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Author : Saverio Cinti
Publisher :
ISBN 13 : 9788885030329
Total Pages : 94 pages
Book Rating : 4.0/5 (33 download)
Download or read book The Adipose Organ written by Saverio Cinti and published by . This book was released on 1999 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Rubén Cereijo
Publisher : Frontiers Media SA
ISBN 13 : 2832534007
Total Pages : 139 pages
Book Rating : 4.8/5 (325 download)
Download or read book Novel regulatory mechanisms behind thermogenesis of brown and beige adipocytes written by Rubén Cereijo and published by Frontiers Media SA. This book was released on 2023-09-19 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Alexander Pfeifer
Publisher : Springer
ISBN 13 : 303010513X
Total Pages : 424 pages
Book Rating : 4.0/5 (31 download)
Download or read book Brown Adipose Tissue written by Alexander Pfeifer and published by Springer. This book was released on 2019-04-02 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main focus of this book is on brown adipose tissue and its metabolic function. The book provides a timely update on the latest research and shows where the field is heading. Brown adipose tissue (BAT) dissipates energy and has received considerable attention in the last few years, having been re-discovered in adult humans in 2007/9. Moreover, BAT might offer a target for novel therapies to address obesity, a health condition that has reached pandemic dimensions.
Author : Carsten Carlberg
Publisher : Springer Nature
ISBN 13 : 303036948X
Total Pages : 195 pages
Book Rating : 4.0/5 (33 download)
Download or read book Nutrigenomics: How Science Works written by Carsten Carlberg and published by Springer Nature. This book was released on 2020-02-14 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fascinating area of Nutrigenomics describes this daily communication between our diet and our genome. This book describes how nutrition shapes human evolution and demonstrates its consequences for our susceptibility to diseases, such as diabetes and atherosclerosis. Inappropriate diet can yield stress for our cells, tissues and organs and then it is often associated with low-grade chronic inflammation. Overnutrition paired with physical inactivity leads to overweight and obesity and results in increased burden for a body that originally was adapted for a life in the savannahs of East Africa. Therefore, this textbook does not discuss a theoretical topic in science, but it talks about real life and our life-long “chat” with diet. We are all food consumers, thus each of us is concerned by the topic of this book and should be aware of its mechanisms. The purpose of this book is to provide an overview on the principles of nutrigenomics and their relation to health or disease. The content of this book is based on the lecture course “Nutrigenomics”, which is held since 2003 once per year by Prof. Carlberg at the University of Eastern Finland in Kuopio. The book represents an updated but simplified version of our textbook “Nutrigenomics” (ISBN 978-3-319-30413-7). Besides its value as a textbook, “Nutrigenomics: how science works” will be a useful reference for individuals working in biomedicine
Author : Carsten Carlberg
Publisher : Springer
ISBN 13 : 3319304151
Total Pages : 237 pages
Book Rating : 4.3/5 (193 download)
Download or read book Nutrigenomics written by Carsten Carlberg and published by Springer. This book was released on 2016-06-11 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fascinating area of Nutrigenomics describes this daily communication between diet, food and nutrients, their metabolites and our genome. This book describes how nutrition shapes human evolution and demonstrates its consequences for our susceptibility to diseases, such as diabetes and atherosclerosis. Inappropriate diet can yield stress for our cells, tissues and organs and then it is often associated with low-grade chronic inflammation. Overnutrition paired with physical inactivity leads to overweight and obesity and results in increased burden for a body that originally was adapted for a life in the savannas of East Africa. Therefore, this textbook does not discuss a theoretical topic in science, but it talks about real life, and our life-long “chat” with diet. We are all food consumers, thus each of us is concerned by the topic of this book and should be aware of its mechanisms. The purpose of this book is to provide an overview on the principles of nutrigenomics and their relation to health or disease. We are not aiming to compete with more comprehensive textbooks on molecular nutrition, evolutionary biology, genomics, gene regulation or metabolic diseases, but rather will focus on the essentials and will combine, in a compact form, elements from different disciplines. In order to facilitate the latter, we favor a high figure-to-text ratio following the rule “a picture tells more than thousand words”. The content of this book is based on the lecture course “Nutrigenomics”, which is held since 2003 once per year by Prof. Carlberg at the University of Eastern Finland in Kuopio. The book is subdivided into three sections and twelve chapters. Following the "Introduction" there are sections on the "Molecular genetic basis" and the "Links to disease", which take a view on nutrigenomics from the perspective of molecular mechanisms or from the causes of metabolic diseases, respectively. Besides its value as a textbook, Nutrigenomics will be a usefull reference for individuals working in biomedicine.
Author : Jiqiu Wang
Publisher : Frontiers Media SA
ISBN 13 : 2889743411
Total Pages : 160 pages
Book Rating : 4.8/5 (897 download)
Download or read book Anti-obesity: Targeting Brown and Beige Adipocytes written by Jiqiu Wang and published by Frontiers Media SA. This book was released on 2022-02-04 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Joana Vieira Silva
Publisher : Springer Nature
ISBN 13 : 3030444368
Total Pages : 444 pages
Book Rating : 4.0/5 (34 download)
Download or read book Tissue-Specific Cell Signaling written by Joana Vieira Silva and published by Springer Nature. This book was released on 2020-05-29 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Signal transduction comprises the intracellular biochemical signals which induce the appropriate cell response to an external stimulus. The players in signal transduction are diverse, from small molecules as first messengers, to proteins, receptors, transcription factors, among many others. The different signaling pathways and the crosstalk between them originates the unique signaling profile of every cell type in the human body. The cell signaling specificity depends on several aspects including protein composition, subcellular localization and complexes and gene promoters. This textbook provides a comprehensive overview of the specific signaling pathways on a variety of human tissues. This information can be of great value for health science researchers, professionals and students to understand key pathways for tissue-specific functions in the plethora of signals, signals receptors, transducers and effectors. Chapter 3 and 15 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Author : Bruce Spiegelman
Publisher : Springer
ISBN 13 : 3319727907
Total Pages : 108 pages
Book Rating : 4.3/5 (197 download)
Download or read book Hormones, Metabolism and the Benefits of Exercise written by Bruce Spiegelman and published by Springer. This book was released on 2018-03-07 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.
Author : Ashok K. Srivastava
Publisher : Springer Science & Business Media
ISBN 13 : 9780792381136
Total Pages : 206 pages
Book Rating : 4.3/5 (811 download)
Download or read book Insulin Action written by Ashok K. Srivastava and published by Springer Science & Business Media. This book was released on 1998-05-31 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1996 the 75th anniversary of the discovery of insulin was celebrated at the University of Toronto, the scene of that discovery in 1921. This volume was stimulated by the scientific program which was staged at that time and brought together much of the world's best talent to discuss and analyze the most recent developments in our understanding of pancreatic function, insulin secretion, the interaction of insulin with its target tissues, the mechanism of insulin action at the cellular level, and the defects which underlie both Type I (insulin-dependent diabetes mellitus, IDDM) and Type II (noninsulin-dependent diabetes mellitus, NIDDM) forms of the disease. We have chosen to focus the present volume on work related to insulin action.
Author : Shamim I. Ahmad
Publisher : Springer
ISBN 13 : 3319198211
Total Pages : 375 pages
Book Rating : 4.3/5 (191 download)
Download or read book Obesity written by Shamim I. Ahmad and published by Springer. This book was released on 2015-10-19 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings a comprehensive treatise about obesity, examining the measures that can be taken to stop and even reduce obesity if these right measures are taken in time. Recent studies show that obesity is on the increase at an alarming rate, especially in the industrialized and affluent countries. A number of reasons have been put forward for this increase, including life style choices, over-eating, over-use of commercially processed food, addiction for fast food, high caloric diet specially containing high levels of sugar and fat, lack of exercise and sedentary life style. Also genetic make up has been associated with obesity. Obesity can lead to a variety of lethal diseases, notably coronary heart disease, cancer and diabetes. These diseases account for the highest number of human death amongst all other causes. There are also a number of other side effects associated with obesity including increased stress, loss of intelligentsia, pancreatitis, premature birth and osteoarthritis. In recent years media have been playing important roles in highlighting the lethality and damage caused by obesity, nevertheless no significant effects can be seen in the population and obesity remains on the increase, especially amongst children. The editors believe that it is important that more education, campaign and research are used to stop this increasing disease.
Author : Jesmine Khan
Publisher : BoD – Books on Demand
ISBN 13 : 1838801812
Total Pages : 230 pages
Book Rating : 4.8/5 (388 download)
Download or read book Cellular Metabolism and Related Disorders written by Jesmine Khan and published by BoD – Books on Demand. This book was released on 2020-07-15 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with a vital topic: metabolism in the cells of the body and various disorders due to its imbalance and/or diseases that disrupt the metabolism of the body. The objective of this book was to collect and compile up-to-date information from reputed researchers in their respective fields to disseminate the latest information about topics that have profound effects on the metabolic processes in the body including insulin resistance, diabetes mellitus, hypothyroidism, metabolic syndrome, glycogen storage disease, and the urea cycle disorder. In total, there are 12 chapters in this book in which the authors have shared their research findings and real-life experiences in managing their patients.
Author : Michael Freemark
Publisher : Springer Science & Business Media
ISBN 13 : 1603278745
Total Pages : 473 pages
Book Rating : 4.6/5 (32 download)
Download or read book Pediatric Obesity written by Michael Freemark and published by Springer Science & Business Media. This book was released on 2010-09-14 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Childhood obesity and its co-morbidities -- including type 2 diabetes, hypertension, dyslipidemia, sleep apnea, and fatty liver disease -- have seen striking increases in recent years. Despite a wealth of investigation, there is considerable controversy regarding the etiology of childhood obesity and the optimal approaches for prevention and treatment. Pediatric Obesity: Etiology, Pathogenesis, and Treatment addresses the controversy with a range of features that make it a unique resource for those who care for obese children and their families. Written from a perspective that is international in scope, the distinguished authors re-assess the roles of genetic and environmental factors in the pathogenesis of childhood obesity and critically review new studies of the effects of lifestyle, pharmacologic, and surgical interventions. The evidence-based approach of Pediatric Obesity: Etiology, Pathogenesis, and Treatment provides a comprehensive and invaluable guide for all healthcare providers concerned with the evaluation and care of children with nutritional and metabolic disease and with the societal implications of the obesity epidemic.
Author : Takeshi Yoneshiro
Publisher : Frontiers Media SA
ISBN 13 : 2889662829
Total Pages : 187 pages
Book Rating : 4.8/5 (896 download)
Download or read book Current Challenges for Targeting Brown Fat Thermogenesis to Combat Obesity written by Takeshi Yoneshiro and published by Frontiers Media SA. This book was released on 2020-12-28 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author : Jiyoung Bae
Publisher :
ISBN 13 :
Total Pages : 177 pages
Book Rating : 4.:/5 (14 download)
Download or read book Brown and Beige Adipocytes written by Jiyoung Bae and published by . This book was released on 2015 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent findings of brown adipocytes and brown-like or beige adipocytes, capable of dissipating energy as heat, in adult humans have promised new hope for obesity treatment and prevention. Understanding of the regulation of brown and beige adipocytes will provide novel strategies to reach the goal. Pattern recognition receptors (PRR) are responsible for inflammation in adipose tissue, which leads to adipose dysfunction and obesity associated chronic diseases. It has been shown that PRR activation induces inflammation, leading to insulin resistance in white adipocytes and white adipose tissue (WAT). However, the roles of PRR activation in brown adipocytes and brown adipose tissue (BAT) have not been studied. In addition, in vitro and in vivo studies have shown that bioactive food components can contribute to obesity prevention; however, very few bioactive food components have been studied for their beneficial effects in promoting development and function of brown and beige adipocytes. This dissertation reports that (1) mRNA of PRRs and inflammatory cytokines/chemokines are upregulated in the BAT of both diet induced obesity mice model and ob/ob mice model; (2) activation of PRRs induces activation of NF-kB and MAPK signaling pathways, leading to upregulation of the proinflammatory genes, MCP- 1, IL-6, RANTES, and TNF-[alpha], in mature brown adipocytes; (3) activation of PRRs suppresses UCP-1 expression, leading to decreased mitochondrial respiration and thermogenesis in mature brown adipocytes; (4) chronic activation of PRRs reduces adipogenesis and suppresses expression of brown-specific genes in both classic brown adipocytes and multipotent stem cells. This dissertation further demonstrates that naringenin, a flavanone mainly found in citrus fruits, enhances thermogenic activation in isoproterenol-stimulated 3T3-L1 adipocytes through PKA/p38 MAPK pathways. The results suggest that PRR-mediated inflammation in brown adipocytes may be a potential target for regulating BAT development and function for obesity treatment and prevention. Dietary bioactive compounds, such as naringenin, could be beneficial in promoting functional BAT, thereby contributing to energy expenditure.
Author : Lauren Kokai
Publisher : Academic Press
ISBN 13 : 0128193778
Total Pages : 486 pages
Book Rating : 4.1/5 (281 download)
Download or read book Scientific Principles of Adipose Stem Cells written by Lauren Kokai and published by Academic Press. This book was released on 2021-08-19 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Principles of Adipose Stem Cells provides readers with in-depth and expert knowledge on adipose stem cells, their developmental biologic origins, foundational research on ASC signaling mechanisms and immunomodulatory properties, and clinical insights into applications in regenerative medicine. Topics covered include basic adipose stem cell developmental biology and mechanisms of regulating self-renewal and activation in the stem cell niche, important methods for isolation and characterizing ASCs, and data on the impact on human demographics (age, sex, BMI) on ASC phenotype. A section devoted to ASC biology, ASCs for stem cell therapy and regenerative medicine, and ASCs in tissue engineering applications are also included. The book is written for scientists and clinicians who are broadly familiar with stem cells and basic cell biology principles and those seeking advanced information on adipose stem cells. Coverage of basic adipose stem cell developmental biology (maturation process during embryogenesis) and mechanisms of regulating self-renewal and activation in the stem cell niche Includes important methods for isolation and characterizing ASCs, as well as known data any impact of human demographics (age, sex, BMI) on ASC phenotype An entire section dedicated to ASC biology, additional sections will be devoted to ASCs for stem cell therapy and regenerative medicine, as well as ASCs in tissue engineering applications
Author : Todd Leff
Publisher : John Wiley & Sons
ISBN 13 : 9783527629534
Total Pages : 530 pages
Book Rating : 4.6/5 (295 download)
Download or read book Adipose Tissue in Health and Disease written by Todd Leff and published by John Wiley & Sons. This book was released on 2010-03-19 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely and most comprehensive reference available on the topic covers all the different aspects vital in the fight against the global obesity epidemic. Following a look at adipose tissue development and morphology, the authors go on to examine its metabolic and endocrine functions and its role in disease. The final section deals with comparative and evolutionary aspects of the tissue. The result is an essential resource for cell and molecular biologists, physiologists, biochemists, pharmacologists, and those working in the pharmaceutical industry.
Author : Jan Gordeladze
Publisher : BoD – Books on Demand
ISBN 13 : 9535129953
Total Pages : 254 pages
Book Rating : 4.5/5 (351 download)
Download or read book Adiposity written by Jan Gordeladze and published by BoD – Books on Demand. This book was released on 2017-03-15 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first in a series of two, featuring the Adiposity - Epidemiology and Treatment Modalities, serving as a summary of the traditional views on how the organ systems are affected when higher organs start to suffer from enhanced body weight, where most of this additional weight consists of white adipose tissue (WAT). The understanding of the "epidemiology" of obesity will consequently enable clinicians and researchers to better understand the untoward "trends" of "metabolic aberrations" from a well-organized and health-bringing homeostasis, with fully responding WAT and BAT, thus enabling a balance between fat-producing and fat-metabolizing tissues for the benefit of the various organ systems taking care of the fat and carbohydrate metabolism, normally yielding a balanced energy turnover, ensuring "healthy" cell phenotypes, which optimally coordinate the energy metabolism in a well-functioning organism throughout a lifetime.
