Burkitt Lymphoma. Forms, Effects, Risk Factors, Treatment

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Publisher : GRIN Verlag
ISBN 13 : 3668575886
Total Pages : 19 pages
Book Rating : 4.6/5 (685 download)

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Book Synopsis Burkitt Lymphoma. Forms, Effects, Risk Factors, Treatment by : Patrick Kimuyu

Download or read book Burkitt Lymphoma. Forms, Effects, Risk Factors, Treatment written by Patrick Kimuyu and published by GRIN Verlag. This book was released on 2017-11-21 with total page 19 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research Paper (postgraduate) from the year 2017 in the subject Health - Public Health, grade: 1, Egerton University, language: English, abstract: This research paper will provide an overview on Burkitt lymphoma disease and its pathophysiology. Burkitt lymphoma has become one of the most prevalent cancers in the past two decades in which the number of people with the disease has increased, especially in Africa. Research indicates that burkitt lymphoma has emerged to be the fastest growing tumor among humans. Burkitt lymphoma was identified in 1956 by Denis Burkitt, and it is one of the principal forms on non-Hodgkin’s lymphoma, which affect immune cells. Epidemiological reports indicate that, Burkitt lymphoma is more prevalent in malaria endemic regions than other regions although it greatest impact is experienced in Africa where it affects children who are also experiencing episodes of malaria and Epstein-Barr viral infection. Epstein-Barr virus is believed to be the principal cause of infectious mononucleosis, which leads to the transformation of B-cells into tumor cells, especially following malaria episode which weakens the immune system. This is probably the reason as to why 98% of Burkitt lymphoma cases in Africa are linked to Epstein-Barr infection. Elsewhere in the U.S, the incidence of Burkitt lymphoma accounts for about 1,200 people annually in which 59% of all the patients diagnosed with the disease being adults above the age of 40 years. In Burkitt lymphoma, lymphocytes, primarily the B-cells of the immune system which are involved in cell-mediated immune response during pathogenic infections are affected. In most cases, the prevalence of the disease is enhanced by infections which weaken the immune system. For instance, malaria, Epstein-Barr viral infection and HIV are some of the diseases associated with a decrease of the immune system response. In addition, therapies which are immune-suppressive, especially those involved in organ transplantation to prevent transplant rejection and highly-active antiretroviral therapy (HAART) used for HIV/AIDS treatment facilitate the formation of cancerous B-cells. However, the physiology and anatomy of Burkitt lymphoma encompasses diverse aspects compared to other forms cancer.

Human Herpesviruses

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Publisher : Cambridge University Press
ISBN 13 : 1139461648
Total Pages : 1325 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Human Herpesviruses by : Ann Arvin

Download or read book Human Herpesviruses written by Ann Arvin and published by Cambridge University Press. This book was released on 2007-08-16 with total page 1325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

Pediatric Lymphomas

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Publisher : Springer Science & Business Media
ISBN 13 : 354068753X
Total Pages : 296 pages
Book Rating : 4.5/5 (46 download)

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Book Synopsis Pediatric Lymphomas by : Howard J. Weinstein

Download or read book Pediatric Lymphomas written by Howard J. Weinstein and published by Springer Science & Business Media. This book was released on 2007-01-20 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive textbook of Hodgkin's and non-Hodgkin's lymphomas written by leaders in the field of childhood lymphomas. It includes clinical, pathologic and molecular biology of each subtype of lymphoma. The pathology chapters are comprehensive and include excellent photographs. The book is at the level of subspecialists in pediatric hematology and oncology, radiation oncology, pediatric surgery and hematopathology.

Childhood Cancer and Functional Impacts Across the Care Continuum

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Publisher :
ISBN 13 : 9780309683494
Total Pages : pages
Book Rating : 4.6/5 (834 download)

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Book Synopsis Childhood Cancer and Functional Impacts Across the Care Continuum by : National Academies of Sciences Engineering and Medicine

Download or read book Childhood Cancer and Functional Impacts Across the Care Continuum written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2021-09-09 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.

Cancer Incidence and Survival Among Children and Adolescents

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Publisher :
ISBN 13 :
Total Pages : 194 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis Cancer Incidence and Survival Among Children and Adolescents by :

Download or read book Cancer Incidence and Survival Among Children and Adolescents written by and published by . This book was released on 1999 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:

An Illustrated Guide to Pediatric Surgery

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Publisher : Springer
ISBN 13 : 331906665X
Total Pages : 589 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis An Illustrated Guide to Pediatric Surgery by : Ahmed H. Al-Salem

Download or read book An Illustrated Guide to Pediatric Surgery written by Ahmed H. Al-Salem and published by Springer. This book was released on 2014-09-24 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written in a simple point by point style for ease of use, this volume covers all aspects of pediatric surgery with emphasis on important points for diagnosis and management. Each chapter covers a topic with emphasis on the most common conditions in neonatal and general pediatric surgery. The text is well illustrated with clinical, operative, radiological, and histopathological color figures and illustrations. The book also presents some of the rare conditions encountered in pediatric surgery, as well as common pediatric urology conditions. An Illustrated Guide to Pediatric Surgery is a useful reference to pediatric surgeons, specialists, fellows and residents, as well as general surgeons, pediatricians, neonatologists, medical students and interns interested in pediatric surgery.

The Epstein-Barr Virus

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Publisher : Springer Science & Business Media
ISBN 13 : 3642672361
Total Pages : 467 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis The Epstein-Barr Virus by : M. A. Epstein

Download or read book The Epstein-Barr Virus written by M. A. Epstein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Epstein-Barr virus was discovered 15 years ago. Since that time an immense body of information has been accumu lated on this agent which has come to assume great signifi cance in many different fields of biological science. Thus, the virus has very special relevance in human medicine and oncology, in tumor virology, in immunology, and in mole cular virology, since it is the cause of infectious mononu cleosis and also the first human cancer virus, etiologically related to endemic Burkitt's lymphoma and probably to nasopharyngeal carcinoma. In addition, continuous human lymphoid cell lines initiated and maintained by the transform ing function of the virus genome provide a laboratory tool with wide and ever-growing applications. Innumerable papers on the Epstein-Barr virus have ap peared over recent years and reports of work with this agent now constitute a veritable flood. The present book provides the first and only comprehensive, authoritative over-view of all aspects of the virus by authors who have been the original and major contributors in their particular disciplines. A complete and up-to-date survey of this unique and important agent is thus provided which should be of great interest to experts, teachers, and students engaged in cancer research, virology, immunology, molecular biology, epide miology, and cell culture. Where topics have been dealt with from more than one of these viewpoints, some inevitable overlap and duplication has resulted; although this has been kept to a minimum, it has been retained in some places because of positive usefulness.

Introduction to Lymphoma

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Publisher :
ISBN 13 : 9781914948060
Total Pages : 0 pages
Book Rating : 4.9/5 (48 download)

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Book Synopsis Introduction to Lymphoma by :

Download or read book Introduction to Lymphoma written by and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Childhood Acute Lymphoblastic Leukemia

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Publisher : Springer
ISBN 13 : 3319397087
Total Pages : 345 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Childhood Acute Lymphoblastic Leukemia by : Ajay Vora

Download or read book Childhood Acute Lymphoblastic Leukemia written by Ajay Vora and published by Springer. This book was released on 2017-04-21 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.

The Heterogeneity of Cancer Metabolism

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Publisher : Springer
ISBN 13 : 331977736X
Total Pages : 186 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis The Heterogeneity of Cancer Metabolism by : Anne Le

Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

Hematology

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Publisher :
ISBN 13 : 9780443066283
Total Pages : 2821 pages
Book Rating : 4.0/5 (662 download)

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Book Synopsis Hematology by : Ronald Hoffman

Download or read book Hematology written by Ronald Hoffman and published by . This book was released on 2005 with total page 2821 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Young Person's Guide to Lymphoma

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Publisher :
ISBN 13 : 9780953724420
Total Pages : 0 pages
Book Rating : 4.7/5 (244 download)

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Book Synopsis A Young Person's Guide to Lymphoma by : Chrissie Williams

Download or read book A Young Person's Guide to Lymphoma written by Chrissie Williams and published by . This book was released on 2001 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neurologic Complications of Cancer

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Publisher : OUP USA
ISBN 13 : 0195366743
Total Pages : 652 pages
Book Rating : 4.1/5 (953 download)

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Book Synopsis Neurologic Complications of Cancer by : Lisa M. DeAngelis

Download or read book Neurologic Complications of Cancer written by Lisa M. DeAngelis and published by OUP USA. This book was released on 2009 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patients with cancer can suffer from a bewildering variety of neurologic signs and symptoms. The neurologic symptoms are often more disabling than the primary cancer. Symptoms including confusion, seizures, pain and paralysis may be a result of either metastases to the nervous system or one of several nonmetastatic complications of cancer. The physician who promptly recognizes neurologic symptoms occurring in a patient with cancer and makes an early diagnosis may prevent the symptoms from becoming permanently disabling or sometimes lethal. This monograph, an update of the first edition published in 1995, is divided into 3 sections. The first classifies the wide variety of disorders that can cause neurologic symptoms the patient with cancer, discusses the pathophysiology of nervous system metastases, the pathophysiology and treatment of brain edema and the approach to supportive care of common neurologic symptoms such as seizures, pain, and side effects of commonly used supportive care agents. The second section is devoted to nervous system metastases, addressing in turn, brain, spinal cord, meningeal and cranial and peripheral nerve metastases, describing clinical symptoms, approach to diagnosis and current treatment. The third section addresses several nonmetastatic complications of cancer and includes sections on vascular disease, infections, metabolic and nutritional disorders, side chemotherapy, radiation and other diagnostic and therapeutic procedures. The final chapter addresses paraneoplastic syndromes.The book is intended for practicing oncologists, neurologists, neurosurgeons and radiation oncologists as well as internists who treated patients with cancer. Our attempt was to write a book that would assist oncologists in understanding neurologic problems and neurologists in understanding oncologic problems. The book is also intended for physicians training to specialize in any of the above areas. It includes a practical approach to the diagnosis and management of patients with neurologic disease who are with known to have cancer or in whom cancer is suspected.

Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues

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Publisher : IARC
ISBN 13 : 9789283224112
Total Pages : 360 pages
Book Rating : 4.2/5 (241 download)

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Book Synopsis Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues by : World Health Organization

Download or read book Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues written by World Health Organization and published by IARC. This book was released on 2001 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the third volume in the new World Health Organization series on histological and genetic typing of tumours. Tumours of the haematopoietic and lymphoid tissues are covered. This was a collaborative project of the European Association for Haematolpathology and the Society for Haematopathology and others. The WHO classification is based on the principles defined in the Revised European-American Classification of Lymphoid Neoplasms (REAL) classification. Over 50 pathologists from around the world were involved in the project and proponents of all major lymphoma and leukaemia classifications have agreed to accept the WHO as the standard classification of haematological malignancies. So this classification represents the first true world wide concensus of haematologic malignancies. Colour photographs, magnetic resonance and ultrasound images and CT scans are included.

Aggressive Lymphomas

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Publisher : Springer
ISBN 13 : 3030003620
Total Pages : 358 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Aggressive Lymphomas by : Georg Lenz

Download or read book Aggressive Lymphomas written by Georg Lenz and published by Springer. This book was released on 2018-12-27 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes current knowledge of the biology and molecular pathogenesis of aggressive lymphomas and reviews the state of the art in diagnostic and therapeutic strategies. The aim is both to provide the reader with a sound understanding of the very significant progress that has been achieved in the understanding and management of these malignancies over recent years and to facilitate appropriate choice of the therapeutic strategy in individual cases. The assessment of different prognostic parameters are clearly presented in order to permits effective risk stratification that impacts on treatment choice. Recent insights into lymphomagenesis are exemplified and may assist in identifying emerging therapeutic targets. The comprehensive and up-to-date nature of the book will make it an ideal reference for all physicians and researchers interested in lymphoma, including clinicians from various medical specialties, biologists, pathologists, radiologists and nuclear medicine specialist, as well as students.

WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues

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Publisher : IARC Who Classification of Tum
ISBN 13 : 9789283244943
Total Pages : 586 pages
Book Rating : 4.2/5 (449 download)

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Book Synopsis WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues by : E. Campo

Download or read book WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues written by E. Campo and published by IARC Who Classification of Tum. This book was released on 2017-09-18 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues is a Revised Fourth Edition of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants further include new ICD-O codes, epidemiology, clinical features, macroscopy, prognosis, and predictive factors. This classification, prepared by 132 authors from 23 countries, contains about 1300 color images and tables and more than 4500 references.

Cancer in Sub-Saharan Africa

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Publisher : IARC Scientific Publications
ISBN 13 : 9789283222200
Total Pages : 0 pages
Book Rating : 4.2/5 (222 download)

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Book Synopsis Cancer in Sub-Saharan Africa by : D. M. Parkin

Download or read book Cancer in Sub-Saharan Africa written by D. M. Parkin and published by IARC Scientific Publications. This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cancer in Sub-Saharan Africa volume brings together population-based cancer incidence data from 25 cancer registries in 20 sub-Saharan African countries that are part of the African Cancer Registry Network. The compiled data in this volume, presented and commented upon by covered population and by anatomical site, are of tremendous value to the assessment of the pattern and evolution of cancer in Africa, as a means of elucidating, confirming, and evaluating causes of the disease.