Caenorhabditis elegans: Cell Biology and Physiology

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Author :
Publisher : Academic Press
ISBN 13 : 0123948266
Total Pages : 475 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Caenorhabditis elegans: Cell Biology and Physiology by :

Download or read book Caenorhabditis elegans: Cell Biology and Physiology written by and published by Academic Press. This book was released on 2012-01-25 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second part of an updated edition of the classic Methods in Cell Biology, Volume 48, this book emphasizes diverse methods and technologies needed to investigate C. elegans, both as an integrated organism and as a model system for research inquiries in cell, developmental, and molecular biology, as well as in genetics and pharmacology. By directing its audience to tried-and-true and cutting-edge recipes for research, this comprehensive collection is intended to guide investigators of C. elegans for years to come. Diverse, up-to-date techniques covered will be useful to the broadening community of C. elegans researchers for years to come Chapters written by leaders in the field Tried and true methods deliver busy researchers a one-stop compendium of essential protocols

Caenorhibditus Elegans: Modern Biological Analysis of an Organism

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Author :
Publisher : Academic Press
ISBN 13 : 0080859461
Total Pages : 687 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Caenorhibditus Elegans: Modern Biological Analysis of an Organism by :

Download or read book Caenorhibditus Elegans: Modern Biological Analysis of an Organism written by and published by Academic Press. This book was released on 1995-10-16 with total page 687 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first of its kind, this laboratory handbook emphasizes diverse methods and technologies needed to investigate C. elegans, both as an integrated organism and as a model system for research inquiries in cell,developmental, and molecular biology, as well as in genetics and pharmacology. Four primary sections--Genetic and Culture Methods, Neurobiology, Cell and Molecular Biology, and Genomics and Informatics--reflect the cross-disciplinary nature of C. elegans research. Because C. elegans is a simple and malleable organism with a small genome and few cell types, it provides an elegant demonstration of functions fundamental to multicellular organisms. The discipline has greatly expanded as researchers continue to find this small soil nematode to be the model of choice for studying specific pathways, stages of development, and cell types. By directing its audience not just to tried-and-true recipes for research, but also to databases and other innovative sources of information, this comprehensive collection is intended to guide investigators of C. elegans for years to come. First single-source book detailing explanations of current and classic C. elegans methodologies Diversity and scope of techniques covered expected to be useful to the broadening community of C. elegans researchers for years to come Techniques range from reverse genetics and mutagenesis, to laser ablation and electrophysiology, to in situ hybridization and DNA sequencing methods Appendices include resource information important to the C. elegans community, including the C. elegans Genetics Center and Internet resources like the Worm Community System and ACeDB Illustrated with more than 100 tables and figures

C. elegans

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Author :
Publisher : Humana
ISBN 13 : 9781071621806
Total Pages : 388 pages
Book Rating : 4.6/5 (218 download)

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Book Synopsis C. elegans by : Gal Haspel

Download or read book C. elegans written by Gal Haspel and published by Humana. This book was released on 2022-03-24 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed new edition provides a guide for implementing a selection of novel techniques utilizing the pioneering organism, Caenorhabditis elegans, a vital discovery engine for the rules of life, from molecules and genes, through cellular physiology, metabolism and aging, neurobiology and behavior, to individuality and interaction with the environment. Beginning with two chapters offering practical advice for setting up research programs with C. elegans, either for a new research group or for a short-term project such as a teaching laboratory, the volume continues with numerous hands-on methodologies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, C. elegans: Methods and Applications, Third Edition offers the kind of clear guidance that will serve all researchers working with these vital and dynamic organisms.

Neuroglia in C. elegans

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Author :
Publisher : Biota Publishing
ISBN 13 : 1615046895
Total Pages : 66 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Neuroglia in C. elegans by : Randy F. Stout, Jr.

Download or read book Neuroglia in C. elegans written by Randy F. Stout, Jr. and published by Biota Publishing. This book was released on 2018-02-27 with total page 66 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nematode C. elegans is one of the most important model organisms for understanding neurobiology. Its completely mapped neural connectome of 302 neurons and fully characterized and stereotyped development have made it a prototype for understanding nervous system structure, development, and function. Fifty-six out of C. elegans' total of 959 somatic cells are classified as neuroglia. Although research on worm glia has lagged behind studies focused on neurons, there has been a steep upswing in interest during the past decade. Information arising from the recent burst of research on worm glia supports the idea that C. elegans will continue to be an important animal model for understanding glial cell biology. Since the developmental lineage of all cells was mapped, each glial cell in C. elegans is known by a specific name and has research associated with it. We list and describe the glia of the hermaphrodite form of C. elegans and summarize research findings relating to each glial cell. We hope this lecture provides an informative overview of worm glia to accompany the excellent and freely available online resources available to the worm research community.

International Review of Cell and Molecular Biology

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Publisher : Academic Press
ISBN 13 : 0123812577
Total Pages : 213 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis International Review of Cell and Molecular Biology by : Kwang W. Jeon

Download or read book International Review of Cell and Molecular Biology written by Kwang W. Jeon and published by Academic Press. This book was released on 2010-08-24 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Impact factor for 2008: 4.935. Authored by some of the foremost scientists in the field Provides up-to-date information and directions for future research Valuable reference material for advanced undergraduates, graduate students and professional scientists

Comparative Biology of Aging

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Publisher : Springer Science & Business Media
ISBN 13 : 904813465X
Total Pages : 397 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Comparative Biology of Aging by : Norman S. Wolf

Download or read book Comparative Biology of Aging written by Norman S. Wolf and published by Springer Science & Business Media. This book was released on 2010-01-08 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: determined by an inability to move in response to touch. C. elegans develop through four larval stages following hatching and prior to adulthood. Adult C. elegans are reproductive for about the rst week of adulthood followed by approximately two weeks of post-reproductive adulthood prior to death. Life span is most commonly measured in the laboratory by maintaining the worms on the surface of a nutrie- agar medium (Nematode Growth Medium, NGM) with E. coli OP50 as the bacterial food source (REF). Alternative culture conditions have been described in liquid media; however, these are not widely used for longevity studies. Longevity of the commonly used wild type C. elegans hermaphrodite (N2) varies ? from 16 to 23 days under standard laboratory conditions (20 C, NGM agar, E. coli OP50 food source). Life span can be increased by maintaining animals at lower ambient temperatures and shortened by raising the ambient temperature. Use of a killed bacterial food source, rather than live E. coli, increases lifespan by 2–4 days, and growth of adult animals in the absence of bacteria (axenic growth or bac- rial deprivation) increases median life span to 32–38 days [3, 23, 24]. Under both standard laboratory conditions and bacterial deprivation conditions, wild-derived C. elegans hermaphrodites exhibit longevity comparable to N2 animals [25].

Mechanotransduction

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Publisher : Academic Press
ISBN 13 : 0123983274
Total Pages : 404 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Mechanotransduction by :

Download or read book Mechanotransduction written by and published by Academic Press. This book was released on 2014-07-29 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Molecular Biology and Translational Science provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their fields and abundant references. Volume 126 features in-depth reviews that focus on the tools required to investigate mechanotransduction. Additional chapters focus on how we can use these tools to answer fundamental questions about the interaction of physical forces with cell biology, morphogenesis, and function of mature structures. Chapters in the volume are authored by a unique combination of cell biologists and engineers, providing a range of perspectives on mechanotransduction. Provides a unique combination of perspectives from biologists and engineers Engaging to people of many training backgrounds

Biochemistry and Cell Biology of Ageing: Part I Biomedical Science

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Author :
Publisher : Springer
ISBN 13 : 9811328358
Total Pages : 526 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Biochemistry and Cell Biology of Ageing: Part I Biomedical Science by : J. Robin Harris

Download or read book Biochemistry and Cell Biology of Ageing: Part I Biomedical Science written by J. Robin Harris and published by Springer. This book was released on 2019-02-18 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume in the Subcellular Biochemistry series will focus on the biochemistry and cellular biology of aging processes in human cells. The chapters will be written by experts in their respective fields and will focus on a number of the current key areas of research in subcellular aging research. Main topics for discussion are mitochondrial aging, protein homeostasis and aging and the genetic processes that are involved in aging. There will also be chapters that are dedicated to the study of the roles of a variety of vitamins and minerals on aging and a number of other external factors (microbiological, ROS, inflammation, nutrition). This book will provide the reader with a state of the art overview of the subcellular aging field. This book will be published in cooperation with a second volume that will discuss the translation of the cell biology of aging to a more clinical setting and it is hoped that the combination of these two volumes will bring a deeper understanding of the links between the cell and the body during aging.

Caenorhabditis Elegans

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Author :
Publisher :
ISBN 13 : 9780122405457
Total Pages : 659 pages
Book Rating : 4.4/5 (54 download)

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Book Synopsis Caenorhabditis Elegans by : Henry F. Epstein

Download or read book Caenorhabditis Elegans written by Henry F. Epstein and published by . This book was released on 1995 with total page 659 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first of its kind, this laboratory handbook emphasizes diverse methods and technologies needed to investigate C. elegans , both as an integrated organism and as a model system for research inquiries in cell, developmental, and molecular biology, as well as in genetics and pharmacology. Four primary sections--Genetic and Culture Methods, Neurobiology, Cell and Molecular Biology, and Genomics and Informatics--cross disciplines in this volume's integrated approach to C. elegans . Because C. elegans is a simple and malleable organism with a small genome and few cell types, it provides an elegant demonstration of functions fundamental to multicellular organisms. The discipline has expanded manyfold as researchers continue to find this small soil nematode to be the model of choice for studying specific pathways, stages of development, and cell types. By directing its audience not just to tried-and-true recipes for research, but also to databases and other innovative sources of information, this comprehensive collection is intended to guide investigators of C. elegans for years to come.

International Review of Cytology

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Author :
Publisher : Elsevier
ISBN 13 : 008047506X
Total Pages : 254 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis International Review of Cytology by : Kwang W. Jeon

Download or read book International Review of Cytology written by Kwang W. Jeon and published by Elsevier. This book was released on 2007-02-28 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Cytology presents current advances and comprehensive reviews in cell biology – both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. This volume contains articles on Mechanism of Depolymerization and Severing of Actin Filaments and Its Significance in Cytoskeletal Dynamics; Biology of Polycomb and Thrithorax Group Proteins; Cell and Molecular Biology of Transthyretin and Thyroid Hormones; and Development and Role of Tight Junctions in the Retinal Pigment Epithelium.

C. Elegans II

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Publisher : Firefly Books
ISBN 13 : 9780879695323
Total Pages : 1252 pages
Book Rating : 4.6/5 (953 download)

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Book Synopsis C. Elegans II by : Donald L. Riddle

Download or read book C. Elegans II written by Donald L. Riddle and published by Firefly Books. This book was released on 1997 with total page 1252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Defines the current status of research in the genetics, anatomy, and development of the nematode C. elegans, providing a detailed molecular explanation of how development is regulated and how the nervous system specifies varied aspects of behavior. Contains sections on the genome, development, neural networks and behavior, and life history and evolution. Appendices offer genetic nomenclature, a list of laboratory strain and allele designations, skeleton genetic maps, a list of characterized genes, a table of neurotransmitter assignments for specific neurons, and information on codon usage. Includes bandw photos. For researchers in worm studies, as well as the wider community of researchers in cell and molecular biology. Annotation copyrighted by Book News, Inc., Portland, OR

Cell Polarity 2

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Publisher : Springer
ISBN 13 : 3319144669
Total Pages : 228 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Cell Polarity 2 by : Klaus Ebnet

Download or read book Cell Polarity 2 written by Klaus Ebnet and published by Springer. This book was released on 2015-02-24 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work provides a state-of-the art overview on the most relevant aspects of cell polarity. Volume 2 discusses the physiological and pathophysiological relevance of cell polarity. It especially focuses on pathophysiological conditions in which one or several aspects of cell polarity are impaired, and in which a loss of cell polarity possibly contributes to disease (e.g. epithelial-to-mesenchymal transition in cancer, role of polarity proteins in cancer). Both volumes are intended for professors, group leaders and researchers in cell biology as well as for medical professionals working in anatomy, cell biology, physiology, pathology and tumor biology.

Current Topics in Developmental Biology

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Publisher : Elsevier
ISBN 13 : 0080465528
Total Pages : 305 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Current Topics in Developmental Biology by :

Download or read book Current Topics in Developmental Biology written by and published by Elsevier. This book was released on 2006-11-03 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Topics in Developmental Biology provides a comprehensive survey of the major topics in the field of developmental biology. These volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. The series has recently passed its 30-year mark, making it the longest-running forum for contemporary issues in developmental biology. Includes many descriptive figures Topics covered include Wnt signaling, controlling regulatory networks, cartilage growth plates, and more Latest volume in the series that covers seven reviews in 300 pages

Cilia: Model Organisms and Intraflagellar Transport

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Author :
Publisher : Academic Press
ISBN 13 : 0123813786
Total Pages : 423 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Cilia: Model Organisms and Intraflagellar Transport by :

Download or read book Cilia: Model Organisms and Intraflagellar Transport written by and published by Academic Press. This book was released on 2009-12-01 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cilia are highly conserved organelles that serve motile functions, sensory functions, or both. These organelles power cell movement, generate fluid flow in various organs, act as sensors of the extracellular environment and have been modified for various specialized tasks such as light reception and smell. Defects in these ubiquitous organelles lead to a broad array of human genetic disorders that range from polycystic kidney disease, retinal degeneration, epilepsy and infertility to developmental defects such as situs inversus and polydactyly. This volume is the third in a three-part series on cilia that focuses on the use of model organisms to gain insight into ciliary function and on the process of intraflagellar transport that is essential for the assembly and maintenance of ciliary structures. Includes both classic and state-of-the-art methods readily adaptable across model systems, and designed to last the test of time Covers forward and reverse genetic analysis of IFT and biochemical methods to define the role of IFT components Methods presented cover molecular, genetic, and biochemical approaches to ciliary function in model organisms

Cellular Aging and Cell Death

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Publisher : John Wiley & Sons
ISBN 13 : 9780471121237
Total Pages : 344 pages
Book Rating : 4.1/5 (212 download)

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Book Synopsis Cellular Aging and Cell Death by : Nikki J. Holbrook

Download or read book Cellular Aging and Cell Death written by Nikki J. Holbrook and published by John Wiley & Sons. This book was released on 1995-12-20 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular AGING AND CELL DEATH Edited by Nikki J. Holbrook, George R. Martin, and Richard A.Lockshin Cellular Aging and Cell Death provides a thorough understanding ofthe mechanisms responsible for cellular aging, covering the recentresearch on programmed cell death and senescence, and describingtheir role in the control of cell proliferation and the agingprocess. This one-of-a-kind book is the first to combine the twohottest research areas of cell biology into one comprehensivetext. Leading experts contribute to give readers an authoritativeoverview of the distinct fields of cellular aging and programmedcell death, as well as to demonstrate how both fields are criticalto understanding the aging process. They address the large andgrowing interest in apoptosis, especially with regard to themolecular signals that induce and regulate programmed cell death,and the role of apoptosis in a variety of age-associated diseasesand disabilities. Throughout the book, a strong emphasis is placedon the interrelationship of the molecular, cellular, andphysiological aspects of senescence. Individual chapters discuss such topics as the role and regulationof apoptosis in development, the potential impact of cell death onsuch postmitotic tissues as nerve and muscle, and suggest thatprogrammed cell death plays an important role in both pathologicaland nonpathological aspects of aging, including neurodegenerativediseases. One important chapter focuses on the most recent research involvingthe study of telomeres, whose reduction in length with age and celldivision may underlie cellular senescence. The subject of neuronalcell death is also put into the perspective of aging. Cellular Aging and Cell Death bridges the rapidly growing fields ofcellular aging and programmed cell death. This thorough, yetconcise book will be of particular interest to graduate studentsand researchers within the fields of cell and developmentalbiology, neurobiology, immunology, and physiology. Physicians andmedical students involved in the fields of gerontology andpathology will also find this an informative reference.

International Review of Cytology

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Author :
Publisher : Academic Press
ISBN 13 : 008056948X
Total Pages : 291 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis International Review of Cytology by :

Download or read book International Review of Cytology written by and published by Academic Press. This book was released on 2001-09-26 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Cytology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles in this volume include the role and distribution of retinoic acid during CNS development, the role of receptor-associated protein (RAP) as a molecular chaperone for members of the LDL receptor family, the biology of cortical granules, acetylcholinesterase genes in the nematode caenorhabditis elegans, and reciprocal regulation of endothelin-1 and nitric oxide. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. *The Role and Distribution of Retinoic Acid during CNS Development *The Roles of Receptor-Associated Protein (RAP) as a Molecular Chaperone for Members of the LDL Receptor Family *The Biology of Cortical Granules *Acetylcholinesterase Genes in the Namatode Caenorhabditis elegans *Receprocal Regulation of Endothelin-1 and Nitric Oxide: Relevance in the Physiology and Pathology of the Cardiovascular System

Current Topics in Developmental Biology

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Author :
Publisher : Elsevier
ISBN 13 : 0080490956
Total Pages : 274 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Current Topics in Developmental Biology by :

Download or read book Current Topics in Developmental Biology written by and published by Elsevier. This book was released on 2001-03-12 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the embryonic stage of a multicellular organism, precise arrangements of different cell types arise. These cell types eventually become the tissues and organs of the organism if it is an animal, for instance. Developmental biology is the study of this process in both plants and animals and covers the entire development stage of the organism. Current Topics in Developmental Biology provides a comprehensive survey of the major topics in this rapidly advancing field. The volumes are valuable to researchers in animal and plant development as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. With over thirty years of publication, this series is the longest-running forum for contemporary issues in developmental biology.