Brevetoxins

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Marine and Freshwater Toxins

Author : P. Gopalakrishnakone
Publisher : Springer
ISBN 13 : 9789400764187
Total Pages : 0 pages
Book Rating : 4.7/5 (641 download)

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Book Synopsis Marine and Freshwater Toxins by : P. Gopalakrishnakone

Download or read book Marine and Freshwater Toxins written by P. Gopalakrishnakone and published by Springer. This book was released on 2016-03-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.

Model Synthetic Studies on Brevetoxins

Author : Kai Rossen
Publisher :
ISBN 13 :
Total Pages : 298 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Model Synthetic Studies on Brevetoxins by : Kai Rossen

Download or read book Model Synthetic Studies on Brevetoxins written by Kai Rossen and published by . This book was released on 1987 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Marine Biotoxins

Author : Hans P. Egmond
Publisher : Food & Agriculture Org.
ISBN 13 : 9789251051290
Total Pages : 300 pages
Book Rating : 4.0/5 (512 download)

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Book Synopsis Marine Biotoxins by : Hans P. Egmond

Download or read book Marine Biotoxins written by Hans P. Egmond and published by Food & Agriculture Org.. This book was released on 2004 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This paper provides an extensive review of different aspects of five shellfish-poisoning syndromes (paralytic, diarrhoeic, amnesic, neurologic and azapiracid), as well as one fish-poisoning syndrome (ciguatera fish poisoning), and discusses in detail the causative toxins produced by marine organisms, chemical structures and analytical methods of the toxins, habitat and occurrence of the toxin-producing organisms, case studies and existing regulations. Based on this analysis, risk assessments are carried out for each of the toxins, and recommendations are elaborated to improve the management of these risks in order to reduce the harmful effect of these toxins on public health.

Harmful Algal Blooms

Author : Sandra E. Shumway
Publisher : John Wiley & Sons
ISBN 13 : 1118994655
Total Pages : 696 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Harmful Algal Blooms by : Sandra E. Shumway

Download or read book Harmful Algal Blooms written by Sandra E. Shumway and published by John Wiley & Sons. This book was released on 2018-08-06 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: Harmful Algal Blooms: A Compendium Desk Reference erläutert die Grundlagen der schädlichen Algenblüte (HAB) und bietet die notwendigen technischen Informationen, wenn es um unerwartete oder unbekannte schädliche Ereignisse in Zusammenhang mit Algen geht. Dieses Fachbuch behandelt die Gründe für die schädliche Algenblüte, erfolgreiche Management- und Monitoring-Programme, Kontroll-, Präventions- und Minderungsstrategien, die wirtschaftlichen Folgen, Gesundheitsrisiken sowie die Folgen für die Nahrungskette und Ökosysteme. Darüber hinaus bietet es ausführliche Informationen zu den häufigsten HAB-Arten. Harmful Algal Blooms: A Compendium Desk Reference ist ein unschätzbares Referenzwerk für Manager, Einsteiger in das Fachgebiet, Praktiker mit eingeschränkten Zugang zu wissenschaftlicher Literatur und alle, die schnell Zugriff auf Informationen benötigen, insbesondere vor dem Hintergrund neuartiger oder unerwarteter HAB-Ereignisse. Die drei Herausgeber gehören zu den weltweit führenden Forschern auf dem Fachgebiet. Führende Experten haben ebenfalls zu diesem Fachbuch beigetragen, das sich zu einem wichtigen Referenzwerk des Fachgebiets entwickeln wird, zumal das Thema immer mehr an Bedeutung gewinnt.

Toxins and Biologically Active Compounds from Microalgae, Volume 1

Author : Gian Paolo Rossini
Publisher : CRC Press
ISBN 13 : 148221069X
Total Pages : 542 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Toxins and Biologically Active Compounds from Microalgae, Volume 1 by : Gian Paolo Rossini

Download or read book Toxins and Biologically Active Compounds from Microalgae, Volume 1 written by Gian Paolo Rossini and published by CRC Press. This book was released on 2016-04-19 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a structured account of the existing knowledge of toxic algae, the chemistry of the toxins they produce, the effects these substances exert in humans and wildlife, as well as the strategies envisaged to protect public health and the environment. It covers recent advances in the understanding of the biology of toxin producers and

Brevetoxin

Author : Natalie Thompson
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (816 download)

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Book Synopsis Brevetoxin by : Natalie Thompson

Download or read book Brevetoxin written by Natalie Thompson and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Karenia brevis is the major harmful algal bloom-forming species in the Gulf of Mexico, and produces neurotoxins, known as brevetoxins, that cause large fish kills, neurotoxic shellfish poisoning, and human respiratory distress. Brevetoxins are polyethers that bind voltage-sensitive sodium channels, opening them for prolonged periods of time. Clonal cultures of K. brevis exhibit unique brevetoxin profiles, which not only differ from one another, but also change when subjected to different environmental conditions. The brevetoxin structures were elucidated 30 years ago without any breakthroughs for the biosynthetic pathway. These unique ladder-like polyethers have 10 (PbTx-1) or 11 (PbTx-2) rings, indicating that they are synthesized as secondary metabolites by polyketide synthases. The extensive size of the genome and the lack of histones and nucleosomes combined with the additional regulatory step of a trans-splicing spliced leader sequence make normal molecular techniques ineffective in determining the genes involved in toxin synthesis. The goal of this project is to identify a potential link between toxin, gene, and function. One objective is to take the next step towards identifying the genes associated with the synthesis and regulation of brevetoxins and to help elucidate the hypothesized gene clusters of multi-protein enzymatic complexes involved in brevetoxin production, one for each backbone. The second objective is to make an effort to determine the in vivo function of the costly brevetoxins by identifying possible ion channels, which could be osmotically regulated by the toxins. Genes for polyketide synthases (PKS) were identified in K. brevis, obtained from Expressed Sequence Tag (EST) libraries. In this work, reverse transcription polymerase chain reactions (RT-PCR) were used to generate pools of complementary DNA (cDNA), which was used in real-time quantitative polymerase chain reactions (qPCR) to give relative amounts of PKS transcripts. K. brevis clones have shown a significant increase in toxin production after a rapid shift from high salinity to low salinity, indicating a regulation of brevetoxin synthesis. To gain a better understanding of regulation of toxin production during algal blooms, we compared the toxin levels under different conditions to the transcript levels of PKS genes, as determined by quantitative RT-PCR. In a separate line of investigation, an in silico analysis of the EST library was performed to identify ion channel genes expressed by K. brevis, which may be the in vivo binding site of brevetoxin. The information generated from this project will help to elucidate the effects of environmental variations on toxin production and the biological function of toxin production -- valuable information for the shellfish industries and public health.

Environmental Health Perspectives

Author :
Publisher :
ISBN 13 :
Total Pages : 1490 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Environmental Health Perspectives by :

Download or read book Environmental Health Perspectives written by and published by . This book was released on 2003 with total page 1490 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Medical Toxicology of Natural Substances

Author : Donald G. Barceloux
Publisher : John Wiley & Sons
ISBN 13 : 1118382765
Total Pages : 1196 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Medical Toxicology of Natural Substances by : Donald G. Barceloux

Download or read book Medical Toxicology of Natural Substances written by Donald G. Barceloux and published by John Wiley & Sons. This book was released on 2012-03-07 with total page 1196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest and information in the field of medical toxicology has grown rapidly, but there has never been a concise, authoritative reference focused on the subjects of natural substances, chemical and physical toxins, drugs of abuse, and pharmaceutical overdoses. Medical Toxicology of Natural Substances finally gives you an easily accessible resource for vital toxicological information on foods, plants, and animals in key areas in the natural environment.

Infectious Diseases of Wild Birds

Author : Nancy J. Thomas
Publisher : John Wiley & Sons
ISBN 13 : 0470344369
Total Pages : 496 pages
Book Rating : 4.4/5 (73 download)

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Book Synopsis Infectious Diseases of Wild Birds by : Nancy J. Thomas

Download or read book Infectious Diseases of Wild Birds written by Nancy J. Thomas and published by John Wiley & Sons. This book was released on 2008-01-09 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Free-living birds encounter multiple health hazards brought on by viruses, bacteria, and fungi, some which in turn can significantly impact other animal populations and human health. Newly emerging diseases and new zoonotic forms of older diseases have brought increased global attention to the health of wild bird populations. Recognition and management of these diseases is a high priority for all those involved with wildlife. Infectious Diseases of Wild Birds provides biologists, wildlife managers, wildlife and veterinary health professionals and students with the most comprehensive reference on infectious viral, bacterial and fungal diseases affecting wild birds. Bringing together contributions from an international team of experts, the book offers the most complete information on these diseases, their history, causative agents, significance and population impact. Focusing on more than just treatment, special emphasis is given to disease processes, recognition and epidemiology.

Haschek and Rousseaux's Handbook of Toxicologic Pathology

Author : Wanda M Haschek
Publisher : Academic Press
ISBN 13 : 0124157653
Total Pages : 3055 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Haschek and Rousseaux's Handbook of Toxicologic Pathology by : Wanda M Haschek

Download or read book Haschek and Rousseaux's Handbook of Toxicologic Pathology written by Wanda M Haschek and published by Academic Press. This book was released on 2013-05-01 with total page 3055 pages. Available in PDF, EPUB and Kindle. Book excerpt: Haschek and Rousseaux's Handbook of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. The 3e has been expanded by a full volume, and covers aspects of safety assessment not discussed in the 2e. Completely revised with many new chapters, it remains the most authoritative reference on toxicologic pathology for scientists and researchers studying and making decisions on drugs, biologics, medical devices and other chemicals, including agrochemicals and environmental contaminants. New topics include safety assessment, the drug life cycle, risk assessment, communication and management, carcinogenicity assessment, pharmacology and pharmacokinetics, biomarkers in toxicologic pathology, quality assurance, peer review, agrochemicals, nanotechnology, food and toxicologic pathology, the environment and toxicologic pathology and more. Provides new chapters and in-depth discussion of timely topics in the area of toxicologic pathology and broadens the scope of the audience to include toxicologists and pathologists working in a variety of settings Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology Features hundreds of full color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations

Outstanding Marine Molecules

Author : Stephane La Barre
Publisher : John Wiley & Sons
ISBN 13 : 3527681531
Total Pages : 1009 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Outstanding Marine Molecules by : Stephane La Barre

Download or read book Outstanding Marine Molecules written by Stephane La Barre and published by John Wiley & Sons. This book was released on 2014-03-05 with total page 1009 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using a number of outstanding examples, this text introduces readers to the immense variety of marine natural compounds, the methodologies to characterize them and the approaches to explore their industrial potential. Care is also taken to discuss the function and ecological context of the compounds. Carefully produced and easy to read, this book serves students and professionals wishing to familiarize themselves with the field, and is ideally suited as a course book for both industry to academia.

Methods of Analysis of Food Components and Additives

Author : Semih Otles
Publisher : CRC Press
ISBN 13 : 1439815534
Total Pages : 534 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Methods of Analysis of Food Components and Additives by : Semih Otles

Download or read book Methods of Analysis of Food Components and Additives written by Semih Otles and published by CRC Press. This book was released on 2011-11-16 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: With diet, health, and food safety news making headlines on a regular basis, the ability to separate, identify, and analyze the nutrients, additives, and toxicological compounds found in food and food components is more important than ever. This requires proper training in the application of best methods, as well as efforts to improve existing meth

The Food Safety Hazard Guidebook

Author : Richard Lawley
Publisher : Royal Society of Chemistry
ISBN 13 : 1847558399
Total Pages : 433 pages
Book Rating : 4.8/5 (475 download)

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Book Synopsis The Food Safety Hazard Guidebook by : Richard Lawley

Download or read book The Food Safety Hazard Guidebook written by Richard Lawley and published by Royal Society of Chemistry. This book was released on 2008-06-27 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food safety is important and consumers have a right to expect that those who supply the food that they buy have taken every care to manufacture products that will do them no harm. Those with a responsibility for the regulation of the global food industry recognise this principle and legislate accordingly and the business of managing and regulating the safety of the food supply chain has come a long way in the last 25 years or so. Prompted by the emergence of new food safety hazards, such as the bacterial pathogens Listeria monocytogenes and E. coli O157, powerful new techniques for evaluating and managing the risks presented by these threats have been developed. For example, hazard analysis critical control point, or HACCP, has now become the food safety management system of choice worldwide. Although the food safety management tools are now widely available, they are still virtually useless unless they are supported by adequate and accurate information. HACCP does not work unless its practitioners have access to enough data and scientific knowledge to enable them to understand hazards and how to control them effectively. The Food Safety Hazard Guidebook is an attempt to address the problem of accessing the available information by distilling the key facts about a wide range of individual food safety hazards into a single text. The result is a guidebook, rather than an encyclopaedia, which acts as a portal for the immense and ever expanding body of scientific knowledge that exists for food safety. It is an easy-to-use information resource for anyone with a professional interest in the safety of the food supply. The book is easy to navigate and presents concise and carefully researched factual information on a wide range of biological and chemical hazards in a clear format that is designed to support risk analysis exercises and HACCP studies. It covers a broad range of established and emerging food safety hazards and includes details of authoritative sources of further information (many web-based) for those seeking to examine a topic in greater depth. The section on food allergens is a particularly valuable component of the book, the chapters on fish toxins are also useful and unusual in a book of this kind and bacterial pathogens are comprehensively covered. One of the most important features of the book is the wide scope of the content and the highly structured format designed to help the reader find information quickly. Other key benefits to the reader are: -The wide range of biological and chemical hazards covered in a single book -Written specifically with food industry professionals in mind -Easy to navigate and accessible for the non-expert -Clear and concise presentation of factual information presented in a format that lends itself to use in risk assessment exercises -Inclusion of references and web links to reliable sources of further information on each chapter -specifically designed for practical use by a professional readership

Harmful Algal Blooms

Author : Sandra E. Shumway
Publisher : John Wiley & Sons
ISBN 13 : 111899468X
Total Pages : 959 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Harmful Algal Blooms by : Sandra E. Shumway

Download or read book Harmful Algal Blooms written by Sandra E. Shumway and published by John Wiley & Sons. This book was released on 2018-05-21 with total page 959 pages. Available in PDF, EPUB and Kindle. Book excerpt: Harmful Algal Blooms: A Compendium Desk Reference erläutert die Grundlagen der schädlichen Algenblüte (HAB) und bietet die notwendigen technischen Informationen, wenn es um unerwartete oder unbekannte schädliche Ereignisse in Zusammenhang mit Algen geht. Dieses Fachbuch behandelt die Gründe für die schädliche Algenblüte, erfolgreiche Management- und Monitoring-Programme, Kontroll-, Präventions- und Minderungsstrategien, die wirtschaftlichen Folgen, Gesundheitsrisiken sowie die Folgen für die Nahrungskette und Ökosysteme. Darüber hinaus bietet es ausführliche Informationen zu den häufigsten HAB-Arten. Harmful Algal Blooms: A Compendium Desk Reference ist ein unschätzbares Referenzwerk für Manager, Einsteiger in das Fachgebiet, Praktiker mit eingeschränkten Zugang zu wissenschaftlicher Literatur und alle, die schnell Zugriff auf Informationen benötigen, insbesondere vor dem Hintergrund neuartiger oder unerwarteter HAB-Ereignisse. Die drei Herausgeber gehören zu den weltweit führenden Forschern auf dem Fachgebiet. Führende Experten haben ebenfalls zu diesem Fachbuch beigetragen, das sich zu einem wichtigen Referenzwerk des Fachgebiets entwickeln wird, zumal das Thema immer mehr an Bedeutung gewinnt.

Seafood and Freshwater Toxins

Author : Luis M. Botana
Publisher : CRC Press
ISBN 13 : 146650515X
Total Pages : 1215 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Seafood and Freshwater Toxins by : Luis M. Botana

Download or read book Seafood and Freshwater Toxins written by Luis M. Botana and published by CRC Press. This book was released on 2014-03-12 with total page 1215 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last few years have brought about many changes in the field of marine and freshwater toxins, with advances in analytical technology and the realization that these toxins are a global issue. Offering a complete reference guide, Seafood and Freshwater Toxins: Pharmacology, Physiology, and Detection, Third Edition addresses all aspects of the soci

Phycotoxins

Author : Luis M. Botana
Publisher : John Wiley & Sons
ISBN 13 : 1118500334
Total Pages : 545 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Phycotoxins by : Luis M. Botana

Download or read book Phycotoxins written by Luis M. Botana and published by John Wiley & Sons. This book was released on 2015-03-30 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phycotoxins are a diverse group of poisonous substances produced by certain seaweed and algae in marine and fresh waters and are important to the scientific community for many reasons, the most obvious being that they pose food safety issues which requires a large investment to regularly monitor the presence of these compounds in foods. Phycotoxins: Chemistry and Biochemistry, second edition presents the most updated information available on phycotoxins. Major emphases are given to chemistry and biochemistry, while origins, mechanism of action, toxicology, and analytical methodology are also covered. Since the publication of the first edition, there have been major advances in the science of marine and aquatic toxins, as well as advances in toxicology, analytical chemistry and pharmacology. This fully revised and updated edition includes several new chapters, including those on ciguatoxins, pinnatoxin, ichthyotoxins, as well as new chapters on food safety control of marine toxins, climate change and water toxins, and microalgae as a source of nutraceuticals. The book will be of interest to toxicologists, marine, food, and plant scientists, as well as researchers and academics in the areas of food science, medicine, public health, toxicology, pharmacology and marine biology.

Marine Toxins as Research Tools

Author : Nobuhiro Fusetani
Publisher : Springer Science & Business Media
ISBN 13 : 3540878955
Total Pages : 268 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Marine Toxins as Research Tools by : Nobuhiro Fusetani

Download or read book Marine Toxins as Research Tools written by Nobuhiro Fusetani and published by Springer Science & Business Media. This book was released on 2009-01-31 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Marine organisms produce a wide array of toxins, many of which are not only structurally unusual, but also show potent and interesting modes of action. Since the discovery of tetrodotoxin, a pufferfish toxin, as a potent and selective blocker of Na+ channels in 1964, it has been widely used as a research tool in pharmacological and physiological research. This has led to the identification of a number of important biological functions for Na+ channels. In recent years, much biological research has been carried out at molecular and cellular levels, and therefore selective inhibitors of enzymes and selective antagonist/agonists of receptors and channels have become increasingly important research tools. Accordingly, interest in using such compounds as reagents has increased. Marine toxins are some of the most popular research tools and have already contributed much to our understanding of biological processes and disease mechanisms.