Calcium Study to Alzheimer's Therapeutics

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Publisher : Cambridge Scholars Publishing
ISBN 13 : 1036404242
Total Pages : 491 pages
Book Rating : 4.0/5 (364 download)

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Book Synopsis Calcium Study to Alzheimer's Therapeutics by : Seung Hyun Yoo

Download or read book Calcium Study to Alzheimer's Therapeutics written by Seung Hyun Yoo and published by Cambridge Scholars Publishing. This book was released on 2024-04-26 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will be informative and challenging for scientists, enlightening and stimulating for intellectuals and serious students, and highly beneficial and interesting for Alzheimer’s workers and the public. The first half is a historical account of recent scientific discoveries on calcium (Ca2+) storage and control organelles in cells, explaining the major role of secretory granules in the cytoplasm and the newly identified nucleoplasmic Ca2+ store vesicles in the nucleus. The second half not only presents unprecedented and highly relevant information on the pathogenic process of Alzheimer’s disease and current research, but also introduces Alzheimer’s therapeutics, which is ready to proceed to clinical trials. In light of this, it contains valuable information which will greatly benefit Alzheimer’s workers, patients, the families, and anybody interested in Alzheimer’s disease.

Calcium Signalling in Alzheimer’s Disease

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Author :
Publisher : MDPI
ISBN 13 : 3036504982
Total Pages : 162 pages
Book Rating : 4.0/5 (365 download)

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Book Synopsis Calcium Signalling in Alzheimer’s Disease by : Mounia Chami

Download or read book Calcium Signalling in Alzheimer’s Disease written by Mounia Chami and published by MDPI. This book was released on 2021-04-22 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer’s disease (AD) is the most well-known neurodegenerative disorder, causing dementia. In recent decades, several studies have reported calcium dysregulation in AD occurring through the intervention of several calcium receptors and channels, and affecting different cellular compartments, such as mitochondria, the endoplasmic reticulum, lysosomes, and microdomains within the plasma membrane. Calcium signalling dysregulation is now considered a common proximal cause of dysfunctional neurons and glial supporting cells. This book gathers the newest results and advances in calcium signaling deregulation mechanisms in AD, how they are linked to other players involved in AD, and the potential therapies targeting calcium alterations to treat AD.

Magnesium in the Central Nervous System

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Publisher : University of Adelaide Press
ISBN 13 : 0987073052
Total Pages : 354 pages
Book Rating : 4.9/5 (87 download)

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Book Synopsis Magnesium in the Central Nervous System by : Robert Vink

Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Capacitative Calcium Entry

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Author :
Publisher : Springer
ISBN 13 :
Total Pages : 238 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Capacitative Calcium Entry by : James W. Putney

Download or read book Capacitative Calcium Entry written by James W. Putney and published by Springer. This book was released on 1997-06-15 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Apolipoprotein E and Alzheimer’s Disease

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Publisher : Springer Science & Business Media
ISBN 13 : 3642801099
Total Pages : 208 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Apolipoprotein E and Alzheimer’s Disease by : A.D. Roses

Download or read book Apolipoprotein E and Alzheimer’s Disease written by A.D. Roses and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is now considerable genetic evidence that the type 4 allele of the apolipoprotein E gene is a major susceptibility factor associated with late-onset Alzheimer's disease, the common form of the disease defined as starting after sixty years of age. The role of apolipoprotein E in normal brain metabolism and in the pathogenesis of Alzheimer's disease are new and exciting avenues of research. This book, written by the most outstanding scientists in this new filed, is the first presentation of results concerning the implications of apolipoprotein E on the genetics, cell biology, neuropathology, biochemistry, and therapeutic management of Alzheimer's disease.

Alzheimer's Disease Drug Development

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Publisher : Cambridge University Press
ISBN 13 : 1108838669
Total Pages : 575 pages
Book Rating : 4.1/5 (88 download)

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Book Synopsis Alzheimer's Disease Drug Development by : Jeffrey Cummings

Download or read book Alzheimer's Disease Drug Development written by Jeffrey Cummings and published by Cambridge University Press. This book was released on 2022-03-31 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.

Advances in Dementia Research and Treatment: 2013 Edition

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Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481682385
Total Pages : 164 pages
Book Rating : 4.4/5 (816 download)

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Book Synopsis Advances in Dementia Research and Treatment: 2013 Edition by :

Download or read book Advances in Dementia Research and Treatment: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Dementia Research and Treatment: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about ZZZAdditional Research in a concise format. The editors have built Advances in Dementia Research and Treatment: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Dementia Research and Treatment: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Trial Designs and Outcomes in Dementia Therapeutic Research

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Author :
Publisher : CRC Press
ISBN 13 : 0203340655
Total Pages : 324 pages
Book Rating : 4.2/5 (33 download)

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Book Synopsis Trial Designs and Outcomes in Dementia Therapeutic Research by : Kenneth Rockwood

Download or read book Trial Designs and Outcomes in Dementia Therapeutic Research written by Kenneth Rockwood and published by CRC Press. This book was released on 2005-11-23 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Given the increased attention of clinicians, researchers, and the pharmaceutical industry to the management and treatment of dementia not only in the elderly but also in increasingly younger populations, the demands for effective evidence-based pharmaceutical control of dementia and quantitative assessment of outcomes have increased. From the first steps in the early 1960s to the controversial landmark paper of Summers and colleagues to the most recent trials, it is clear both that much progress has been made and that much remains to be done. This book is written to take stock of what is now usefully known and to speculate on directions for the future.

Ion Channels—Advances in Research and Application: 2012 Edition

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Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464993408
Total Pages : 459 pages
Book Rating : 4.4/5 (649 download)

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Download or read book Ion Channels—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ion Channels—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Ion Channels. The editors have built Ion Channels—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Ion Channels in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Ion Channels—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Delirium, Dementia, Amnestic, Cognitive Disorders: Advances in Research and Treatment: 2011 Edition

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Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464923922
Total Pages : 348 pages
Book Rating : 4.4/5 (649 download)

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Download or read book Delirium, Dementia, Amnestic, Cognitive Disorders: Advances in Research and Treatment: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Delirium, Dementia, Amnestic, Cognitive Disorders: Advances in Research and Treatment: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Delirium, Dementia, Amnestic, Cognitive Disorders in a concise format. The editors have built Delirium, Dementia, Amnestic, Cognitive Disorders: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Delirium, Dementia, Amnestic, Cognitive Disorders in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Delirium, Dementia, Amnestic, Cognitive Disorders: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Pharmacological Mechanisms in Alzheimer's Therapeutics

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0387715223
Total Pages : 337 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Pharmacological Mechanisms in Alzheimer's Therapeutics by : A. Claudio Cuello

Download or read book Pharmacological Mechanisms in Alzheimer's Therapeutics written by A. Claudio Cuello and published by Springer Science & Business Media. This book was released on 2007-12-22 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: The need for effective therapy to treat Alzheimer’s disease is greater than ever, but there is still no drug therapy that can stop or reverse the progression of the disease. There is, however, a great deal of anticipation over the imminent development of effective therapies as a result of the identification of promising targets for drug development. This book investigates these targets and examines ongoing strategies to develop effective therapies for this devastating neurodegenerative condition.

Mental Disorders: Advances in Research and Treatment: 2011 Edition

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Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464924953
Total Pages : 196 pages
Book Rating : 4.4/5 (649 download)

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Download or read book Mental Disorders: Advances in Research and Treatment: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mental Disorders: Advances in Research and Treatment: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Mental Disorders. The editors have built Mental Disorders: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Mental Disorders in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Mental Disorders: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Basic, Clinical, and Therapeutic Aspects of Alzheimer’s and Parkinson’s Diseases

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Publisher : Springer Science & Business Media
ISBN 13 : 1468458442
Total Pages : 797 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Basic, Clinical, and Therapeutic Aspects of Alzheimer’s and Parkinson’s Diseases by : Toshiharu Nagatsu

Download or read book Basic, Clinical, and Therapeutic Aspects of Alzheimer’s and Parkinson’s Diseases written by Toshiharu Nagatsu and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 797 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume work contains the full text of the oral and poster presentations and the general discussion at the round table discussion of the Second International Conference on Alzheimer's and Parkinson's Diseases: Basic and Therapeutic Strategies, held at the Kyoto Park Hotel in Kyoto, Japan, on November 6-10, 1989. The First Conference was held at the Aviya Sonesta Hotel in Eilat, Israel, on March 24-27, 1985. The record of this First Conference was published by Plenum Press in 1986 as Volume 29 in Advances in Behavioral Biology, under the title "Alzheimer's and Parkinson's Diseases: Strategies for Research and Development." We are happy that the comprehensive texts of the oral and poster presentations of the Second Conference could again be published within the framework of this series. Since the First Conference in 1985, rapid progress has been made in both basic and 'therapeutic aspects of these diseases. About 700 scientists from allover the world participated in the Second Conference, and 300 papers were presented in oral and poster sessions. Many people and organizations have helped to organize this multi disciplinary international conference and hence have contributed to the scientific quality of these two volumes. We thank the members of the organizing committee, the organizations that provided financial support, and the contributing scientists for their enthusiastic participation. These two volumes follow the same publishing philosophy as the volume derived from the First Conference. They span a broad spectrum of topics and bridge preclinical and clinical concepts related to these diseases.

Alzheimer's Disease

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Publisher : John Wiley & Sons
ISBN 13 : 0470851740
Total Pages : 888 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis Alzheimer's Disease by : Khalid Iqbal

Download or read book Alzheimer's Disease written by Khalid Iqbal and published by John Wiley & Sons. This book was released on 2003-01-24 with total page 888 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's Disease is an ever present problem affecting millions of people around the world and, as people's average lifespan lengthens, its prevalence is set to increase. A global effort is needed to combat the disease, including research to investigate the causes, development of effective treatments and, ultimately, prevention of the disease. Published every two years, these timely books discuss the very latest research. This new volume provides a unique source of reference to the important work being done in this field, it gives academics and clinicians an opportunity to learn about cutting edge developments and covers all aspects of Alzheimer's Disease, including diagnosis, clinical course, epidemiological course and therapeutics and disease mechanisms. Alzheimer's Disease: Advances in Etiology, Pathogenesis and Therapeutics will provide essential information for basic and clinical researchers in Alzheimer's Disease and other dementias as well as for those who care for patients.

Advances in Dementia Research and Treatment: 2012 Edition

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Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464991731
Total Pages : 742 pages
Book Rating : 4.4/5 (649 download)

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Download or read book Advances in Dementia Research and Treatment: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Dementia Research and Treatment / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Dementia. The editors have built Advances in Dementia Research and Treatment / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Dementia in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Dementia Research and Treatment / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Current State of Alzheimer's Disease Research and Therapeutics

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Author :
Publisher : Academic Press
ISBN 13 : 0123948452
Total Pages : 399 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Current State of Alzheimer's Disease Research and Therapeutics by :

Download or read book Current State of Alzheimer's Disease Research and Therapeutics written by and published by Academic Press. This book was released on 2012-07-24 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Advances in Pharmacology explores the Current State of Alzheimer's Disease Research and Therapeutics. Chapters cover such topics as the The role heat shock proteins play in the Alzheimer's Theater, Gamma-Secretase as a Target for Alzheimer's Disease, and Identification of protein kinase C for the treatment of dementias. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike. Explores the current state of Alzheimer's disease research and therapeutics Chapters cover a variety of topics such as the role heat shock proteins play in the Alzheimer's theater, gamma-secretase as a target for Alzheimer's disease, and identification of protein kinase C for the treatment of dementias With the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike

Biomedical Index to PHS-supported Research: pt. A. Subject access A-H

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Author :
Publisher :
ISBN 13 :
Total Pages : 1064 pages
Book Rating : 4.:/5 (319 download)

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Download or read book Biomedical Index to PHS-supported Research: pt. A. Subject access A-H written by and published by . This book was released on 1992 with total page 1064 pages. Available in PDF, EPUB and Kindle. Book excerpt: