously. His main objective is to develop the background necessary for a better understanding of what factors should be considered, and what methods and lipid systems should be employed, to achieve suitable evaluation and control of lipid oxidation in complex foods and biological systems. The oxidation of unsaturated fatty acids is one of the most fundamental reactions in lipid chemistry. When unsaturated lipids are exposed to air, the complex, volatile oxidation compounds that are formed cause rancidity. This decreases the quality of foods that contain natural lipid components as well as foods in which oils are used as ingredients. Furthermore, products of lipid oxidation have been implicated in many vital biological reactions, and evidence has accumulated to show that free radicals and reactive oxygen species participate in tissue injuries and in degenerative disease. Although there have been many significant advances in this challenging field, many important problems remain unsolved. This second edition of Lipid oxidation follows the example of the first edition in offering a summary of the many unsolved problems that need further research. The need to understand lipid oxidation is greater than ever with the increased interest in long-chain polyunsaturated fatty acids, the reformulation of oils to avoid hydrogenation and trans fatty acids, and the enormous attention given to natural phenolic antioxidants, including flavonoids and other phytochemicals.
Book Synopsis Mammalian Synthetic Biology by : Jamie Davies
Download or read book Mammalian Synthetic Biology written by Jamie Davies and published by . This book was released on 2019-12-12 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written primarily for mid-to-upper level undergraduates, this primer will introduce students to topics at the forefront of the subject that are being applied to probe biological problems, or to address the most pressing issues facing society. These topics will include those that form thecornerstone of contemporary research, helping students to make the transition to active researcher.This primer introduces the challenges and opportunities of applying synthetic biological techniques to mammalian cells, tissues, and organisms. It covers the special features that make engineering mammalian systems different from engineering bacteria, fungi, and plants, and provides an overview ofcurrent techniques. A variety of cutting-edge examples illustrate the different purposes of mammalian synthetic biology, including pure biomedical research, drug production, tissue engineering, and regenerative medicine.
Book Synopsis Advances in Archaeological Method and Theory by : Michael B Schiffer
Download or read book Advances in Archaeological Method and Theory written by Michael B Schiffer and published by Academic Press. This book was released on 2014-06-30 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Archaeological Method and Theory, Volume 8 is a collection of papers that discusses postprocessual archaeology, bone technology, and tree-ring dating in Eastern North America. One paper discriminates between the process and norm, and eliminates the dichotomy by locating human agency and the active. It focuses on monitoring individuals as being in the center of social theory. Another paper discuses the physical model and the textual model that describe the basic components of an archaeological record. For example, the first model implies that archaeological inferences move from material components of the record to material phenomena in the past. The second model assumes that archaeological inference should move from material phenomena to mental phenomena, from material symbols to the ideas and beliefs they encode. Another paper explains the use of analogy as a useful tool in archaeological considerations. One paper investigates bones as a material for study, including the analysis of carnivore-induced fractures or hominid-induced modifications from using bones as tools. The collection is suitable for sociologists, anthropologist, professional or amateur archaeologists, and museum curators studying archaeological artifacts.
Book Synopsis Percutaneous Needle Biopsy by : Jesus Zornoza
Download or read book Percutaneous Needle Biopsy written by Jesus Zornoza and published by . This book was released on 1981 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Tropical Marine Plants of Palau by : Hideo Ohba
Download or read book Tropical Marine Plants of Palau written by Hideo Ohba and published by . This book was released on 2007 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biomimicry written by Janine M. Benyus and published by Harper Collins. This book was released on 2009-08-11 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Repackaged with a new afterword, this "valuable and entertaining" (New York Times Book Review) book explores how scientists are adapting nature's best ideas to solve tough 21st century problems. Biomimicry is rapidly transforming life on earth. Biomimics study nature's most successful ideas over the past 3.5 million years, and adapt them for human use. The results are revolutionizing how materials are invented and how we compute, heal ourselves, repair the environment, and feed the world. Janine Benyus takes readers into the lab and in the field with maverick thinkers as they: discover miracle drugs by watching what chimps eat when they're sick; learn how to create by watching spiders weave fibers; harness energy by examining how a leaf converts sunlight into fuel in trillionths of a second; and many more examples. Composed of stories of vision and invention, personalities and pipe dreams, Biomimicry is must reading for anyone interested in the shape of our future.
Book Synopsis Antioxidants in Food and Biology by : Edwin Nessim Frankel
Download or read book Antioxidants in Food and Biology written by Edwin Nessim Frankel and published by . This book was released on 2007 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed to help all those who need to prevent or control oxidation, especially in food products, or to understand the properties of antioxidants in food, nutrition, health and medicine, this title covers chapters such as the chemistry of antioxidation, antioxidant action in multi-phase systems, antioxidants in biology, and among other topics. The field of antioxidants has expanded over the last six decades into a wide variety of multi-disciplinary areas that impact foods and health. Antioxidants in food and biology: Facts and fiction is a handbook designed to help all those who need to prevent or control oxidation, especially in food products, or to understand the properties of antioxidants in food, nutrition, health and medicine. It conveys the complexity of antioxidant chemistry by providing an appreciation of the various phenomena that affect oxidation and its inhibition in foods and biological systems. Beginning with the underlying chemistry, the book moves on to explain how the activity of antioxidants is affected at the interface of complex multiphase lipid systems and to discuss the problems of evaluating the activities of antioxidants in foods and biological systems. After reviewing the antioxidants present in various foods, the author addresses the hypothesis that the health of an individual is influenced by the efficiency of various protection systems against oxidant damage. He also considers whether or not additional or more effective natural antioxidants are needed in our diet to reduce oxidative stress from dietary and environmental factors, and to thus reduce the risk of cardiovascular disease.
