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Bone Drugs In Pediatrics
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Book Synopsis Bone Drugs in Pediatrics by : Gordon L. Klein
Download or read book Bone Drugs in Pediatrics written by Gordon L. Klein and published by Springer Science & Business Media. This book was released on 2014-04-02 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone Drugs in Pediatrics brings together in one place the evidence for the use of certain drugs in the treatment and prevention of bone loss in children, as well as the reservations still present in the pediatric community regarding their use. Beginning with a discussion of developmental pharmacokinetics and drug development for pediatric diseases where bone loss occurs, such as osteogenesis imperfecta, the physiology of pediatric bone and how best to monitor the safety and efficacy of these drugs is presented. The pros and cons of utilizing the drugs themselves – such as bisphosphonates, antiresorptives and anabolic agents – within the pediatric population are carefully considered, with an eye toward safe and effective integration. The potential use of drugs in future treatment is also highlighted. On the whole, Bone Drugs in Pediatrics is a cogent presentation of the ongoing debate surrounding the potential for pharmacological interventions in pediatric bone loss.
Book Synopsis Calcium and Bone Disorders in Children and Adolescents by : J. Allgrove
Download or read book Calcium and Bone Disorders in Children and Adolescents written by J. Allgrove and published by Karger Medical and Scientific Publishers. This book was released on 2015-06-11 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been a rapid expansion of knowledge in the field of paediatric calcium and bone disorders over the past twenty years. Advances have been made in the underlying genetic basis for many conditions in conjunction with progress in bone density and geometry imaging and the development of new treatment options. The 2nd revised edition of ‘Calcium and Bone Disorders in Children and Adolescents’ presents up-to-date information on many aspects included in the 1st edition such as the physiology, pathology, diagnosis and management of numerous conditions including a chapter of case histories illustrating clinical aspects. New chapters on skeletal dysplasias, the genetics of osteoporosis, radiological imaging of bone and a practical approach to a child with recurrent fractures are included. Providing a comprehensive update, this book is a useful clinical resource for paediatricians and specialists in endocrinology, metabolic bone disease, nephrology, rheumatology, radiology, orthopaedics and clinical genetics who may be faced with a child with a calcium and/or bone disorder.
Book Synopsis Bone Health in Children by : Steven A. Abrams
Download or read book Bone Health in Children written by Steven A. Abrams and published by CRC Press. This book was released on 2012-03-20 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone health is one of the most widely discussed topics in pediatric nutrition. Ensuring adequate calcium and vitamin D intake is essential, and other factors also play a significant role. Bone Health in Children explores the recent decades of research and public commentary on the subject, debunks popular myths, and clarifies the often confusing and contradictory scientific literature. Presenting practical and theoretical education and advice, the book provides rational and accessible information geared to a wide audience of individuals interested in this critical element of pediatric health. Highlights include: The Institute of Medicine process by which Dietary Reference Intakes (DRIs) are developed Iron, calcium, and vitamin D requirements for infants, children, and pregnant and lactating women Controversy over high-dose vitamin D supplementation and pregnancy Detailed explanation of the scientific research process related to human nutrition The nonbone health aspects of vitamin D and why literature claims about this topic can be misleading Frequently Asked Questions regarding nutrition with answers in short format Providing a solid understanding as to how dietary guidelines are developed and evaluating the strengths and weaknesses of their underlying data, this volume answers practical questions crucial for choosing diets for children while also delving into the more theoretical aspects of conducting and interpreting medical research.
Book Synopsis Bone Health Assessment in Pediatrics by : Ellen B. Fung
Download or read book Bone Health Assessment in Pediatrics written by Ellen B. Fung and published by Springer. This book was released on 2016-09-09 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: The gold-standard resource for evaluating bone health in children and adolescents, this practical and highly anticipated second edition offers a comprehensive, fully updated resource for addressing bone health in these populations. Developed by a renowned international panel of experts in measuring and analyzing bone density in the pediatric patient and reflecting the 2013 International Society for Clinical Densitometry (ISCD) Guidelines for Pediatric DXA assessment, interpretation and reporting, this indispensable reference covers all the important changes in the field over the last 9 years. Some highlights of this edition include: an entire chapter on the assessment of infants and toddlers, a chapter devoted to the assessment of children with disabling conditions, an in-depth discussion of vertebral fracture and its etiologies, and a thorough review of the advantages and limitations of densitometry techniques including DXA, pQCT, HRpQCT, and MRI. New fracture prediction software, including Trabecular Bone Score and Finite Element Analysis, is described. In this edition, the limitations of DXA are addressed as are the most recent strategies for handling them including proposed DXA adjustments such as height Z-score. Solidifying itself as the leading text in the field, Bone Health Assessment in Pediatrics: Guidelines for Clinical Practice, 2nd edition provides all of the critical basic analysis and evaluation tools, images, and calculations necessary for clinical practice.
Book Synopsis Pediatric Drug Development by : Andrew E. Mulberg
Download or read book Pediatric Drug Development written by Andrew E. Mulberg and published by John Wiley & Sons. This book was released on 2013-05-20 with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most medicines have never been adequately tested for safety and efficacy in pediatric populations and preterm, infants and children are particularly vulnerable to adverse drug reactions. Pediatric Drug Development: Concepts and Applications, Second Edition, addresses the unique challenges in conducting effective drug research and development in pediatric populations. This new edition covers the legal and ethical issues of consent and assent, the additional legal and safety protections for children, and the appropriate methods of surveillance and assessment for children of varying ages and maturity, particularly for patient reported outcomes. It includes new developments in biomarkers and surrogate endpoints, developmental pharmacology and other novel aspects of global pediatric drug development. It also encompasses the new regulatory initiatives across EU, US and ROW designed to encourage improved access to safe and effective medicines for children globally. From an international team of expert contributors Pediatric Drug Development: Concepts and Applications is the practical guide to all aspects of the research and development of safe and effective medicines for children.
Author :United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products Publisher : ISBN 13 : Total Pages :16 pages Book Rating :4.:/5 (319 download)
Book Synopsis Guidelines for the Clinical Evaluation of Drugs Used in the Treatment of Osteoporosis by : United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products
Download or read book Guidelines for the Clinical Evaluation of Drugs Used in the Treatment of Osteoporosis written by United States. Food and Drug Administration. Division of Metabolism and Endocrine Drug Products and published by . This book was released on 1979 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Osteoporosis: Secondary Osteoporosis and Pediatric Concerns by : Dan Heller
Download or read book Osteoporosis: Secondary Osteoporosis and Pediatric Concerns written by Dan Heller and published by . This book was released on 2015-01-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteoporosis is a serious health problem across the globe. In the last few years, growth has been seen in the knowledge of the pathophysiological mechanism of the disease. Modern technologies have added significant information in bone mineral density measurements and, furthermore, mechanical and geometrical properties of bone. Novel bone indices have been formulated from hormonal and biochemical measurements for the investigation of bone metabolism. Although, it is evident that drugs are a crucial part of the therapy. However, beyond medication, there are other interventions in the management of the disease. Prevention of this disease begins at young age and goes on with the process of aging for the purpose of prevention of fractures related to the impaired quality of life, mortality, physical decline, and high cost for the health system. Several distinct specialties are holding the scientific knowledge in this disease. In this book, information from scientific departments from across the world has been compiled. Updated information regarding pediatric issues and secondary osteoporosis has been compiled extensively in this book.
Book Synopsis Drug Toxicity and Metabolism in Pediatrics by : Sam Kacew
Download or read book Drug Toxicity and Metabolism in Pediatrics written by Sam Kacew and published by CRC Press. This book was released on 2018-01-18 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this text is to examine the physiological development of the fetus. It allows the reader to study the unique pharmacokinetic and metabolic features of newborns and gives specific examples of drug metabolism in the newborn. The purpose of this book is to enhance the current knowledge of pharmacology of the newborn by observing the embryo and placenta in normal and abnormal development, placental transfer of drugs, metabolic pathways, and metabolism of specific drugs such as theophylline, benzodiazepines, and antibiotics. This is a useful book for those involved in pediatric research, pharmacology, toxicology, experimental therapeutics and biology.
Book Synopsis Pediatric Orthopaedics and Sports Medicine by : John P. Dormans
Download or read book Pediatric Orthopaedics and Sports Medicine written by John P. Dormans and published by Elsevier Health Sciences. This book was released on 2004 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical volume in the Clinical Practice in Pediatric series focuses on the assessment and stabilization of injuries commonly encountered in clinical practice. Topics and categories are organized to address all of the major categories of disease and trauma involving the musculoskeletal system in infants and children. Tables highlight diagnosis, laboratory and radiologic studies, therapies, and when to refer to a specialist. Key points at the end of each chapter highlight vital information.
Book Synopsis Pediatric Pharmacotherapy by : Wieland Kiess
Download or read book Pediatric Pharmacotherapy written by Wieland Kiess and published by Springer Nature. This book was released on 2020-07-15 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides readers with the most updated scientific information on the efficacy and safety of medicines for children and adolescents. The book enriches the understanding of pediatric pharmacotherapy for health professionals, regulatory agencies, pharmaceutical companies and learned societies. It contains important information on the pharmacodynamics and pharmacokinetics of drugs. It summarizes the latest investigations on the effects of pharmacological treatments in relation to and dependent on age, gender, fat mass and disease status. Therefore and importantly, this volume reviews the latest data on how pharmacotherapy has to be adjusted and personalized in regards to stages of development and during the pediatric lifespan from neonate through adolescence. In addition, the topic of rare diseases and special challenges for pharmacotherapy will be included and will provide readers with the necessary knowledge to handle complex diseases and treatment strategies especially in relation to pharmacotherapy of rare and orphan diseases.
Book Synopsis Safe and Effective Medicines for Children by : Institute of Medicine
Download or read book Safe and Effective Medicines for Children written by Institute of Medicine and published by National Academies Press. This book was released on 2012-10-13 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Best Pharmaceuticals for Children Act (BPCA) and the Pediatric Research Equity Act (PREA) were designed to encourage more pediatric studies of drugs used for children. The FDA asked the IOM to review aspects of pediatric studies and changes in product labeling that resulted from BPCA and PREA and their predecessor policies, as well as assess the incentives for pediatric studies of biologics and the extent to which biologics have been studied in children. The IOM committee concludes that these policies have helped provide clinicians who care for children with better information about the efficacy, safety, and appropriate prescribing of drugs. The IOM suggests that more can be done to increase knowledge about drugs used by children and thereby improve the clinical care, health, and well-being of the nation's children.
Book Synopsis Pediatric Bone and Soft Tissue Sarcomas by : Alberto S. Pappo
Download or read book Pediatric Bone and Soft Tissue Sarcomas written by Alberto S. Pappo and published by Springer Science & Business Media. This book was released on 2005-12-31 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of pediatric bone and soft tissue sarcomas has experienced a gradual but surprising transformation. Fundamental discoveries in the molecular biology of disease, recent breakthroughs in diagnostic imaging, and revolutionary surgical techniques have created unprecedented synergies and a refreshing vision with which to approach the diagnosis and treatment of these pediatric tumors. This book highlights the paths leading to the emergence of such a new vision and presents salient concepts in epidemiology, novel tools in imaging and molecular biology, and principles of drug development as the scaffold to understanding the pathophysiology and treatment of pediatric sarcomas. The book is aimed at providing an up-to-date comprehensive reference text which articulates a multidisciplinary approach for the diagnosis and treatment of each of these often challenging diseases.
Book Synopsis Bone Health and Osteoporosis by : United States Public Health Service
Download or read book Bone Health and Osteoporosis written by United States Public Health Service and published by . This book was released on 2004-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first-ever Surgeon General's Report on bone health and osteoporosis illustrates the large burden that bone disease places on our Nation and its citizens. Like other chronic diseases that disproportionately affect the elderly, the prevalence of bone disease and fractures is projected to increase markedly as the population ages. If these predictions come true, bone disease and fractures will have a tremendous negative impact on the future well-being of Americans. But as this report makes clear, they need not come true: by working together we can change the picture of aging in America. Osteoporosis, fractures, and other chronic diseases no longer should be thought of as an inevitable part of growing old. By focusing on prevention and lifestyle changes, including physical activity and nutrition, as well as early diagnosis and appropriate treatment, Americans can avoid much of the damaging impact of bone disease and other chronic diseases. This Surgeon General's Report brings together for the first time the scientific evidence related to the prevention, assessment, diagnosis, and treatment of bone disease. More importantly, it provides a framework for moving forward. The report will be another effective tool in educating Americans about how they can promote bone health throughout their lives. This first-ever Surgeon General's Report on bone health and osteoporosis provides much needed information on bone health, an often overlooked aspect of physical health. This report follows in the tradition of previous Surgeon Generals' reports by identifying the relevant scientific data, rigorously evaluating and summarizing the evidence, and determining conclusions.
Book Synopsis Handbook of Pediatric Transfusion Medicine by : Christopher D. Hillyer
Download or read book Handbook of Pediatric Transfusion Medicine written by Christopher D. Hillyer and published by Elsevier. This book was released on 2004-02-23 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structured to be a companion to the recently published Handbook of Transfusion Medicine, the Handbook of Pediatric Transfusion Medicine is dedicated to pediatric hematology-oncology and transfusion medicine, a field which remains ambiguous and which has generated few comprehensive texts. This book stands alone as one of the few texts that addresses transfusion issues specific to pediatric medicine. Written in an eminently readable style, this authoritative handbook is a requirement for any pediatric physician or caregiver. Neonatal and fetal immune response and in utero development issues Blood compatability and pre-transfusion testing issues specific to pediatric and neonatal transfusion Therapeutic apheresis including red blood cell exchange and prophylactic chronic erythrocytapheresis for sickle cell patients Also includes a section that concentrates on the consent, quality and legal issues of blood transfusion and donation
Book Synopsis Anabolic Treatments for Osteoporosis by : James F. Whitfield
Download or read book Anabolic Treatments for Osteoporosis written by James F. Whitfield and published by CRC Press. This book was released on 2013-11-12 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteoporosis, a growing epidemic among women in North America, Europe, and Japan, is a painful, costly disease that has presented a treatment challenge to healthcare professionals. Until recently, therapies have focused on agents that slow bone resorption, and have had only limited success at increasing bone mass.
Book Synopsis Pediatric Bone Marrow by : Lila Penchansky
Download or read book Pediatric Bone Marrow written by Lila Penchansky and published by Springer Science & Business Media. This book was released on 2003-12-03 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: No other book covers the pathology of the bone marrow in children as extensively as Pediatric Bone Marrow. It provides a wide background for the understanding of bone marrow disease in children and its difference from that of the adult population. The text illustrates the morphology of the peripheral blood, bone marrow aspirate and bone marrow biopsy. It is useful for the diagnosis of pediatric disorders in the bone marrow, making it an ideal guide for pediatric pathologists, hematologists, oncologists and medical technologists or any physician involved in the diagnosis of pediatric bone marrow disorders.
