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Mutagenic Impurities

Author : Andrew Teasdale
Publisher : John Wiley & Sons
ISBN 13 : 1119551218
Total Pages : 548 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Mutagenic Impurities by : Andrew Teasdale

Download or read book Mutagenic Impurities written by Andrew Teasdale and published by John Wiley & Sons. This book was released on 2022-02-15 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn to implement effective control measures for mutagenic impurities in pharmaceutical development In Mutagenic Impurities: Strategies for Identification and Control, distinguished chemist Andrew Teasdale delivers a thorough examination of mutagenic impurities and their impact on the pharmaceutical industry. The book incorporates the adoption of the ICH M7 guideline and focuses on mutagenic impurities from both a toxicological and analytical perspective. The editor has created a primary reference for any professional or student studying or working with mutagenic impurities and offers readers a definitive narrative of applicable guidelines and practical, tested solutions. It demonstrates the development of effective control measures, including chapters on the purge tool for risk assessment. The book incorporates a discussion of N-Nitrosamines which was arguably the largest mutagenic impurity issue ever faced by the pharmaceutical industry, resulting in the recall of Zantac and similar drugs resulting from N-Nitrosamine contamination. Readers will also benefit from the inclusion of: A thorough introduction to the development of regulatory guidelines for mutagenic and genotoxic impurities, including a historical perspective on the development of the EMEA guidelines and the ICH M7 guideline An exploration of in silico assessment of mutagenicity, including use of structure activity relationship evaluation as a tool in the evaluation of the genotoxic potential of impurities A discussion of a toxicological perspective on mutagenic impurities, including the assessment of mutagenicity and examining the mutagenic and carcinogenic potential of common synthetic reagents Perfect for chemists, analysts, and regulatory professionals, Mutagenic Impurities: Strategies for Identification and Control will also earn a place in the libraries of toxicologists and clinical safety scientists seeking a one-stop reference on the subject of mutagenic impurity identification and control.

Impacts of climate change on fisheries and aquaculture

Author : Food and Agriculture Organization of the United Nations
Publisher : Food & Agriculture Org.
ISBN 13 : 9251306079
Total Pages : 654 pages
Book Rating : 4.2/5 (513 download)

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Book Synopsis Impacts of climate change on fisheries and aquaculture by : Food and Agriculture Organization of the United Nations

Download or read book Impacts of climate change on fisheries and aquaculture written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2019-01-06 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report indicates that climate change will significantly affect the availability and trade of fish products, especially for those countries most dependent on the sector, and calls for effective adaptation and mitigation actions encompassing food production.

Bwa Yo

Author : Joel Timyan
Publisher :
ISBN 13 :
Total Pages : 440 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Bwa Yo by : Joel Timyan

Download or read book Bwa Yo written by Joel Timyan and published by . This book was released on 1996 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Jellyfish and Polyps

Author : Antonella Leone
Publisher : MDPI
ISBN 13 : 3039432087
Total Pages : 230 pages
Book Rating : 4.0/5 (394 download)

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Book Synopsis Jellyfish and Polyps by : Antonella Leone

Download or read book Jellyfish and Polyps written by Antonella Leone and published by MDPI. This book was released on 2020-11-20 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue of Marine Drugs gathers recent investigations on the proteomes, metabolomes, transcriptomes, and the associated microbiomes of marine jellyfish and polyps, including bioactivity studies of their compounds and more generally, on their biotechnological potential, witnessing the increasingly recognized importance of Cnidaria as a largely untapped Blue Growth resource for new drug discovery. These researches evoke the outstanding ecological importance of cnidarians in marine ecosystems worldwide, calling for a global monitoring and conservation of marine biodiversity, so that the biotechnological exploitation of marine living resources will be carried out to conserve and sustainably use the natural capital of the oceans.

Genotoxic Impurities

Author : Andrew Teasdale
Publisher : John Wiley & Sons
ISBN 13 : 0470934751
Total Pages : 455 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Genotoxic Impurities by : Andrew Teasdale

Download or read book Genotoxic Impurities written by Andrew Teasdale and published by John Wiley & Sons. This book was released on 2011-03-29 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines genotoxic impurities and their impact on the pharmaceutical industry. Specific sections examine this from both a toxicological and analytical perspective. Within these sections, the book defines appropriate strategies to both assess and ultimately control genotoxic impurities, thus aiding the reader to develop effective control measures. An opening section covers the development of guidelines and the threshold of toxicological concern (TTC) and is followed by a section on safety aspects, including safety tests in vivo and vitro, and data interpretation. The second section addresses the risk posed by genotoxic impurities from outside sources and from mutagens within DNA. In the final section, the book deals with the quality perspective of genotoxic impurities focused on two critical aspects, the first being the analysis and the second how to practically evaluate the impurities.

Fire Across the Desert

Author : Peter Morton
Publisher :
ISBN 13 :
Total Pages : 616 pages
Book Rating : 4.X/5 (1 download)

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Book Synopsis Fire Across the Desert by : Peter Morton

Download or read book Fire Across the Desert written by Peter Morton and published by . This book was released on 1989 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Sediment Dynamics and Pollutant Mobility in Rivers

Author : Bernd Westrich
Publisher : Springer Science & Business Media
ISBN 13 : 3540347852
Total Pages : 463 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Sediment Dynamics and Pollutant Mobility in Rivers by : Bernd Westrich

Download or read book Sediment Dynamics and Pollutant Mobility in Rivers written by Bernd Westrich and published by Springer Science & Business Media. This book was released on 2007-10-11 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first interdisciplinary book on the mobilization of nutrients and pollutants in the water phase due to hydrodynamic processes. Coverage includes the formation of aggregates in turbulent water; flocks and biofilms from organic reactions; and the formation of new surfaces for re-adsorption of dissolved pollutants. The book gathers papers resulting from an International Symposium on Sediment Dynamics and Pollutant Mobility in River Basins in Hamburg, Germany, March, 2006.

WHO Monographs on Selected Medicinal Plants

Author : World Health Organization
Publisher : World Health Organization
ISBN 13 : 9789241545372
Total Pages : 392 pages
Book Rating : 4.5/5 (453 download)

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Book Synopsis WHO Monographs on Selected Medicinal Plants by : World Health Organization

Download or read book WHO Monographs on Selected Medicinal Plants written by World Health Organization and published by World Health Organization. This book was released on 1999 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second volume in a series of monographs which are intended to promote information exchange and international harmonised standards for the quality control and use of herbal medicines. It contains scientific information on 30 selected plants, and each entry includes a pharmacopoeial summary for quality assurance purposes, information on its clinical application and sections on contraindications, pharmacology, safety issues, and dosage forms. It provides two cumulative indexes with entries in alphabetical order by plant name and according to the plant material of interest.

Carbon Sequestration Potential of Agroforestry Systems

Author : B. Mohan Kumar
Publisher : Springer Science & Business Media
ISBN 13 : 9400716303
Total Pages : 317 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Carbon Sequestration Potential of Agroforestry Systems by : B. Mohan Kumar

Download or read book Carbon Sequestration Potential of Agroforestry Systems written by B. Mohan Kumar and published by Springer Science & Business Media. This book was released on 2011-08-05 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tree based production systems abound especially in the tropics. Despite the pervasiveness of such multipurpose “trees-outside-forest” resources, they have not attracted adequate attention in the development paradigms of many nation states. These multispecies production systems impact the ecosystem processes favourably. Yet, our understanding of the diversity attributes and carbon dynamics under agroforestry is not adequate. This book focuses on the role of multispecies production systems involving tree and crop species as a means for carbon sequestration and thereby reduce atmospheric carbon dioxide levels. Sixteen chapters organized into three broad sections titled: Measurement and Estimation, Agrobiodiversity and Tree Management, and Policy and Socioeconomic Aspects represent a cross section of the opportunities and challenges in current research and emerging issues in harnessing carbon sequestration potential of agroforestry systems.

Introduction to Business Statistics

Author : Ronald M. Weiers
Publisher : South Western Educational Publishing
ISBN 13 : 9780324381443
Total Pages : 853 pages
Book Rating : 4.3/5 (814 download)

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Book Synopsis Introduction to Business Statistics by : Ronald M. Weiers

Download or read book Introduction to Business Statistics written by Ronald M. Weiers and published by South Western Educational Publishing. This book was released on 2008 with total page 853 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highly praised for its clarity and great examples, Weiers' INTRODUCTION TO BUSINESS STATISTICS, 6E introduces fundamental statistical concepts in a conversational language that connects with today's students. Even those intimidated by statistics quickly discover success with the book's proven learning aids, outstanding illustrations, non-technical terminology, and hundreds of current examples drawn from real-life experiences familiar to students. A continuing case and contemporary applications combine with more than 100 new or revised exercises and problems that reflect the latest changes in business today with an accuracy you can trust. You can easily introduce today's leading statistical software and teach not only how to complete calculations by hand and using Excel, but also how to determine which method is best for a particular task. The book's student-oriented approach is supported with a wealth of resources, including the innovative new CengageNOW online course management and learning system that saves you time while helping students master the statistical skills most important for business success.

Livestock and the Environment

Author : Ralph H. Ramsey
Publisher :
ISBN 13 :
Total Pages : 150 pages
Book Rating : 4.:/5 (3 download)

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Book Synopsis Livestock and the Environment by : Ralph H. Ramsey

Download or read book Livestock and the Environment written by Ralph H. Ramsey and published by . This book was released on 1975 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Phosphorus Loss from Soil to Water

Author : H. Tunney
Publisher : Cabi
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Phosphorus Loss from Soil to Water by : H. Tunney

Download or read book Phosphorus Loss from Soil to Water written by H. Tunney and published by Cabi. This book was released on 1997 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eutrophication, caused by phosphorus enrichment, is not a new environmental problem. The persistence of eutrophication in an era when many point-source phosphorus inputs have been curtailed has turned the focus of attention to agricultural phosphorus. A workshop was held in Ireland in 1995 to discuss factors controlling phosphorus losses to water from agriculture. This book presents the proceedings of the workshop and consists of 18 chapters by the invited speakers and three chapters with the 45 poster papers displayed at the workshop.

The Foundations of Statistics

Author : Leonard J. Savage
Publisher : Courier Corporation
ISBN 13 : 0486137104
Total Pages : 341 pages
Book Rating : 4.4/5 (861 download)

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Book Synopsis The Foundations of Statistics by : Leonard J. Savage

Download or read book The Foundations of Statistics written by Leonard J. Savage and published by Courier Corporation. This book was released on 2012-08-29 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Classic analysis of the foundations of statistics and development of personal probability, one of the greatest controversies in modern statistical thought. Revised edition. Calculus, probability, statistics, and Boolean algebra are recommended.

Challenges and Opportunities for Agricultural Intensification of the Humid Highland Systems of Sub-Saharan Africa

Author : Bernard Vanlauwe
Publisher : Springer
ISBN 13 : 3319076620
Total Pages : 399 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Challenges and Opportunities for Agricultural Intensification of the Humid Highland Systems of Sub-Saharan Africa by : Bernard Vanlauwe

Download or read book Challenges and Opportunities for Agricultural Intensification of the Humid Highland Systems of Sub-Saharan Africa written by Bernard Vanlauwe and published by Springer. This book was released on 2014-10-07 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: The humid highlands in sub-Saharan Africa (SSA) are characterized by high population densities and require intensification. The Consortium for Improving Agriculture-based Livelihoods in Central Africa (CIALCA) has set up a research for development platform in various mandate areas in DR Congo, Burundi, and Rwanda, aiming to identify improved production, market, and nutrition options and facilitating the access for development partners to these options. This platform is supported by capacity building, multi-stakeholder dialogue, and monitoring and evaluation efforts. The conference, facilitated by CIALCA, aimed to (i) take stock of the state-of the art in agricultural intensification in the highlands of SSA and (ii) chart the way forward for agricultural research for development in the humid highlands of SSA, and more specifically in the recently launched Humidtropics Consortium Research Programme, through keynote, oral and poster presentations, and strategic panel discussions.

The Cambridge Handbook of Infant Development

Author : Jeffrey J. Lockman
Publisher : Cambridge University Press
ISBN 13 : 1108663001
Total Pages : 1104 pages
Book Rating : 4.1/5 (86 download)

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Book Synopsis The Cambridge Handbook of Infant Development by : Jeffrey J. Lockman

Download or read book The Cambridge Handbook of Infant Development written by Jeffrey J. Lockman and published by Cambridge University Press. This book was released on 2020-08-13 with total page 1104 pages. Available in PDF, EPUB and Kindle. Book excerpt: This multidisciplinary volume features many of the world's leading experts of infant development, who synthesize their research on infant learning and behaviour, while integrating perspectives across neuroscience, socio-cultural context, and policy. It offers an unparalleled overview of infant development across foundational areas such as prenatal development, brain development, epigenetics, physical growth, nutrition, cognition, language, attachment, and risk. The chapters present theoretical and empirical depth and rigor across specific domains of development, while highlighting reciprocal connections among brain, behavior, and social-cultural context. The handbook simultaneously educates, enriches, and encourages. It educates through detailed reviews of innovative methods and empirical foundations and enriches by considering the contexts of brain, culture, and policy. This cutting-edge volume establishes an agenda for future research and policy, and highlights research findings and application for advanced students, researchers, practitioners, and policy-makers with interests in understanding and promoting infant development.

Intuitive Probability and Random Processes using MATLAB®

Author : Steven Kay
Publisher : Springer Science & Business Media
ISBN 13 : 0387241582
Total Pages : 838 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Intuitive Probability and Random Processes using MATLAB® by : Steven Kay

Download or read book Intuitive Probability and Random Processes using MATLAB® written by Steven Kay and published by Springer Science & Business Media. This book was released on 2006-03-20 with total page 838 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intuitive Probability and Random Processes using MATLAB® is an introduction to probability and random processes that merges theory with practice. Based on the author’s belief that only "hands-on" experience with the material can promote intuitive understanding, the approach is to motivate the need for theory using MATLAB examples, followed by theory and analysis, and finally descriptions of "real-world" examples to acquaint the reader with a wide variety of applications. The latter is intended to answer the usual question "Why do we have to study this?" Other salient features are: *heavy reliance on computer simulation for illustration and student exercises *the incorporation of MATLAB programs and code segments *discussion of discrete random variables followed by continuous random variables to minimize confusion *summary sections at the beginning of each chapter *in-line equation explanations *warnings on common errors and pitfalls *over 750 problems designed to help the reader assimilate and extend the concepts Intuitive Probability and Random Processes using MATLAB® is intended for undergraduate and first-year graduate students in engineering. The practicing engineer as well as others having the appropriate mathematical background will also benefit from this book. About the Author Steven M. Kay is a Professor of Electrical Engineering at the University of Rhode Island and a leading expert in signal processing. He has received the Education Award "for outstanding contributions in education and in writing scholarly books and texts..." from the IEEE Signal Processing society and has been listed as among the 250 most cited researchers in the world in engineering.

World Congress on Medical Physics and Biomedical Engineering 2018

Author : Lenka Lhotská
Publisher :
ISBN 13 : 9789811090363
Total Pages : pages
Book Rating : 4.0/5 (93 download)

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Book Synopsis World Congress on Medical Physics and Biomedical Engineering 2018 by : Lenka Lhotská

Download or read book World Congress on Medical Physics and Biomedical Engineering 2018 written by Lenka Lhotská and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the proceedings of the IUPESM World Congress on Biomedical Engineering and Medical Physics, a tri-annual high-level policy meeting dedicated exclusively to furthering the role of biomedical engineering and medical physics in medicine. The book offers papers about emerging issues related to the development and sustainability of the role and impact of medical physicists and biomedical engineers in medicine and healthcare. It provides a unique and important forum to secure a coordinated, multileveled global response to the need, demand, and importance of creating and supporting strong academic and clinical teams of biomedical engineers and medical physicists for the benefit of human health.