Calcium-Antagonismus

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Publisher : Springer-Verlag
ISBN 13 : 3642675956
Total Pages : 372 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Calcium-Antagonismus by : A. Fleckenstein

Download or read book Calcium-Antagonismus written by A. Fleckenstein and published by Springer-Verlag. This book was released on 2013-03-07 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Internationales Symposium, 8.-9. Dezember 1978, Frankfurt/ Main

Calcium-antagonismus

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Publisher :
ISBN 13 : 9783891430019
Total Pages : 274 pages
Book Rating : 4.4/5 (3 download)

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Book Synopsis Calcium-antagonismus by : Ulrich Althaus

Download or read book Calcium-antagonismus written by Ulrich Althaus and published by . This book was released on 1984 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Evaluation of Beat Blocker and Calcium Antagonist Drugs

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9400975619
Total Pages : 409 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis The Evaluation of Beat Blocker and Calcium Antagonist Drugs by : J. Morganroth

Download or read book The Evaluation of Beat Blocker and Calcium Antagonist Drugs written by J. Morganroth and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the beginning of the 1980's it was becoming increasingly evident that the lack of approval of new cardiovascular agents for use by clinicians in the United States for the treatment of cardiovascular disorders was becoming a problem. Patients requiring medical therapy for hypertension, angina pectoris, arrhythmias, congestive heart failure, and vasospastic disorders of the coronary arteries could receive in the United States only a small number of the drugs available to physicians in the rest of the world. In fact, as the 1980's began, there was only one available beta blocking agent released by The Food and Drug Administration; and even as of this writing, no oral calcium antagonist agent. This lag, in part, has been due to the confusion of proper and expeditious methods to define safety and efficacy of such agents so that the United States regulatory agency (Food and Drug Administration) could approve the use of such agents by clinicians. The vast number of new beta blocker and calcium antagonist agents being developed, as well as the long-term use abroad of many new drugs, has raised important questions as to how relative safety and efficacy of such agents can be determined to facilitate availability in the United States.

Calcium-Antagonismus

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Author :
Publisher :
ISBN 13 :
Total Pages : 290 pages
Book Rating : 4.:/5 (311 download)

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Book Synopsis Calcium-Antagonismus by : Ulrich Althaus

Download or read book Calcium-Antagonismus written by Ulrich Althaus and published by . This book was released on 1984 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Calcium Antagonists

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642748872
Total Pages : 414 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Calcium Antagonists by : Helmut Lydtin

Download or read book Calcium Antagonists written by Helmut Lydtin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume critically and objectively analyses the literature up to 1989 and presents a guide to the practical use of all calcium antagonists which have been thoroughly investigated to date. It begins with a concise review of physiological principles as a basis for a discussion of the general and specific pharmacodynamics and pharmacokinetics of calcium antagonists. Special emphasis is given to their therapeutic use in practice, precise dosage schedules are provided, interactions with other medications described, and therapeutic alternatives considered.

Recent Aspects in Calcium Antagonism

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Publisher :
ISBN 13 :
Total Pages : 232 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Recent Aspects in Calcium Antagonism by : Paul R. Lichtlen

Download or read book Recent Aspects in Calcium Antagonism written by Paul R. Lichtlen and published by . This book was released on 1985 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Hypertrophic Cardiomyopathy

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Publisher : Springer Science & Business Media
ISBN 13 : 3642682820
Total Pages : 344 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Hypertrophic Cardiomyopathy by : M. Kaltenbach

Download or read book Hypertrophic Cardiomyopathy written by M. Kaltenbach and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: First described in 1907 by Schicke but recognized as a clinical entity only as recently as 1958, when Teare published the pathologic findings in patients with hypertrophic cardiomyopathy (HeM), an explosion of knowledge about this fascinating disease has occurred, which has caused a profound evolution of our understanding of its broad pathophysiologic and clinical spectrum. Progress has been particularly rapid in the past few years when M-mode echocardiography, and more recently 2-dimen sional echocardiography have been applied to the study ofHCM. In addition to new insights as to what the disease is, there has been enormous progress concerning its treatment, with the application of beta-adrenergic blocking agents and surgical relief of left ventricular outflow tract obstruction. Although these approaches have led to great strides in the symptomatic control of the disease, many patients' symptoms have remained refactory to medical and surgical therapy. Most discouragingly, sudden death still occurs, even in patients on large doses of beta-blocking agents and in patients who have had surgical relief of left ventricular outflow tract obstruction.

Cardiovascular Effects of Dihydropyridine-Type Calcium Antagonists and Agonists

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Publisher : Springer Science & Business Media
ISBN 13 : 3642704999
Total Pages : 520 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Cardiovascular Effects of Dihydropyridine-Type Calcium Antagonists and Agonists by : A. Fleckenstein

Download or read book Cardiovascular Effects of Dihydropyridine-Type Calcium Antagonists and Agonists written by A. Fleckenstein and published by Springer Science & Business Media. This book was released on 2013-03-12 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Held at Boppard, Germany, October 3-6, 1984

Calcium in Biological Systems

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Publisher : Springer Science & Business Media
ISBN 13 : 1461323770
Total Pages : 697 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Calcium in Biological Systems by : Ronald P. Rubin

Download or read book Calcium in Biological Systems written by Ronald P. Rubin and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 697 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is based in part upon the proceedings of the Calcium Theme held during the 67th Annual Meeting of the Federation of American Societies for Experimental Biology, which took place in Chicago, AprillO-lS, 1983. The American Society for Pharmacology and Experimental Therapeutics had the primary responsibility for organizing the scientific program with the assistance of other member societies, including the American Physiology Society, American Association of Pathologists, and American Institute of Nutrition. The purpose of the Calcium Theme was to review progress in the diverse areas of investigation bearing on the ubiquitous role of calcium in biological systems. In addition to contributions from those participating in the Theme, this volume also includes a number of invited papers that were added to fill certain voids in topics covered. The authors were selected because they are investigators active in the mainstream of their particular research area, possessing the acumen to analyze cogently not only their own recent findings but also to relate these findings to their respective area. New information as well as reviews of current concepts generally highlight the individual contributions. Undoubtedly, some readers may argue with the emphasis made and/or the conclusions reached on individual topics. In such cases, other volumes will hopefully provide a forum for alternative points of view. Due to the broad scope of subjects covered and the large number of contributions, the papers have been arranged in three sections.

Calcium Antagonism in Heart and Smooth Muscle

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Author :
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 428 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Calcium Antagonism in Heart and Smooth Muscle by : Albrecht Fleckenstein

Download or read book Calcium Antagonism in Heart and Smooth Muscle written by Albrecht Fleckenstein and published by John Wiley & Sons. This book was released on 1983 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Secondary Prevention in Coronary Artery Disease and Myocardial Infarction

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Publisher : Springer Science & Business Media
ISBN 13 : 9400950241
Total Pages : 332 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Secondary Prevention in Coronary Artery Disease and Myocardial Infarction by : P. Mathes

Download or read book Secondary Prevention in Coronary Artery Disease and Myocardial Infarction written by P. Mathes and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite considerable effort in primary prevention, coronary heart disease continues to be the leading cause of death in the industrialized nations. The patient who survives his first myocardial infarction carries approximately a tenfold risk of recurrence and sudden death when compared to the normal population. The concept of secondary prevention, therefore, has emerged as an active strategy aimed at the reduction of fatal and non-fatal recurrences of myocardial infarction. Apart from risk factors of relevance in primary prevention, secondary prevention is dependent on the extent of the disease itself; in other words the number of vessels involved, the extent of myocar dial damage and the degree of electrical instability. Nonmedical aspects such as the level of education, the degree of social support and the attitude towards stress also appear to influence the prognosis. The aim of this volume is to bring together all those factors relevant to achieving the maximal life span in patients afflicted with a disease that by its very nature is a lifelong process. However, as the late Paul Dudley White stated appropriately more than 40 years ago, it is not sufficient merely to add years to a life, one should also add life to the years. This concept truly is the nucleus of secondary prevention, sine only a life worth living generates the motivitation needed to take all the steps necessary in secondary pre vention. The authors and the editor are most grateful to Pharma Schwarz Inc.

Pharmacology of Antihypertensive Drugs

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Publisher : Elsevier
ISBN 13 : 148325724X
Total Pages : 386 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Pharmacology of Antihypertensive Drugs by : P.A. Van Zwieten

Download or read book Pharmacology of Antihypertensive Drugs written by P.A. Van Zwieten and published by Elsevier. This book was released on 2013-10-22 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Hypertension, Volume 3: Pharmacology of Antihypertensive Drugs presents the biological and clinical knowledge in the field of hypertension. This book discusses the fundamental pharmacology of antihypertensive drugs. Organized into 12 chapters, this volume begins with an overview of the classification of antihypertensive mechanisms of drugs. This text then examines the effects of antihypertensive drugs in animal models and discusses the importance of these models and responses to human hypertension. Other chapters consider the pharmacological basis for the treatment of hypertension. This book discusses as well the various classes of antihypertensive drugs, which depends on two factors. The final chapter deals with the inhibitors of angiotensin-converting enzyme, which are essential in the drug treatment of hypertensive disease. This book is a valuable resource for clinicians, pharmacists, physiologists, epidemiologists, biological scientists, and general practitioners. Clinical investigators and medical students will also find this book extremely useful.

Cerebral Ischemia and Calcium

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Publisher : Springer Science & Business Media
ISBN 13 : 3642858635
Total Pages : 590 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Cerebral Ischemia and Calcium by : Alexander Hartmann

Download or read book Cerebral Ischemia and Calcium written by Alexander Hartmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although many books deal with isolated problems of calcium disturbance in relation to cardiac and cerebral function, this is the first to focus specifically on calcium metabolism and cerebral ischemia. Internationally acknowledged experts present recent data and new concepts in an interdisciplinary approach to the subject. They examine basic information on the pathophysiology of cellular events, the damage caused by excitotoxic substances, and the effects of calcium antagonistic drugs as measured in experimental animals. These contributions may help lead to possible therapeutic interference for the prevention of calcium imbalance.

Antihypertensive Drugs

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Publisher : CRC Press
ISBN 13 : 9789057021220
Total Pages : 558 pages
Book Rating : 4.0/5 (212 download)

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Book Synopsis Antihypertensive Drugs by : Zweten

Download or read book Antihypertensive Drugs written by Zweten and published by CRC Press. This book was released on 1997-09-05 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: Twenty US and European contributors from academia and pharmaceutical companies present a tripartite discussion of the short but impressive history of drug treatment of essential hypertension, focusing on: medicinal chemistry, pharmacology, and the clinical picture. Each successive generation of drugs (e.g. beta-blockers, calcium antagonists, and ACE-inhibitors) permits more precise tailoring to individual patient needs, as well as further elucidating the pathophysiology of the disease. Those interested in integrative medicine will appreciate the paper on treating hypertension in the elderly and diabetics, which refers to non-drug lifestyle approaches to lowering blood pressure. Annotation copyrighted by Book News, Inc., Portland, OR

Intracellular Calcium Regulation

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Publisher : Manchester University Press
ISBN 13 : 9780719018350
Total Pages : 504 pages
Book Rating : 4.0/5 (183 download)

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Book Synopsis Intracellular Calcium Regulation by : Hermann Bader

Download or read book Intracellular Calcium Regulation written by Hermann Bader and published by Manchester University Press. This book was released on 1986 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Calcium Entry Blockers in Cardiovascular and Cerebral Dysfunctions

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Publisher : Springer Science & Business Media
ISBN 13 : 9400960336
Total Pages : 313 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Calcium Entry Blockers in Cardiovascular and Cerebral Dysfunctions by : T. Godfraind

Download or read book Calcium Entry Blockers in Cardiovascular and Cerebral Dysfunctions written by T. Godfraind and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: 2 The free internal Ca+ concentration in human red cells is set according to the leak 2 and-pump principle: There is a finite passive Ca+ influx at the physiological 2 2 Ca+ -gradient across the membrane which is compensated by Ca+ pumping in the outward direction with a rate given by the degree of saturation of the A TP-fuelled Ca 2 pump at the steady-state internal Ca+ concentration. Simons (1982) recently devised a method allowing the measurement of the steady 2 2 state internal Ca+ concentration. Cells are suspended in media of different Ca+ con 2 2 tent whose Ca+ concentration is monitored by a Ca+ -selective electrode. When the cells are lysed (by digitonin) there is an upward or downward deflection of the elec 2 trode signal. At the point of zero deflection, the cellular Ca+ concentration equals that 2 of the medium. The result is, that in fresh human red blood cells the Ca+ concentra tion is ;;;; O.4,uM (this is an upper estimate; the true value may be considerably lower).

The Emergence of Drugs which Block Calcium Entry

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Publisher : Springer Science & Business Media
ISBN 13 : 3642732283
Total Pages : 163 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis The Emergence of Drugs which Block Calcium Entry by : Ronald D. Smith

Download or read book The Emergence of Drugs which Block Calcium Entry written by Ronald D. Smith and published by Springer Science & Business Media. This book was released on 2013-03-07 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium Entry Blockers (CEBs) are a new class of drugs which have been pushing back the frontiers of science and medicine for almost two decades. This report reviews some of the wealth of chemical, biological and clinical data describing the discovery and development of these compounds. The scientific importance, therapeutic benefit and marketing potential of these compounds have caused an explosion of scientific literature describing their effects in many preclinical and clinical settings. The definitional characteristics of these compounds suggest a certain predictability of their biological profile but their therapeutic usefulness varies widely dependent upon their physical properties, net hemodynamic effects, duration of action and incidence of side effects. CEBs appear uniquely suited to the treatment of the underlying complexity of cardiovascular disease. The CEBs of the future may live up to the expectations of pathophysiologically based therapeutics and allow the heart and blood vessels to outlive the cells which they support. The development of CEBs is an evolving story of epic proportions and represents the cooperative efforts of individuals in all areas of science.