Brain Networks in Aging: Reorganization and Modulation by Interventions

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Publisher : Frontiers Media SA
ISBN 13 : 2889454169
Total Pages : 170 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Brain Networks in Aging: Reorganization and Modulation by Interventions by : Junfeng Sun

Download or read book Brain Networks in Aging: Reorganization and Modulation by Interventions written by Junfeng Sun and published by Frontiers Media SA. This book was released on 2018-02-22 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Old adults undertake multiple reduced cognitive abilities in aging, which are accompanied with specific brain reorganization in forms of regional brain activity and brain tissues, inter-region connectivity, and topology of whole brain networks in both function and structure. The plasticity changes of brain activities in old adults are explained by the mechanisms of compensation and dedifferentiation. For example, older adults have been observed to have greater, usually bilateral, prefrontal activities during memory tasks compared to the typical unilateral prefrontal activities in younger adults, which was explained as a compensation for the reduced brain activities in visual processing cortices. Dedifferentiation is another mechanism to explain that old adults are with much less selective and less distinct activity in task-relevant brain regions compared with younger adults. A larger number of studies have examined the plasticity changes of brain from the perspective of regional brain activities. However, studies on only regional brain activities cannot fully elucidate the neural mechanisms of reduced cognitive abilities in aging, as multiple regions are integrated together to achieve advanced cognitive function in human brain. In recent years, brain connectivity/network, which targets how brain regions are integrated, have drawn increasing attention in neuroscience with the development of neuroimaging techniques and graph theoretical analysis. Connectivity quantifies functional association or neural fibers between two regions that may be spatially far separated, and graph theoretical analysis of brain network examines the complex interactions among multiple regions from the perspective of topology. Studies showed that compared to younger adults, older adults had altered strength of task-relevant functional connectivity between specific brain regions in cognitive tasks, and the alternation of connectivity are correlated to behavior performance. For example, older adults had weaker functional connectivity between the premotor cortex and a region in the left dorsolateral prefrontal cortex in a working memory task. Interventions like cognitive training and neuro-modulation (e.g., transcranial magnetic stimulation) have been shown to be promising in regaining or retaining the decreasing cognitive abilities in aging. However, only few neuroimaging studies have examined the influence of interventions to old adult’s brain activity, connectivity, and cognitive performance. This Research Topic calls for contributions on brain network of subjects in normal aging or with age-related diseases like mild cognitive impairment and Alzheimer’s disease. The studies are expected to be based on neuroimaging techniques including but not limited to functional magnetic resonance imaging, Electroencephalography, and diffusion tensor imaging, and contributions on the influence of interventions to brain networks in aging are highly encouraged. All these studies would enrich our understanding of neural mechanisms underlying aging, and offer new insights for developing possible interventions to retain cognitive abilities in aging subjects.

Brain Networks in Aging: Reorganization and Modulation by Interventions

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Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

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Book Synopsis Brain Networks in Aging: Reorganization and Modulation by Interventions by :

Download or read book Brain Networks in Aging: Reorganization and Modulation by Interventions written by and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Old adults undertake multiple reduced cognitive abilities in aging, which are accompanied with specific brain reorganization in forms of regional brain activity and brain tissues, inter-region connectivity, and topology of whole brain networks in both function and structure. The plasticity changes of brain activities in old adults are explained by the mechanisms of compensation and dedifferentiation. For example, older adults have been observed to have greater, usually bilateral, prefrontal activities during memory tasks compared to the typical unilateral prefrontal activities in younger adults, which was explained as a compensation for the reduced brain activities in visual processing cortices. Dedifferentiation is another mechanism to explain that old adults are with much less selective and less distinct activity in task-relevant brain regions compared with younger adults. A larger number of studies have examined the plasticity changes of brain from the perspective of regional brain activities. However, studies on only regional brain activities cannot fully elucidate the neural mechanisms of reduced cognitive abilities in aging, as multiple regions are integrated together to achieve advanced cognitive function in human brain. In recent years, brain connectivity/network, which targets how brain regions are integrated, have drawn increasing attention in neuroscience with the development of neuroimaging techniques and graph theoretical analysis. Connectivity quantifies functional association or neural fibers between two regions that may be spatially far separated, and graph theoretical analysis of brain network examines the complex interactions among multiple regions from the perspective of topology. Studies showed that compared to younger adults, older adults had altered strength of task-relevant functional connectivity between specific brain regions in cognitive tasks, and the alternation of connectivity are correlated to behavior performance. For example, older adults had weaker functional connectivity between the premotor cortex and a region in the left dorsolateral prefrontal cortex in a working memory task. Interventions like cognitive training and neuro-modulation (e.g., transcranial magnetic stimulation) have been shown to be promising in regaining or retaining the decreasing cognitive abilities in aging. However, only few neuroimaging studies have examined the influence of interventions to old adult's brain activity, connectivity, and cognitive performance. This Research Topic calls for contributions on brain network of subjects in normal aging or with age-related diseases like mild cognitive impairment and Alzheimer's disease. The studies are expected to be based on neuroimaging techniques including but not limited to functional magnetic resonance imaging, Electroencephalography, and diffusion tensor imaging, and contributions on the influence of interventions to brain networks in aging are highly encouraged. All these studies would enrich our understanding of neural mechanisms underlying aging, and offer new insights for developing possible interventions to retain cognitive abilities in aging subjects.

Cognitive and Brain Aging: Interventions to Promote Well-Being in Old Age. Roadmap for Interventions Preventing Cognitive Aging

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

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Book Synopsis Cognitive and Brain Aging: Interventions to Promote Well-Being in Old Age. Roadmap for Interventions Preventing Cognitive Aging by : Pamela M. Greenwood

Download or read book Cognitive and Brain Aging: Interventions to Promote Well-Being in Old Age. Roadmap for Interventions Preventing Cognitive Aging written by Pamela M. Greenwood and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of cognitive aging has evolved from a focus on cataloging age-related declines of brain and mind in healthy older people to a focus on interventions aimed at limiting those declines. Intervention research has obtained convincing evidence of the cognitive benefits of aerobic exercise and working memory training. Recently interest has broadened to include interventions that consider the social and physical environment of the aged individual. Examples of this are investigations of training cognitive-motor integration, interventions to reduce loneliness, mindfulness training, and human factors-based approaches to cognitive deficits. Such approaches move beyond targeting specific abilities in isolation to consider more broadly the overall well-being of the healthy older person. In this Research Topic we call for both empirical and review papers that consider interventions aimed at reducing cognitive and brain aging but also approaches that consider older individuals (animal and human) in their physical and social environment.

The Cambridge Handbook of Successful Aging

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Publisher : Cambridge University Press
ISBN 13 : 1108641431
Total Pages : 969 pages
Book Rating : 4.1/5 (86 download)

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Book Synopsis The Cambridge Handbook of Successful Aging by : Rocío Fernández-Ballesteros

Download or read book The Cambridge Handbook of Successful Aging written by Rocío Fernández-Ballesteros and published by Cambridge University Press. This book was released on 2019-01-24 with total page 969 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies show that more people than ever before are reaching old age in better health and enjoying that health for a longer time. This Handbook outlines the latest discoveries in the study of aging from bio-medicine, psychology, and socio-demography. It treats the study of aging as a multidisciplinary scientific subject, since it requires the interplay of broad disciplines, while offering high motivation, positive attitudes, and behaviors for aging well, and lifestyle changes that will help people to stay healthier across life span and in old age. Written by leading scholars from various academic disciplines, the chapters delve into the most topical aspects of aging today - including biological mechanisms of aging, aging with health, active and productive aging, aging with satisfaction, aging with respect, and aging with dignity. Aimed at health professionals as well as general readers, this Cambridge Handbook offers a new, positive approach to later life.

Cognitive Changes and the Aging Brain

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Publisher : Cambridge University Press
ISBN 13 : 1108688497
Total Pages : pages
Book Rating : 4.1/5 (86 download)

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Book Synopsis Cognitive Changes and the Aging Brain by : Kenneth M. Heilman

Download or read book Cognitive Changes and the Aging Brain written by Kenneth M. Heilman and published by Cambridge University Press. This book was released on 2019-12-05 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the changes in the brain and in cognitive functions that occur with aging in the absence of a neurological, psychiatric, or medical disease. It discusses aging-related changes in many brain functions, including memory, language, sensory perception, motor function, creativity, attention, executive functions, emotions and mood. The neural mechanisms that may account for specific aging-related changes in cognition, perception and behavior are explored, as well as the means by which aging-related cognitive decrements can be managed and possibly ameliorated. Consequently, this book will be of value to clinicians, including neurologists, psychiatrists, geriatricians, primary care physicians, psychologists and speech-language pathologists. In addition, researchers and graduate students who want to learn about the aging brain will find this an indispensable guide.

Brain Networks for Studying Healthy and Pathological Aging Mechanisms and Intervention Efficacy

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889661229
Total Pages : 577 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Brain Networks for Studying Healthy and Pathological Aging Mechanisms and Intervention Efficacy by : Christos Frantzidis

Download or read book Brain Networks for Studying Healthy and Pathological Aging Mechanisms and Intervention Efficacy written by Christos Frantzidis and published by Frontiers Media SA. This book was released on 2020-11-18 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Previous studies showed that both healthy and pathological aging are associated with changes in brain structure and function of the mature human brain. The most prominent anatomical alteration are changes in prefrontal cortex morphology, volume loss and reduced white-matter integrity and hippocampal atrophy. Cognitive decline affects mainly the performance of episodic memory, speed of sensory information processing, working memory, inhibitory function and long-term memory. It has been also proposed that due to the aforementioned changes the aging brain engages in compensatory brain mechanism such as a broader activation of cortical regions (mainly frontal) rather than specialized activation. Evidence suggests that similar changes occur with pathological aging but to a greater extent. In this case information flow is disrupted due to neurodegeneration, functional activation of posterior (occipito-temporal) regions is decreased and as a consequence the brain fails to process sensorial input in the ventral pathway and cognitive deficits appear. In the last years, functional alterations associated with aging have been studied using the mathematical notion of graph theory that offers an integrative approach since it examines different properties of the brain network: 1) Organization level 2) amount of local information processing, 3) information flow 4) cortical community structure and 5) identification of functional / anatomical hubs. So, graph theory offers an attractive way to model brain networks organization and to quantify their pathological deviations. Previous studies have already employed this mathematical notion and demonstrated that age-related neurodegeneration is often accompanied by loss of optimal network organization either due to diminished local information processing or due to progressive isolation of distant brain regions. They have also found that changes in network properties may be present even in the preclinical phase, which could be taken as a biological marker of disease.

Cognitive and Brain Aging: Interventions to Promote Well-Being in Old Age. Roadmap for Interventions Preventing Cognitive Aging

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889634892
Total Pages : 326 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Cognitive and Brain Aging: Interventions to Promote Well-Being in Old Age. Roadmap for Interventions Preventing Cognitive Aging by : Pamela M. Greenwood

Download or read book Cognitive and Brain Aging: Interventions to Promote Well-Being in Old Age. Roadmap for Interventions Preventing Cognitive Aging written by Pamela M. Greenwood and published by Frontiers Media SA. This book was released on 2020-03-03 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Cambridge Handbook of Cognitive Aging

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Publisher : Cambridge University Press
ISBN 13 : 1108690742
Total Pages : 1019 pages
Book Rating : 4.1/5 (86 download)

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Book Synopsis The Cambridge Handbook of Cognitive Aging by : Ayanna K. Thomas

Download or read book The Cambridge Handbook of Cognitive Aging written by Ayanna K. Thomas and published by Cambridge University Press. This book was released on 2020-05-28 with total page 1019 pages. Available in PDF, EPUB and Kindle. Book excerpt: Decades of research have demonstrated that normal aging is accompanied by cognitive change. Much of this change has been conceptualized as a decline in function. However, age-related changes are not universal, and decrements in older adult performance may be moderated by experience, genetics, and environmental factors. Cognitive aging research to date has also largely emphasized biological changes in the brain, with less evaluation of the range of external contributors to behavioral manifestations of age-related decrements in performance. This handbook provides a comprehensive overview of cutting-edge cognitive aging research through the lens of a life course perspective that takes into account both behavioral and neural changes. Focusing on the fundamental principles that characterize a life course approach - genetics, early life experiences, motivation, emotion, social contexts, and lifestyle interventions - this handbook is an essential resource for researchers in cognition, aging, and gerontology.

Music and the Aging Brain

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Author :
Publisher : Academic Press
ISBN 13 : 0128174234
Total Pages : 476 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Music and the Aging Brain by : Lola Cuddy

Download or read book Music and the Aging Brain written by Lola Cuddy and published by Academic Press. This book was released on 2020-05-28 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Music and the Aging Brain describes brain functioning in aging and addresses the power of music to protect the brain from loss of function and how to cope with the ravages of brain diseases that accompany aging. By studying the power of music in aging through the lens of neuroscience, behavioral, and clinical science, the book explains brain organization and function. Written for those researching the brain and aging, the book provides solid examples of research fundamentals, including rigorous standards for sample selection, control groups, description of intervention activities, measures of health outcomes, statistical methods, and logically stated conclusions. Summarizes brain structures supporting music perception and cognition Examines and explains music as neuroprotective in normal aging Addresses the association of hearing loss to dementia Promotes a neurological approach for research in music as therapy Proposes questions for future research in music and aging

Cognitive Neuroscience of Aging

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Publisher : Oxford University Press
ISBN 13 : 0199372934
Total Pages : 633 pages
Book Rating : 4.1/5 (993 download)

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Book Synopsis Cognitive Neuroscience of Aging by : Roberto Cabeza

Download or read book Cognitive Neuroscience of Aging written by Roberto Cabeza and published by Oxford University Press. This book was released on 2017 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: A rapidly growing body of research has consituted a new discipline that may be called cognitive neuroscience of aging. This book offers an introduction to the topic, useful to both professionals & students in cognitive neuroscience, cognitive psychology, neuroscience, neuropsychology & neurology.

Cognitive Aging

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Publisher : Psychology Press
ISBN 13 : 1135887519
Total Pages : 294 pages
Book Rating : 4.1/5 (358 download)

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Book Synopsis Cognitive Aging by : Denise Park

Download or read book Cognitive Aging written by Denise Park and published by Psychology Press. This book was released on 2012-12-06 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: As our society ages, the topic of cognitive aging is becoming increasingly important. This volume provides an accessible overview of how the cognitive system changes as a function of normal aging. Building on the successful first edition, this volume provide an even more comprehensive coverage of the major issues affecting memory, attention, language, speech and other aspects of cognitive functioning. The essential chapters from the first edition have been thoroughly revised and updated and new chapters have been introduced which draw in neuroscience studies and more applied topics. In addition, contributors were encouraged to ensure their chapters are accessible to students studying the topic for the first time. This therefore makes the volume appealing as a textbook on senior undergraduate and graduate courses.

Cognitive Plasticity in Neurologic Disorders

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Publisher : Oxford University Press, USA
ISBN 13 : 0199965242
Total Pages : 433 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis Cognitive Plasticity in Neurologic Disorders by : Joseph I. Tracy

Download or read book Cognitive Plasticity in Neurologic Disorders written by Joseph I. Tracy and published by Oxford University Press, USA. This book was released on 2014-12-02 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume makes clear that the cognitive and behavioural symptoms of neurologic disorders and syndromes are dynamic and changing. Each chapter describes the neuroplastic processes at work in a particular condition, giving rise to these ongoing cognitive changes.

Brain Repair After Stroke

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Publisher : Cambridge University Press
ISBN 13 : 1139490656
Total Pages : 307 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Brain Repair After Stroke by : Steven C. Cramer

Download or read book Brain Repair After Stroke written by Steven C. Cramer and published by Cambridge University Press. This book was released on 2010-10-28 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing evidence identifies the possibility of restoring function to the damaged brain via exogenous therapies. One major target for these advances is stroke, where most patients can be left with significant disability. Treatments have the potential to improve the victim's quality of life significantly and reduce the time and expense of rehabilitation. Brain Repair After Stroke reviews the biology of spontaneous brain repair after stroke in animal models and in humans. Detailed chapters cover the many forms of therapy being explored to promote brain repair and consider clinical trial issues in this context. This book provides a summary of the neurobiology of innate and treatment-induced repair mechanisms after hypoxia and reviews the state of the art for human therapeutics in relation to promoting behavioral recovery after stroke. Essential reading for stroke physicians, neurologists, rehabilitation physicians and neuropsychologists.

Networks of the Brain

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Publisher : MIT Press
ISBN 13 : 0262528983
Total Pages : 433 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Networks of the Brain by : Olaf Sporns

Download or read book Networks of the Brain written by Olaf Sporns and published by MIT Press. This book was released on 2016-02-12 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: An integrative overview of network approaches to neuroscience explores the origins of brain complexity and the link between brain structure and function. Over the last decade, the study of complex networks has expanded across diverse scientific fields. Increasingly, science is concerned with the structure, behavior, and evolution of complex systems ranging from cells to ecosystems. In Networks of the Brain, Olaf Sporns describes how the integrative nature of brain function can be illuminated from a complex network perspective. Highlighting the many emerging points of contact between neuroscience and network science, the book serves to introduce network theory to neuroscientists and neuroscience to those working on theoretical network models. Sporns emphasizes how networks connect levels of organization in the brain and how they link structure to function, offering an informal and nonmathematical treatment of the subject. Networks of the Brain provides a synthesis of the sciences of complex networks and the brain that will be an essential foundation for future research.

Brain stimulation: from basic research to clinical use

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832507573
Total Pages : 294 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Brain stimulation: from basic research to clinical use by : Alia Benali

Download or read book Brain stimulation: from basic research to clinical use written by Alia Benali and published by Frontiers Media SA. This book was released on 2022-12-08 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Locomotion and Posture in Older Adults

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Author :
Publisher : Springer
ISBN 13 : 3319489801
Total Pages : 457 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Locomotion and Posture in Older Adults by : Fabio Augusto Barbieri

Download or read book Locomotion and Posture in Older Adults written by Fabio Augusto Barbieri and published by Springer. This book was released on 2017-02-07 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an attempt to advance the discussion and improve our understanding about the effects of aging and movement disorders on motor control during walking and postural tasks. Despite these activities are performed daily, there is a high requirement of motor and neural systems in order to perform both tasks efficiently. Both walking and posture require a complex interaction of musculoskeletal and neural systems. However, the mechanisms used to control these tasks, as well as how they are planned and coordinated, are still a question of discussion among health professionals and researchers. In addition, this discussion is more interesting when the effects of aging are included in the context of locomotion and the postural control. The number of older individuals is 841 million in 2015, which is four times higher than the 202 million that lived in 1950. Aging causes many motor, sensorial and neural deficits, which impair locomotion and postural control in the elderly. The severity of this framework is worsened when the aging goes along with a movement disorder, such as Parkinson disease, Chorea, Dystonia, Huntington disease, etc. Therefore, the aim of this book is to highlight the influence of different aspects on planning, controlling and performing locomotion and posture tasks. In attempting to improve current knowledge in this field, invited authors present and discuss how environmental, sensorial, motor, cognitive and individual aspects influence the planning and performance of locomotor and postural activities. The major thrust of the book is to address the mechanisms involved in controlling and planning motor action in neurological healthy individuals, as well as in those who suffer from movement disorders or face the effects of aging, indicating the aspects that impair locomotion and postural control. In addition, new technologies, tools and interventions designed to manage the effects of aging and movement disorders are presented in the book.

Insights in neurocognitive aging and behavior: 2022

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832543758
Total Pages : 407 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Insights in neurocognitive aging and behavior: 2022 by : Kristy A. Nielson

Download or read book Insights in neurocognitive aging and behavior: 2022 written by Kristy A. Nielson and published by Frontiers Media SA. This book was released on 2024-01-30 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: