Breast Cancer Treatment By Focused Microwave Thermotherapy

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Breast Cancer Treatment by Focused Microwave Thermotherapy

Author : Alan Jeffrey Fenn
Publisher : Jones & Bartlett Learning
ISBN 13 : 9780763748708
Total Pages : 244 pages
Book Rating : 4.7/5 (487 download)

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Book Synopsis Breast Cancer Treatment by Focused Microwave Thermotherapy by : Alan Jeffrey Fenn

Download or read book Breast Cancer Treatment by Focused Microwave Thermotherapy written by Alan Jeffrey Fenn and published by Jones & Bartlett Learning. This book was released on 2007 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast Cancer Treatment By Focused Microwave Thermotherapy Provides A Comprehensive Overview Of The Technology And Application Of Microwave Thermography, A Cutting-Edge, Non-Invasive Therapy For Treating Breast Tumors. Chapter Topics Include Thermotherapy For Invasive Breast Cancer, Microwave Thermotherapy For Breast Cancer And Other Breast Lesions, Adaptive Focused Microwave Phased Array Thermotherapy System And Method For Treating The Intact Breast, Focused Microwave Radiation Theory And Analysis, Preclinical Results For Focused Microwave Phased Array Thermotherapy For Treating The Intact Breast, Phase I Safety Study For Focused Microwave Thermotherapy For Invasive Carcinomas In Patients Scheduled For Mastectomy, Phase II Thermal Dose Escalation Study For Early-State Breast Carcinomas In Patients Scheduled For Breast Conservation Surgery, Randomized Study Of Focused Microwave Thermotherapy For Early-Stage Breast Carcinomas In Patients Scheduled For Breast Conservation Surgery: Thermotherapy Prior To Surgery Compared To Surgery Alone, Randomized Study Of Preoperative Focused Microwave Thermotherapy In Combination With Preoperative Anthracycline-Based Chemotherapy For Patients With Large Breast Carcinomas: Preoperative Thermotherapy Compared To Preoperative Chemotherapy Alone To Breast Cancer, And Future Clinical Research Areas For Focused Microwave Breast Thermotherapy.

Adaptive Phased Array Thermotherapy for Cancer

Author : Alan Jeffrey Fenn
Publisher : Artech House
ISBN 13 : 1596933801
Total Pages : 241 pages
Book Rating : 4.5/5 (969 download)

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Book Synopsis Adaptive Phased Array Thermotherapy for Cancer by : Alan Jeffrey Fenn

Download or read book Adaptive Phased Array Thermotherapy for Cancer written by Alan Jeffrey Fenn and published by Artech House. This book was released on 2009 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: From electromagnetic field theory for tissue heating... to simulations of adaptive phased array thermotherapy for deep tumors of the torso... to coverage of arrays for tumors in the head, neck, breast, and chest wall, this timely resource offers you expert guidance in this emerging area.

Non-surgical Ablation Therapy for Early-stage Breast Cancer

Author : Takayuki Kinoshita
Publisher : Springer
ISBN 13 : 4431544631
Total Pages : 220 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Non-surgical Ablation Therapy for Early-stage Breast Cancer by : Takayuki Kinoshita

Download or read book Non-surgical Ablation Therapy for Early-stage Breast Cancer written by Takayuki Kinoshita and published by Springer. This book was released on 2016-06-21 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering the history of breast cancer, theory of radiofrequency ablation (RFA), resection of carcinoma, imaging before and after non-surgical ablation therapy and quality of life, this book focuses on extensive breast-conserving treatment for the preservation of a cosmetically acceptable breast. It investigates the feasibility of percutaneous, minimally invasive techniques to ablate breast tumors and several modalities such as cryosurgery, laser ablation, thermoablation and high-intensity focused ultrasound. Non-surgical Ablation Therapy for Early-stage Breast Cancer centers on RFA and provides insights into cryoablation and focused ultrasound surgery. RFA has been shown to be effective for treating tumors in many types of tissue, including liver, bone, brain, kidney, pancreas and prostate. As such this book is a valuable resource for breast and general surgeons, radiation oncologists and medical oncologists in all areas. The extensive discussions enable scholars to gain radiological expertise and a basic understanding of molecular biology, leading to better surgery without scalpels.

A Novel Combination of Thermal Ablation and Heat-Inducible Gene Therapy for Breast Cancer Treatment

Author :
Publisher :
ISBN 13 :
Total Pages : 6 pages
Book Rating : 4.:/5 (495 download)

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Book Synopsis A Novel Combination of Thermal Ablation and Heat-Inducible Gene Therapy for Breast Cancer Treatment by :

Download or read book A Novel Combination of Thermal Ablation and Heat-Inducible Gene Therapy for Breast Cancer Treatment written by and published by . This book was released on 2008 with total page 6 pages. Available in PDF, EPUB and Kindle. Book excerpt: High intensity focused ultrasound (HIFU) is a rapidly developing technique for cancer thermal ablation with secondary biological effects, such as heat shock response, that may be harnessed for adjunct therapies. To gain further insight into the potential for HIFU to be utilized in conjunction with gene therapy, a transparent cell-embedded tissue mimicking phantom was developed. Most physical parameters of the agrose-based hydrogel fell within the accepted range of values for soft tissues. Lesions produced under different combinations of HIFU intensity and exposure duration could be visualized inside the phantoms. GFP positive cells were primarily found within a circumferential region surrounding the primary site of lesion formation. The thermal necrosis boundary (EM43=240min) fell into this gene activation zone.

Utilization of Micron and Nano Ferrous Particles for Breast Cancer Therapy

Author : Jigar Patel
Publisher :
ISBN 13 :
Total Pages : 368 pages
Book Rating : 4.:/5 (846 download)

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Book Synopsis Utilization of Micron and Nano Ferrous Particles for Breast Cancer Therapy by : Jigar Patel

Download or read book Utilization of Micron and Nano Ferrous Particles for Breast Cancer Therapy written by Jigar Patel and published by . This book was released on 2012 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent study by WHO reported that the incidence rates of cancer are expected to grow by 75% in the year 2030, with breast cancer being one of the seven most commonly occurring cancers. Traditional methods of cancer treatment lead to killing of the tumor cells along with immune effector cells. This research investigated the use of ferrous particles for three novel breast cancer therapies. Studies by the collaborating research group have shown that injection of micron sized iron particles into 4T1 cancer cells implanted on BALB/c mice subjected to a static magnetic field resulted in internal damage and showed some evidence of reduced metastases. Numerical models were developed to estimate the physical damage caused in the tumor due to particle dynamics in both in vivo and in vitro experiments. These models were in agreement with the in vitro trials when the particles were suspended in an elastic medium. Comparisons with the in vivo models require nonlinear tumor properties which are, as of yet, still not available in literature. The other two treatments focused on inducing hyperthermia through alternating magnetic fields (AMF) and continuous wave (CW) lasers, hypothesizing that coupling the hyperthermia and physical damage treatments may enhance the treatment. Hyperthermia (42-46 °C) is thought to alter the function of many structural and enzymatic proteins within the tumor cells, and significantly alter their growth. AMF hyperthermia was investigated using FeCo nanoparticles (27 nm) and temperatures ranging from hyperthermia to thermal ablation levels were observed. Strong magnetic nanoparticles, such as FeCo, were shown to generate higher heat than iron-oxides, whose heating characteristics were calculated using magnetization dynamics through the Stoner-Wohlfarth model and Landau-Lifshitz-Gilbert equation. Numerical simulations differ from the experimental data, so correction factors are discussed alongside optimization parameters to increase the heating rate inside the tumor. Micron particles showed no temperature increase in the presence of an AMF. Lasers in the near infrared range show the deepest penetration into tissues, and for an 820 nm laser, the penetration depth was calculated to be on the order of few millimeters. The absorption efficiency of the micron sized iron particles was smaller than the gold-silica nanoshells used in literature; however, the iron particles were able to generate temperatures desirable for hyperthermia. These three therapies may provide a better alternative to chemotherapy or surgery by slowing the tumor growth, inhibition of untreated contralateral tumor with synergistic effects, and inhibition of metastasis to other organs.

A System Design Specification for Breast Cancer Treatment Using Microwave Hyperthermia

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (934 download)

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Book Synopsis A System Design Specification for Breast Cancer Treatment Using Microwave Hyperthermia by :

Download or read book A System Design Specification for Breast Cancer Treatment Using Microwave Hyperthermia written by and published by . This book was released on 1988* with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Image-guided Focused Ultrasound Therapy

Author : Feng Wu
Publisher : CRC Press
ISBN 13 : 1498711367
Total Pages : 503 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Image-guided Focused Ultrasound Therapy by : Feng Wu

Download or read book Image-guided Focused Ultrasound Therapy written by Feng Wu and published by CRC Press. This book was released on 2024-07-31 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultrasound has been widely used in diagnostic imaging for a long time. In the past 10 years, image-guided focused ultrasound therapy has seen rapid growth, in biomedical science and engineering, and in clinical medicine. The purpose of this book is to bring internationally renowned authorities and experts in this field together to provide up-to-date and comprehensive reviews of basic physics, biomedical engineering, and clinical applications of focused ultrasound therapy in a widely accessible fashion. Focusing on applications in cancer treatment, this book covers basic principles, practical aspects, and clinical applications of focused ultrasound therapy. It reviews the medical physics and bio-effects of focused ultrasound beams on living tissues, dosimetric methods and measurements, transducer engineering, image guidance and monitoring (including magnetic resonance imaging -- MRI -- and ultrasound), treatment delivery systems, and clinical applications. The book also gives practical guidelines on patient setup, target localisation, treatment planning and image-guided procedures for the treatment in various sites, including the prostate, liver, pancreas, breast, kidney, uterus, bone, and brain. The book discusses major challenges for the use of focused ultrasound energy on living tissues and explores the cellular and physiological responses that can be employed in the fight against cancer from biological, physics and engineering perspectives. It also highlights recent advances, including the treatment of solid tumours using image-guided drug delivery, and the exploitation of microbubbles, nanoparticles, and other cutting-edge techniques. Readers who are interested in learning more about the technique and the clinical applications described in each chapter can find more information in the comprehensive bibliographies provided. This book is suitable for anyone involved in, or looking to become involved in, the research and clinical applications of focused ultrasound therapy, including medical professionals, physicists, biomedical engineers, graduate students and others working in this multidisciplinary field. It offers a balanced and critical assessment of state-of-the-art technologies, major challenges, and an outlook on the future of focused ultrasound therapy. It presents a thorough introduction for those new to the field while providing helpful, up-to-date information and guidelines for readers already using this therapy in clinical and pre-clinical settings. Key Features: Brings together a wide range of world-leading experts in this new field, presenting the latest clinical outcomes of using focused ultrasound for the treatment of benign and malignant diseases Covers the fundamental physics of focused ultrasound therapy and ultrasound-mediated drug delivery, including chapters on the mechanism of sonoporation, microbubble and ultrasound interaction, and their potential clinical applications Introduces clinical guidelines for focused ultrasound therapy, including indications and contraindications, treatment goals, the selection of patients, clinical observation during treatment procedure and follow-up, and characteristics of image changes after treatment

The Breast E-Book

Author : Kirby I. Bland
Publisher : Elsevier Health Sciences
ISBN 13 : 0323511872
Total Pages : 1280 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis The Breast E-Book by : Kirby I. Bland

Download or read book The Breast E-Book written by Kirby I. Bland and published by Elsevier Health Sciences. This book was released on 2017-06-29 with total page 1280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in a single, convenient volume, The Breast: Comprehensive Management of Benign and Malignant Diseases, 5th Edition covers every clinically relevant aspect of the field: cancer, congenital abnormalities, hormones, reconstruction, anatomy and physiology, benign breast disease, and more. Building upon the strengths of previous editions, this updated volume by Drs. Kirby I. Bland, Edward M. Copeland III, V. Suzanne Klimberg, and William J Gradishar, includes the latest innovations in breast cancer detection and treatment in a practical, easy-to-use format ideal for today’s surgeons. Delivers step-by-step clinical guidance highlighted by superb illustrations that depict relevant anatomy and pathology, as well as medical and surgical procedures. Reflects the collaborative nature of diagnosis and treatment among radiologists, pathologists, surgeons, oncologists, and other health care professionals who contribute to the management of patients with breast disease. Offers the most comprehensive, up-to-date information on the diagnosis and management of, and rehabilitation following, surgery for benign and malignant diseases of the breast. Covers the latest developments in receptor modulation, targeted monoclonal antibodies, evolving inhibitors with triple-negative disease, and more. Discusses recent minimally invasive surgical techniques and new developments in oncoplastic breast conservation techniques. Contains significant updates to the "Management of Systemic Disease" section that reflect the latest advances in chemotherapy, hormonal resistance, and therapy.

Issues in Cancer Treatment and Therapy: 2011 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464967296
Total Pages : 306 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Issues in Cancer Treatment and Therapy: 2011 Edition by :

Download or read book Issues in Cancer Treatment and Therapy: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Cancer Treatment and Therapy / 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Cancer Treatment and Therapy in a concise format. The editors have built Issues in Cancer Treatment and Therapy: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cancer Treatment and Therapy in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Cancer Treatment and Therapy: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Interventional Radiology Techniques in Ablation

Author : Timothy Clark
Publisher : Springer Science & Business Media
ISBN 13 : 0857290940
Total Pages : 192 pages
Book Rating : 4.8/5 (572 download)

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Book Synopsis Interventional Radiology Techniques in Ablation by : Timothy Clark

Download or read book Interventional Radiology Techniques in Ablation written by Timothy Clark and published by Springer Science & Business Media. This book was released on 2012-10-11 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Techniques in Interventional Radiology series of handbooks describes in detail the various interventional radiology procedures and therapies that are in current practice. The series comprises a number of titles, which cover procedures in angioplasty and stenting, transcatheter embolization and therapy, biopsy and drainage, ablation, pediatric interventional radiology and neurointerventional radiology. Each book is laid out in bullet point format, so that the desired information can be located quickly and easily. Interventional radiologists at all stages, from trainees through to specialists, will find this book a valuable asset for their practice. Interventional Radiology Techniques in Ablation is a practical and concise guide to contemporary techniques in image-guided tumor ablation. This handbook is intended to serve as a quick reference for physicians in interventional radiology training as well as a resource for IR technologists, nurses, nurse practitioners and physician assistants.

Current Surgical Therapy E-Book

Author : John L. Cameron
Publisher : Elsevier Health Sciences
ISBN 13 : 0323461174
Total Pages : 1707 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Current Surgical Therapy E-Book by : John L. Cameron

Download or read book Current Surgical Therapy E-Book written by John L. Cameron and published by Elsevier Health Sciences. This book was released on 2016-11-29 with total page 1707 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than 30 years, Current Surgical Therapy has been the go-to resource for both residents and practitioners for expert advice on today’s best treatment and management options for general surgery. The 12th Edition, by Drs. John L. Cameron and Andrew M. Cameron, remains the ideal reference for written, oral, and recertifying board study, as well as for everyday clinical practice. Twelve brand-new chapters and many new contributing authors keep you up to date with recent changes in this fast-moving field, helping you achieve better outcomes and ensure faster recovery times for your patients. Presents practical, hands-on advice on selecting and implementing the latest surgical approaches from today’s preeminent general surgeons. Approaches each topic using the same easy-to-follow format: disease presentation, pathophysiology, and diagnostics, followed by surgical therapy. Discusses which approach to take, how to avoid or minimize complications, and what outcomes to expect. Helps you visualize how to proceed with full color images throughout. Trusted by generations of general surgeons as the definitive source on the most current surgical approaches, providing a quick, efficient review prior to surgery and when preparing for surgical boards and ABSITEs. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Features nearly 300 succinct, well-illustrated chapters that summarize today’s best treatment and management advice for a wide variety of diseases and associated surgeries. Includes twelve brand-new chapters covering islet allotransplantation; lower extremity amputations; prehospital management of the trauma patient; ERAS: colon surgery; minimally invasive pancreatic surgery; five new chapters on the breast, and more.

Microwave Ablation Treatment of Solid Tumors

Author : Ping Liang
Publisher : Springer
ISBN 13 : 9401793158
Total Pages : 333 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Microwave Ablation Treatment of Solid Tumors by : Ping Liang

Download or read book Microwave Ablation Treatment of Solid Tumors written by Ping Liang and published by Springer. This book was released on 2014-11-17 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microwave ablation is a simple, affordable, and highly precise technique. After its successful application in treating liver tumors, it is now widely used to combat renal tumors, adrenal tumors, thyroid nodes, uterine fibroids and other solid tumors. This book presents 40 successful cases of treating these diseases. A series of picture before treatment, after treatment and from different angles is provided for each kind of tumor treatment. In each chapter, step by step operative techniques and illustrations are included. This book also examines CT, NMR and ultrasonography to evaluate the effect of microwave ablation. Editor Ping Liang, is the Director and Professor at Dept. of Interventional Ultrasound, General Hospital of PLA, Beijing, China. Editor Xiaoling Yu is Professor and Chief physician, Editor Jie Yu is Associate Chief physician at the same department.

Regional Cancer Therapy

Author : Peter M. Schlag
Publisher : Springer Science & Business Media
ISBN 13 : 1597452254
Total Pages : 455 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Regional Cancer Therapy by : Peter M. Schlag

Download or read book Regional Cancer Therapy written by Peter M. Schlag and published by Springer Science & Business Media. This book was released on 2007-10-20 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a biological and pharmacological background for regional cancer therapy, strategies and techniques for regional therapies, and specific indications and results for different tumor entities. Clinical trial concepts and detailed treatment protocols are also presented. This book is essential reading for researchers and clinicians engaged in seeking advanced therapeutic options for cancer patients worldwide.

Current Surgical Therapy E-Book

Author : John L. Cameron
Publisher : Elsevier Health Sciences
ISBN 13 : 0323640605
Total Pages : 1744 pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Current Surgical Therapy E-Book by : John L. Cameron

Download or read book Current Surgical Therapy E-Book written by John L. Cameron and published by Elsevier Health Sciences. This book was released on 2019-10-29 with total page 1744 pages. Available in PDF, EPUB and Kindle. Book excerpt: An ideal resource for written, oral, and recertifying board study, as well as an excellent reference for everyday clinical practice, Current Surgical Therapy, 13th Edition, provides trusted, authoritative advice on today's best treatment and management options for general surgery. Residents and practitioners alike appreciate the consistent, highly formatted approach to each topic, as well as the practical, hands-on advice on selecting and implementing current surgical approaches from today’s preeminent general surgeons. Provides thoroughly updated information throughout all 263 chapters, including focused revisions to the most in-demand topics such as management of rectal cancer, inguinal hernia, and colon cancer. Presents each topic using the same easy-to-follow format: disease presentation, pathophysiology, diagnostics, and surgical therapy. Includes seven all-new chapters: REBOA in Resuscitation of the Trauma Patient, Treatment of Varicose Veins, Management of Infected Grafts, Radiation for Pancreatic Malignancies, Pneumatosis Intestinalis, Proper Use of Cholecystostomy Tubes, and Pelvic Fractures. Integrates all minimally invasive surgical techniques into relevant chapters where they are now standard management. Discusses which approach to take, how to avoid or minimize complications, and what outcomes to expect. Features full-color images throughout, helping you visualize key steps in each procedure. Helps you achieve better outcomes and ensure faster recovery times for your patients. Provides a quick, efficient review prior to surgery and when preparing for surgical boards and ABSITEs.

Breast Cancer Treatment

Author : Nima Rezaei
Publisher : Springer Nature
ISBN 13 : 3031658272
Total Pages : 446 pages
Book Rating : 4.0/5 (316 download)

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Book Synopsis Breast Cancer Treatment by : Nima Rezaei

Download or read book Breast Cancer Treatment written by Nima Rezaei and published by Springer Nature. This book was released on 2024 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are different types of treatment for breast cancer, including surgery, chemotherapy, radiotherapy, hormone therapy, immunotherapy, and targeted therapy. Deciding on the types of treatment depends on several factors, such as the stage and grade of cancer, biomarkers, and general health of patients. The seventh volume of the "Interdisciplinary Cancer Research" series, entitled "Breast Cancer Treatment: An Interdisciplinary Approach" publishes comprehensive reviews on different treatment opportunities on breast cancer. An update on treatment of triple-negative breast cancer and ductal carcinoma in situ is provided. Ablative breast cancer surgery, radiotherapy, and percutaneous breast cancer treatment are explained. Promising hormone immunotherapy combination as well as targeted therapies for breast cancer is also discussed. This interdisciplinary series is of special value to researchers working on oncology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value to researchers and oncologists who wish to extend their knowledge on breast cancer treatment.

Breast Cancer

Author : Umberto Veronesi
Publisher : Springer
ISBN 13 : 3319488481
Total Pages : 892 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Breast Cancer by : Umberto Veronesi

Download or read book Breast Cancer written by Umberto Veronesi and published by Springer. This book was released on 2017-11-03 with total page 892 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with up-to-date information on important advances in the understanding of breast cancer and innovative approaches to its management. Current and emerging perspectives on genetics, biology, and prevention are first discussed in depth, and individual sections are then devoted to pathology, imaging, oncological surgery, plastic and reconstructive surgery, medical oncology, and radiotherapy. In each case the focus is on the most recent progress and/or state of the art therapies and techniques. Further topics to receive detailed consideration include particular conditions requiring multidisciplinary approaches, the investigation of new drugs and immunological agents, lifestyle and psychological aspects, and biostatistics and informatics. The book will be an excellent reference for practitioners, interns and residents in medical oncology, oncologic surgery, radiotherapy, pathology, and human genetics, researchers, and advanced medical students.

Breast Surgery

Author : W. G. Cance
Publisher : IOS Press
ISBN 13 : 9781586031596
Total Pages : 168 pages
Book Rating : 4.0/5 (315 download)

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Book Synopsis Breast Surgery by : W. G. Cance

Download or read book Breast Surgery written by W. G. Cance and published by IOS Press. This book was released on 2001 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volume provides a comprehensive review of the surgical aspects of breast disease from the leaders in their fields. Each chapter offers a discussion of a certain topic or field along with the author's assessment of future directions. The topics range from the surgical management of high risk patients, a well as patients with DCIS and invasive cancer. Chapters include the status of sential lymphadenectomy as well as managment of locally advanced breast cancer, with other topics studying breast surgical training, definition of optimal biopsy methodology, breast reconstruction, chemoprevention, as well as complications of breast surgery and medical/legal issues in breast cancer. This should provide readers with a state-of-the-art discussion of the major surgical issues related to breast disease.